المؤلفون: Bonsall, David R., Kokkinou, Michelle, Halff, Els F., Rutigliano, Grazia, Tang, Sac-Pham, Veronese, Mattia, Irvine, Elaine E., Withers, Dominic J., Wells, Lisa A., Natesan, Sridhar, Gerlach, Irene, Holiga, Štefan, Hoener, Marius C., Howes, Oliver D.

المساهمون: F. Hoffmann-La Roche, Wellcome Trust Digital Award, Ministero dell'Istruzione e del Merito, Medical Research Council, Wellcome Trust

المصدر: Molecular Imaging ; volume 23 ; ISSN 1535-3508 1536-0121

الاتاحة: https://doi.org/10.1177/15353508241299546
https://journals.sagepub.com/doi/pdf/10.1177/15353508241299546
https://journals.sagepub.com/doi/full-xml/10.1177/15353508241299546

المؤلفون: Prodani, Chiara, Irvine, Elaine E, Sardini, Alessandro, Gleneadie, Hannah J, Dimond, Andrew, Van de Pette, Mathew, John, Rosalind, Kokkinou, Michelle, Howes, Oliver, Withers, Dominic J, Ungless, Mark A, Merkenschlager, Matthias, Fisher, Amanda G

مصطلحات موضوعية: Animals, Female, Mice, Pregnancy, Alleles, Cyclin-Dependent Kinase Inhibitor p57, Diet, Protein-Restricted, Dopamine, Neurons, Behavior, Animal

وصف الملف: application/pdf; text/xml; application/zip

Relation: https://www.repository.cam.ac.uk/handle/1810/366985

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/366985

المؤلفون: Yu, Vanessa, Yong, Fiona, Marta, Angellica, Khadayate, Sanjay, Osakwe, Adrien, Bhattacharya, Supriyo, Varghese, Sneha S., Chabosseau, Pauline, Tabibi, Sayed M., Chen, Keran, Georgiadou, Eleni, Parveen, Nazia, Suleiman, Mara, Stamoulis, Zoe, Marselli, Lorella, De Luca, Carmela, Tesi, Marta, Ostinelli, Giada, Delgadillo-Silva, Luis, Wu, Xiwei, Hatanaka, Yuki, Montoya, Alex, Elliott, James, Patel, Bhavik, Demchenko, Nikita, Whilding, Chad, Hajkova, Petra, Shliaha, Pavel, Kramer, Holger, Ali, Yusuf, Marchetti, Piero, Sladek, Robert, Dhawan, Sangeeta, Withers, Dominic J., Rutter, Guy A., Millership, Steven J.

المساهمون: Fonds de Recherche du Québec - Santé, Ministero dell'Istruzione, dell'Università e della Ricerca, Society for Endocrinology, Wellcome Trust, National Institutes of Health, Innovation Canada John R. Evans Leaders Award, European Union’s Horizon 2020 research and innovation programme, Canadian Institutes of Health Research, City of Hope Start-up funds, Wanek Family Foundation to Cure Type 1 Diabetes, California Institute for Regenerative Medicine, Medical Research Council, Division of Diabetes, Endocrinology, and Metabolic Diseases, Institute of Nutrition, Metabolism and Diabetes, Singapore Ministry of Education Academic Research Fund Tier 2, Fondation du CHUM

المصدر: Diabetologia ; volume 67, issue 6, page 1079-1094 ; ISSN 0012-186X 1432-0428

الاتاحة: http://dx.doi.org/10.1007/s00125-024-06123-6
https://link.springer.com/content/pdf/10.1007/s00125-024-06123-6.pdf
https://link.springer.com/article/10.1007/s00125-024-06123-6/fulltext.html

المؤلفون: Petty, Alice, Garcia-Hidalgo, Anna, Halff, Els F., Natesan, Sridhar, Withers, Dominic J., Irvine, Elaine E., Kokkinou, Michelle, Wells, Lisa A., Bonsall, David R., Tang, Sac-Pham, Veronese, Mattia, Howes, Oliver D.

