المؤلفون: Sjøgren, Thea, Islam, Shahinul, Filippov, Igor, Jebrzycka, Adrianna, Sulen, André, Breivik, Lars E., Hellesen, Alexander, Jørgensen, Anders P., Lima, Kari, Tserel, Liina, Kisand, Kai, Peterson, Pärt, Ranki, Annamari, Husebye, Eystein S., Oftedal, Bergithe E., Wolff, Anette S.B.

المساهمون: HUS Inflammation Center, Clinicum, Department of Dermatology, Allergology and Venereology, University of Helsinki

مصطلحات موضوعية: Components of the immune system, Health sciences, Immunology, Proteomics, Transcriptomics, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: This study was supported by grants from the Western Norway Health Authorities (T.S. E.S.H. B.E.O. A.S.B.W.). B.E.O. was supported by the Novo Nordisk Foundation (grant 103302). IF has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 955321. K.K. and P.P. were supported by the European Regional Development Fund [2014-2020.4.01.15-0012] and The Estonian Research Council Grants PRG377 and PRG1117. E.S.H was supported by the Norwegian Research Council (number 335093). The flow and mass cytometry experiments were performed at the Flow Cytometry Core Facility, Department of Clinical Science, University of Bergen. The Helios Mass Cytometer was funded by Bergen Research Foundation. We wish to thank the patients and the ROAS network consisting of endocrinologists throughout Norway, as well as the Finnish APECED and Addison associations. We are further thankful for the excellent technical help from Elisabeth Halvorsen, Hajirah Muneer, and Marie Karlsen. Finally, we would like to thank ecSeq Bioinformatics for performing the bioinformatic analysis of in vitro expanded Tregs. Storage of data was handled by resources provided by Sigma2 - the National Infrastructure for High Performance Computing and Data Storage in Norway. T.S. B.E.O. and A.S.B.W. conceived and designed the study. T.S. B.E.O. A.S.B.W. S.I. A.J. L.E.B. A.S. A.H. K.K. P.P. L.T. and I.F. acquired, processed, analyzed and interpreted the data. E.S.H. A.P.J. K.L. and A.R. recruited patients. T.S. B.E.O. and A.S.B.W. drafted the manuscript. All authors contributed to data interpretation, critically reviewed and revised the manuscript. The submitted version of the article was approved by all authors. The authors declare no competing interests. This study was supported by grants from the Western Norway Health Authorities (T.S., E.S.H., B.E.O., A.S.B.W.). B.E.O. was supported by the Novo Nordisk Foundation (grant 103302 ). IF has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 955321 . K.K. and P.P. were supported by the European Regional Development Fund [ 2014-2020.4.01.15-0012 ] and The Estonian Research Council Grants PRG377 and PRG1117 .; Sjøgren , T , Islam , S , Filippov , I , Jebrzycka , A , Sulen , A , Breivik , L E , Hellesen , A , Jørgensen , A P , Lima , K , Tserel , L , Kisand , K , Peterson , P , Ranki , A , Husebye , E S , Oftedal , B E & Wolff , A S B 2024 , ' Single cell characterization of blood and expanded regulatory T cells in autoimmune polyendocrine syndrome type 1 ' , iScience , vol. 27 , no. 4 , 109610 . https://doi.org/10.1016/j.isci.2024.109610; http://hdl.handle.net/10138/587220; 85189789528; 001227394800001

الاتاحة: http://hdl.handle.net/10138/587220

المؤلفون: Wolff, Anette S.B., Hansen, Lena, Grytaas, Marianne Aa., Oftedal, Bergithe E., Breivik, Lars, Zhou, Fan, Hufthammer, Karl Ove, Sjøgren, Thea, Olofsson, Jan Stefan, Trieu, Mai Chi, Meager, Anthony, Jørgensen, Anders P., Lima, Kari, Greve-Isdahl Mohn, Kristin, Langeland, Nina, Cox, Rebecca Jane, Husebye, Eystein S.

المساهمون: Trond Mohn stiftelse, Novo Nordisk Fonden, European Commission, Helse- og Omsorgsdepartementet, Novo Nordisk AS, Western Norway Regional Health Authority, Norges Forskningsråd, Norwegian Ministry of Education and Research

المصدر: iScience ; volume 26, issue 7, page 107084 ; ISSN 2589-0042

الاتاحة: https://doi.org/10.1016/j.isci.2023.107084
https://api.elsevier.com/content/article/PII:S2589004223011616?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2589004223011616?httpAccept=text/plain

المؤلفون: Fishman, Dmytro, Kisand, Kai, Hertel, Christina, Rothe, Mike, Remm, Anu, Pihlap, Maire, Adler, Priit, Vilo, Jaak, Peet, Aleksandr, Meloni, Antonella, Podkrajsek, Katarina Trebusak, Battelino, Tadej, Bruserud, Øyvind, Wolff, Anette S.B., Husebye, Eystein S., Kluger, Nicolas, Krohn, Kai, Ranki, Annamari, Peterson, Hedi, Hayday, Adrian, Peterson, Pärt

المصدر: Fishman , D , Kisand , K , Hertel , C , Rothe , M , Remm , A , Pihlap , M , Adler , P , Vilo , J , Peet , A , Meloni , A , Podkrajsek , K T , Battelino , T , Bruserud , Ø , Wolff , A S B , Husebye , E S , Kluger , N , Krohn , K , Ranki , A , Peterson , H , Hayday , A & Peterson , P 2017 , ' Autoantibody repertoire in APECED patients targets two distinct subgroups ....

