يعرض 1 - 18 نتائج من 18 نتيجة بحث عن '"XBD173"', وقت الاستعلام: 0.51s تنقيح النتائج
  1. 1
    Academic Journal
    Assessment of the concomitant action of XBD173 and interferon β in a mouse model of multiple sclerosis using infrared marker bands

    المؤلفون: Sirinukunwattana, Krongkarn, Klein, Christian, Clarke, Paul, F A, Marcou, Gilles, Meyer, Laurence, Collongues, Nicolas, de Sèze, Jérôme, Hellwig, Petra, Patte-Mensah, Christine, El Khoury, Youssef, Mensah-Nyagan, Ayikoé-Guy

    المساهمون: Chimie de la matière complexe (CMC), Université de Strasbourg (UNISTRA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques (BMNST), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), CIC Strasbourg (Centre d’Investigation Clinique Plurithématique (CIC - P)), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nouvel Hôpital Civil de Strasbourg, Les Hôpitaux Universitaires de Strasbourg (HUS)-Les Hôpitaux Universitaires de Strasbourg (HUS)-Hôpital de Hautepierre Strasbourg, ANR-10-IDEX-0002,UNISTRA,Par-delà les frontières, l'Université de Strasbourg(2010)

    المصدر: ISSN: 1386-1425 ; EISSN: 1873-3557.

    مصطلحات موضوعية: Animal model, Infrared spectroscopy, Interferon-β, Multiple sclerosis, XBD173, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

    Relation: info:eu-repo/semantics/altIdentifier/pmid/39515236; PUBMED: 39515236

    الاتاحة: https://hal.science/hal-04893349
    https://hal.science/hal-04893349v1/document
    https://hal.science/hal-04893349v1/file/1-s2.0-S1386142524015567-main.pdf
    https://doi.org/10.1016/j.saa.2024.125390

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  2. 2
    Academic Journal
    Neurosteroids Mediate Neuroprotection in an In Vitro Model of Hypoxic/Hypoglycaemic Excitotoxicity via δ-GABAA Receptors without Affecting Synaptic Plasticity

    المؤلفون: Xènia Puig-Bosch, Markus Ballmann, Stefan Bieletzki, Bernd Antkowiak, Uwe Rudolph, Hanns Ulrich Zeilhofer, Gerhard Rammes

    المصدر: International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 9056

    مصطلحات موضوعية: excitotoxicity, GABA A receptors, hippocampus, LTP, neuroprotection, neurosteroids, TSPO, XBD173

    جغرافية الموضوع: agris

    وصف الملف: application/pdf

    Relation: Molecular Neurobiology; https://dx.doi.org/10.3390/ijms24109056

    الاتاحة: https://doi.org/10.3390/ijms24109056

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  3. 3
    Academic Journal
    Neurosteroids Mediate Neuroprotection in an In Vitro Model of Hypoxic/Hypoglycaemic Excitotoxicity via δ-GABA A Receptors without Affecting Synaptic Plasticity

    المؤلفون: Puig-Bosch, Xènia, Ballmann, Markus, Bieletzki, Stefan, Antkowiak, Bernd, Rudolph, Uwe, Zeilhofer, Hanns U., id_orcid:0 000-0001-6954-4629, Rammes, Gerhard

    المصدر: International Journal of Molecular Sciences, 24 (10)

    مصطلحات موضوعية: excitotoxicity, GABA A receptors, hippocampus, LTP, neuroprotection, neurosteroids, TSPO, XBD173

    وصف الملف: application/application/pdf

    Relation: info:eu-repo/semantics/altIdentifier/wos/000997370000001; http://hdl.handle.net/20.500.11850/615087

    الاتاحة: https://hdl.handle.net/20.500.11850/615087
    https://doi.org/10.3929/ethz-b-000615087

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  4. 4
    Investigação de novos fármacos ansiolíticos que atuam na proteína translocadora 18 KDa (TSPO)

    المؤلفون: Pereira, Natália Cristina Ferraz da Silva

    المساهمون: Capela, João Paulo Soares, Repositório Institucional da Universidade Fernando Pessoa

