المؤلفون: Michael J. M. Hitchcock, Erik De Clercq, John C. Martin, William H. Prusoff

المصدر: Antiviral Research. 85:34-38

مصطلحات موضوعية: Pharmacology, Reverse-transcriptase inhibitor, Dideoxynucleosides, Stavudine, HIV Infections, History, 20th Century, Biology, medicine.disease, History, 21st Century, Virology, HIV Reverse Transcriptase, United States, Nucleoside Reverse Transcriptase Inhibitor, Zidovudine, Zalcitabine, Acquired immunodeficiency syndrome (AIDS), medicine, Humans, Reverse Transcriptase Inhibitors, Didanosine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f55872fc25d28250b19ffa55661d99
https://doi.org/10.1016/j.antiviral.2009.10.006

المؤلفون: Wade S. Blair, Arman D Pivazyan, Donald S. Matteson, Rajendra P. Singh, Levente Fabry-Asztalos, William H. Prusoff, Kenny Guo, Brett S. Robinson, Pin-Fang Lin

المصدر: Biochemical Pharmacology. 60:927-936

مصطلحات موضوعية: Boron Compounds, inorganic chemicals, Enzyme complex, Cell Survival, Stereochemistry, medicine.medical_treatment, Drug Resistance, Peptide, Biochemistry, Scissile bond, HIV Protease, HIV-1 protease, Tumor Cells, Cultured, medicine, Humans, Pharmacology, chemistry.chemical_classification, Protease, biology, Tetrapeptide, HIV, HIV Protease Inhibitors, Spectrometry, Fluorescence, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc8e61a6530c03adf9c94468fa0d7ab
https://doi.org/10.1016/s0006-2952(00)00432-9

المؤلفون: Liang Huang, Rocco Carbone, Yikang Si, Kemei Wu, William H. Prusoff, Evelyn M. Birks, Ju-Liang Zhu, Raymond F. Schinazi, Tai-Shun Lin

المصدر: Biochemical Pharmacology. 46:251-255

مصطلحات موضوعية: Cell Survival, Biology, Virus Replication, Antiviral Agents, Biochemistry, Monocytes, chemistry.chemical_compound, medicine, Animals, Humans, Cytotoxic T cell, Cytotoxicity, Vero Cells, Cell Size, Pharmacology, Monocyte, Cell Cycle, Gossypol, Stereoisomerism, Biological activity, Cell cycle, In vitro, medicine.anatomical_structure, chemistry, HIV-1, Vero cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd4bedc114aba961cf202c3be4632d0
https://doi.org/10.1016/0006-2952(93)90411-o

المؤلفون: E. Birks, Tai-Shun Lin, Arman D Pivazyan, A.S. Sun, William H. Prusoff

المصدر: Pharmacology & Therapeutics. 60:315-329

مصطلحات موضوعية: medicine.medical_treatment, Molecular Sequence Data, HIV Infections, Biology, Virus Replication, Antiviral Agents, Virus, Structure-Activity Relationship, chemistry.chemical_compound, Zidovudine, medicine, Animals, Humans, Structure–activity relationship, Protease Inhibitors, Pharmacology (medical), Amino Acid Sequence, Pharmacology, Natural product, Protease, Tetrapeptide, Nucleoside analogue, Hydrocarbons, Halogenated, Gossypol, Stereoisomerism, Pyrimidine Nucleosides, Virology, chemistry, Biochemistry, Drug Design, HIV-1, Nucleoside, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb806430bfe1445670ebefcd5c22cf6a
https://doi.org/10.1016/0163-7258(93)90013-4

المؤلفون: E. Michael August, William H. Prusoff, Lin Tai-Shun, Evelyn M. Birks, Qian He-Ying, Usha A. Thombre

المصدر: Biochemical Pharmacology. 45:223-230

مصطلحات موضوعية: DNA polymerase, Virus Replication, Antiviral Agents, Thymidine Kinase, Biochemistry, Thymidylate kinase, Cell Line, chemistry.chemical_compound, Deoxyadenosine, Idoxuridine, Humans, Phosphorylation, Pharmacology, biology, Uracil, DNA, DNA Polymerase II, Deoxyuridine, HIV Reverse Transcriptase, Reverse transcriptase, Uridine, Kinetics, chemistry, Thymidine kinase, Protein Biosynthesis, HIV-1, biology.protein, RNA, Reverse Transcriptase Inhibitors, Nucleoside-Phosphate Kinase, Thymidine, Cell Division

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e90a9c25e1540dfed9b6326e85e2b30
https://doi.org/10.1016/0006-2952(93)90396-e

المؤلفون: William R. Mancini, Eric J. Gabe, William H. Prusoff, Regina H. Clarke-Katzenburg, Tai Shun Lin, George I. Birnbaum, Mei Zhen Luo, M.‐C. Liu, J. Giziewicz, Yung-Chi Cheng

المصدر: ChemInform. 23

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Hydrochloride, Stereochemistry, Deamination, Nucleic acid, Cytidine, General Medicine, Deoxycytidine kinase, Nucleoside, Deoxycytidine deaminase, ED50

