المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/journal_contribution/Supporting_information_contains_additional_information_on_the_SARS-CoV-2_adaptation_in_VeroE6_expands_on_lack_of_mutations_in_the_presence_on_RDV_the_pressure_to_evolve_with_greater_focus_on_the_Spike_/16638042

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s014

المؤلفون: Suzannah J. Rihn (10196153), Andres Merits (191446), Siddharth Bakshi (338420), Matthew L. Turnbull (10196156), Arthur Wickenhagen (9344984), Akira J. T. Alexander (10196159), Carla Baillie (10196162), Benjamin Brennan (522804), Fiona Brown (1432693), Kirstyn Brunker (181178), Steven R. Bryden (10196165), Kerry A. Burness (10196168), Stephen Carmichael (10196171), Sarah J. Cole (10196174), Vanessa M. Cowton (5455085), Paul Davies (264924), Chris Davis (647632), Giuditta De Lorenzo (552196), Claire L. Donald (7255148), Mark Dorward (10196177), James I. Dunlop (4861777), Matthew Elliott (2700826), Mazigh Fares (8528505), Ana da Silva Filipe (5849153), Joseph R. Freitas (10196180), Wilhelm Furnon (10196183), Rommel J. Gestuveo (10196186), Anna Geyer (10196189), Daniel Giesel (10196192), Daniel M. Goldfarb (10196195), Nicola Goodman (10196198), Rory Gunson (612918), C. James Hastie (2453785), Vanessa Herder (289722), Joseph Hughes (42279), Clare Johnson (4399042), Natasha Johnson (10196201), Alain Kohl (252931), Karen Kerr (3393170), Hannah Leech (10196204), Laura Sandra Lello (8911877), Kathy Li (8978138), Gauthier Lieber (10196207), Xiang Liu (119470), Rajendra Lingala (10196210), Colin Loney (418948), Daniel Mair (5849150), Marion J. McElwee (10196213), Steven McFarlane (205895), Jenna Nichols (10196216), Kyriaki Nomikou (177223), Anne Orr (205891), Richard J. Orton (7832015), Massimo Palmarini (81656), Yasmin A. Parr (10196219), Rute Maria Pinto (10196222), Samantha Raggett (10196225), Elaine Reid (10196228), David L. Robertson (8893238), Jamie Royle (10196231), Natalia Cameron-Ruiz (10196234), James G. Shepherd (10196237), Katherine Smollett (6499391), Douglas G. Stewart (10196240), Meredith Stewart (199689), Elena Sugrue (550105), Agnieszka M. Szemiel (10196243), Aislynn Taggart (10196246), Emma C. Thomson (10196249), Lily Tong (5904683), Leah S. Torrie (325205), Rachel Toth (141271), Margus Varjak (191439), Sainan Wang (713604), Stuart G. Wilkinson (10196252), Paul G. Wyatt (473658), Eva Zusinaite (7461902), Dario R. Alessi (157506), Arvind H. Patel (10196255), Ali Zaid (10196258), Sam J. Wilson (9344990), Suresh Mahalingam (176075)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Biotechnology, Mental Health, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Coronavirus Disease 2019, SARS-CoV -2 research, advance COVID -19 vaccine design, genetics system, plasmid SARS-CoV -2, COVID -19 research, Severe Acute Respiratory Syndrome C., TMPRSS 2 expression, plasmid DNA-launched SARS-CoV -2, ORF 10 protein, SARS-CoV -2 toolkit, SARS-CoV -2 antibodies

Relation: https://figshare.com/articles/journal_contribution/Cross-reactivity_of_coronavirus_nucleocapsid_N_and_envelope_E_proteins_/14115998