المصدر: Molecular Imaging and Biology ; volume 26, issue 3, page 553-553 ; ISSN 1536-1632 1860-2002

الاتاحة: https://doi.org/10.1007/s11307-024-01916-y
https://link.springer.com/content/pdf/10.1007/s11307-024-01916-y.pdf
https://link.springer.com/article/10.1007/s11307-024-01916-y/fulltext.html

المؤلفون: Mousavy Gharavy, S. Neda, Owen, Bryn M., Millership, Steven J., Chabosseau, Pauline, Pizza, Grazia, Martinez-Sanchez, Aida, Tasoez, Emirhan, Georgiadou, Eleni, Hu, Ming, Fine, Nicholas H. F., Jacobson, David A., Dickerson, Matthew T., Idevall-Hagren, Olof, 1980, Montoya, Alex, Kramer, Holger, Mehta, Zenobia, Withers, Dominic J., Ninov, Nikolay, Gadue, Paul J., Cardenas-Diaz, Fabian L., Cruciani-Guglielmacci, Celine, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Voz, Marianne, Rutter, Guy A.

المصدر: Diabetologia. 64(4):850-864

مصطلحات موضوعية: C2CD4A/B, Follicle-stimulating hormone, Genome-wide association studies, Glucose homeostasis, Type 2 diabetes

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-450003
https://doi.org/10.1007/s00125-020-05350-x
https://uu.diva-portal.org/smash/get/diva2:1583959/FULLTEXT01.pdf

المؤلفون: McHugh, Domhnall, Sun, Bin, Gutierrez-Muñoz, Carmen, Hernández-González, Fernanda, Mellone, Massimiliano, Guiho, Romain, Duran, Imanol, Pombo, Joaquim, Pietrocola, Federico, Birch, Jodie, Kallemeijn, Wouter W., Khadayate, Sanjay, Dharmalingam, Gopuraja, Vernia, Santiago, Tate, Edward W., Martínez-Barbera, Juan Pedro, Withers, Dominic J., Thomas, Gareth J., Serrano, Manuel, Gil, Jesús

وصف الملف: text

Relation: https://eprints.soton.ac.uk/493229/1/COPINMTsub18July2023.pdf; https://eprints.soton.ac.uk/493229/2/s41556-023-01287-6.pdf; McHugh, Domhnall, Sun, Bin, Gutierrez-Muñoz, Carmen, Hernández-González, Fernanda, Mellone, Massimiliano, Guiho, Romain, Duran, Imanol, Pombo, Joaquim, Pietrocola, Federico, Birch, Jodie, Kallemeijn, Wouter W., Khadayate, Sanjay, Dharmalingam, Gopuraja, Vernia, Santiago, Tate, Edward W., Martínez-Barbera, Juan Pedro, Withers, Dominic J., Thomas, Gareth J., Serrano, Manuel and Gil, Jesús (2023) COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells. Nature Cell Biology, 25 (12), 1804-1820. (doi:10.1038/s41556-023-01287-6 ).

الاتاحة: https://eprints.soton.ac.uk/493229/
https://eprints.soton.ac.uk/493229/1/COPINMTsub18July2023.pdf
https://eprints.soton.ac.uk/493229/2/s41556-023-01287-6.pdf

المؤلفون: Crombie, Elisa M, Kim, Seonyoung, Adamson, Stuart, Dong, Han, Lu, Tzu‐Chiao, Wu, Yiju, Wu, Yajun, Levy, Yotam, Stimple, Nolan, Lam, Wing Moon R, Hey, Hwee Weng D, Withers, Dominic J, Hsu, Ao‐Lin, Bay, Boon Huat, Ochala, Julien, Tsai, Shih‐Yin

المصدر: Journal of Cachexia, Sarcopenia and Muscle , 14 (1) pp. 198-213. (2023)

مصطلحات موضوعية: mitochondrial dysfunction, mRNA translation, mTORC1, protein degradation, sarcopenia

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10166974/1/Crombie%20et%20al%20J%20Cachexia%20Sarcopenia%20Muscle%202023.pdf; https://discovery.ucl.ac.uk/id/eprint/10166974/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10166974/1/Crombie%20et%20al%20J%20Cachexia%20Sarcopenia%20Muscle%202023.pdf
https://discovery.ucl.ac.uk/id/eprint/10166974/

