يعرض 1 - 7 نتائج من 7 نتيجة بحث عن '"Whittamore, Paul R. O."', وقت الاستعلام: 0.35s تنقيح النتائج
  1. 1
    Academic Journal
    Identification and optimisation of 3,3-dimethyl-azetidin-2-ones as potent and selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)

    المؤلفون: McCoull, William, Augustin, Martin, Blake, Caroline, Ertan, Anne, Kilgour, Elaine, Krapp, Stephan, Moore, Jane E., Newcombe, Nicholas J., Packer, Martin J., Rees, Amanda, Revill, John, Scott, James S., Selmi, Nidhal, Gerhardt, Stefan, Ogg, Derek J., Steinbacher, Stefan, Whittamore, Paul R. O.

    المصدر: Med. Chem. Commun. ; volume 5, issue 1, page 57-63 ; ISSN 2040-2503 2040-2511

    الاتاحة: http://dx.doi.org/10.1039/c3md00234a
    http://pubs.rsc.org/en/content/articlepdf/2014/MD/C3MD00234A

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  2. 2
    Academic Journal
    Reduction of acyl glucuronidation in a series of acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors: the discovery of AZD6925

    المؤلفون: Scott, James S., Barton, Peter, Bennett, Stuart N. L., deSchoolmeester, Joanne, Godfrey, Linda, Kilgour, Elaine, Mayers, Rachel M., Packer, Martin J., Rees, Amanda, Schofield, Paul, Selmi, Nidhal, Swales, John G., Whittamore, Paul R. O.

    المصدر: MedChemComm ; volume 3, issue 10, page 1264 ; ISSN 2040-2503 2040-2511

    الاتاحة: http://dx.doi.org/10.1039/c2md20154b
    http://pubs.rsc.org/en/content/articlepdf/2012/MD/C2MD20154B

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  3. 3
    Academic Journal
    Discovery of a Potent, Selective, and Orally Bioavailable Acidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor: Discovery of 2-[(3 S)-1-[5-(Cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic Acid (AZD4017)

    المؤلفون: Scott, James S., Bowker, Suzanne S., deSchoolmeester, Joanne, Gerhardt, Stefan, Hargreaves, David, Kilgour, Elaine, Lloyd, Adele, Mayers, Rachel M., McCoull, William, Newcombe, Nicholas J., Ogg, Derek, Packer, Martin J., Rees, Amanda, Revill, John, Schofield, Paul, Selmi, Nidhal, Swales, John G., Whittamore, Paul R. O.

    المصدر: Journal of Medicinal Chemistry ; volume 55, issue 12, page 5951-5964 ; ISSN 0022-2623 1520-4804

    الاتاحة: http://dx.doi.org/10.1021/jm300592r
    https://pubs.acs.org/doi/pdf/10.1021/jm300592r

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  4. 4
    Academic Journal
    Novel Acidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor with Reduced Acyl Glucuronide Liability: The Discovery of 4-[4-(2-Adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic Acid (AZD8329)

    المؤلفون: Scott, James S., deSchoolmeester, Joanne, Kilgour, Elaine, Mayers, Rachel M., Packer, Martin J., Hargreaves, David, Gerhardt, Stefan, Ogg, Derek J., Rees, Amanda, Selmi, Nidhal, Stocker, Andrew, Swales, John G., Whittamore, Paul R. O.

    المصدر: Journal of Medicinal Chemistry ; volume 55, issue 22, page 10136-10147 ; ISSN 0022-2623 1520-4804

    الاتاحة: http://dx.doi.org/10.1021/jm301252n
    https://pubs.acs.org/doi/pdf/10.1021/jm301252n

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  5. 5
    Academic Journal
    A Novel Approach to Dual-Acting Thromboxane Receptor Antagonist/Synthase Inhibitors Based on the Link of 1,3-Dioxane-Thromboxane Receptor Antagonists and -Thromboxane Synthase Inhibitors

    المؤلفون: Ackerley, Norman, Brewster, Andrew G., Brown, George R., Clarke, David S., Foubister, Alan J., Griffin, Stephen J., Hudson, Julian A., Smithers, Michael J., Whittamore, Paul R. O.

    المصدر: Journal of Medicinal Chemistry ; volume 38, issue 10, page 1608-1628 ; ISSN 0022-2623 1520-4804

    الاتاحة: http://dx.doi.org/10.1021/jm00010a005
    https://pubs.acs.org/doi/pdf/10.1021/jm00010a005

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  6. 6
    Academic Journal
    Discovery of a Potent,Selective, and Orally BioavailableAcidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1)Inhibitor: Discovery of...

    المؤلفون: Scott, James S., Bowker, Suzanne S., deSchoolmeester, Joanne, Gerhardt, Stefan, Hargreaves, David, Kilgour, Elaine, Lloyd, Adele, Mayers, Rachel M., McCoull, William, Newcombe, Nicholas J., Ogg, Derek, Packer, Martin J., Rees, Amanda, Revill, John, Schofield, Paul, Selmi, Nidhal, Swales, John G., Whittamore, Paul R. O.

    المصدر: Journal of Medicinal Chemistry; Jun2012, Vol. 55 Issue 12, p5951-5964, 14p


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  7. 7
    Academic Journal
    Hydroxyversicolorone: synthesis and incorporation of a new intermediate in aflatoxin biosynthesis

    المؤلفون: Townsend, Craig A., Whittamore, Paul R. O., Brobst, Susan W.

    المصدر: Journal of the Chemical Society, Chemical Communications ; issue 11, page 726 ; ISSN 0022-4936

    الاتاحة: http://dx.doi.org/10.1039/c39880000726
    http://pubs.rsc.org/en/content/articlepdf/1988/C3/C39880000726

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