المؤلفون: Rashid, Ishtiaque, Hammel, Michal, Sverzhinsky, Aleksandr, Tsai, Miaw-Sheue, Pascal, John M, Tainer, John A, Tomkinson, Alan E

المصدر: Journal of Biological Chemistry. 297(2)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Cancer, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Phosphoric Diester Hydrolases, DNA Ligase ATP, Phosphorylation, Humans, DNA Repair, Catalytic Domain, X-ray Repair Cross Complementing Protein 1, Animals, DNA-Binding Proteins, Mice, DNA Breaks, Single-Stranded, Protein Binding, DNA ligation, electron microscopy, phosphorylation, protein structure, small angle x-ray scattering, topoisomerase, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2409f20f
https://escholarship.org/content/qt2409f20f/qt2409f20f.pdf

المؤلفون: Sito, Hilary, Sharzehan, Mohamad Ayub Khan, Islam, Md Asiful, Tan, Shing Cheng

المساهمون: University of Birmingham, UKM Medical Molecular Biology Institute, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

المصدر: 81 ; 11835

مصطلحات موضوعية: platinum-based chemotherapy, non-small cell lung cancer, polymorphisms, systematic review, Animals, Humans, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Cytochrome P-450 CYP1A1, Computational Biology, Genotype, Xeroderma Pigmentosum Group D Protein, X-ray Repair Cross Complementing Protein 1

وصف الملف: application/pdf

Relation: https://www.frontierspartnerships.org/journals/british-journal-of-biomedical-science/articles/10.3389/bjbs.2024.11835/full; 38450253 (pubmed); http://hdl.handle.net/2436/625656; British Journal of Biomedical Science

الاتاحة: http://hdl.handle.net/2436/625656
https://doi.org/10.3389/bjbs.2024.11835

المؤلفون: Serrano-Benitez, Almudena, Wells, Sophie E, Drummond-Clarke, Lylah, Russo, Lilian C, Thomas, John Christopher, Leal, Giovanna A, Farrow, Mark, Edgerton, James Michael, Balasubramanian, Shankar, Yang, Ming, Frezza, Christian, Gautam, Amit, Brazina, Jan, Burdova, Kamila, Hoch, Nicolas C, Jackson, Stephen P, Caldecott, Keith W

مصطلحات موضوعية: DNA repair, DNA replication stress, DNA strand breaks, PARP-1, genome instability, Humans, Poly(ADP-ribose) Polymerase Inhibitors, DNA-Binding Proteins, Chromosome Breakage, DNA Replication, DNA, Antineoplastic Agents, X-ray Repair Cross Complementing Protein 1

وصف الملف: application/pdf; application/zip; text/xml

Relation: https://www.repository.cam.ac.uk/handle/1810/375530

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/375530

المؤلفون: Hammel, Michal, Rashid, Ishtiaque, Sverzhinsky, Aleksandr, Pourfarjam, Yasin, Tsai, Miaw-Sheue, Ellenberger, Tom, Pascal, John M, Kim, In-Kwon, Tainer, John A, Tomkinson, Alan E

المصدر: Nucleic Acids Research. 49(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cancer, Genetics, 1.1 Normal biological development and functioning, Generic health relevance, Chromatography, Gel, Crystallography, X-Ray, DNA Ligase ATP, DNA Repair, Dimerization, Humans, Microscopy, Electron, Models, Molecular, Multiprotein Complexes, Mutation, Mutation, Missense, Negative Staining, Point Mutation, Protein Conformation, Protein Domains, Protein Interaction Mapping, Recombinant Proteins, Scattering, Small Angle, X-ray Repair Cross Complementing Protein 1, Environmental Sciences, Information and Computing Sciences, Developmental Biology, Biological sciences, Chemical sciences, Environmental sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9q41p570
https://escholarship.org/content/qt9q41p570/qt9q41p570.pdf

المؤلفون: Khadijeh Najafi-Ghobadi, Mahdieh Rajabi-Moghaddam, Hamid Abbaszadeh

المصدر: Heliyon, Vol 9, Iss 10, Pp e21111- (2023)

مصطلحات موضوعية: Genetic polymorphism, X-ray repair cross complementing protein 1, Prognosis, Squamous cell carcinoma of head and neck, Science (General), Q1-390, Social sciences (General), H1-99

