المؤلفون: Xie, S. C., Metcalfe, R. D., Mizutani, H., Puhalovich, T., Hanssen, E., Morton, C. J., Du, Y., Dogovski, C., Huang, S. C., Ciavarri, J., Hales, P., Griffin, R. J., Cohen, L. H., Chuang, B. C., Wittlin, S., Deni, I., Yeo, T., Ward, K. E., Barry, D. C., Liu, B., Gillett, D. L., Crespo-Fernandez, B. F., Ottilie, S., Mittal, N., Churchyard, A., Ferguson, D., Aguiar, A. C. C., Guido, R. V. C., Baum, J., Hanson, K. K., Winzeler, E. A., Gamo, F. J., Fidock, D. A., Baud, D., Parker, M. W., Brand, S., Dick, L. R., Griffin, M. D. W., Gould, A. E., Tilley, L.

وصف الملف: application/pdf

Relation: https://edoc.unibas.ch/89612/1/20220819105619_62ff50334e005.pdf; Xie, S. C. and Metcalfe, R. D. and Mizutani, H. and Puhalovich, T. and Hanssen, E. and Morton, C. J. and Du, Y. and Dogovski, C. and Huang, S. C. and Ciavarri, J. and Hales, P. and Griffin, R. J. and Cohen, L. H. and Chuang, B. C. and Wittlin, S. and Deni, I. and Yeo, T. and Ward, K. E. and Barry, D. C. and Liu, B. and Gillett, D. L. and Crespo-Fernandez, B. F. and Ottilie, S. and Mittal, N. and Churchyard, A. and Ferguson, D. and Aguiar, A. C. C. and Guido, R. V. C. and Baum, J. and Hanson, K. K. and Winzeler, E. A. and Gamo, F. J. and Fidock, D. A. and Baud, D. and Parker, M. W. and Brand, S. and Dick, L. R. and Griffin, M. D. W. and Gould, A. E. and Tilley, L. (2021) Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proc Natl Acad Sci U S A, 118 (39). e2107213118.; info:pmid/34548400; urn:ISSN:1091-6490 (Electronic)0027-8424 (Linking)

الاتاحة: https://edoc.unibas.ch/89612/
https://edoc.unibas.ch/89612/1/20220819105619_62ff50334e005.pdf
https://doi.org/10.1073/pnas.2107213118

المؤلفون: Imlay, L. S., Lawong, A. K., Gahalawat, S., Kumar, A., Xing, C., Mittal, N., Wittlin, S., Churchyard, A., Niederstrasser, H., Crespo-Fernandez, B., Posner, B. A., Gamo, F. J., Baum, J., Winzeler, E. A., Laleu, B., Ready, J. M., Phillips, M. A.

Relation: Imlay, L. S. and Lawong, A. K. and Gahalawat, S. and Kumar, A. and Xing, C. and Mittal, N. and Wittlin, S. and Churchyard, A. and Niederstrasser, H. and Crespo-Fernandez, B. and Posner, B. A. and Gamo, F. J. and Baum, J. and Winzeler, E. A. and Laleu, B. and Ready, J. M. and Phillips, M. A. (2023) Fast-killing tyrosine amide ((S)-SW228703) with blood- and liver-stage antimalarial activity associated with the cyclic amine resistance locus (PfCARL). ACS Infect Dis, 9 (3). pp. 527-539.; info:pmid/36763526; urn:ISSN:2373-8227 (Electronic)2373-8227 (Linking)

الاتاحة: https://edoc.unibas.ch/94535/
https://doi.org/10.1021/acsinfecdis.2c00527

المؤلفون: Nguyen, W., Dans, M. G., Currie, I., Awalt, J. K., Bailey, B. L., Lumb, C., Ngo, A., Favuzza, P., Palandri, J., Ramesh, S., Penington, J., Jarman, K. E., Mukherjee, P., Chakraborty, A., Maier, A. G., van Dooren, G. G., Papenfuss, T., Wittlin, S., Churchyard, A., Baum, J., Winzeler, E. A., Baud, D., Brand, S., Jackson, P. F., Cowman, A. F., Sleebs, B. E.