    مصطلحات موضوعية: Ansiedade, Proteína Translocadora (18 KDa) (TSPO), Etifoxina, XBD173, YL‑IPA08, Anxiety, Translocator Protein (18 KDa) (TSPO), Domínio/Área Científica::Ciências Médicas::Medicina Básica

    وصف الملف: application/pdf

    الاتاحة: http://hdl.handle.net/10284/10467

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  5. 5
    Academic Journal
    Human pharmacokinetics of XBD173 and etifoxine distinguish their potential for pharmacodynamic effects mediated by TSPO

    المؤلفون: Owen, D

    المساهمون: Medical Research Council (MRC), National Institute for Health Research, UK DRI Ltd

    المصدر: 4236 ; 4230

    مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Pharmacology & Pharmacy, anti-inflammatory drugs, brain, etifoxine, translocator protein, XBD173, PERIPHERAL BENZODIAZEPINE-RECEPTOR, TSPO LIGAND ETIFOXINE, TUMOR-NECROSIS-FACTOR, ANXIOLYTIC ETIFOXINE, MOUSE MODEL, MICROGLIAL ACTIVATION, IN-VIVO, 18 KDA, 1115 Pharmacology and Pharmaceutical Sciences

    Relation: British Journal of Clinical Pharmacology; http://hdl.handle.net/10044/1/97016; MR/N026934/1; RDA26; DRI-CORE2020-IMP; N/A

    الاتاحة: http://hdl.handle.net/10044/1/97016
    https://doi.org/10.1111/bcp.15392

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  6. 6
    Academic Journal
    Confirmation of specific binding of the 18 kDa translocator protein (TSPO) radioligand [18F]GE-180: a blocking study using XBD173 in multiple sclerosis normal appearing white and grey matter

    المؤلفون: Sridharan, S, Raffel, J, Nandoskar, A, Record, C, Brooks, DJ, Owen, D, Sharp, D, Muraro, PA, Gunn, R, Nicholas, R

    المساهمون: Medical Research Council (MRC), Imperial College Healthcare NHS Trust- BRC Funding, Alzheimer's Research UK (ARUK), National Institute for Health Research

    المصدر: 944 ; 935

    مصطلحات موضوعية: Multiple sclerosis, Occupancy plot, PET, Polymorphism plot, XBD173, [11C]PBR28, [18F]GE-180, 1103 Clinical Sciences, 0606 Physiology, Nuclear Medicine & Medical Imaging

    Relation: Molecular Imaging and Biology; http://hdl.handle.net/10044/1/66971; https://doi.org/10.1007/s11307-019-01323-8; MR/N008219/1; RDA03 79560; ART/PG2005/3; NIHR-RP-011-048

    الاتاحة: http://hdl.handle.net/10044/1/66971
    https://doi.org/10.1007/s11307-019-01323-8

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  7. 7
    Synergistic Interactions between Endogenous Neurosteroids and Zolpidem in Cultured Neocortical Tissue Slices

    المؤلفون: Gotthard, Clara Simone

    المساهمون: Antkowiak, Bernd (Prof. Dr.)

    مصطلحات موضوعية: Zolpidem, GABA(A) receptor, Neurosteroids, GABA(A)-Rezeptor, Neurosteroide, XBD173

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb518d58ff18a826fce7aca404d4abe4
    https://hdl.handle.net/10900/132432

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  8. 8
    Specific and non-specific binding of a tracer for the translocator-specific protein in schizophrenia: an [11C]-PBR28 blocking study

    المؤلفون: Tiago Reis Marques, David R. Owen, Oliver D. Howes, Mattia Veronese, Graham E. Searle, Eugenii A. Rabiner

    المصدر: European Journal of Nuclear Medicine and Molecular Imaging

    مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Population, 03 medical and health sciences, 0302 clinical medicine, Receptors, GABA, Internal medicine, medicine, Translocator protein, Radioligand, Humans, Radiology, Nuclear Medicine and imaging, Carbon Radioisotopes, 11c pbr28, education, education.field_of_study, biology, medicine.diagnostic_test, business.industry, Brain, General Medicine, Ligand (biochemistry), medicine.disease, 030104 developmental biology, Endocrinology, Schizophrenia, Positron emission tomography, Positron-Emission Tomography, biology.protein, Original Article, Microglia, Tomography, X-Ray Computed, business, TSPO, 030217 neurology & neurosurgery, XBD173, Protein Binding, Diagnosis of schizophrenia