المؤلفون: Crombie, Elisa M., Kim, Seonyoung, Adamson, Stuart, Dong, Han, Lu, Tzu Chiao, Wu, Yiju, Wu, Yajun, Levy, Yotam, Stimple, Nolan, Lam, Wing Moon R., Hey, Hwee Weng D., Withers, Dominic J., Hsu, Ao Lin, Bay, Boon Huat, Ochala, Julien, Tsai, Shih Yin

المصدر: Crombie , E M , Kim , S , Adamson , S , Dong , H , Lu , T C , Wu , Y , Wu , Y , Levy , Y , Stimple , N , Lam , W M R , Hey , H W D , Withers , D J , Hsu , A L , Bay , B H , Ochala , J & Tsai , S Y 2023 , ' Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity ' , Journal of Cachexia, Sarcopenia and Muscle , vol. 14 , ....

مصطلحات موضوعية: mitochondrial dysfunction, mRNA translation, mTORC1, protein degradation, sarcopenia

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/activation-of-eif4ebindingprotein1-rescues-mtorc1induced-sarcopenia-by-expanding-lysosomal-degradation-capacity(fd92407c-e981-438c-a123-c0c6110de446).html
https://doi.org/10.1002/jcsm.13121
https://curis.ku.dk/ws/files/355253355/Activation_of_eIF4E_binding_protein_1.pdf
http://www.scopus.com/inward/record.url?scp=85142229152&partnerID=8YFLogxK

المؤلفون: Petty, Alice, Garcia-Hidalgo, Anna, Halff, Els F, Natesan, Sridhar, Withers, Dominic J, Irvine, Elaine E, Kokkinou, Michelle, Wells, Lisa A, Bonsall, David R, Tang, Sac-Pham, Veronese, Mattia, Howes, Oliver D

المصدر: Molecular Imaging and Biology ; volume 25, issue 6, page 1054-1062 ; ISSN 1536-1632 1860-2002

الاتاحة: http://dx.doi.org/10.1007/s11307-023-01865-y
https://link.springer.com/content/pdf/10.1007/s11307-023-01865-y.pdf
https://link.springer.com/article/10.1007/s11307-023-01865-y/fulltext.html

المؤلفون: Gallage, Suchira, Ali, Adnan, Barragan avila, Jose efren, Herebian, Diran, Karimi, Mohammad M., Irvine, Elaine E., Mchugh, Domhnall, Schneider, Anne T., Vucur, Mihael, Keitel, Verena, Gil, Jesús, Withers, Dominic J., Luedde, Tom, Heikenwalder, Mathias

المصدر: Gallage , S , Ali , A , Barragan avila , J E , Herebian , D , Karimi , M M , Irvine , E E , Mchugh , D , Schneider , A T , Vucur , M , Keitel , V , Gil , J , Withers , D J , Luedde , T & Heikenwalder , M 2022 , ' Spontaneous Cholemia in C57BL/6 Mice Predisposes to Liver Cancer in NASH ' , Cellular and molecular gastroenterology and hepatology , vol. 13 , no. 3 , pp. 875-878 . https://doi.org/10.1016/j.jcmgh.2021.11.012

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/5dfe624c-c931-4cd5-8ed2-46156d99ce3b
https://doi.org/10.1016/j.jcmgh.2021.11.012

المؤلفون: Ang, Seok-Ting J., Crombie, Elisa M., Dong, Han, Tan, Kuan-Ting, Hernando, Adriel, Yu, Dejie, Adamson, Stuart, Kim, Seonyoung, Withers, Dominic J., Huang, Hua, Tsai, Shih-Yin

المساهمون: RCUK | Medical Research Council, Wellcome Trust, Ministry of Education - Singapore, MOH | National Medical Research Council, National University of Singapore

المصدر: Nature Communications ; volume 13, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-022-35547-0
https://www.nature.com/articles/s41467-022-35547-0.pdf
https://www.nature.com/articles/s41467-022-35547-0

المؤلفون: Halff, Els F., Natesan, Sridhar, Bonsall, David R., Veronese, Mattia, Garcia-Hidalgo, Anna, Kokkinou, Michelle, Tang, Sac-Pham, Riggall, Laura J., Gunn, Roger N., Irvine, Elaine E., Withers, Dominic J., Wells, Lisa A., Howes, Oliver D.