Relation: Nguyen, W. and Dans, M. G. and Currie, I. and Awalt, J. K. and Bailey, B. L. and Lumb, C. and Ngo, A. and Favuzza, P. and Palandri, J. and Ramesh, S. and Penington, J. and Jarman, K. E. and Mukherjee, P. and Chakraborty, A. and Maier, A. G. and van Dooren, G. G. and Papenfuss, T. and Wittlin, S. and Churchyard, A. and Baum, J. and Winzeler, E. A. and Baud, D. and Brand, S. and Jackson, P. F. and Cowman, A. F. and Sleebs, B. E. (2023) 7-N-substituted-3-oxadiazole quinolones with potent antimalarial activity target the cytochrome bc1 complex. ACS Infect Dis, 9 (3). pp. 668-691.; info:pmid/36853190; urn:ISSN:2373-8227 (Electronic)2373-8227 (Linking)

الاتاحة: https://edoc.unibas.ch/94553/
https://doi.org/10.1021/acsinfecdis.2c00607

المؤلفون: Delves, M, Miguel-Blanco, C, Matthews, H, Molina, I, Ruecker, A, Yahiya, S, Straschil, U, Abraham, M, Leon-Diaz, ML, Fischer, O, Zubiaurre, A, Brandt, J, Cortes, A, Barnard, A, Fuchter, M, Calderon, F, Winzeler, E, Sinden, R, Herreros, E, Gamo, FJ, Baum, J

المساهمون: Bill & Melinda Gates Foundation, Wellcome Trust, Engineering & Physical Science Research Council (EPSRC)

مصطلحات موضوعية: MD Multidisciplinary

Relation: Nature Communications; http://hdl.handle.net/10044/1/62850; https://dx.doi.org/10.1038/s41467-018-05777-2; OPP1043501; 100993/Z/13/Z; EP/L014580/1

الاتاحة: http://hdl.handle.net/10044/1/62850
https://doi.org/10.1038/s41467-018-05777-2

المؤلفون: Rabinovich, R, Drakeley, C, Djimde, A, Hall, B, Hay, S, Hemingway, J, Kaslow, D, Noor, A, Okumu, F, Steketee, R, Tanner, M, Wells, T, Whittaker, M, Winzeler, E, Wirth, D, Whitfield, K, Alonso, P

Relation: https://ora.ox.ac.uk/objects/uuid:e18e4392-6131-4423-8ea3-7e16b511d9d4; https://doi.org/10.1371/journal.pmed.1002456

الاتاحة: https://doi.org/10.1371/journal.pmed.1002456
https://ora.ox.ac.uk/objects/uuid:e18e4392-6131-4423-8ea3-7e16b511d9d4

المؤلفون: Williamson, A, Ylioja, P, Robertson, M, Antonova-Koch, Y, Avery, V, Baell, J, Batchu, H, Batra, S, Burrows, J, Bhattacharyya, S, Calderon, F, Charman, S, Clark, J, Crespo, B, Dean, M, Debbert, S, Delves, M, Dennis, A, Deroose, F, Duffy, S, Fletcher, S, Giaever, G, Hallyburton, I, Gamo, F, Gebbia, M, Guy, R, Hungerford, Z, Kirk, K, Lafuente-Monasterio, M, Lee, A, Meister, S, Nislow, C, Overington, J, Papadatos, G, Patiny, L, Pham, J, Ralph, S, Ruecker, A, Ryan, E, Southan, C, Srivastava, K, Swain, C, Tarnowski, M, Thomson, P, Turner, P, Wallace, I, Wells, T, White, K, White, L, Willis, P, Winzeler, E, Wittlin, S, Todd, M

Relation: https://ora.ox.ac.uk/objects/uuid:32cd3d14-3f69-473b-ae1d-94aac7d96e04; https://doi.org/10.1021/acscentsci.6b00086

الاتاحة: https://doi.org/10.1021/acscentsci.6b00086
https://ora.ox.ac.uk/objects/uuid:32cd3d14-3f69-473b-ae1d-94aac7d96e04

المؤلفون: Ottilie, S., Luth, M. R., Hellemann, E., Goldgof, G. M., Vigil, E., Kumar, P., Cheung, A. L., Song, M., Godinez-Macias, K. P., Carolino, K., Yang, J., Lopez, G., Abraham, M., Tarsio, M., Leblanc, Eric, Whitesell, L., Schenken, J., Gunawan, F., Patel, R., Smith, J., Love, M. S., Williams, R. M., Mcnamara, C. W., Gerwick, W. H., Ideker, T., Suzuki, Y., Wirth, D. F., Lukens, A. K., Kane, P. M., Cowen, L. E., Durrant, J. D., Winzeler, E. A.

المساهمون: Université de Lille, Inserm, CHU Lille, Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192

Relation: Commun Biol; http://hdl.handle.net/20.500.12210/92616

الاتاحة: https://hdl.handle.net/20.500.12210/92616

المؤلفون: Xie, S. C., Metcalfe, R. D., Dunn, E., Morton, C. J., Huang, S. C., Puhalovich, T., Du, Y., Wittlin, S., Nie, S., Luth, M. R., Ma, L., Kim, M. S., Pasaje, C. F. A., Kumpornsin, K., Giannangelo, C., Houghton, F. J., Churchyard, A., Famodimu, M. T., Barry, D. C., Gillett, D. L., Dey, S., Kosasih, C. C., Newman, W., Niles, J. C., Lee, M. C. S., Baum, J., Ottilie, S., Winzeler, E. A., Creek, D. J., Williamson, N., Parker, M. W., Brand, S., Langston, S. P., Dick, L. R., Griffin, M. D. W., Gould, A. E., Tilley, L.

Relation: Xie, S. C. and Metcalfe, R. D. and Dunn, E. and Morton, C. J. and Huang, S. C. and Puhalovich, T. and Du, Y. and Wittlin, S. and Nie, S. and Luth, M. R. and Ma, L. and Kim, M. S. and Pasaje, C. F. A. and Kumpornsin, K. and Giannangelo, C. and Houghton, F. J. and Churchyard, A. and Famodimu, M. T. and Barry, D. C. and Gillett, D. L. and Dey, S. and Kosasih, C. C. and Newman, W. and Niles, J. C. and Lee, M. C. S. and Baum, J. and Ottilie, S. and Winzeler, E. A. and Creek, D. J. and Williamson, N. and Parker, M. W. and Brand, S. and Langston, S. P. and Dick, L. R. and Griffin, M. D. W. and Gould, A. E. and Tilley, L. (2022) Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy. Science, 376 (6597). pp. 1074-1079.; info:pmid/35653481; urn:ISSN:0036-8075

الاتاحة: https://edoc.unibas.ch/91015/
https://doi.org/10.1126/science.abn0611

المؤلفون: Laleu, B., Rubiano, K., Yeo, T., Hallyburton, I., Anderson, M., Crespo-Fernandez, B., Gamo, F. J., Antonova-Koch, Y., Orjuela-Sanchez, P., Wittlin, S., Jana, G. P., Maity, B. C., Chenu, E., Duffy, J., Sjo, P., Waterson, D., Winzeler, E., Guantai, E., Fidock, D. A., Hansson, T.

