المؤلفون: Haas, Kelsey M, McGregor, Michael J, Bouhaddou, Mehdi, Polacco, Benjamin J, Kim, Eun-Young, Nguyen, Thong T, Newton, Billy W, Urbanowski, Matthew, Kim, Heejin, Williams, Michael AP, Rezelj, Veronica V, Hardy, Alexandra, Fossati, Andrea, Stevenson, Erica J, Sukerman, Ellie, Kim, Tiffany, Penugonda, Sudhir, Moreno, Elena, Braberg, Hannes, Zhou, Yuan, Metreveli, Giorgi, Harjai, Bhavya, Tummino, Tia A, Melnyk, James E, Soucheray, Margaret, Batra, Jyoti, Pache, Lars, Martin-Sancho, Laura, Carlson-Stevermer, Jared, Jureka, Alexander S, Basler, Christopher F, Shokat, Kevan M, Shoichet, Brian K, Shriver, Leah P, Johnson, Jeffrey R, Shaw, Megan L, Chanda, Sumit K, Roden, Dan M, Carter, Tonia C, Kottyan, Leah C, Chisholm, Rex L, Pacheco, Jennifer A, Smith, Maureen E, Schrodi, Steven J, Albrecht, Randy A, Vignuzzi, Marco, Zuliani-Alvarez, Lorena, Swaney, Danielle L, Eckhardt, Manon, Wolinsky, Steven M, White, Kris M, Hultquist, Judd F, Kaake, Robyn M, García-Sastre, Adolfo, Krogan, Nevan J

المصدر: Nature Communications. 14(1)

مصطلحات موضوعية: Microbiology, Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Influenza, Biotechnology, Genetics, Lung, Biodefense, Pneumonia & Influenza, Emerging Infectious Diseases, Infectious Diseases, 2.1 Biological and endogenous factors, 2.2 Factors relating to the physical environment, Infection, Humans, Influenza A virus, Influenza, Human, Influenza A Virus, H5N1 Subtype, Influenza A Virus, H3N2 Subtype, Proteomics, Virus Replication, COVID-19, SARS-CoV-2, Antiviral Agents, Host-Pathogen Interactions

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5h41d3sv
https://escholarship.org/content/qt5h41d3sv/qt5h41d3sv.pdf

المؤلفون: Varona, Jose F, Landete, Pedro, Lopez-Martin, Jose A, Estrada, Vicente, Paredes, Roger, Guisado-Vasco, Pablo, de Orueta, Lucia Fernandez, Torralba, Miguel, Fortun, Jesus, Vates, Roberto, Barberan, Jose, Clotet, Bonaventura, Ancochea, Julio, Carnevali, Daniel, Cabello, Noemi, Porras, Lourdes, Gijon, Paloma, Monereo, Alfonso, Abad, Daniel, Zuñiga, Sonia, Sola, Isabel, Rodon, Jordi, Vergara-Alert, Julia, Izquierdo-Useros, Nuria, Fudio, Salvador, Pontes, Maria Jose, de Rivas, Beatriz, de Velasco, Patricia Giron, Nieto, Antonio, Gomez, Javier, Aviles, Pablo, Lubomirov, Rubin, Belgrano, Alvaro, Sopesen, Belen, White, Kris M, Rosales, Romel, Yildiz, Soner, Reuschl, Ann-Kathrin, Thorne, Lucy G, Jolly, Clare, Towers, Greg J, Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, McGovern, Briana L, Rodriguez, M Luis, Enjuanes, Luis, Fernandez-Sousa, Jose M, Krogan, Nevan J, Jimeno, Jose M, Garcia-Sastre, Adolfo

المصدر: Life Science Alliance. 5(4)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Coronaviruses Therapeutics and Interventions, Patient Safety, Clinical Trials and Supportive Activities, Clinical Research, Infectious Diseases, Lung, Coronaviruses, Emerging Infectious Diseases, 6.1 Pharmaceuticals, Good Health and Well Being, Adult, Aged, COVID-19, Cell Line, Tumor, Depsipeptides, Drug Evaluation, Preclinical, Female, