المؤلفون: Xiaoke Chi, Dang Nguyen, James M Pemberton, Elizabeth J Osterlund, Qian Liu, Hetal Brahmbhatt, Zhi Zhang, Jialing Lin, Brian Leber, David W Andrews

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: primary murine neurons, MEF cells, BMK cells, apoptosis, Bcl-2 family proteins, mitochondrial outer membrane permeabilization, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/44525; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/3930186c3fd04ad4a33907088e2464c2

المؤلفون: Qian Liu, Elizabeth J Osterlund, Xiaoke Chi, Justin Pogmore, Brian Leber, David William Andrews

المصدر: eLife, Vol 8 (2019)

مصطلحات موضوعية: Bcl-2 family proteins, apoptosis, BH3-mimetic drugs, tissue culture cells, fluorescence lifetime imaging, Forster resonance energy transfer, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/37689; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/35be500a47c444d396b9241785a6b15f

المؤلفون: David W. Andrews, Jialing Lin, Qian Liu, Dang Nguyen, Xiaoke Chi, Hetal Brahmbhatt, James M. Pemberton, Brian Leber, Zhi Zhang, Elizabeth J Osterlund

مصطلحات موضوعية: Terminal (electronics), Chemistry, Sequence (medicine), Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2e5d9195bdd01553fa821926258cef26
https://doi.org/10.7554/elife.44525.sa2

المؤلفون: David W. Andrews, Xiaoke Chi, Justin Pogmore, Elizabeth J Osterlund, Brian Leber, Qian Liu

المصدر: eLife, Vol 8 (2019)
eLife

مصطلحات موضوعية: 0301 basic medicine, Forster resonance energy transfer, Tumor initiation, 0302 clinical medicine, Neoplasms, Fluorescence Resonance Energy Transfer, Image Processing, Computer-Assisted, Biology (General), Cancer Biology, chemistry.chemical_classification, biology, Bcl-2-Like Protein 11, Chemistry, General Neuroscience, apoptosis, General Medicine, fluorescence lifetime imaging, 3. Good health, Cell biology, Amino acid, Proto-Oncogene Proteins c-bcl-2, 030220 oncology & carcinogenesis, Disease Progression, MCF-7 Cells, Medicine, biological phenomena, cell phenomena, and immunity, Research Article, Programmed cell death, QH301-705.5, Science, bcl-X Protein, Bcl-xL, Antineoplastic Agents, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Protein Domains, Cell Line, Tumor, None, Humans, Binding site, General Immunology and Microbiology, BH3-mimetic drugs, Cell Biology, Bcl-2 family proteins, tissue culture cells, 030104 developmental biology, Förster resonance energy transfer, Apoptosis, Drug Resistance, Neoplasm, Cancer cell, biology.protein, Apoptosis Regulatory Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe78005316b30836ed30ece7081684d8
https://elifesciences.org/articles/37689

المؤلفون: Qian Liu, Xiaoke Chi, Justin Pogmore, Elizabeth J Osterlund, Brian Leber, David W. Andrews

مصطلحات موضوعية: Bh3 mimetic, biology, Chemistry, Anti cancer drugs, Cancer research, biology.protein, Displacement (orthopedic surgery), Bcl-xL

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7a10b267e368b9b14aab0319f9743e04
https://doi.org/10.7554/elife.37689.042

المؤلفون: Zhi Zhang, Dang Nguyen, Xiaoke Chi, David W. Andrews, Elizabeth J Osterlund, Hetal Brahmbhatt, Brian Leber, James M. Pemberton, Jialing Lin, Qian Liu

المصدر: eLife
eLife, Vol 9 (2020)

مصطلحات موضوعية: 0301 basic medicine, Structural Biology and Molecular Biophysics, Mutant, Sequence (biology), Mitochondrion, 0302 clinical medicine, hemic and lymphatic diseases, Biology (General), Inner mitochondrial membrane, Cells, Cultured, bcl-2-Associated X Protein, mitochondrial outer membrane permeabilization, Cerebral Cortex, Neurons, 0303 health sciences, Bcl-2-Like Protein 11, Chemistry, General Neuroscience, apoptosis, General Medicine, BMK cells, Cell biology, Mitochondria, Membrane, 030220 oncology & carcinogenesis, Mitochondrial Membranes, Molecular mechanism, Medicine, biological phenomena, cell phenomena, and immunity, Research Article, QH301-705.5, Science, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Protein Domains, None, Animals, Humans, MEF cells, 030304 developmental biology, General Immunology and Microbiology, Molecular biophysics, Cell Biology, HCT116 Cells, nervous system diseases, Bcl-2 family proteins, Mice, Inbred C57BL, 030104 developmental biology, HEK293 Cells, Structural biology, Apoptosis, primary murine neurons