Relation: Laleu, B. and Rubiano, K. and Yeo, T. and Hallyburton, I. and Anderson, M. and Crespo-Fernandez, B. and Gamo, F. J. and Antonova-Koch, Y. and Orjuela-Sanchez, P. and Wittlin, S. and Jana, G. P. and Maity, B. C. and Chenu, E. and Duffy, J. and Sjo, P. and Waterson, D. and Winzeler, E. and Guantai, E. and Fidock, D. A. and Hansson, T. (2022) Exploring a tetrahydroquinoline antimalarial hit from the medicines for malaria pathogen box and the identification of its mode of resistance as PfeEF2. ChemMedChem, 17 (22). e202200393.; info:pmid/36129427; urn:ISSN:1860-7187 (Electronic)1860-7179 (Linking)

الاتاحة: https://edoc.unibas.ch/90603/
https://doi.org/10.1002/cmdc.202200393

المؤلفون: Delves, M, Plouffe, D, Scheurer, C, Meister, S, Wittlin, S, Winzeler, E, Sinden, R, Leroy, D

Relation: https://ora.ox.ac.uk/objects/uuid:71a03dd8-6257-4b49-84b7-22733ac9e83b; https://doi.org/10.1371/journal.pmed.1001169

الاتاحة: https://doi.org/10.1371/journal.pmed.1001169
https://ora.ox.ac.uk/objects/uuid:71a03dd8-6257-4b49-84b7-22733ac9e83b

المؤلفون: Kuhen, K, Chatterjee, A, Rottmann, M, Gagaring, K, Borboa, R, Buenviaje, J, Chen, Z, Francek, C, Wu, T, Nagle, A, Barnes, S, Plouffe, D, Lee, M, Fidock, D, Graumans, W, van de Vegte-Bolmer, M, van Gemert, G, Wirjanata, G, Sebayang, B, Marfurt, J, Russell, B, Suwanarusk, R, Price, R, Nosten, F, Tungtaeng, A, Gettayacamin, M, Sattabongkot, J, Taylor, J, Walker, J, Tully, D, Patra, K, Flannery, E, Vinetz, J, Renia, L, Sauerwein, R, Winzeler, E, Glynne, R, Diagana, T

Relation: https://ora.ox.ac.uk/objects/uuid:1be6ab4f-8757-4a44-9bc4-55f306597df4; https://doi.org/10.1128/aac.02727-13

الاتاحة: https://doi.org/10.1128/aac.02727-13
https://ora.ox.ac.uk/objects/uuid:1be6ab4f-8757-4a44-9bc4-55f306597df4

المؤلفون: Palmer, M. J., Deng, X., Watts, S., Krilov, G., Gerasyuto, A., Kokkonda, S., El Mazouni, F., White, J., White, K. L., Striepen, J., Bath, J., Schindler, K. A., Yeo, T., Shackleford, D. M., Mok, S., Deni, I., Lawong, A., Huang, A., Chen, G., Wang, W., Jayaseelan, J., Katneni, K., Patil, R., Saunders, J., Shahi, S. P., Chittimalla, R., Angulo-Barturen, I., Jimenez-Diaz, M. B., Wittlin, S., Tumwebaze, P. K., Rosenthal, P. J., Cooper, R. A., Aguiar, A. C. C., Guido, R. V. C., Pereira, D. B., Mittal, N., Winzeler, E. A., Tomchick, D. R., Laleu, B., Burrows, J. N., Rathod, P. K., Fidock, D. A., Charman, S. A., Phillips, M. A.

Relation: Palmer, M. J. and Deng, X. and Watts, S. and Krilov, G. and Gerasyuto, A. and Kokkonda, S. and El Mazouni, F. and White, J. and White, K. L. and Striepen, J. and Bath, J. and Schindler, K. A. and Yeo, T. and Shackleford, D. M. and Mok, S. and Deni, I. and Lawong, A. and Huang, A. and Chen, G. and Wang, W. and Jayaseelan, J. and Katneni, K. and Patil, R. and Saunders, J. and Shahi, S. P. and Chittimalla, R. and Angulo-Barturen, I. and Jimenez-Diaz, M. B. and Wittlin, S. and Tumwebaze, P. K. and Rosenthal, P. J. and Cooper, R. A. and Aguiar, A. C. C. and Guido, R. V. C. and Pereira, D. B. and Mittal, N. and Winzeler, E. A. and Tomchick, D. R. and Laleu, B. and Burrows, J. N. and Rathod, P. K. and Fidock, D. A. and Charman, S. A. and Phillips, M. A. (2021) Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series. Journal of medicinal chemistry, 64 (9). pp. 6085-6136.; info:pmid/33876936; urn:ISSN:0022-2623