المساهمون: Vasdev, Neil, King’s College London, South London and Maudsley NHS Foundation Trust, National Institute for Health Research, Ministero dell’Istruzione, dell’Università e della Ricerca, Wellcome Trust, Medical Research Council

المصدر: Molecular Imaging ; volume 2022 ; ISSN 1535-3508 1536-0121

الاتاحة: http://dx.doi.org/10.1155/2022/4419221
http://journals.sagepub.com/doi/pdf/10.1155/2022/4419221
http://journals.sagepub.com/doi/full-xml/10.1155/2022/4419221

المؤلفون: Ninkina, Natalia, Millership, Steven J., Peters, Owen M., Connor-Robson, Natalie, Chaprov, Kirill, Kopylov, Arthur T., Montoya, Alex, Kramer, Holger, Withers, Dominic J., Buchman, Vladimir L.

وصف الملف: application/pdf

Relation: https://orca.cardiff.ac.uk/id/eprint/145257/8/PIIS0021925821011819.pdf; Ninkina, Natalia https://orca.cardiff.ac.uk/view/cardiffauthors/A0661964.html orcid:0000-0001-8570-5648 orcid:0000-0001-8570-5648, Millership, Steven J., Peters, Owen M. https://orca.cardiff.ac.uk/view/cardiffauthors/A0585092.html orcid:0000-0002-6824-0663 orcid:0000-0002-6824-0663, Connor-Robson, Natalie https://orca.cardiff.ac.uk/view/cardiffauthors/A095315G.html orcid:0000-0001-8350-6928 orcid:0000-0001-8350-6928, Chaprov, Kirill, Kopylov, Arthur T., Montoya, Alex, Kramer, Holger, Withers, Dominic J. and Buchman, Vladimir L. https://orca.cardiff.ac.uk/view/cardiffauthors/A050654U.html orcid:0000-0002-7631-8352 orcid:0000-0002-7631-8352 2021. β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins. Journal of Biological Chemistry 297 (6) , 101375. 10.1016/j.jbc.2021.101375 https://doi.org/10.1016/j.jbc.2021.101375 file https://orca.cardiff.ac.uk/id/eprint/145257/8/PIIS0021925821011819.pdf

الاتاحة: https://orca.cardiff.ac.uk/id/eprint/145257/
https://doi.org/10.1016/j.jbc.2021.101375
https://orca.cardiff.ac.uk/id/eprint/145257/8/PIIS0021925821011819.pdf

المؤلفون: Broughton, Susan J., Ikeya, Tomoatsu, Bass, Timothy M., Jacobson, Jake, Driege, Yasmine, Martinez, Pedro, Hafen, Ernst, Withers, Dominic J., Leevers, Sally J., Partridge, Linda, Kenyon, Cynthia J.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2005 Feb . 102(8), 3105-3110.

URL الوصول: https://www.jstor.org/stable/3374753

المؤلفون: Widjaja, Anissa A., Lim, Wei-Wen, Viswanathan, Sivakumar, Chothani, Sonia, Corden, Ben, Dasan, Cibi Mary, Goh, Joyce Wei Ting, Lim, Radiance, Singh, Brijesh K., Tan, Jessie, Pua, Chee Jian, Lim, Sze Yun, Adami, Eleonora, Schafer, Sebastian, George, Benjamin L., Sweeney, Mark, Xie, Chen, Tripathi, Madhulika, Sims, Natalie A., Hübner, Norbert, Petretto, Enrico, Withers, Dominic J., Ho, Lena, Gil, Jesus, Carling, David, Cook, Stuart A.

