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1Academic Journal
المؤلفون: Legge, Danny N, Collard, Tracey J, Stanko, Ewelina, Hoskin, Ashley J, Holt, Amy K, Bull, Caroline J, Kollareddy, Madhu, Bellamy, Jake, Groves, Sarah, Ma, Eric H, Hazelwood, Emma, Qualtrough, David, Amulic, Borko, Malik, Karim, Williams, Ann C, Jones, Nicholas, Vincent, Emma E
مصطلحات موضوعية: Adenocarcinoma, Adenoma, Asparagine, Asparagine synthetase, Colorectal cancer, Oncometabolism, Humans, Colorectal Neoplasms, Glycolysis, Disease Progression, Cell Proliferation, Citric Acid Cycle, Cell Line, Tumor, Glutamine, Signal Transduction, Mechanistic Target of Rapamycin Complex 1
وصف الملف: Print-Electronic; application/pdf
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2
المؤلفون: Haycock, Philip C, Borges, Maria Carolina, Burrows, Kimberley, Lemaitre, Rozenn N, Burgess, Stephen, Khankari, Nikhil K, Tsilidis, Konstantinos K, Gaunt, Tom R, Hemani, Gibran, Zheng, Jie, Truong, Therese, Birmann, Brenda M, OMara, Tracy, Spurdle, Amanda B, Iles, Mark M, Law, Matthew H, Slager, Susan L, Saberi Hosnijeh, Fatemeh, Mariosa, Daniela, Cotterchio, Michelle, Cerhan, James R, Peters, Ulrike, Enroth, Stefan, 1976, Gharahkhani, Puya, Le Marchand, Loic, Williams, Ann C, Block, Robert C, Amos, Christopher I, Hung, Rayjean J, Zheng, Wei, Gunter, Marc J, Smith, George Davey, Relton, Caroline, Martin, Richard M
المصدر: EBioMedicine. 91
مصطلحات موضوعية: Cancer risk, Delta-5 desaturase, Delta-6 desaturase, Mendelian randomization, Omega 3, Omega 6, Polyunsaturated fatty acids
وصف الملف: electronic
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3
المؤلفون: Nounu, Aayah, Greenhough, Alexander, Heesom, Kate J., Richmond, Rebecca C., Zheng, Jie, Weinstein, Stephanie J., Albanes, Demetrius, Baron, John A., Hopper, John L., Figueiredo, Jane C., Newcomb, Polly A., Lindor, Noralane M., Casey, Graham, Platz, Elizabeth A., Le Marchand, Loc, Ulrich, Cornelia M., Li, Christopher I., van Duijnhoven, Franzel J.B., Gsur, Andrea, Campbell, Peter T., Moreno, Víctor, Vodicka, Pavel, Vodickova, Ludmila, Brenner, Hermann, Chang-Claude, Jenny, Hoffmeister, Michael, Sakoda, Lori C., Slattery, Martha L., Schoen, Robert E., Gunter, Marc J., Castellví-Bel, Sergi, Kim, Hyeong Rok, Kweon, Sun-Seog, Chan, Andrew T., Li, Li, Zheng, Wei, Bishop, D. Timothy, Buchanan, Daniel D., Giles, Graham G., Gruber, Stephen B., Rennert, Gad, Stadler, Zsofia K., Harrison, Tabitha A., Lin, Yi, Keku, Temitope O., Woods, Michael O., Schafmayer, Clemens, van Guelpen, Bethany, Gallinger, Steven, Hampel, Heather, Berndt, Sonja I., Pharoah, Paul D.P., Lindblom, Annika, Wolk, Alicja, Wu, Anna H., White, Emily, Peters, Ulrike, Drew, David A., Scherer, Dominique, Bermejo, Justo Lorenzo, Williams, Ann C., Relton, Caroline L.