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fea2501e20063cec39d32828271031d
https://pubmed.ncbi.nlm.nih.gov/31976859

المؤلفون: Christian, Bogner, Justin, Kale, Justin, Pogmore, Xiaoke, Chi, Aisha, Shamas-Din, Cécile, Fradin, Brian, Leber, David W, Andrews

المصدر: Molecular cell. 77(4)

مصطلحات موضوعية: Mice, Allosteric Regulation, Mitochondrial Membranes, bcl-X Protein, Animals, Humans, Apoptosis, bcl-Associated Death Protein, BH3 Interacting Domain Death Agonist Protein, Cell Line, bcl-2-Associated X Protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1aad7ee0c2c7ff0df891f24d4b5e64d4
https://pubmed.ncbi.nlm.nih.gov/32001105

المؤلفون: David W. Andrews, Brian Leber, Scott Bindner, Xiaoke Chi, Cécile Fradin, Aisha Shamas-Din

المصدر: Biochemical Journal. 467:495-505

مصطلحات موضوعية: Cardiolipins, Protein Conformation, Truncated BID, Membrane lipids, Apoptosis, Mitochondria, Liver, Mitochondrion, Biology, Models, Biological, Biochemistry, Permeability, Membrane Lipids, Mice, chemistry.chemical_compound, Proto-Oncogene Proteins, Cardiolipin, Animals, Humans, Molecular Biology, bcl-2-Associated X Protein, Mice, Knockout, Bcl-2-Like Protein 11, Activator (genetics), Bcl-2 family, Membrane Proteins, Cell Biology, Mitochondrial carrier, Recombinant Proteins, Cell biology, Cholesterol, bcl-2 Homologous Antagonist-Killer Protein, chemistry, Liposomes, Mitochondrial Membranes, Mutagenesis, Site-Directed, Apoptosis Regulatory Proteins, Bacterial outer membrane, BH3 Interacting Domain Death Agonist Protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b922ec04b2e280934f73f9332b33cb
https://doi.org/10.1042/bj20141291

المؤلفون: Christian Bogner, Xiaoke Chi, Aisha Shamas-Din, Cécile Fradin, Justin Kale, Justin Pogmore, Brian Leber, David W. Andrews

المصدر: Molecular Cell. 77:901-912.e9

مصطلحات موضوعية: 0303 health sciences, Programmed cell death, biology, Activator (genetics), Bcl-2 family, Allosteric regulation, Bcl-xL, Cell Biology, Mitochondrion, law.invention, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Apoptosis, law, biology.protein, Recombinant DNA, biological phenomena, cell phenomena, and immunity, Molecular Biology, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a3bb73c9305b9a12b47ccf62a98bf9a0
https://doi.org/10.1016/j.molcel.2019.12.025

المؤلفون: Xiaoke Chi, Justin Kale, Brian Leber, David W. Andrews

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1843:2100-2113

مصطلحات موضوعية: Programmed cell death, Protein Conformation, Cell, Apoptosis, Biology, Mitochondrion, Mitochondrial Dynamics, Models, Biological, Cell membrane, Bcl-2 family, medicine, Animals, Humans, Molecular Biology, Endoplasmic reticulum, Cell Membrane, Membrane, Cell Biology, Cell biology, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-2, Biochemistry, Cytoplasm, Embedded Together, Bacterial outer membrane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426400eac86a513681630f24602c66ce
https://doi.org/10.1016/j.bbamcr.2014.06.002

المؤلفون: John A. Bachman, Luv Patel, Annabelle Flanagan, David W. Andrews, Kristopher A. Sarosiek, Xiaoke Chi, Joshua J. Sims, Anthony Letai, Peter K. Sorger, Joan Montero

المصدر: Molecular Cell. 51(6):751-765

مصطلحات موضوعية: Transcriptional Activation, Programmed cell death, medicine.drug_class, Topoisomerase Inhibitors, Apoptosis, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Proto-Oncogene Proteins, medicine, Humans, Molecular Biology, 030304 developmental biology, Neoplasm Staging, bcl-2-Associated X Protein, Antitumor activity, Regulation of gene expression, Ovarian Neoplasms, 0303 health sciences, Bcl-2-Like Protein 11, Activator (genetics), Membrane Proteins, Cell Biology, Cell biology, Mitochondria, Gene Expression Regulation, Neoplastic, bcl-2 Homologous Antagonist-Killer Protein, 030220 oncology & carcinogenesis, Female, biological phenomena, cell phenomena, and immunity, Apoptosis Regulatory Proteins, Homeostasis, Topoisomerase inhibitor, Chemotherapy response, BH3 Interacting Domain Death Agonist Protein, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699df16af74d0c19267784c25eb8c2ef