مصطلحات موضوعية: Autoantibodies, Autoantigen, Autoimmune regulator, Immune tolerance, Thymus

وصف الملف: application/pdf

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/1e997175-6f30-4dd2-96ec-2a29e02f5662
https://doi.org/10.3389/fimmu.2017.00976
https://kclpure.kcl.ac.uk/ws/files/83579384/High_titer_autoantibodies_produced_FISHMAN_Publishedonline16August2017_GOLD_VOR_CC_BY_.pdf
http://www.scopus.com/inward/record.url?scp=85028001307&partnerID=8YFLogxK

المؤلفون: Sjøgren, Thea, Bratland, Eirik, Røyrvik, Ellen C., Grytaas, Marianne Aa., Benneche, Andreas, Knappskog, Per M., Kämpe, Olle, Oftedal, Bergithe E., Husebye, Eystein S., Wolff, Anette S.B.

المصدر: Journal of Autoimmunity ; volume 133, page 102917 ; ISSN 0896-8411

الاتاحة: http://dx.doi.org/10.1016/j.jaut.2022.102917
https://api.elsevier.com/content/article/PII:S0896841122001251?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0896841122001251?httpAccept=text/plain

المؤلفون: Meyer, Steffen, Woodward, Martin, Hertel, Christina, Vlaicu, Philip, Haque, Yasmin, Kärner, Jaanika, Macagno, Annalisa, Onuoha, Shimobi C., Fishman, Dmytro, Peterson, Hedi, Metsküla, Kaja, Uibo, Raivo, Jäntti, Kirsi, Hokynar, Kati, Wolff, Anette S.B., Krohn, Kai, Ranki, Annamari, Peterson, Pärt, Kisand, Kai, Hayday, Adrian, Meloni, Antonella, Kluger, Nicolas, Husebye, Eystein S., Podkrajsek, Katarina Trebusak, Battelino, Tadej, Bratanic, Nina, Peet, Aleksandr

المصدر: Cell ; volume 166, issue 3, page 582-595 ; ISSN 0092-8674

الاتاحة: http://dx.doi.org/10.1016/j.cell.2016.06.024
https://api.elsevier.com/content/article/PII:S0092867416307929?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0092867416307929?httpAccept=text/plain

المؤلفون: Oftedal, Bergithe E., Hellesen, Alexander, Erichsen, Martina M., Bratland, Eirik, Vardi, Ayelet, Perheentupa, Jaakko, Kemp, E. Helen, Fiskerstrand, Torunn, Viken, Marte K., Weetman, Anthony P., Fleishman, Sarel J., Banka, Siddharth, Newman, William G., Sewell, W.A.C., Sozaeva, Leila S., Zayats, Tetyana, Haugarvoll, Kristoffer, Orlova, Elizaveta M., Haavik, Jan, Johansson, Stefan, Knappskog, Per M., Løvås, Kristian, Wolff, Anette S.B., Abramson, Jakub, Husebye, Eystein S.

المساهمون: Sy Syms Foundation, Helse Vest Regionalt Helseføretak, Norges Forskningsråd, Epidermolysis Bullosa Medical Research Foundation, Israel Science Foundation, Novo Nordisk Fonden

المصدر: Immunity ; volume 42, issue 6, page 1185-1196 ; ISSN 1074-7613

الاتاحة: http://dx.doi.org/10.1016/j.immuni.2015.04.021
https://api.elsevier.com/content/article/PII:S1074761315002101?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1074761315002101?httpAccept=text/plain

المؤلفون: Kisand, Kai, Link, Maire, Wolff, Anette S.B., Meager, Anthony, Tserel, Liina, Org, Tõnis, Murumägi, Astrid, Uibo, Raivo, Willcox, Nick, Trebušak Podkrajšek, Katarina, Battelino, Tadej, Lobell, Anna, Kämpe, Olle, Lima, Kari, Meloni, Antonella, Ergun-Longmire, Berrin, Maclaren, Noel K., Perheentupa, Jaakko, Krohn, Kai J.E., Scott, Hamish S., Husebye, Eystein S., Peterson, Pärt

المصدر: Blood; October 2008, Vol. 112 Issue: 7 p2657-2666, 10p