المصدر: Cancer Epidemiology, Biomarkers and Prevention. 30(3):564-575
وصف الملف: electronic
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4Academic Journal
المؤلفون: Morgan, Rhys G, Ridsdale, Jenna, Payne, Megan, Heesom, Kate J, Wilson, Marieangela C, Davidson, Andrew, Greenhough, Alexander, Davies, Sara, Williams, Ann C, Blair, Allison, Waterman, Marian L, Tonks, Alex, Darley, Richard L
المصدر: Haematologica. 104(7)
مصطلحات موضوعية: Pediatric, Childhood Leukemia, Rare Diseases, Pediatric Cancer, Cancer, Hematology, 2.1 Biological and endogenous factors, Aetiology, Biomarkers, Tumor, Cell Nucleus, Gene Expression Regulation, Neoplastic, Humans, Leukemia, Myeloid, Acute, Lymphoid Enhancer-Binding Factor 1, Myelodysplastic Syndromes, Protein Interaction Domains and Motifs, Proteome, RNA, Small Interfering, Transcriptional Activation, Tumor Cells, Cultured, Wnt1 Protein, beta Catenin, Immunology
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/1c36026k
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5Academic Journal
المؤلفون: Holt, Amy K., Najumudeen, Arafath K., Collard, Tracey J., Li, Hao, Millett, Laura M., Hoskin, Ashley J., Legge, Danny N., Mortensson, Eleanor M.H., Flanagan, Dustin J., Jones, Nicholas, Kollareddy, Madhu, Timms, Penny, Hitchings, Matthew D., Cronin, James, Sansom, Owen J., Williams, Ann C., Vincent, Emma E.
وصف الملف: text
Relation: https://eprints.gla.ac.uk/313078/1/313078.pdf; Holt, A. K. et al. (2023) Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition. Cancer and Metabolism , 11(1), 18. (doi:10.1186/s40170-023-00318-y ) (PMID:37858256) (PMCID:PMC10588174)
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6Academic Journal
المؤلفون: Montes Olivas, Sandra, Legge, Danny N, Lund, Abbie, Fletcher, Alexander G., Williams, Ann C, Marucci, Lucia, Homer, Martin E
المصدر: Montes Olivas , S , Legge , D N , Lund , A , Fletcher , A G , Williams , A C , Marucci , L & Homer , M E 2023 , ' In-silico and in-vitro morphometric analysis of intestinal organoids ' , PLoS Computational Biology , vol. 19 , no. 8 , e1011386 . https://doi.org/10.1371/journal.pcbi.1011386
مصطلحات موضوعية: /dk/atira/pure/core/keywords/brissynbio, name=BrisSynBio, /dk/atira/pure/core/keywords/biodesign_SRI, name=Bristol BioDesign Institute, /dk/atira/pure/core/keywords/faculty_of_science/brisengbio, name=BrisEngBio, /dk/atira/pure/core/keywords/engineering_mathematics_research_group, name=Engineering Mathematics Research Group
الاتاحة: https://hdl.handle.net/1983/b6155220-ade7-479b-a18c-61dd2a1beae7
https://research-information.bris.ac.uk/en/publications/b6155220-ade7-479b-a18c-61dd2a1beae7
https://doi.org/10.1371/journal.pcbi.1011386
https://github.com/slmontes/SimpleCryptCount_Project
https://www.biorxiv.org/content/10.1101/2022.12.08.519603v1 -
7Academic Journal
المؤلفون: Hoskin, Ashley J, Holt, Amy K, Legge, Danny N, Collard, Tracey J, Williams, Ann C, Vincent, Emma E
المصدر: Hoskin , A J , Holt , A K , Legge , D N , Collard , T J , Williams , A C & Vincent , E E 2023 , ' Aspirin and the metabolic hallmark of cancer : novel therapeutic opportunities for colorectal cancer ' , Exploration of Targeted Anti-tumor Therapy , vol. 4 , pp. 600–615 . https://doi.org/10.37349/etat.2023.00155
مصطلحات موضوعية: /dk/atira/pure/core/keywords/icep, name=ICEP
Relation: https://research-information.bris.ac.uk/en/publications/10464833-b83f-4a31-9239-a8598fc15b4c
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8Academic Journal
المؤلفون: Holt, Amy K, Collard, Tracey J, Hoskin, Ashley J, Legge, Danny N, Mortensson, Eleanor M H, Kollareddy, Madhu, Timms, Penny, Williams, Ann C, Vincent, Emma E
المصدر: Holt , A K , Collard , T J , Hoskin , A J , Legge , D N , Mortensson , E M H , Kollareddy , M , Timms , P , Williams , A C & Vincent , E E 2023 , ' Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition ' , BMC Cancer & Metabolism . https://doi.org/10.1186/s40170-023-00318-y
مصطلحات موضوعية: /dk/atira/pure/core/keywords/icep, ICEP
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document
الاتاحة: https://hdl.handle.net/1983/74d8743d-36df-4cd8-a509-12b4a7ab44ec
https://research-information.bris.ac.uk/en/publications/74d8743d-36df-4cd8-a509-12b4a7ab44ec
https://doi.org/10.1186/s40170-023-00318-y
https://research-information.bris.ac.uk/ws/files/387028531/Holt_et_al_Aspirin_revised_clean.docx -
9Academic Journal
المؤلفون: Williams, Ann C., Kersten, Thomas A.
