المؤلفون: Xiao-Ling Cockcroft, Stephan Karl Zahn, Mark Petronczki, Catherine M. Rogers, Fengling Li, Helmut Berger, Bernadette Sharps, Markus Zeeb, Ralph A. Neumüller, Mark Pearson, Dalia Barsyte-Lovejoy, Teresa Krammer, Oleg Fedorov, Barbara Müllauer, Alexander Weiss-Puxbaum, Kilian Huber, Masoud Vedadi, Magdalena M. Szewczyk, Christopher R. Vakoc, Abdellah Allali-Hassani, Tobias Wunberg, Steven Kennedy, Christoph Reiser, Michael Schleicher, Julian E. Fuchs, Cheryl H. Arrowsmith, Moriz Mayer, Jark Böttcher, Guido Boehmelt, Dietrich Böse, Alexandra Hörmann, Andreas Zoephel, Heribert Arnhof, Sandra Winkler, Darryl B. McConnell, Peter Brown, David Dilworth, Maja Corcokovic, Klaus Rumpel, Thomas Gerstberger, Nikolai Mischerikow, Carrow I. Wells, Ulrich Reiser, Daniela Häring

المصدر: Nature Chemical Biology. 15:822-829

مصطلحات موضوعية: Messenger RNA, Cell Survival, Chemistry, Protein domain, Nuclear Proteins, Myeloid leukemia, Histone-Lysine N-Methyltransferase, Cell Biology, Amplicon, medicine.disease, In vitro, Cell Line, Chromatin, Cell biology, Proto-Oncogene Proteins c-myc, Leukemia, Gene Expression Regulation, Protein Domains, medicine, Humans, CRISPR-Cas Systems, Binding site, Molecular Biology, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27dc86073fff4580d870ac18a39c74e3
https://doi.org/10.1038/s41589-019-0310-x

المؤلفون: Harald Engelhardt, Xiao-Ling Cockcroft, Leonhard Geist, Bernhard Wolkerstorfer, Darryl B. McConnell, Dirk Kessler, Robert Konrat, Moriz Mayer

المصدر: Journal of Medicinal Chemistry. 60:8708-8715

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Drug, Stereochemistry, media_common.quotation_subject, Cell Cycle Proteins, Plasma protein binding, Ligands, 01 natural sciences, 03 medical and health sciences, Low affinity, Drug Discovery, Humans, Binding site, Cell Cycle Protein, Nuclear Magnetic Resonance, Biomolecular, media_common, Binding Sites, 010405 organic chemistry, Chemistry, Ligand, Titrimetry, Nuclear Proteins, Proteins, Water, Combinatorial chemistry, 0104 chemical sciences, Bromodomain, 030104 developmental biology, Drug Design, Molecular Medicine, Protein Binding, Transcription Factors, Protein ligand

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bb2b2299cd1e3e722c6fdf9517ce2a
https://doi.org/10.1021/acs.jmedchem.7b00845

المؤلفون: Gabriella Siszler, Andreas Bergner, Barbara Müllauer, Andreas Mantoulidis, Laetitia J. Martin, Andreas Gollner, Darryl B. McConnell, Bernhard Wolkerstorfer, Xiao-Ling Cockcroft, Moriz Mayer, Dirk Kessler, Wolfgang Hela, Gerhard Fischer, Roland Kousek

المصدر: Chemistry (Weinheim an Der Bergstrasse, Germany)

مصطلحات موضوعية: natural products, Computational biology, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Catalysis, chemistry.chemical_compound, NMR spectroscopy, Drug Discovery, medicine, KRAS, X-ray crystallography, Virtual screening, Natural product, 010405 organic chemistry, Drug discovery, Communication, Organic Chemistry, General Chemistry, Integrated approach, virtual screening, Communications, 0104 chemical sciences, chemistry, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76863501a4fb5d279835adefcd8a8f8
https://pubmed.ncbi.nlm.nih.gov/31231840

المؤلفون: Andreas Gollner, Dirk Kessler, Andreas Mantoulidis, Darryl B. McConnell, Bernhard Wolkerstorfer, Gabriella Siszler, Barbara Müllauer, Andreas Bergner, Roland Kousek, Wolfgang Hela, Laetitia J. Martin, Moriz Mayer, Gerhard Fischer, Xiao-Ling Cockcroft

المصدر: Chemistry – A European Journal. 25:11998-11998

مصطلحات موضوعية: Crystallography, Front cover, Chemistry, Organic Chemistry, medicine, General Chemistry, Nuclear magnetic resonance spectroscopy, KRAS, medicine.disease_cause, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0442b83d758074e821c739a5fad0548a
https://doi.org/10.1002/chem.201903597

المؤلفون: Geist, Leonhard, Mayer, Moriz, Xiao-Ling Cockcroft, Wolkerstorfer, Bernhard, Kessler, Dirk, Engelhardt, Harald, McConnell, Darryl B., Konrat, Robert

المصدر: Journal of Medicinal Chemistry; 11/9/2017, Vol. 60 Issue 21, p8708-8715, 8p

المؤلفون: Keith A. Menear, Niall M. B. Martin, Claire Adcock, Robert Boulter, Xiao-ling Cockcroft, Louise Copsey, Aaron Cranston, Krystyna J. Dillon, Jan Drzewiecki, Sheila Garman, Sylvie Gomez, Hashim Javaid, Frank Kerrigan, Charlotte Knights, Alan Lau, Vincent M. Loh Jr., Ian T. W. Matthews, Stephen Moore, Mark J. O’Connor, Graeme C. M. Smith

المصدر: Journal of Medicinal Chemistry; Oct2008, Vol. 51 Issue 20, p6581-6591, 11p