الاتاحة: https://edoc.unibas.ch/89313/
https://doi.org/10.1021/acs.jmedchem.1c00173

المؤلفون: Le Manach, C., Dam, J., Woodland, J. G., Kaur, G., Khonde, L. P., Brunschwig, C., Njoroge, M., Wicht, K. J., Horatscheck, A., Paquet, T., Boyle, G. A., Gibhard, L., Taylor, D., Lawrence, N., Yeo, T., Mok, S., Eastman, R. T., Dorjsuren, D., Talley, D. C., Guo, H., Simeonov, A., Reader, J., van der Watt, M., Erlank, E., Venter, N., Zawada, J. W., Aswat, A., Nardini, L., Coetzer, T. L., Lauterbach, S. B., Bezuidenhout, B. C., Theron, A., Mancama, D., Koekemoer, L. L., Birkholtz, L. M., Wittlin, S., Delves, M., Ottilie, S., Winzeler, E. A., von Geldern, T. W., Smith, D., Fidock, D. A., Street, L. J., Basarab, G. S., Duffy, J., Chibale, K.

Relation: Le Manach, C. and Dam, J. and Woodland, J. G. and Kaur, G. and Khonde, L. P. and Brunschwig, C. and Njoroge, M. and Wicht, K. J. and Horatscheck, A. and Paquet, T. and Boyle, G. A. and Gibhard, L. and Taylor, D. and Lawrence, N. and Yeo, T. and Mok, S. and Eastman, R. T. and Dorjsuren, D. and Talley, D. C. and Guo, H. and Simeonov, A. and Reader, J. and van der Watt, M. and Erlank, E. and Venter, N. and Zawada, J. W. and Aswat, A. and Nardini, L. and Coetzer, T. L. and Lauterbach, S. B. and Bezuidenhout, B. C. and Theron, A. and Mancama, D. and Koekemoer, L. L. and Birkholtz, L. M. and Wittlin, S. and Delves, M. and Ottilie, S. and Winzeler, E. A. and von Geldern, T. W. and Smith, D. and Fidock, D. A. and Street, L. J. and Basarab, G. S. and Duffy, J. and Chibale, K. (2021) Identification and profiling of a novel diazaspiro[3.4]octane chemical series active against multiple stages of the human malaria parasite Plasmodium falciparum and optimization efforts. Journal of medicinal chemistry, 64 (4). pp. 2291-2309.; info:pmid/33573376; urn:ISSN:0022-2623

الاتاحة: https://edoc.unibas.ch/89177/
https://doi.org/10.1021/acs.jmedchem.1c00034

المؤلفون: Lawong, A., Gahalawat, S., Okombo, J., Striepen, J., Yeo, T., Mok, S., Deni, I., Bridgford, J. L., Niederstrasser, H., Zhou, A., Posner, B., Wittlin, S., Gamo, F. J., Crespo, B., Churchyard, A., Baum, J., Mittal, N., Winzeler, E., Laleu, B., Palmer, M. J., Charman, S. A., Fidock, D. A., Ready, J. M., Phillips, M. A.