المصدر: International Journal of Educational Leadership Preparation. Oct 2013 8(2):94-110.
Peer Reviewed: Y
Page Count: 17
Descriptors: School Business Officials, Change Strategies, Finance Reform, School District Wealth, School District Spending, Money Management, Online Surveys, Interviews, Educational Finance, Financial Problems, Qualitative Research
مصطلحات جغرافية: Illinois
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10Academic Journal
المؤلفون: Parker, Christopher, Chambers, Adam C, Flanagan, Dustin J, Ho, Jasmine Wing Yu, Collard, Tracey J, Ngo, Greg, Baird, Duncan M, Timms, Penny, Morgan, Rhys G, Sansom, Owen J, Williams, Ann C
وصف الملف: application/pdf
Relation: http://sro.sussex.ac.uk/id/eprint/105552/1/1-s2.0-S1568786422000647-main.pdf; Parker, Christopher, Chambers, Adam C, Flanagan, Dustin J, Ho, Jasmine Wing Yu, Collard, Tracey J, Ngo, Greg, Baird, Duncan M, Timms, Penny, Morgan, Rhys G, Sansom, Owen J and Williams, Ann C (2022) BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination. DNA Repair, 115. a103331 1-11. ISSN 1568-7864
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11Academic Journal
المؤلفون: Johnson, Peter A, Menegatti, Sara, Chambers, Adam C, Alibhai, Dominic, Collard, Tracey J, Williams, Ann C, Bayley, Hagan, Perriman, Adam W
المساهمون: UK Research and Innovation, EPSRC & BBSRC Centre for Doctoral Training
المصدر: Biofabrication ; volume 15, issue 1, page 014103 ; ISSN 1758-5082 1758-5090
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12
المؤلفون: Nounu, Aayah, Richmond, Rebecca C., Stewart, Isobel D., Surendran, Praveen, Wareham, Nicholas J., Butterworth, Adam, Weinstein, Stephanie J., Albanes, Demetrius, Baron, John A., Hopper, John L., Figueiredo, Jane C., Newcomb, Polly A., Lindor, Noralane M., Casey, Graham, Platz, Elizabeth A., Marchand, Loïc Le, Ulrich, Cornelia M., Li, Christopher I., van Dujinhoven, Fränzel J. B., Gsur, Andrea, Campbell, Peter T., Moreno, Víctor, Vodicka, Pavel, Vodickova, Ludmila, Amitay, Efrat, Alwers, Elizabeth, Chang-Claude, Jenny, Sakoda, Lori C., Slattery, Martha L., Schoen, Robert E., Gunter, Marc J., Castellví-Bel, Sergi, Kim, Hyeong-Rok, Kweon, Sun-Seog, Chan, Andrew T., Li, Li, Zheng, Wei, Bishop, D. Timothy, Buchanan, Daniel D., Giles, Graham G., Gruber, Stephen B., Rennert, Gad, Stadler, Zsofia K., Harrison, Tabitha A., Lin, Yi, Keku, Temitope O., Woods, Michael O., Schafmayer, Clemens, van Guelpen, Bethany, Gallinger, Steven, Hampel, Heather, Berndt, Sonja I., Pharoah, Paul D. P., Lindblom, Annika, Wolk, Alicja, Wu, Anna H., White, Emily, Peters, Ulrike, Drew, David A., Scherer, Dominique, Bermejo, Justo Lorenzo, Brenner, Hermann, Hoffmeister, Michael, Williams, Ann C., Relton, Caroline L.
المصدر: Nutrients. 13(11)
مصطلحات موضوعية: Aspirin, Colorectal cancer, Mendelian randomization, Salicylic acid
وصف الملف: electronic
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13Academic Journal
المؤلفون: Flanagan, Dustin J., Pentinmikko, Nalle, Luopajärvi, Kalle, Willis, Nicky J., Gilroy, Kathryn, Raven, Alexander P., Mcgarry, Lynn, Englund, Johanna I., Webb, Anna T., Scharaw, Sandra, Nasreddin, Nadia, Hodder, Michael C., Ridgway, Rachel A., Minnee, Emma, Sphyris, Nathalie, Gilchrist, Ella, Najumudeen, Arafath K., Romagnolo, Beatrice, Perret, Christine, Williams, Ann C., Clevers, Hans, Nummela, Pirjo, Lähde, Marianne, Alitalo, Kari, Hietakangas, Ville, Hedley, Ann, Clark, William, Nixon, Colin, Kirschner, Kristina, Jones, E. Yvonne, Ristimäki, Ari, Leedham, Simon J., Fish, Paul V., Vincent, Jean Paul, Katajisto, Pekka, Sansom, Owen J.