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4025751002fca716e364cdb7ce55bc2f
    https://doi.org/10.1007/s00259-021-05327-x

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  9. 9
    Academic Journal
    Kinetic modelling of [11C]PBR28 for 18 kDa translocator protein PET data: A validation study of vascular modelling in the brain using XBD173 and tissue analysis

    المؤلفون: Veronese, Mattia, Reis Marques, Tiago, Bloomfeld, Peter S, Rizzo, Gaia, Singh, Nisha, Jones, Deborah, Agushi, Erjon, Mosses, Dominic, Bertoldo, Allessandra, Howes, Oliver, Roncaroli, Federico, Turkheimer, Frederico F

    المصدر: Journal of Cerebral Blood Flow and Metabolism, (2017-06-05)

    مصطلحات موضوعية: 3D modelling, TSPO, XBD173, [11C]PBR28, endothelium, immunohistochemistry, kinetic modelling

    Relation: https://zenodo.org/communities/inmind; https://zenodo.org/communities/eu; https://doi.org/10.1177/0271678X17712388; oai:zenodo.org:906142

    الاتاحة: https://doi.org/10.1177/0271678X17712388

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  10. 10
    Academic Journal
    11C-ER176, a radioligand for 18-kDa translocator protein (TSPO), has adequate sensitivity to robustly image all three affinity genotypes in human brain

    المؤلفون: Ikawa, Masamichi, Lohith, Talakad G, Shrestha, Stal, Telu, Sanjay, Zoghbi, Sami S, CASTELLANO, Sabrina, Taliani, Sabrina, Da Settimo, Federico, Fujita, Masahiro, Pike, Victor W, Innis, Robert B.

    المساهمون: Ikawa, Masamichi, Lohith, Talakad G, Shrestha, Stal, Telu, Sanjay, Zoghbi, Sami S, Castellano, Sabrina, Taliani, Sabrina, Da Settimo, Federico, Fujita, Masahiro, Pike, Victor W, Innis, Robert B.

    مصطلحات موضوعية: 18-kDa translocator protein (TSPO), 11C-ER176, Neurology, PET, Radiopharmaceutical, XBD173, positron emission tomography, rs6971 polymorphism

    Relation: info:eu-repo/semantics/altIdentifier/pmid/27856631; info:eu-repo/semantics/altIdentifier/wos/WOS:000393360100028; volume:58; firstpage:320; lastpage:325; numberofpages:6; journal:THE JOURNAL OF NUCLEAR MEDICINE; http://hdl.handle.net/11386/4676450; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85012016369; http://dx.doi.org/10.2967/jnumed.116.178996

    الاتاحة: http://hdl.handle.net/11386/4676450
    https://doi.org/10.2967/jnumed.116.178996

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  11. 11
    11C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than 11C-(R)-PK11195

    المؤلفون: Robert B. Innis, Sami S. Zoghbi, David R. Owen, Victor W. Pike, Roger N. Gunn, Teresa Jiang, Eugenii A. Rabiner, Qi Guo, Masahiro Fujita, Masato Kobayashi, Sanjay Telu

    المساهمون: Medical Research Council (MRC)

    المصدر: Journal of Cerebral Blood Flow & Metabolism. 38:393-403

    مصطلحات موضوعية: Pathology, medicine.medical_specialty, metabolite-corrected arterial input, positron emission tomography, Pharmacology, 1102 Cardiovascular Medicine And Haematology, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, DPA-713, 0302 clinical medicine, Translocator protein, Medicine, Neuroinflammation, Neurology & Neurosurgery, biology, medicine.diagnostic_test, business.industry, 18 kDa (TSPO), 1103 Clinical Sciences, Original Articles, Human brain, medicine.anatomical_structure, Neurology, Positron emission tomography, biology.protein, Neurology (clinical), rs6971 polymorphism, 1109 Neurosciences, Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery, XBD173

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028354559392a79a362bf1252af6232f
    https://doi.org/10.1177/0271678x17699223

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  12. 12
    Academic Journal
    Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [ 18 F]GE-180:a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter

    المؤلفون: Sridharan, S., Raffel, J., Nandoskar, A., Record, C., Brooks, D., Owen, D., Sharp, D., Muraro, P., Gunn, R., Nicholas, R.

    المصدر: Sridharan , S , Raffel , J , Nandoskar , A , Record , C , Brooks , D , Owen , D , Sharp , D , Muraro , P , Gunn , R & Nicholas , R 2019 , ' Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [ 18 F]GE-180 : a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter ' , Multiple Sclerosis Journal , vol. 21 , no. 5 , pp. 935-944 . https://doi.org/10.1007/s11307-019-01323-8

    مصطلحات موضوعية: Multiple sclerosis, Occupancy plot, PET, Polymorphism plot, XBD173, [ C]PBR28, [ F]GE-180, envir, socio

    Relation: https://pure.au.dk/ws/files/162833436/Sridharan_CTS_MIBI_D_18_00260.pdf; https://pure.au.dk/portal/da/publications/confirmation-of-specific-binding-of-the-18kda-translocator-protein-tspo-radioligand--18fge180(42be0847-b2ee-4993-86b7-fc7ad8426675).html

    الاتاحة: https://pure.au.dk/ws/files/162833436/Sridharan_CTS_MIBI_D_18_00260.pdf
    https://pure.au.dk/portal/da/publications/confirmation-of-specific-binding-of-the-18kda-translocator-protein-tspo-radioligand--18fge180(42be0847-b2ee-4993-86b7-fc7ad8426675).html

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  13. 13
    Dissertation/ Thesis
    Neuroprotection dans des modèles animaux de la sclérose en plaques : évaluation pluridisciplinaire de la capacité du XBD173, un ligand du translocator protein, à améliorer les symptômes cliniques et les marqueurs neuropathologiques
    Neuroprotection in animal models of multiple sclerosis : a multidisciplinary evaluation of the ability of XBD173, a translocator protein ligand, to improve the clinical symptoms and neuropathological markers

    المؤلفون: Leva, Géraldine

    Thesis Advisors: Strasbourg, Patte-Mensah, Christine

    مصطلحات موضوعية: Ligand du translocator protein, Neuroprotection, Neurostéroïdes, Sclérose en plaques, Stratégie thérapeutique, TSPO, XBD173, Emapunil, Ligand of translocator protein, Multiple sclerosis, Neurosteroids, Therapeutic strategy, 572.8, 616.83

    الاتاحة: http://www.theses.fr/2017STRAJ076/document

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  14. 14
    Academic Journal
    (11)C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than (11)C-( R)-PK11195

    المؤلفون: Kobayashi, M, Jiang, T, Telu, S, Zoghbi, SS, Gunn, RN, Rabiner, EA, Owen, DR, Guo, Q, Pike, VW, Innis, RB, Fujita, M

    المساهمون: Medical Research Council (MRC)

    المصدر: 403 ; 393

    مصطلحات موضوعية: 18 kDa (TSPO), XBD173, metabolite-corrected arterial input, positron emission tomography, rs6971 polymorphism, 1103 Clinical Sciences, 1109 Neurosciences, 1102 Cardiovascular Medicine And Haematology, Neurology & Neurosurgery

    Relation: Journal of Cerebral Blood Flow and Metabolism; http://hdl.handle.net/10044/1/51601; https://dx.doi.org/10.1177/0271678X17699223; MR/N008219/1; MR/N026934/1

    الاتاحة: http://hdl.handle.net/10044/1/51601
    https://doi.org/10.1177/0271678X17699223

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  15. 15
    Neuroprotection in animal models of multiple sclerosis : a multidisciplinary evaluation of the ability of XBD173, a translocator protein ligand, to improve the clinical symptoms and neuropathological markers

    المؤلفون: Leva, Géraldine

    المساهمون: STAR, ABES, Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques (BMNST), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Strasbourg, Christine Patte-Mensah

    المصدر: Neurobiologie. Université de Strasbourg, 2017. Français. ⟨NNT : 2017STRAJ076⟩

    مصطلحات موضوعية: [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Ligand of translocator protein, Neurostéroïdes, Emapunil, Neuroprotection, Sclérose en plaques, nervous system diseases, Multiple sclerosis, immune system diseases, [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Therapeutic strategy, Ligand du translocator protein, Neurosteroids, Stratégie thérapeutique, TSPO, XBD173

