نتائج البحث - "William, Samia"

1

Academic Journal

To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

المصدر: Zheng , Y , Schroeder , S , Kanev , G K , Botros , S S , William , S , Sabra , A N A , Maes , L , Caljon , G , Gil , C , Martinez , A , Salado , I G , Augustyns , K , Edink , E , Sijm , M , de Heuvel , E , de Esch , I J P , van der Meer , T , Siderius , M , Sterk , G J , Brown , D & Leurs , R 2023 , ' To ....

مصطلحات موضوعية: drug target, phosphodiesterase, Schistosoma mansoni, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

Relation: https://research.vu.nl/en/publications/018c77d9-2184-4776-a46d-73d48e1bea16

الاتاحة: https://research.vu.nl/en/publications/018c77d9-2184-4776-a46d-73d48e1bea16
https://doi.org/10.3390/ijms24076817
https://hdl.handle.net/1871.1/018c77d9-2184-4776-a46d-73d48e1bea16
http://www.scopus.com/inward/record.url?scp=85152305942&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85152305942&partnerID=8YFLogxK

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2

Academic Journal

Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools

المؤلفون: Sebastián-Pérez, Víctor, García-Rubia, Alfonso, Seif el-Din, Sayed H., Sabra, Abdel-Nasser A., El-Lakkany, Naglaa M., William, Samia, Blundell, Tom L., Maes, Louis, Martínez, Ana, Campillo, Nuria E., Botros, Sanaa S., Gil, Carmen

المساهمون: European Commission, Ministerio de Educación, Cultura y Deporte (España), Sebastián-Pérez, Víctor, García-Rubia, Alfonso, Seif el-Din, Sayed H., El-Lakkany, Naglaa M., William, Samia, Maes, Louis /, Martínez, Ana, Campillo, Nuria E., Gil, Carmen

مصطلحات موضوعية: Drug discovery, Quinazoline, Schistosoma mansoni, Target deconvolution

Relation: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/EC/FP7/602666; Publisher's version; https://doi.org/10.1080/14756366.2020.1712595; Sí; J Enzyme Inhib Med Chem 35(1):511-523 (2020); http://hdl.handle.net/10261/200761; http://dx.doi.org/10.13039/501100000780; http://dx.doi.org/10.13039/501100003176

الاتاحة: http://hdl.handle.net/10261/200761
https://doi.org/10.1080/14756366.2020.1712595
https://doi.org/10.13039/501100000780
https://doi.org/10.13039/501100003176

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3

Academic Journal

Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages

المؤلفون: Munday, Jane C., Kunz, Stefan, Kalejaiye, Titilola D., Siderius, Marco, Schroeder, Susanne, Paape, Daniel, Alghamdi, Ali H., Abbasi, Zainab, Huang, Sheng Xiang, Donachie, Anne Marie, William, Samia, Sabra, Abdel Nasser, Sterk, Geert Jan, Botros, Sanaa S., Brown, David G., Hoffman, Charles S., Leurs, Rob, de Koning, Harry P.

المصدر: Munday , J C , Kunz , S , Kalejaiye , T D , Siderius , M , Schroeder , S , Paape , D , Alghamdi , A H , Abbasi , Z , Huang , S X , Donachie , A M , William , S , Sabra , A N , Sterk , G J , Botros , S S , Brown , D G , Hoffman , C S , Leurs , R & de Koning , H P 2020 , ' Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian ....

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

الاتاحة: https://research.vu.nl/en/publications/9a78b6f8-f727-4d9e-8457-c79da169990b
https://doi.org/10.1371/journal.pntd.0008447
https://hdl.handle.net/1871.1/9a78b6f8-f727-4d9e-8457-c79da169990b
http://www.scopus.com/inward/record.url?scp=85089709190&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85089709190&partnerID=8YFLogxK

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4

Electronic Resource

To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

مصطلحات الفهرس: Schistosoma mansoni, Phosphodiesterase, Drug target, artículo

URL: http://hdl.handle.net/10261/308076
https://doi.org/10.3390/ijms24076817
Publisher's version
https://doi.org/10.3390/ijms24076817
Sí
info:eu-repo/grantAgreement/EC/FP7/602666

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5

Academic Journal

Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity

المصدر: Botros , S S , William , S , Sabra , A N A , El-Lakkany , N M , Seif el-Din , S H , García-Rubia , A , Sebastián-Pérez , V , Blaazer , A R , de Heuvel , E , Sijm , M , Zheng , Y , Salado , I G , Munday , J C , Maes , L , de Esch , I J P , Sterk , G J , Augustyns , K , Leurs , R , Gil , C & De Koning , H P 2019 , ' Screening ....