المساهمون: Institute of Biotechnology (-2009), University of Helsinki, CAN-PRO - Translational Cancer Medicine Program, Centre of Excellence in Stem Cell Metabolism, Helsinki Institute of Life Science HiLIFE, Institute of Biotechnology, Juha Klefström / Principal Investigator, Research Programs Unit, Department of Pathology, Doctoral Programme in Biomedicine, ATG - Applied Tumor Genomics, Doctoral Programme in Integrative Life Science, HUSLAB, Kari Alitalo / Principal Investigator, Molecular and Integrative Biosciences Research Programme, Biosciences, Nutrient sensing laboratory
مصطلحات موضوعية: STEM-CELLS, BETA-CATENIN, BONE-FORMATION, WNT, MUTATION, HOMEOSTASIS, ACTIVATION, INTESTINE, POLYPOSIS, PATHWAY, Biochemistry, cell and molecular biology, Cancers
وصف الملف: application/pdf
Relation: Acknowledgements We thank the Core Services and Advanced Technologies at the Cancer Research UK Beatson Institute (C596/A17196 and A31287), and particularly the Biological Services Unit, Histology Service and Molecular Technologies; members of the Sansom and Katajisto laboratories for discussions of the data and manuscript; and BRC Oxford for supplying patient material. O.J.S. and his laboratory members were supported by Cancer Research UK (A28223, A21139, A12481 and A17196). D.J.F. and M.C.H. were supported by the UK Medical Research Council (MR/R017247/1 and MR/J50032X/1, respectively). SpecifiCancer CRUK Grand Challenge (C7932/A29055) is funded by Cancer Research UK and the Mark Foundation for Cancer Research. P.K. and his laboratory members were supported by the Academy of Finland Centre of Excellence MetaStem (266869, 304591 and 320185), the ERC Starting Grant 677809, the Swedish Research Council 2018-03078, the Cancerfonden 190634, the Jane and Aatos Erkko Foundation and the Cancer Foundation Finland. N.P. was supported by the Finnish Cultural Foundation, the Biomedicum Helsinki Foundation, the Orion Research Foundation sr and The Paulo Foundation. P.V.F. was supported by Alzheimer’s Research UK and The Francis Crick Institute. The ARUK UCL Drug Discovery Institute receives its core funding from Alzheimer’s Research UK (520909). The Francis Crick Institute receives its core funding from Cancer Research UK (FC001002), the UK Medical Research Council (FC001002) and the Wellcome Trust (FC001002).; Flanagan , D J , Pentinmikko , N , Luopajärvi , K , Willis , N J , Gilroy , K , Raven , A P , Mcgarry , L , Englund , J I , Webb , A T , Scharaw , S , Nasreddin , N , Hodder , M C , Ridgway , R A , Minnee , E , Sphyris , N , Gilchrist , E , Najumudeen , A K , Romagnolo , B , Perret , C , Williams , A C , Clevers , H , Nummela , P , Lähde , M , Alitalo , K , Hietakangas , V , Hedley , A , Clark , W , Nixon , C , Kirschner , K , Jones , E Y , Ristimäki , A , Leedham , S J , Fish , P V , Vincent , J P , Katajisto , P & Sansom , O J 2021 , ' NOTUM from Apc-mutant cells biases clonal competition to initiate cancer ' , Nature , vol. 594 , no. 7863 , pp. 430-435 . https://doi.org/10.1038/s41586-021-03525-z , https://doi.org/10.1038/s41586-021-03525-z; ORCID: /0000-0001-9637-6843/work/97056080; ORCID: /0000-0002-3764-5721/work/124844611; ORCID: /0000-0002-2768-8816/work/125976777; http://hdl.handle.net/10138/337493; 0d60f233-972d-476c-b6db-817ae967b4bb; 85107302159; 000657239300001
الاتاحة: http://hdl.handle.net/10138/337493
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14Academic Journal
المصدر: Flanagan , D J , Williams , A C , Katajisto , P K , Sampson , O J & al. , E 2021 , ' NOTUM from Apc-mutant cells biases clonal competition to initiate cancer ' , Nature , vol. 594 , pp. 430–435 (2021) . https://doi.org/10.1038/s41586-021-03525-z
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/1983/de233e68-5c2a-4ad9-b669-85bfce474adf
https://research-information.bris.ac.uk/en/publications/de233e68-5c2a-4ad9-b669-85bfce474adf
