المؤلفون: Breno A. Soares, Thirumal Yempala, Darío Martínez-Afani, Williams Acevedo-Fuentes, José Brea, María Isabel Loza, Marta Cimadevila, Bruce K. Cassels

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Pharmacology, Cancer, Inorganic Chemistry, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tryptamines often results, toggle switch associated, orthosteric binding site, fourfold selectivity among, fold higher affinities, dibenzofuryl portion dives, calcium mobilization assay, amine nitrogen atom, low micromolar range, q , 2c , 2b , 2 , somewhat higher efficacy, position decreased affinity, may increase affinity, >‑ dibenzofuranylmethyl substitution, nearly full agonists, 48

Relation: https://figshare.com/articles/journal_contribution/Effect_of_Bulky_i_N_i_Dibenzofuranylmethyl_Substitution_on_the_5_HT_sub_2_sub_Receptor_Affinity_and_Efficacy_of_a_Psychedelic_Phenethylamine/25033568

الاتاحة: https://doi.org/10.1021/acschemneuro.3c00639.s001
https://figshare.com/articles/journal_contribution/Effect_of_Bulky_i_N_i_Dibenzofuranylmethyl_Substitution_on_the_5_HT_sub_2_sub_Receptor_Affinity_and_Efficacy_of_a_Psychedelic_Phenethylamine/25033568

المؤلفون: César Mattar, Gonzalo Fuentes-Barros, Leonel Liberona, Williams Acevedo-Fuentes, Bruce K. Cassels, Sebastián Castro-Saavedra, Cristian Tirapegui

المصدر: Fitoterapia. 127:179-185

مصطلحات موضوعية: Aporphines, Phytochemistry, Norreticuline, Plant Roots, 01 natural sciences, chemistry.chemical_compound, Alkaloids, Tandem Mass Spectrometry, Drug Discovery, Boldine, Chromatography, High Pressure Liquid, Pharmacology, Traditional medicine, biology, Plant Extracts, 010405 organic chemistry, Alkaloid, General Medicine, Isoquinolines, biology.organism_classification, Wood, Glaucine, 0104 chemical sciences, Plant Leaves, 010404 medicinal & biomolecular chemistry, chemistry, Peumus, visual_art, Plant Bark, visual_art.visual_art_medium, Bark, Boldo, Coclaurine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c525d1e0febeed780a74f39ccb255b38
https://doi.org/10.1016/j.fitote.2018.02.020

المؤلفون: Carolina Mascayano, Macarena Rojas-Poblete, Pablo Dahech, Williams Acevedo-Fuentes, Claudia Torrent, Pablo Barrias, Cristian Tirapegui

المصدر: Bioorganic & Medicinal Chemistry Letters. 27:1649-1653

مصطلحات موضوعية: 0301 basic medicine, Phenylhydrazines, Clinical Biochemistry, Pharmaceutical Science, Chemistry Techniques, Synthetic, Imides, Benzoates, 01 natural sciences, Biochemistry, Antioxidants, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Lipoxygenase, Non-competitive inhibition, Drug Discovery, Arachidonate 15-Lipoxygenase, Humans, Organic chemistry, Lipoxygenase Inhibitors, Imide, Molecular Biology, Benzoic acid, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Active site, Combinatorial chemistry, 0104 chemical sciences, Molecular Docking Simulation, Hydrazines, 030104 developmental biology, Docking (molecular), Lipophilicity, biology.protein, Molecular Medicine, Soybeans, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f8b2561d0ec0caddc1e9bb67fd9039
https://doi.org/10.1016/j.bmcl.2017.03.017

المؤلفون: Andrés Barriga, Williams Acevedo-Fuentes, Marcelo Vilches-Herrera, Gonzalo Fuentes-Barros, Bruce K. Cassels, Cristian Tirapegui, Sebastián Castro-Saavedra

المصدر: Journal of the Chilean Chemical Society. 61:3076-3080

مصطلحات موضوعية: Reticuline, Cryptocarya, 010405 organic chemistry, Stereochemistry, General Chemistry, Aporphines, Lauraceae, Biology, biology.organism_classification, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, Phytochemical, Botany, Boldine, Cryptocarya alba, Coclaurine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e198b3a63175a0f5bac79313558679fd
https://doi.org/10.4067/s0717-97072016000300014

المؤلفون: Giordano, Ady, Fuentes-Barros, Gonzalo, Castro-Saavedra, Sebastián, González-Cooper, Antonia, Suárez-Rozas, Cristian, Salas-Norambuena, Julio, Williams Acevedo-Fuentes, Leyton, Felipe, Tirapegui, Cristian, Echeverría, Javier, Claros, Sandra, Cassels, Bruce K.

مصطلحات موضوعية: FOS: Clinical medicine, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386e20576fb8eeedf545e42f2fcfb591

المؤلفون: Bruce K. Cassels, Williams Acevedo-Fuentes

المصدر: Magnetic Resonance in Chemistry. 54:597-600

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Stereochemistry, General Materials Science, General Chemistry, Carbon-13 NMR, Conformational isomerism, Two-dimensional nuclear magnetic resonance spectroscopy, Benzazepine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bd99523036481ebf4f81efccd194bcf4
https://doi.org/10.1002/mrc.4406

المؤلفون: Macarena Rojas-Poblete, Cristian Tirapegui, Carolina Mascayano, Williams Acevedo-Fuentes, Claudia Torrent, Pablo Barrias, Pablo Dahech

المصدر: Bioorganicmedicinal chemistry letters. 27(17)

مصطلحات موضوعية: biology, Drug discovery, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Clinical biochemistry, Combinatorial chemistry, Molecular medicine, Lipoxygenase, Drug Discovery, biology.protein, Molecular Medicine, Pharmaceutical sciences, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5196a704d31531b5a4436999c5fc15a1
https://pubmed.ncbi.nlm.nih.gov/28318946

المؤلفون: Felipe Leyton, Cristian Tirapegui, Julio Salas-Norambuena, Gonzalo Fuentes-Barros, Sebastián Castro-Saavedra, Cristian Suárez-Rozas, Sandra Claros, Bruce K. Cassels, Ady Giordano, Antonia González-Cooper, Javier Echeverría, Williams Acevedo-Fuentes

المصدر: Natural Product Communications. 14:1934578X1985625

مصطلحات موضوعية: Pharmacology, biology, 010405 organic chemistry, Sclerophyll, food and beverages, Biomass, Plant Science, General Medicine, biology.organism_classification, 01 natural sciences, Uhplc ms ms, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, Polyphenol, visual_art, Drug Discovery, Botany, visual_art.visual_art_medium, Bark, Cryptocarya alba, Tree species

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c18a848fea34a2478f34d23b188a0afc
https://doi.org/10.1177/1934578x19856258