الاتاحة: https://doi.org/10.1371/journal.pbio.3001091.s004

المؤلفون: Suzannah J. Rihn (10196153), Andres Merits (191446), Siddharth Bakshi (338420), Matthew L. Turnbull (10196156), Arthur Wickenhagen (9344984), Akira J. T. Alexander (10196159), Carla Baillie (10196162), Benjamin Brennan (522804), Fiona Brown (1432693), Kirstyn Brunker (181178), Steven R. Bryden (10196165), Kerry A. Burness (10196168), Stephen Carmichael (10196171), Sarah J. Cole (10196174), Vanessa M. Cowton (5455085), Paul Davies (264924), Chris Davis (647632), Giuditta De Lorenzo (552196), Claire L. Donald (7255148), Mark Dorward (10196177), James I. Dunlop (4861777), Matthew Elliott (2700826), Mazigh Fares (8528505), Ana da Silva Filipe (5849153), Joseph R. Freitas (10196180), Wilhelm Furnon (10196183), Rommel J. Gestuveo (10196186), Anna Geyer (10196189), Daniel Giesel (10196192), Daniel M. Goldfarb (10196195), Nicola Goodman (10196198), Rory Gunson (612918), C. James Hastie (2453785), Vanessa Herder (289722), Joseph Hughes (42279), Clare Johnson (4399042), Natasha Johnson (10196201), Alain Kohl (252931), Karen Kerr (3393170), Hannah Leech (10196204), Laura Sandra Lello (8911877), Kathy Li (8978138), Gauthier Lieber (10196207), Xiang Liu (119470), Rajendra Lingala (10196210), Colin Loney (418948), Daniel Mair (5849150), Marion J. McElwee (10196213), Steven McFarlane (205895), Jenna Nichols (10196216), Kyriaki Nomikou (177223), Anne Orr (205891), Richard J. Orton (7832015), Massimo Palmarini (81656), Yasmin A. Parr (10196219), Rute Maria Pinto (10196222), Samantha Raggett (10196225), Elaine Reid (10196228), David L. Robertson (8893238), Jamie Royle (10196231), Natalia Cameron-Ruiz (10196234), James G. Shepherd (10196237), Katherine Smollett (6499391), Douglas G. Stewart (10196240), Meredith Stewart (199689), Elena Sugrue (550105), Agnieszka M. Szemiel (10196243), Aislynn Taggart (10196246), Emma C. Thomson (10196249), Lily Tong (5904683), Leah S. Torrie (325205), Rachel Toth (141271), Margus Varjak (191439), Sainan Wang (713604), Stuart G. Wilkinson (10196252), Paul G. Wyatt (473658), Eva Zusinaite (7461902), Dario R. Alessi (157506), Arvind H. Patel (10196255), Ali Zaid (10196258), Sam J. Wilson (9344990), Suresh Mahalingam (176075)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Biotechnology, Mental Health, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Coronavirus Disease 2019, SARS-CoV -2 research, advance COVID -19 vaccine design, genetics system, plasmid SARS-CoV -2, COVID -19 research, Severe Acute Respiratory Syndrome C., TMPRSS 2 expression, plasmid DNA-launched SARS-CoV -2, ORF 10 protein, SARS-CoV -2 toolkit, SARS-CoV -2 antibodies

Relation: https://figshare.com/articles/journal_contribution/Extended_Materials_and_methods_/14116013

الاتاحة: https://doi.org/10.1371/journal.pbio.3001091.s007

المؤلفون: Suzannah J. Rihn (10196153), Andres Merits (191446), Siddharth Bakshi (338420), Matthew L. Turnbull (10196156), Arthur Wickenhagen (9344984), Akira J. T. Alexander (10196159), Carla Baillie (10196162), Benjamin Brennan (522804), Fiona Brown (1432693), Kirstyn Brunker (181178), Steven R. Bryden (10196165), Kerry A. Burness (10196168), Stephen Carmichael (10196171), Sarah J. Cole (10196174), Vanessa M. Cowton (5455085), Paul Davies (264924), Chris Davis (647632), Giuditta De Lorenzo (552196), Claire L. Donald (7255148), Mark Dorward (10196177), James I. Dunlop (4861777), Matthew Elliott (2700826), Mazigh Fares (8528505), Ana da Silva Filipe (5849153), Joseph R. Freitas (10196180), Wilhelm Furnon (10196183), Rommel J. Gestuveo (10196186), Anna Geyer (10196189), Daniel Giesel (10196192), Daniel M. Goldfarb (10196195), Nicola Goodman (10196198), Rory Gunson (612918), C. James Hastie (2453785), Vanessa Herder (289722), Joseph Hughes (42279), Clare Johnson (4399042), Natasha Johnson (10196201), Alain Kohl (252931), Karen Kerr (3393170), Hannah Leech (10196204), Laura Sandra Lello (8911877), Kathy Li (8978138), Gauthier Lieber (10196207), Xiang Liu (119470), Rajendra Lingala (10196210), Colin Loney (418948), Daniel Mair (5849150), Marion J. McElwee (10196213), Steven McFarlane (205895), Jenna Nichols (10196216), Kyriaki Nomikou (177223), Anne Orr (205891), Richard J. Orton (7832015), Massimo Palmarini (81656), Yasmin A. Parr (10196219), Rute Maria Pinto (10196222), Samantha Raggett (10196225), Elaine Reid (10196228), David L. Robertson (8893238), Jamie Royle (10196231), Natalia Cameron-Ruiz (10196234), James G. Shepherd (10196237), Katherine Smollett (6499391), Douglas G. Stewart (10196240), Meredith Stewart (199689), Elena Sugrue (550105), Agnieszka M. Szemiel (10196243), Aislynn Taggart (10196246), Emma C. Thomson (10196249), Lily Tong (5904683), Leah S. Torrie (325205), Rachel Toth (141271), Margus Varjak (191439), Sainan Wang (713604), Stuart G. Wilkinson (10196252), Paul G. Wyatt (473658), Eva Zusinaite (7461902), Dario R. Alessi (157506), Arvind H. Patel (10196255), Ali Zaid (10196258), Sam J. Wilson (9344990), Suresh Mahalingam (176075)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Biotechnology, Mental Health, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Coronavirus Disease 2019, SARS-CoV -2 research, advance COVID -19 vaccine design, genetics system, plasmid SARS-CoV -2, COVID -19 research, Severe Acute Respiratory Syndrome C., TMPRSS 2 expression, plasmid DNA-launched SARS-CoV -2, ORF 10 protein, SARS-CoV -2 toolkit, SARS-CoV -2 antibodies