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1398::391943c546bc3ef1dae916e9083dce3b
    https://theses.hal.science/tel-01744411

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  16. 16
    11C-ER176, a radioligand for 18-kDa translocator protein (TSPO), has adequate sensitivity to robustly image all three affinity genotypes in human brain

    المؤلفون: Federico Da Settimo, Talakad G. Lohith, Victor W. Pike, Sabrina Taliani, Sabrina Castellano, Stal Shrestha, Sanjay Telu, Sami S. Zoghbi, Masamichi Ikawa, Masahiro Fujita, Robert B. Innis

    مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, PK-11195, positron emission tomography, Genotype, 18-kDa translocator protein (TSPO), 11C-ER176, Neurology, PET, Radiopharmaceuticals, XBD173, rs6971 polymorphism, Pharmacology, Sensitivity and Specificity, 030218 nuclear medicine & medical imaging, Diagnosis, Differential, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Positron emission tomography, Rs6971 polymorphism, Radiology, Nuclear Medicine and Imaging, Neuroimaging, Receptors, GABA, In vivo, Nuclear Medicine and Imaging, medicine, Translocator protein, Radioligand, Humans, Radiology, Nuclear Medicine and imaging, Carbon Radioisotopes, Observer Variation, biology, medicine.diagnostic_test, Chemistry, Binding potential, Brain, Reproducibility of Results, Human brain, Molecular Imaging, medicine.anatomical_structure, biology.protein, Female, Radiology, 030217 neurology & neurosurgery

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf556c2c2f55a72d4d722b1a185866f4
    http://hdl.handle.net/11386/4676450

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  17. 17
    Dissertation/ Thesis
    Neuroprotection dans des modèles animaux de la sclérose en plaques : évaluation pluridisciplinaire de la capacité du XBD173, un ligand du translocator protein, à améliorer les symptômes cliniques et les marqueurs neuropathologiques ; Neuroprotection in animal models of multiple sclerosis : a multidisciplinary evaluation of the ability of XBD173, a translocator protein ligand, to improve the clinical symptoms and neuropathological markers

    المؤلفون: Leva, Géraldine

    المساهمون: Strasbourg, Patte-Mensah, Christine

    مصطلحات موضوعية: Ligand du translocator protein, Neuroprotection, Neurostéroïdes, Sclérose en plaques, Stratégie thérapeutique, TSPO, XBD173, Emapunil, Ligand of translocator protein, Multiple sclerosis, Neurosteroids, Therapeutic strategy, 572.8, 616.83

    Relation: http://www.theses.fr/2017STRAJ076/document

    الاتاحة: http://www.theses.fr/2017STRAJ076/document

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  18. 18
    Dissertation/ Thesis
    Neuroprotection in animal models of multiple sclerosis : a multidisciplinary evaluation of the ability of XBD173, a translocator protein ligand, to improve the clinical symptoms and neuropathological markers ; Neuroprotection dans des modèles animaux de la sclérose en plaques : évaluation pluridisciplinaire de la capacité du XBD173, un ligand du translocator protein, à améliorer les symptômes cliniques et les marqueurs neuropathologiques

    المؤلفون: Leva, Géraldine

    المساهمون: Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques (BMNST), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Strasbourg, Christine Patte-Mensah

    المصدر: https://theses.hal.science/tel-01744411 ; Neurobiologie. Université de Strasbourg, 2017. Français. ⟨NNT : 2017STRAJ076⟩.

    مصطلحات موضوعية: Ligand of translocator protein, Multiple sclerosis, Neuroprotection, Neurosteroids, Therapeutic strategy, TSPO, XBD173, Emapunil, Ligand du translocator protein, Neurostéroïdes, Sclérose en plaques, Stratégie thérapeutique, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology

    Relation: NNT: 2017STRAJ076; tel-01744411; https://theses.hal.science/tel-01744411; https://theses.hal.science/tel-01744411/document; https://theses.hal.science/tel-01744411/file/LEVA_Geraldine_2017_ED414.pdf

    الاتاحة: https://theses.hal.science/tel-01744411
    https://theses.hal.science/tel-01744411/document
    https://theses.hal.science/tel-01744411/file/LEVA_Geraldine_2017_ED414.pdf

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