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844023083196; https://doaj.org/toc/2405-8440

URL الوصول: https://doaj.org/article/11a235b705e04d56aa2000d8244b25d0

المؤلفون: Nooshin Mohtasham, Khadijeh Najafi‐Ghobadi, Hamid Abbaszadeh

المصدر: Cancer Reports, Vol 6, Iss 3, Pp n/a-n/a (2023)

مصطلحات موضوعية: genetic polymorphism, squamous cell carcinoma of head and neck, X‐ray repair cross complementing protein 1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2573-8348

URL الوصول: https://doaj.org/article/cc6db8250f70463aa82433e8fffee549

المؤلفون: Serrano-Benitez, Almudena, Wells, Sophie E, Drummond-Clarke, Lylah, Russo, Lilian C, Thomas, John Christopher, Leal, Giovanna A, Farrow, Mark, Edgerton, James Michael, Balasubramanian, Shankar, Yang, Ming, Frezza, Christian, Gautam, Amit, Brazina, Jan, Burdova, Kamila, Hoch, Nicolas C, Jackson, Stephen P, Caldecott, Keith W

مصطلحات موضوعية: DNA repair, DNA replication stress, DNA strand breaks, PARP-1, genome instability, Humans, Poly(ADP-ribose) Polymerase Inhibitors, DNA-Binding Proteins, Chromosome Breakage, DNA Replication, DNA, Antineoplastic Agents, X-ray Repair Cross Complementing Protein 1

وصف الملف: application/pdf; text/xml

Relation: https://www.repository.cam.ac.uk/handle/1810/355299

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/355299

المؤلفون: Diaz-Perez, Silvia, Kane, Nathanael, Kurmis, Alexis A, Yang, Fei, Kummer, Nicolas T, Dervan, Peter B, Nickols, Nicholas G

المصدر: PloS one. 13(5)

مصطلحات موضوعية: Cell Line, Tumor, Humans, DNA Damage, Imidazoles, Pyrroles, Nylons, DNA, DNA Repair, Radiation, Ionizing, Small Molecule Libraries, DNA Ligase ATP, X-ray Repair Cross Complementing Protein 1, Cell Line, Tumor, Radiation, Ionizing, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1d57c8qn

المؤلفون: Dutta, Arijit, Eckelmann, Bradley, Adhikari, Sanjay, Ahmed, Kazi Mokim, Sengupta, Shiladitya, Pandey, Arvind, Hegde, Pavana M, Tsai, Miaw-Sheue, Tainer, John A, Weinfeld, Michael, Hegde, Muralidhar L, Mitra, Sankar

المصدر: Nucleic Acids Research. 45(5)

مصطلحات موضوعية: Cancer, Genetics, 2.1 Biological and endogenous factors, Aetiology, Casein Kinase II, Cell Line, Tumor, DNA Breaks, Double-Stranded, DNA End-Joining Repair, DNA-Binding Proteins, Humans, Phosphorylation, X-Rays, X-ray Repair Cross Complementing Protein 1, Environmental Sciences, Biological Sciences, Information and Computing Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/73x0p05b

المساهمون: Ji-Ye Kim, Entaz Bahar, Jung-Yun Lee, Sunhee Chang, Se Hoon Kim, Eun Young Park, Sung-Im Do, Hyonok Yoon, Hyun-Soo Kim, Kim, Se Hoon

مصطلحات موضوعية: Antineoplastic Agents* / pharmacology, Antineoplastic Agents* / therapeutic use, Apoptosis, Carcinoma* / genetics, Carcinoma, Ovarian Epithelial / genetics, Cell Line, Tumor, Cisplatin / metabolism, Cisplatin / pharmacology, Cisplatin / therapeutic use, DNA Repair, Drug Resistance, Neoplasm / genetics, Female, Gene Expression Regulation, Neoplastic, Heat-Shock Proteins / metabolism, Humans, Membrane Transport Proteins / metabolism, Ovarian Neoplasms* / drug therapy, Ovarian Neoplasms* / genetics, Ovarian Neoplasms* / pathology, X-ray Repair Cross Complementing Protein 1 / genetics

Relation: CELL DEATH & DISEASE; J00482; OAK-2022-01802; https://ir.ymlib.yonsei.ac.kr/handle/22282913/188826; T202201573; CELL DEATH & DISEASE, Vol.13(3) : 239, 2022-03

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/188826
https://doi.org/10.1038/s41419-022-04568-4

المؤلفون: Peña-Gómez, María José, Suárez-Pizarro, Marina, Rosado, Iván V

مصطلحات موضوعية: 5hmU-mediated genomic instability, XRCC1, epigenetic DNA bases, replication fork instability by 5hmC, 5-Methylcytosine, Cell Line, Cell Survival, DNA Damage, DNA Demethylation, DNA Replication, Deoxycytidine, Epigenesis, Genetic, Genomic Instability, Humans, Replication Origin, Thymidine, X-ray Repair Cross Complementing Protein 1

وصف الملف: application/pdf

Relation: http://hdl.handle.net/10668/21132; PMC8779622; https://www.mdpi.com/1422-0067/23/2/893/pdf?version=1644293040; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779622/pdf

الاتاحة: http://hdl.handle.net/10668/21132
https://doi.org/10.3390/ijms23020893
https://www.mdpi.com/1422-0067/23/2/893/pdf?version=1644293040
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779622/pdf

المؤلفون: Rashid, Ishtiaque, Tsai, Miaw-Sheue, Sverzhinsky, Aleksandr, Hlaing, Aye Su, Shih, Brian, Thwin, Aye C, Lin, Judy G, Maw, Su S, Pascal, John M, Tomkinson, Alan E

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Biotechnology, Genetics, Underpinning research, 1.1 Normal biological development and functioning, Generic health relevance, Animals, DNA Ligase ATP, DNA Ligases, DNA-Binding Proteins, Humans, Insecta, Poly-ADP-Ribose Binding Proteins, X-ray Repair Cross Complementing Protein 1, Xenopus Proteins, Affinity chromatography, Bacmid, Baculovirus, Insect cells, Ion exchange chromatography, Multiple angle light scattering, Negative stain electron microscopy, Size exclusion chromatography, Other Chemical Sciences, Developmental Biology, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

Relation: qt2f81b4nf; https://escholarship.org/uc/item/2f81b4nf

الاتاحة: https://escholarship.org/uc/item/2f81b4nf

المؤلفون: Iyama, Teruaki, Wilson, David M

المصدر: DNA Repair. 12(8)

مصطلحات موضوعية: Genetics, Stem Cell Research, Stem Cell Research - Nonembryonic - Human, Cancer, Neurosciences, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Aetiology, Underpinning research, Generic health relevance, Neurological, Animals, DNA, DNA Damage, DNA Repair, Disease Models, Animal, Humans, Neurons, O(6)-Methylguanine-DNA Methyltransferase, Pyrimidine Dimers, 6-4PPs, 8-oxoguanine DNA glycosylase, AOA1, AP, AP endonuclease 1, APE1, APTX, ATM, CPDs, CS, CSR, Cockayne syndrome, DAR, DNA double strand break repair, DNA polymerase β, DNA repair, DNA single strand break repair, DNA single strand breaks, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, DSBR, Dividing and non-dividing, ERCC1, Endogenous DNA damage, FEN1, GG-NER, HNPCC, HR, IR, MAP, MCSZ, MGMT, MMR, MPG, MUTYH, MUTYH-associated polyposis, N-methylpurine-DNA glycosylase, NEIL1, NER, NHEJ, NSC, NTH1, Neural cells, Neurological disorder, O(6)-methylguanine-DNA methyltransferase, OGG1, PARP1, PCNA, PG, PNKP, PUA, Pol β, RFC, RNA polymerase, RNAP, RPA, SCAN1, SCID, SDSA, SSA, SSBR, SSBs, TC-NER, TDP1, TFIIH, TOP1, TTD, Top1 cleavage complex, Top1cc, UNG, X-ray repair cross-complementing protein 1, XP, XRCC1, aprataxin, apurinic/apyrimidinic, ataxia telangiectasia mutated, ataxia with ocular motor apraxia 1, class switch recombination, cyclobutane pyrimidine dimers, dRP, deoxyribose-5-phosphate, endonuclease III-like 1, endonuclease VIII-like 1, excision repair cross complementing 1, flap endonuclease 1, global genome-NER, hereditary nonpolyposis colorectal cancer, homologous recombination, human mutY homolog, ionizing radiation, microcephaly with early-onset, intractable seizures and developmental delay, mismatch repair, neural stem cells, nonhomologous end joining, nucleotide excision repair, phospho-α, β-unsaturated aldehyde, phosphoglycolate, poly(ADP-ribose) polymerase-1, polynucleotide kinase 3′-phosphatase, proliferating cellular nuclear antigen, pyrimidine-(6, 4)-pyrimidone photoproducts., replication factor C, replication protein A, severe combined immunodeficient, single-strand annealing, spinocerebellar ataxia with axonal neuropathy-1, synthesis-dependent strand annealing, topoisomerase 1, transcription domains-associated repair, transcription factor II H, transcription-coupled NER, trichothiodystrophy, tyrosyl-DNA phosphodiesterase 1, uracil-DNA glycosylase, xeroderma pigmentosum, Biochemistry and Cell Biology, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/33c5w49n