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::17cb5eee31741b4496e26c1b24137e45
https://doi.org/10.1002/chin.199202320

المؤلفون: I. Ghazzouli, Yung-Chi Cheng, J.‐S. Feng, Shen Zy, George I. Birnbaum, V. Brankovan, G.‐D. Hsiung, J. Giziewicz, J.‐H. Yang, Mao-Chin Liu, Tai-Shun Lin, William H. Prusoff

المصدر: ChemInform. 22

مصطلحات موضوعية: chemistry.chemical_compound, Pyrimidine, chemistry, Stereochemistry, Nucleic acid, General Medicine, Crystal structure, Nucleoside, Cytosine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::56b148444654982d3205724ba220b17c
https://doi.org/10.1002/chin.199139238

المؤلفون: William H. Prusoff

المصدر: Nucleosides, Nucleotides and Nucleic Acids. 19:xv-xvii

مصطلحات موضوعية: Genetics, Molecular Medicine, General Medicine, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bd0a4bcb2bc7221651ed6d2f7f1bc983
https://doi.org/10.1080/15257770008032991

المؤلفون: E. Michael August, William H. Prusoff, Tai-Shun Lin, Mao‐Chin Liu, Evelyn M. Birks

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 29:1315-1321

مصطلحات موضوعية: Stereochemistry, Chemistry, Organic Chemistry, Drug Discovery, Human immunodeficiency virus (HIV), medicine, Radiology, Nuclear Medicine and imaging, 3 azido 3 deoxythymidine, medicine.disease_cause, Biochemistry, Spectroscopy, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6cec6cd01f9ffd70653f3b9e8e659ad9
https://doi.org/10.1002/jlcr.2580291208

المؤلفون: Shen Zy, I. Ghazzouli, J. Giziewicz, Mao-Chin Liu, George I. Birnbaum, J.‐H. Yang, Brankovan, Yung-Chi Cheng, Tai-Shun Lin, William H. Prusoff

المصدر: Journal of Medicinal Chemistry. 34:693-701

مصطلحات موضوعية: Chemical Phenomena, Pyrimidine, Stereochemistry, Antineoplastic Agents, Cell Line, Mice, Structure-Activity Relationship, chemistry.chemical_compound, X-Ray Diffraction, Drug Discovery, Side chain, Animals, Molecule, Leukemia L1210, Sarcoma 180, Leukemia P388, Cytarabine, Biological activity, Pyrimidine Nucleosides, In vitro, Chemistry, chemistry, Molecular Medicine, Deoxycytidine, Nucleoside, Cytosine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e394b89472d05c555601dced5b401ca7
https://doi.org/10.1021/jm00106a034

المؤلفون: Maria Elena Marongiu, William H. Prusoff, E.Michael Auoust

المصدر: Biochemical Pharmacology. 39:1523-1528

مصطلحات موضوعية: Cell Survival, Stereochemistry, Cytidine, Biology, Deoxycytidine, Thymidine Kinase, Biochemistry, chemistry.chemical_compound, parasitic diseases, Humans, Amino Acids, Uridine, Cells, Cultured, Pharmacology, Nucleosides, Metabolism, Dideoxynucleosides, Deoxyuridine, Stavudine, chemistry, Thymidine kinase, Thymidine, Nucleoside, Cell Division

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00919b5ad7d286e9f15867e0183e502
https://doi.org/10.1016/0006-2952(90)90516-n

المؤلفون: Yung-Chi Cheng, Alexander A. Krayevsky, William H. Prusoff, Marina K. Kukhanova

المصدر: Current pharmaceutical design. 6(5)

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Nucleoside analogue, Kinase, Anti-HIV Agents, Cell, Nucleosides, Biology, Prodrug, Phosphates, medicine.anatomical_structure, chemistry, Biochemistry, Drug Design, Drug Discovery, medicine, Phosphorylation, Animals, Humans, Nucleotide, Nucleoside, Intracellular, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef7bc411b4add0503c093121a176c14
https://pubmed.ncbi.nlm.nih.gov/10788598

المؤلفون: William H. Prusoff, Ph. D, A Tai-shun Lin, E. Michael August, A Thomas G. Wood, Maria, Elena Marongiu, Ph. D. B

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/f2/49/Yale_J_Biol_Med_1989_Mar-Apr_62(2)_215-225.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.278.3317

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.278.3317

المؤلفون: Byung Ju Kim, Jinhua Zhang, Shenglan Tan, Yung-Chi Cheng, William H. Prusoff, Donald S. Matteson

المصدر: Organic & Biomolecular Chemistry. 10:9349

مصطلحات موضوعية: inorganic chemicals, Molecular Structure, Pyrimidine, Cell Survival, Stereochemistry, Liver Neoplasms, Organic Chemistry, Antineoplastic Agents, Nucleosides, Boronic Acids, Biochemistry, Stereocenter, Hep G2, chemistry.chemical_compound, Pyrimidines, chemistry, Deoxyribose, Cell Line, Tumor, Humans, Molecule, Liberation, Physical and Theoretical Chemistry, Nucleoside, Boronic acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed769ec55e9c719c2aa026144ba7d26
https://doi.org/10.1039/c2ob26756j

المؤلفون: Tai Shun Lin, Yung-Chi Cheng, Eric J. Gabe, M.‐C. Liu, Regina H. Clarke-Katzenburg, J. Giziewicz, Mei Zhen Luo, William R. Mancini, William H. Prusoff, George I. Birnbaum

المصدر: Journal of medicinal chemistry. 34(8)

مصطلحات موضوعية: Chemical Phenomena, Stereochemistry, Hydrochloride, Antineoplastic Agents, Antiviral Agents, Deoxycytidine, chemistry.chemical_compound, Mice, X-Ray Diffraction, In vivo, Drug Discovery, Tumor Cells, Cultured, Animals, Humans, Simplexvirus, Leukemia L1210, Sarcoma 180, Molecular Structure, Chemistry, Leukemia P388, Cytarabine, Cytidine, Biological activity, Nucleosides, Deoxycytidine kinase, Deoxycytidine deaminase, Leukemia, Lymphoid, Deoxyribonucleoside, Molecular Medicine, Female, Crystallization, Nucleoside

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3872a61547d6ebb668ba8fbb95b00548
https://pubmed.ncbi.nlm.nih.gov/1652024

المؤلفون: Sue A. Keilbaugh, Melvin V. Simpson, William H. Prusoff

المصدر: Biochemical pharmacology. 42(1)

مصطلحات موضوعية: Mitochondrial DNA, Neurite, Cell, PC12 cell line, Biology, Mitochondrion, Biochemistry, chemistry.chemical_compound, Zidovudine, Bone Marrow, medicine, Tumor Cells, Cultured, Animals, Cell Line, Transformed, Pharmacology, Dose-Response Relationship, Drug, Zalcitabine, DNA replication, Peripheral Nervous System Diseases, Virology, Molecular biology, Axons, Dideoxynucleosides, Didanosine, Stavudine, medicine.anatomical_structure, chemistry, DNA, Cell Division, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6488403f80fe6b30282536a7c9a6379
https://pubmed.ncbi.nlm.nih.gov/1648918

المؤلفون: Marcia L. Zucker, Jen-Fu Chiu, Tai-Shun Lin, Dao-pei Huang, William H. Prusoff, Xiao-kun Zhang

المصدر: Cancer communications. 3(4)

مصطلحات موضوعية: Cancer Research, Nitrosourea, Time Factors, Transcription, Genetic, Cell, Genes, myc, Antineoplastic Agents, Biology, chemistry.chemical_compound, Mice, Proto-Oncogene Proteins c-myb, Proto-Oncogene Proteins, Gene expression, Proto-Oncogenes, medicine, Tumor Cells, Cultured, Animals, Leukemia L1210, Messenger RNA, Oncogene, Dose-Response Relationship, Drug, DNA, Blotting, Northern, Molecular biology, Actins, Dideoxynucleosides, Gene Expression Regulation, Neoplastic, Blotting, Southern, medicine.anatomical_structure, chemistry, Cell culture, L1210 cells, RNA, Thymidine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5805e57199f40b73fab556d1fe4835e6
https://pubmed.ncbi.nlm.nih.gov/1709036

المؤلفون: Maria Elena Marongiu, William H. Prusoff, Thomas G. Wood

المصدر: Biochemical pharmacology. 41(3)

مصطلحات موضوعية: Pharmacology, Differential centrifugation, Density gradient, Ultraviolet Rays, viruses, Biology, medicine.disease_cause, Biochemistry, Molecular biology, Virus, chemistry.chemical_compound, Herpes simplex virus, chemistry, Idoxuridine, DNA, Viral, Nucleic acid, Ultraviolet light, medicine, Simplexvirus, Irradiation, DNA, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f960acdd633ee6b90bcd13a9301500e
https://pubmed.ncbi.nlm.nih.gov/1847286

المؤلفون: Tai-Shun Lin, V. Brankovan, E. M. August, Shen Zy, William H. Prusoff, H. Yang, Ismail Ghazzouli

المصدر: ChemInform. 21

مصطلحات موضوعية: Stereochemistry, Chemistry, Human immunodeficiency virus (HIV), medicine, General Medicine, 3'-azido-2'-3'-dideoxyuridine, 3 azido 3 deoxythymidine, medicine.disease_cause

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0513b75a9f4d5555a7a5a8e61ffd7524
https://doi.org/10.1002/chin.199002328

المؤلفون: William H. Prusoff, U. Patel‐Thombre

المصدر: Annals of the New York Academy of Sciences. 616:591-592

مصطلحات موضوعية: History and Philosophy of Science, Chemistry, General Neuroscience, Human immunodeficiency virus (HIV), medicine, medicine.disease_cause, Virology, General Biochemistry, Genetics and Molecular Biology, Ene reaction, Reverse transcriptase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d691eef4dc2652f8d48a34c21012f98c
https://doi.org/10.1111/j.1749-6632.1990.tb17901.x