مصطلحات موضوعية: In vitro drug screening, Mouse model, Phosphodiesterase, Praziquantel, Schistosoma mansoni, Schistosomiasis, Worm killing

الاتاحة: https://research.vu.nl/en/publications/1a2d46cd-4c43-4839-aca6-0d9465891290
https://doi.org/10.1016/j.ijpddr.2019.01.001
https://hdl.handle.net/1871.1/1a2d46cd-4c43-4839-aca6-0d9465891290
http://www.scopus.com/inward/record.url?scp=85060094840&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85060094840&partnerID=8YFLogxK
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350229

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6

Academic Journal

A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection

المؤلفون: Radwan, Amr, El-Lakkany, Naglaa M., William, Samia, El-Feky, Gina S., Al-Shorbagy, Muhammad Y., Saleh, Samira, Botros, Sanaa

المصدر: Parasites & Vectors ; volume 12, issue 1 ; ISSN 1756-3305

الاتاحة: http://dx.doi.org/10.1186/s13071-019-3563-z
http://link.springer.com/content/pdf/10.1186/s13071-019-3563-z.pdf
http://link.springer.com/article/10.1186/s13071-019-3563-z/fulltext.html

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7

Academic Journal

Itraconazole, a cytochrome P450 inhibitor, enhanced the efficacy of praziquantel against Schistosoma mansoni infection and alleviated liver injury in mice

المؤلفون: Sabra, Abdel-Nasser A., Salem, Maha B., William, Samia, Hammam, Olfat A., El-Lakkany, Naglaa M.

المساهمون: Theodor Bilharz Research Institute

المصدر: Experimental Parasitology ; volume 239, page 108293 ; ISSN 0014-4894

الاتاحة: http://dx.doi.org/10.1016/j.exppara.2022.108293
https://api.elsevier.com/content/article/PII:S001448942200087X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S001448942200087X?httpAccept=text/plain

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8

Academic Journal

Schistosomicidal and hepatoprotective activity of gamma-aminobutyric acid (GABA) alone or combined with praziquantel against Schistosoma mansoni infection in murine model

المؤلفون: Fahmy, Azza Moustafa, William, Samia, Hegab, Amany, TM, Diab

المصدر: Experimental Parasitology ; volume 238, page 108260 ; ISSN 0014-4894

الاتاحة: http://dx.doi.org/10.1016/j.exppara.2022.108260
https://api.elsevier.com/content/article/PII:S0014489422000546?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0014489422000546?httpAccept=text/plain

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9

Academic Journal

MCR Synthesis of Praziquantel Derivatives

المؤلفون: Liu, Haixia, William, Samia, Herdtweck, Eberhardt, Botros, Sanaa, Dömling, Alexander

المصدر: Chemical Biology & Drug Design ; volume 79, issue 4, page 470-477 ; ISSN 1747-0277 1747-0285

الاتاحة: http://dx.doi.org/10.1111/j.1747-0285.2011.01288.x
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1747-0285.2011.01288.x
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1747-0285.2011.01288.x

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10

Academic Journal

Further assessment of Mirazid as antischistosomal drug in experimental schistosomiasis hematobium

المؤلفون: Ramzy, Fatem, Mahmoud, Soheir, William, Samia

المصدر: Pharmaceutical Biology ; volume 48, issue 7, page 775-779 ; ISSN 1388-0209 1744-5116

الاتاحة: http://dx.doi.org/10.3109/13880200903074635
http://www.tandfonline.com/doi/pdf/10.3109/13880200903074635

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11

Academic Journal

Antischistosomal Activity of Hexadecyloxypropyl Cyclic 9-( S )-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine and Other Alkoxyalkyl Esters of Acyclic Nucleoside Phosphonates Assessed by Schistosome Worm Killing In Vitro

المؤلفون: Botros, Sanaa S., William, Samia, Beadle, James R., Valiaeva, Nadejda, Hostetler, Karl Y.

المصدر: Antimicrobial Agents and Chemotherapy ; volume 53, issue 12, page 5284-5287 ; ISSN 0066-4804 1098-6596

الاتاحة: http://dx.doi.org/10.1128/aac.00840-09
https://journals.asm.org/doi/pdf/10.1128/AAC.00840-09

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12

Academic Journal

The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo

المؤلفون: Botros, Sanaa S., El-Lakkany, Naglaa M., Seif el-Din, Sayed H., William, Samia, Sabra, Abdel-Nasser, Hammam, Olfat A., De Koning, Harry P.

Relation: Botros, S. S., El-Lakkany, N. M., Seif el-Din, S. H., William, S., Sabra, A.-N., Hammam, O. A. and De Koning, H. P. (2020) The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo. Experimental Parasitology , 208, 107793. (doi:10.1016/j.exppara.2019.107793 ) (PMID:31711973)

الاتاحة: http://eprints.gla.ac.uk/202946/

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