Relation: https://figshare.com/articles/journal_contribution/Reagents_and_resources_/14116019

الاتاحة: https://doi.org/10.1371/journal.pbio.3001091.s009

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/figure/RDV_mixed_array_inhibitor_screen_with_SARS-CoV-2_sub_Engl2_sub_in_VeroE6_cells_/16637988

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s001

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/figure/Adaptation_of_SARS-CoV-2_sub_Engl2_sub_to_VeroE6_and_selection_of_decreased_RDV_sensitivity_/16637991

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s002

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/figure/Antiviral_activity_of_RDV_and_EIDD2801_in_Vero_ACE-2_against_three_continually_passaged_populations_and_the_input_SARS-CoV-2_sub_Engl2_sub_/16637994

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s003

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/figure/S4_Fig_-/16637997

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s004

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/figure/Antiviral_activity_of_RDV_and_EIDD2801against_NSP6_and_NSP12_mutant_viruses_/16638003

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s005

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/figure/Sequence_analysis_of_continually_RDV_selected_SARS-CoV-2_sub_Engl2_sub_/16638006

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s006

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/figure/Schematic_layout_of_96-well_plate_clearance_assay_for_drug_screen_/16638012

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s007

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/dataset/RDV_and_EIDD2801_EC_sub_50_sub_and_fold-change_in_VeroE6-ACE2-TMPRSS2_/16638015

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s008

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/dataset/dN_dS_ratio_for_all_SARS-CoV-2_open_reading_frames_ORF1ab_and_Spike_for_the_i_in_vitro_i_continually_passaged_SARS-CoV-2_/16638021

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s009

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/dataset/Excel_sheet_summarizing_of_mutations_across_different_continually_passaged_virus_populations_in_comparison_to_SARS-CoV-2_sub_Wuhan-1_sub_MN908947_and_SARS-CoV-2_sub_Engl2_sub_/16638024

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s010

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/dataset/Conservation_of_NSP12_E802_and_NSP6_I168_in_coronaviruses_/16638030

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s011

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/dataset/SARS-CoV-2_spike_mutation_arising_in_vitro_are_prevalence_in_the_circulating_sequences_/16638033

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s012

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/dataset/GISAID_Acknowledgements_/16638039

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.s013

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/figure/Continuous_passage_of_SARS-CoV-2_sub_Engl2_sub_in_RDV_selects_for_partial_resistant_populations_/16638048

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.g001

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/figure/Common_mutations_in_partial_RDV_resistance_populations_/16638051

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.g002

المؤلفون: Agnieszka M. Szemiel (10196243), Andres Merits (191446), Richard J. Orton (7832015), Oscar A. MacLean (10297450), Rute Maria Pinto (10196222), Arthur Wickenhagen (9344984), Gauthier Lieber (10196207), Matthew L. Turnbull (10196156), Sainan Wang (713604), Wilhelm Furnon (10196183), Nicolas M. Suarez (11450466), Daniel Mair (5849150), Ana da Silva Filipe (5849153), Brian J. Willett (11450469), Sam J. Wilson (9344990), Arvind H. Patel (10196255), Emma C. Thomson (10196249), Massimo Palmarini (81656), Alain Kohl (252931), Meredith E. Stewart (11450472)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Evolutionary Biology, Ecology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, residue conserved among, e ., h69, div >< p, alternate nucleoside analogue, affect virus fitness, affect viral replication, resistant viral populations, serially passaging sars, reports identifying sars, globally circulating sars, decreasing rdv sensitivity, dependent rna polymerase, corresponding sites identified, nsp12 e802d mutation, 2 rdv resistance, single mutation, resistant mutants, emerging sars, rdv )

Relation: https://figshare.com/articles/figure/NSP12_E802_mutation_recapitulates_change_in_RDV_susceptibility_/16638054

الاتاحة: https://doi.org/10.1371/journal.ppat.1009929.g003