المساهمون: Entaz Bahar, Ji-Ye Kim, Hyun-Soo Kim, Hyonok Yoon

مصطلحات موضوعية: Antineoplastic Agents / toxicity, Cadherins / genetics, Cadherins / metabolism, Cell Death, Cell Line, Tumor, Cisplatin / toxicity, DNA Repair, Drug Resistance, Neoplasm, Epithelial-Mesenchymal Transition, Female, Humans, Inhibitory Concentration 50, Nuclear Proteins / genetics, Nuclear Proteins / metabolism, Ovarian Neoplasms / genetics, Ovarian Neoplasms / metabolism, Poly (ADP-Ribose) Polymerase-1 / genetics, Poly (ADP-Ribose) Polymerase-1 / metabolism, Twist-Related Protein 1 / genetics, Twist-Related Protein 1 / metabolism, Vimentin / genetics, Vimentin / metabolism, X-ray Repair Cross Complementing Protein 1 / genetics, X-ray Repair Cross Complementing Protein 1 / metabolism, ovarian cancer, cisplatin resistance, Twist, metastasis

Relation: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; J01133; OAK-2022-03545; https://ir.ymlib.yonsei.ac.kr/handle/22282913/189958; T9992020179; INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.21(20) : 7613, 2020-10

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/189958
https://doi.org/10.3390/ijms21207613

المؤلفون: Della-Maria, Julie, Hegde, Muralidhar L, McNeill, Daniel R, Matsumoto, Yoshihiro, Tsai, Miaw-Sheue, Ellenberger, Tom, Wilson, David M, Mitra, Sankar, Tomkinson, Alan E

المصدر: Journal of Biological Chemistry. 287(46)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Aetiology, Underpinning research, Generic health relevance, Cell Survival, DNA Damage, DNA Ligases, DNA Repair, DNA Repair Enzymes, DNA-Binding Proteins, Gene Expression Regulation, Humans, Kinetics, Microscopy, Confocal, Mutation, Nuclear Proteins, Phosphotransferases (Alcohol Group Acceptor), Protein Binding, Protein Interaction Mapping, Protein Structure, Tertiary, Threonine, Two-Hybrid System Techniques, X-ray Repair Cross Complementing Protein 1, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/142812t5
https://escholarship.org/content/qt142812t5/qt142812t5.pdf

المؤلفون: Karahalil, B, Bohr, VA, Wilson, DM

المصدر: Human & Experimental Toxicology. 31(10)

مصطلحات موضوعية: Colo-Rectal Cancer, Cancer, Genetic Testing, Genetics, Human Genome, Digestive Diseases, Prevention, Aetiology, 2.1 Biological and endogenous factors, Animals, DNA Glycosylases, DNA Repair, DNA Repair Enzymes, DNA-(Apurinic or Apyrimidinic Site) Lyase, DNA-Binding Proteins, Gene-Environment Interaction, Genetic Predisposition to Disease, Humans, Neoplasms, Odds Ratio, Phenotype, Polymorphism, Single Nucleotide, Risk Assessment, Risk Factors, X-ray Repair Cross Complementing Protein 1, Pharmacology and Pharmaceutical Sciences, Toxicology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2wq71459

المؤلفون: Annie Demin, Kouji Hirota, Masataka Tsuda, Marek Adamowicz, Richard Hailstone, Jan Brazina, William Gittens, Ilona Kalasova, Zhengping Shao, Shan Zha, Hiroyuki Sasanuma, Hana Hanzlikova, Shunichi Takeda, Keith Caldecott