https://doi.org/10.1038/s41586-021-03525-z
https://research-information.bris.ac.uk/ws/files/277609000/Flanagan_et_al._Notum_manuscript_230321_Master_copy_Figs_.pdf
https://research-information.bris.ac.uk/ws/files/316846381/Figs_1_4_Ext._Data_Figs_1_8_160221.pdf -
15Academic Journal
المؤلفون: Dixon, Steven W, Collard, Tracey J, Mortensson, Eleanor M H, Legge, Danny N, Chambers, Adam Christian, Greenhough, Alexander, Creed, Tom J, Williams, Ann C
المصدر: Dixon , S W , Collard , T J , Mortensson , E M H , Legge , D N , Chambers , A C , Greenhough , A , Creed , T J & Williams , A C 2021 , ' 5-aminosalicylic acid inhibits stem cell function in human adenoma derived cells : implications for chemoprophylaxis in colorectal tumorigenesis ' , British Journal of Cancer , vol. 124 , no. 12 , pp. 1959-1969 . https://doi.org/10.1038/s41416-021-01354-5
مصطلحات موضوعية: 5-aminosalicylic acid (5-ASA), colorectal cancer, β-catenin, LGR5
وصف الملف: application/pdf
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16Academic Journal
المؤلفون: Greenhough, Alexander, Nounu, Aayah, Heesom, Kate J., Richmond, Rebecca C., Zheng, Jie, Weinstein, Stephanie J., Albanes, Demetrius, Baron, John A., Hopper, John L., Figueiredo, Jane C., Newcomb, Polly A., Lindor, Noralane M., Casey, Graham, Platz, Elizabeth A., Le Marchand, Loïc, Ulrich, Cornelia M., Li, Christopher I., van Duijnhoven, Fränzel J. B., Gsur, Andrea, Campbell, Peter T., Moreno, Víctor, Vodicka, Pavel, Vodickova, Ludmila, Brenner, Hermann, Chang-Claude, Jenny, Hoffmeister, Michael, Sakoda, Lori C., Slattery, Martha L., Schoen, Robert E., Gunter, Marc J., Castellví-Bel, Sergi, Kim, Hyeong Rok, Kweon, Sun-Seog, Chan, Andrew T., Li, Li, Zheng, Wei, Bishop, D. Timothy, Buchanan, Daniel D., Giles, Graham G., Gruber, Stephen B., Rennert, Gad, Stadler, Zsofia K., Harrison, Tabitha A., Lin, Yi, Keku, Temitope O., Woods, Michael O., Schafmayer, Clemens, Van Guelpen, Bethany, Gallinger, Steven, Hampel, Heather, Berndt, Sonja I., Pharoah, Paul D. P., Lindblom, Annika, Wolk, Alicja, Wu, Anna H., White, Emily, Peters, Ulrike, Drew, David A., Scherer, Dominique, Bermejo, Justo Lorenzo, Williams, Ann C., Relton, Caroline L.
مصطلحات موضوعية: Cancer, Bioinformatics, Epidemiology, Aspirin
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17Academic Journal
المؤلفون: Legge, Danny N, Chambers, Adam C, Parker, Christopher T, Timms, Penny, Collard, Tracey J, Williams, Ann C
المصدر: Legge , D N , Chambers , A C , Parker , C T , Timms , P , Collard , T J & Williams , A C 2020 , ' The role of B-Cell Lymphoma-3 (BCL-3) in enabling the hallmarks of cancer : implications for the treatment of colorectal carcinogenesis ' , Carcinogenesis . https://doi.org/10.1093/carcin/bgaa003
مصطلحات موضوعية: cancer, colorectal cancer, lymphoma, bcl3 protein
وصف الملف: application/pdf
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18Conference
المؤلفون: Dixon, Steven, Mortensson, Eleanor, Creed, Tom, Williams, Ann C
المصدر: Colon and Anorectum ; page A185.2-A186
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19Academic Journal
المؤلفون: Morgan, Rhys G., Ridsdale, Jenna, Payne, Megan, Heesom, Kate J., Wilson, Marieangela C., Davidson, Andrew D., Greenhough, Alexander, Davies, Sara, Williams, Ann C., Blair, Allison, Waterman, Marian L., Tonks, Alex, Darley, Richard L.
مصطلحات موضوعية: acute myeloid leukemia, B-Catenin, LEF-1, Signal transduction, WNT signaling
Relation: https://uwe-repository.worktribe.com/file/854218/1/haematol.2018.202846.full.pdf; https://uwe-repository.worktribe.com/output/854218
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20Academic Journal
المؤلفون: Legge, Danny N., Shephard, Alex P., Collard, Tracey J., Greenhough, Alexander, Chambers, Adam C., Clarkson, Richard W., Paraskeva, Christos, Williams, Ann C.