المؤلفون: Justin P, Pogmore, James M, Pemberton, Xiaoke, Chi, David W, Andrews

المصدر: Methods in molecular biology (Clifton, N.J.). 1419

مصطلحات موضوعية: Mice, Proto-Oncogene Proteins c-bcl-2, Mitochondrial Membranes, Fluorescence Resonance Energy Transfer, bcl-X Protein, Animals, Cytochromes c, Humans, Apoptosis, Protein Interaction Maps, BH3 Interacting Domain Death Agonist Protein, Mitochondria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::da5ce9b094d6329da04a39cae1ee5a10
https://pubmed.ncbi.nlm.nih.gov/27108441

المؤلفون: Robert Amson, Joane Honoré, Stephanie B. Telerman, Xiaoke Chi, Laurent Maillet, Fabien Gautier, Philippe Juin, Nathalie Troffer-Charlier, Sarah Cianférani, Teele Karafin, Sylvie Montessuit, Morgane Agez, Jean Cavarelli, V. Cura, Andrea Senff-Ribeiro, Catherine Birck, Adam Telerman, Stéphanie Thébault, Christopher M. Johnson, Isabelle Billas-Massobrio, Johann Stojko, Jean-Claude Martinou, David W. Andrews

المساهمون: Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Biologie et de Technologies de Saclay (IBITECS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, McMaster University [Hamilton, Ontario], Laboratoire de Spectrométrie de Masse BioOrganique [Strasbourg] (LSMBO), Département Sciences Analytiques et Interactions Ioniques et Biomoléculaires (DSA-IPHC), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de génétique et biologie moléculaire et cellulaire (IGBMC), Université Louis Pasteur - Strasbourg I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche en Cancérologie Nantes-Angers (CRCNA), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM)-Hôtel-Dieu de Nantes-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Laennec-Centre National de la Recherche Scientifique (CNRS)-Faculté de Médecine d'Angers-Centre hospitalier universitaire de Nantes (CHU Nantes), Laboratoire de Biologie et de Pharmacologie Appliquée (LBPA), Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Cachan (ENS Cachan), Biomarqueurs prédictifs et nouvelles stratégies moléculaires en thérapeutique anticancéreuse (U981), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Cell Biology, University of Geneva [Switzerland], ExxonMobil Exploration Company, Subsurface Characterization, Global Tectonics & Structure, Swedish Institute of Space Physics [Uppsala] (IRF), Institut Gustave Roussy (IGR), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), Sunnybrook Research Institute [Toronto] (SRI), Sunnybrook Health Sciences Centre, University of Toronto, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), King‘s College London, Laboratory of Molecular Biology [Cambridge], Medical Research Council, Institut de Cancérologie de l'Ouest [Angers/Nantes] (UNICANCER/ICO), UNICANCER, Université de Genève = University of Geneva (UNIGE), Bernardo, Elizabeth

المصدر: Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6 (1), pp.19725. ⟨10.1038/srep19725⟩
Scientific Reports, Nature Publishing Group, 2015, 6, pp.19725. ⟨10.1038/srep19725⟩
Scientific Reports, 2015, 6 (1), pp.19725. ⟨10.1038/srep19725⟩
'Scientific Reports ', vol: 6, pages: 19725-1-19725-11 (2016)
Thébault, S, Agez, M, Chi, X, Stojko, J, Cura, V, Telerman, S B, Maillet, L, Gautier, F, Billas-Massobrio, I, Birck, C, Troffer-Charlier, N, Karafin, T, Honoré, J, Senff-Ribeiro, A, Montessuit, S, Johnson, C M, Juin, P, Cianférani, S, Martinou, J-C, Andrews, D W, Amson, R, Telerman, A & Cavarelli, J 2016, ' TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL ', Scientific Reports, vol. 6, 19725 . https://doi.org/10.1038/srep19725

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Cell Membrane Permeability, Protein Conformation, [SDV]Life Sciences [q-bio], bcl-X Protein, Bcl-xL, Apoptosis, [SDV.CAN]Life Sciences [q-bio]/Cancer, Plasma protein binding, Article, 03 medical and health sciences, Mice, Bcl-2-associated X protein, Protein structure, [SDV.CAN] Life Sciences [q-bio]/Cancer, Translationally-controlled tumor protein, Biomarkers, Tumor, Animals, Protein Interaction Domains and Motifs, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Amino Acid Sequence, Peptide sequence, bcl-2-Associated X Protein, Multidisciplinary, biology, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Tumor Protein, Translationally-Controlled 1, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Molecular biology, 3. Good health, Cell biology, 030104 developmental biology, Structural biology, Multiprotein Complexes, biology.protein, Protein Multimerization, biological phenomena, cell phenomena, and immunity, Function (biology), BH3 Interacting Domain Death Agonist Protein, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7023a54dd9aaa04d62bc1832bfa2e4d
https://hal.archives-ouvertes.fr/hal-02412783