مصطلحات موضوعية: PARP inhibitors, PARP trapping, PARP1, XRCC1 protein complexes, base excision repair, single-strand breaks, Animals, Cell Line, DNA, DNA Breaks, Single-Stranded, DNA Damage, DNA Ligase ATP, DNA Polymerase beta, DNA Repair, DNA-Binding Proteins, Fibroblasts, Humans, Poly (ADP-Ribose) Polymerase-1, Poly(ADP-ribose) Polymerase Inhibitors, Poly(ADP-ribose) Polymerases, Protein Binding, X-ray Repair Cross Complementing Protein 1

Relation: 10779/uos.23484488.v1; https://figshare.com/articles/journal_contribution/XRCC1_prevents_toxic_PARP1_trapping_during_DNA_base_excision_repair/23484488

الاتاحة: https://figshare.com/articles/journal_contribution/XRCC1_prevents_toxic_PARP1_trapping_during_DNA_base_excision_repair/23484488

المؤلفون: Hanssen‐Bauer, Audun, Solvang‐Garten, Karin, Sundheim, Ottar, Peña‐Diaz, Javier, Andersen, Sonja, Slupphaug, Geir, Krokan, Hans E, Wilson, David M, Akbari, Mansour, Otterlei, Marit

المصدر: Environmental and Molecular Mutagenesis. 52(8)

مصطلحات موضوعية: Genetics, Animals, Blotting, Western, CHO Cells, Cell Culture Techniques, Cricetinae, Cricetulus, DNA Breaks, Single-Stranded, DNA Polymerase beta, DNA Repair, DNA-Binding Proteins, Dose-Response Relationship, Radiation, HeLa Cells, Humans, Immunoprecipitation, Lasers, Microscopy, Confocal, Models, Biological, Poly (ADP-Ribose) Polymerase-1, Poly(ADP-ribose) Polymerases, Polynucleotide 5'-Hydroxyl-Kinase, Proliferating Cell Nuclear Antigen, Recombinant Fusion Proteins, Transfection, X-ray Repair Cross Complementing Protein 1, Hela Cells, Environmental Sciences, Biological Sciences, Medical and Health Sciences, Toxicology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5hj4c2t5
https://escholarship.org/content/qt5hj4c2t5/qt5hj4c2t5.pdf

المؤلفون: McNeill, Daniel R, Lin, Ping-Chang, Miller, Marshall G, Pistell, Paul J, de Souza-Pinto, Nadja C, Fishbein, Kenneth W, Spencer, Richard G, Liu, Yie, Pettan-Brewer, Christina, Ladiges, Warren C, Wilson, David M

المصدر: Nucleic Acids Research. 39(18)

مصطلحات موضوعية: Aging, Stem Cell Research, Genetics, Digestive Diseases, Brain Disorders, Prevention, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Underpinning research, Aetiology, Good Health and Well Being, Alkylating Agents, Animals, Behavior, Animal, Body Weight, Bone Marrow Cells, Brain, Cell Survival, Chemical and Drug Induced Liver Injury, DNA-Binding Proteins, Disease Susceptibility, Female, Genomic Instability, Haploinsufficiency, Male, Mice, Mice, Inbred C57BL, Mutagens, X-ray Repair Cross Complementing Protein 1, Environmental Sciences, Biological Sciences, Information and Computing Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9pq0t8wd

المؤلفون: Berquist, Brian R, Singh, Dharmendra Kumar, Fan, Jinshui, Kim, Daemyung, Gillenwater, Elizabeth, Kulkarni, Avanti, Bohr, Vilhelm A, Ackerman, Eric J, Tomkinson, Alan E, Wilson, David M

المصدر: Nucleic Acids Research. 38(15)

مصطلحات موضوعية: Genetics, Aetiology, 2.1 Biological and endogenous factors, Generic health relevance, Amino Acid Substitution, Animals, CHO Cells, Cricetinae, Cricetulus, DNA, DNA Repair, DNA-Binding Proteins, Humans, X-ray Repair Cross Complementing Protein 1, Environmental Sciences, Biological Sciences, Information and Computing Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2sp665jj
https://escholarship.org/content/qt2sp665jj/qt2sp665jj.pdf