المصدر: Nature; August 2024, Vol. 632 Issue: 8023 p157-165, 9p

المؤلفون: Halff, Els F., Natesan, Sridhar, Bonsall, David R., Veronese, Mattia, Garcia-Hidalgo, Anna, Kokkinou, Michelle, Tang, Sac-Pham, Riggall, Laura J., Gunn, Roger N., Irvine, Elaine E., Withers, Dominic J., Wells, Lisa A., Howes, Oliver D., Vasdev, Neil

المصدر: Molecular Imaging; 4/10/2024, p1-12, 12p

مصطلحات موضوعية: KETAMINE, DOPAMINE, DOPAMINERGIC neurons, POSITRON emission tomography, INTRACLASS correlation, METHYL aspartate receptors, JUGULAR vein, RADIOACTIVE tracers

المؤلفون: Howes, Oliver, Kokkinou, Michelle, Natesan, Sridhar, Irving, Elaine, Bonsall, David R., Wells, Lisa A, Smith, Mark, Glegola, Justyna, Paul, Eleanor, Tossell, Kyoko, Veronese, Mattia, Khadayate, Sanjay, Dedic, Nina, Hopkins, Seth, Ungless, Mark A, Withers, Dominic J.

المصدر: Howes , O , Kokkinou , M , Natesan , S , Irving , E , Bonsall , D R , Wells , L A , Smith , M , Glegola , J , Paul , E , Tossell , K , Veronese , M , Khadayate , S , Dedic , N , Hopkins , S , Ungless , M A & Withers , D J 2020 , ' Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it : a translational imaging study with ketamine ' , Molecular Psychiatry , vol. 0 , no. 0 , ....

وصف الملف: application/pdf

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/221763ec-1891-4cc0-9571-c55fa73f699d
https://doi.org/10.1038/s41380-020-0740-6
https://kclpure.kcl.ac.uk/ws/files/127047320/Reproducing_the_dopamine_pathophysiology_HOWES_Accepted6Apr2020_GREEN_AAM.pdf
https://kclpure.kcl.ac.uk/ws/files/148488834/Reproducing_the_dopamine_pathophysiology_HOWES_Accepted6Apr2020_GOLD_VoR_CC_BY_.pdf
http://www.scopus.com/inward/record.url?scp=85085070146&partnerID=8YFLogxK

المؤلفون: Smith, Mark A., Choudhury, Agharul I., Glegola, Justyna A., Viskaitis, Paulius, Irvine, Elaine E., De Campos Silva, Pedro C.C., Khadayate, Sanjay, Zeilhofer, Hanns U., Withers, Dominic J.

المصدر: The Journal of Clinical Investigation, 130 (1)

وصف الملف: application/application/pdf

Relation: info:eu-repo/semantics/altIdentifier/wos/000505205000021; http://hdl.handle.net/20.500.11850/389541

الاتاحة: https://hdl.handle.net/20.500.11850/389541
https://doi.org/10.3929/ethz-b-000389541

المؤلفون: Guerrero, Ana, Guiho, Romain, Herranz, Nicolás, Uren, Anthony, Withers, Dominic J., Martínez‐Barbera, Juan Pedro, Tietze, Lutz F., Gil, Jesús

المساهمون: Brain Tumour Charity, CHILDREN with CANCER UK, Cancer Research UK

المصدر: Aging Cell ; volume 19, issue 4 ; ISSN 1474-9718 1474-9726

الاتاحة: http://dx.doi.org/10.1111/acel.13133
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Facel.13133
https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.13133
https://onlinelibrary.wiley.com/doi/full-xml/10.1111/acel.13133

المؤلفون: Duran, Imanol, Pombo, Joaquim, Sun, Bin, Gallage, Suchira, Kudo, Hiromi, McHugh, Domhnall, Bousset, Laura, Barragan Avila, Jose Efren, Forlano, Roberta, Manousou, Pinelopi, Heikenwalder, Mathias, Withers, Dominic J., Vernia, Santiago, Goldin, Robert D., Gil, Jesús

المصدر: Nature Communications; 2/3/2024, Vol. 15 Issue 1, p1-20, 20p

مصطلحات موضوعية: MACHINE learning, AGING, CELLULAR aging, FATTY liver, DRUG efficacy, LIVER cancer