المؤلفون: Justin Pogmore, James M. Pemberton, Xiaoke Chi, David W. Andrews

المصدر: Methods in Molecular Biology ISBN: 9781493935796

مصطلحات موضوعية: 0301 basic medicine, biology, Chemistry, Cytochrome c, Bcl-2 family, Mitochondrion, Mitochondrial carrier, Cell biology, Protein–protein interaction, 03 medical and health sciences, Mitochondrial membrane transport protein, 030104 developmental biology, 0302 clinical medicine, Translocase of the inner membrane, biology.protein, Bacterial outer membrane, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fe20988f66f5fdda8d19b1a8fd12c0f4
https://doi.org/10.1007/978-1-4939-3581-9_15

المؤلفون: Justin, Kale, Xiaoke, Chi, Brian, Leber, David, Andrews

المصدر: Methods in enzymology. 544

مصطلحات موضوعية: Cell Membrane Permeability, Spectrometry, Fluorescence, Proto-Oncogene Proteins c-bcl-2, Protein Conformation, Cell Membrane, Liposomes, Protein Interaction Mapping, Animals, Humans, Apoptosis, BH3 Interacting Domain Death Agonist Protein, Mitochondria, bcl-2-Associated X Protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::8929e9c7bfc352c4e753d6462662da24
https://pubmed.ncbi.nlm.nih.gov/24974284

المؤلفون: Xiaoke Chi, David W. Andrews, Justin Kale, Brian Leber

مصطلحات موضوعية: Membrane, Förster resonance energy transfer, Quenching (fluorescence), Apoptosis, Protein dynamics, Bcl-2 family, Biology, Fluorescence spectroscopy, Intracellular, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::16bef6f4774204f961c6d04e59b0c002
https://doi.org/10.1016/b978-0-12-417158-9.00001-7

المؤلفون: Qian Liu, Brian Leber, David W. Andrews, Xiaoke Chi

المصدر: Cell Death ISBN: 9781461493013

مصطلحات موضوعية: Multicellular organism, Programmed cell death, medicine.anatomical_structure, Apoptosis, Cancer cell, Cell, Bcl-2 family, Cancer research, medicine, Cancer, Mitochondrion, Biology, medicine.disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d61b03d6fc7786572a7e18aa1752e938
https://doi.org/10.1007/978-1-4614-9302-0_4

المؤلفون: Xiaoke Chi, Duanqing Pei, Zhe Wang, Tianhua Ma

المصدر: The Journal of biological chemistry. 283(8)

مصطلحات موضوعية: Homeobox protein NANOG, Pluripotent Stem Cells, Rex1, Recombinant Fusion Proteins, Biology, Biochemistry, Leukemia Inhibitory Factor, Cell Line, Transactivation, Amino Acids, Aromatic, Mice, Animals, Humans, Induced pluripotent stem cell, Molecular Biology, reproductive and urinary physiology, Embryonic Stem Cells, Homeodomain Proteins, Nanog Homeobox Protein, Cell Differentiation, Herpes Simplex Virus Protein Vmw65, Cell Biology, Cell Dedifferentiation, Fibroblasts, Molecular biology, Embryonic stem cell, Protein Structure, Tertiary, DNA-Binding Proteins, Amino Acid Substitution, Cell culture, embryonic structures, Trans-Activators, biological phenomena, cell phenomena, and immunity, Reprogramming

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527c9c5f78951414e3a637f87d87895e
https://pubmed.ncbi.nlm.nih.gov/18086680

المؤلفون: Kristopher A. Sarosiek, Anthony Letai, Luv Patel, Peter K. Sorger, Joshua J. Sims, David W. Andrews, Xiaoke Chi, John A. Bachman, Joan Montero

المصدر: Cancer Research. 73:1713-1713

مصطلحات موضوعية: Cisplatin, Cancer Research, Programmed cell death, medicine.drug_class, Pharmacology, Biology, chemistry.chemical_compound, Oncology, Paclitaxel, chemistry, Apoptosis, medicine, Doxorubicin, Topotecan, biological phenomena, cell phenomena, and immunity, Topoisomerase inhibitor, Etoposide, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f75269d22e69cc0d4a3c13e74d28fdbb
https://doi.org/10.1158/1538-7445.am2013-1713

المؤلفون: Zhe Wang, Duanqing Pei, Xiaoke Chi, Tianhua Ma

المصدر: Journal of Biological Chemistry. 284:11748

مصطلحات موضوعية: Homeobox protein NANOG, business.industry, Cell Biology, Biology, Self renewal, Biochemistry, Embryonic stem cell, Chinese academy of sciences, Regenerative medicine, Cell biology, Additions and Corrections, business, Molecular Biology, Biological sciences, Stem cell biology, Biomedicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131be6d0c3bfcface9cfff065b8740db
https://doi.org/10.1074/jbc.a706009200