المؤلفون: Allyn T. Londregan (1463164), Karlygash Aitmakhanova (14298913), James Bennett (154826), Laura J. Byrnes (14298916), Daniel P. Canterbury (2022946), Xiayun Cheng (1322244), Thomas Christott (5902688), Jennifer Clemens (1696795), Steven B. Coffey (1463167), João M. Dias (12707543), Matthew S. Dowling (1523953), Gillian Farnie (282327), Oleg Fedorov (244326), Kimberly F. Fennell (2182748), Vicki Gamble (3807208), Carina Gileadi (1385442), Charline Giroud (5902694), Michael R. Harris (399139), Brett D. Hollingshead (9300522), Kilian Huber (625910), Magdalena Korczynska (1327899), Kimberly Lapham (1656913), Paula M. Loria (1600666), Arjun Narayanan (197239), Dafydd R. Owen (1290468), Brigitt Raux (1444024), Parag V. Sahasrabudhe (2948502), Roger B. Ruggeri (1738840), Laura Díaz Sáez (14298919), Ingrid A. Stock (1656904), Benjamin A. Thuma (2204773), Andy Tsai (1721833), Alison E. Varghese (14298922)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Evolutionary Biology, Immunology, Cancer, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, vitro safety profiles, quality probe molecules, ongoing research effort, challenging epigenetic targets, demonstrate excellent potency, epigenetic reader yeats4, 4e , 4d , molecule yeats4 binders, molecule binders, nanomolar potency, capable binders, yeats domain, new x

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_High-Affinity_Small-Molecule_Binders_of_the_Epigenetic_Reader_YEATS4/21777304

الاتاحة: https://doi.org/10.1021/acs.jmedchem.2c01421.s001

المؤلفون: Allyn T. Londregan (1463164), Karlygash Aitmakhanova (14298913), James Bennett (154826), Laura J. Byrnes (14298916), Daniel P. Canterbury (2022946), Xiayun Cheng (1322244), Thomas Christott (5902688), Jennifer Clemens (1696795), Steven B. Coffey (1463167), João M. Dias (12707543), Matthew S. Dowling (1523953), Gillian Farnie (282327), Oleg Fedorov (244326), Kimberly F. Fennell (2182748), Vicki Gamble (3807208), Carina Gileadi (1385442), Charline Giroud (5902694), Michael R. Harris (399139), Brett D. Hollingshead (9300522), Kilian Huber (625910), Magdalena Korczynska (1327899), Kimberly Lapham (1656913), Paula M. Loria (1600666), Arjun Narayanan (197239), Dafydd R. Owen (1290468), Brigitt Raux (1444024), Parag V. Sahasrabudhe (2948502), Roger B. Ruggeri (1738840), Laura Díaz Sáez (14298919), Ingrid A. Stock (1656904), Benjamin A. Thuma (2204773), Andy Tsai (1721833), Alison E. Varghese (14298922)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Evolutionary Biology, Immunology, Cancer, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, vitro safety profiles, quality probe molecules, ongoing research effort, challenging epigenetic targets, demonstrate excellent potency, epigenetic reader yeats4, 4e , 4d , molecule yeats4 binders, molecule binders, nanomolar potency, capable binders, yeats domain, new x

Relation: https://figshare.com/articles/dataset/Discovery_of_High-Affinity_Small-Molecule_Binders_of_the_Epigenetic_Reader_YEATS4/21777307

الاتاحة: https://doi.org/10.1021/acs.jmedchem.2c01421.s002