Relation: Lawong, A. and Gahalawat, S. and Okombo, J. and Striepen, J. and Yeo, T. and Mok, S. and Deni, I. and Bridgford, J. L. and Niederstrasser, H. and Zhou, A. and Posner, B. and Wittlin, S. and Gamo, F. J. and Crespo, B. and Churchyard, A. and Baum, J. and Mittal, N. and Winzeler, E. and Laleu, B. and Palmer, M. J. and Charman, S. A. and Fidock, D. A. and Ready, J. M. and Phillips, M. A. (2021) Novel antimalarial tetrazoles and amides active against the hemoglobin degradation pathway in Plasmodium falciparum. Journal of medicinal chemistry, 64 (5). pp. 2739-2761.; info:pmid/33620219; urn:ISSN:0022-2623

الاتاحة: https://edoc.unibas.ch/89178/
https://doi.org/10.1021/acs.jmedchem.0c02022

المؤلفون: Daily, J. P., Scanfeld, D., Pochet, N., Le Roch, K., Plouffe, D., Kamal, M., Sarr, O., Mboup, S., Ndir, O., Wypij, D., Levasseur, K., Thomas, E., Tamayo, P., Dong, C., Zhou, Y., Lander, E. S., Ndiaye, D., Wirth, D., Winzeler, E. A., Mesirov, J. P., Regev, A.

المصدر: Nature ; volume 450, issue 7172, page 1091-1095 ; ISSN 0028-0836 1476-4687

الاتاحة: http://dx.doi.org/10.1038/nature06311
http://www.nature.com/articles/nature06311.pdf
http://www.nature.com/articles/nature06311

المؤلفون: Karlyshev, A. V., Oyston, P. C. F., Williams, K., Clark, G. C., Titball, R. W., Winzeler, E. A., Wren, B. W.

المساهمون: Barbieri, J. T.

المصدر: Infection and Immunity ; volume 69, issue 12, page 7810-7819 ; ISSN 0019-9567 1098-5522

الاتاحة: http://dx.doi.org/10.1128/iai.69.12.7810-7819.2001
https://journals.asm.org/doi/pdf/10.1128/IAI.69.12.7810-7819.2001

المؤلفون: Winzeler, E. A, Schena, M, Davis, R. W

المصدر: Methods in enzymology. 306

مصطلحات موضوعية: Life Sciences (General)

URL الوصول: https://ntrs.nasa.gov/citations/20040141876

المؤلفون: Bright, A, Alenazi, T, Shokoples, S, Tarning, J, Paganotti, G, White, N, Houston, S, Winzeler, E, Yanow, S

Relation: https://ora.ox.ac.uk/objects/uuid:4cf451a1-903e-44c5-bdf9-c66709fcac9b; https://doi.org/10.3201/eid1905.121852

الاتاحة: https://doi.org/10.3201/eid1905.121852
https://ora.ox.ac.uk/objects/uuid:4cf451a1-903e-44c5-bdf9-c66709fcac9b

المؤلفون: Carret, C, Horrocks, P, Konfortov, B, Winzeler, E, Qureshi, M, Newbold, C, Ivens, A

Relation: https://ora.ox.ac.uk/objects/uuid:19c3ed1d-ccfc-42d6-a2e8-135697fe6b23; https://doi.org/10.1016/j.molbiopara.2005.08.010

الاتاحة: https://doi.org/10.1016/j.molbiopara.2005.08.010
https://ora.ox.ac.uk/objects/uuid:19c3ed1d-ccfc-42d6-a2e8-135697fe6b23

المؤلفون: Karlyshev, A.V., Dorrell, N., Winzeler, E., Wren, B.W.

المساهمون: Wren, Brendan, Dorrell, Nick

مصطلحات موضوعية: Allied health professions and studies, Biological sciences, Epidemiology and public health, Infection and immunology

Relation: Karlyshev, A.V., Dorrell, N., Winzeler, E. and Wren, B.W. (2002) Further strategies for signature-tagged mutagenesis and the application of oligonucleotide microarrays for the quantification of DNA-tagged strains. In: Wren, Brendan and Dorrell, Nick, (eds.) Functional Microbial Genomics. London : Academic Press. pp. 167-184. (Methods in Microbiology, (33)) ISSN (print) 0580-9517 ISBN 9780125215336

الاتاحة: https://eprints.kingston.ac.uk/id/eprint/21957/
https://doi.org/10.1016/S0580-9517(02)33011-3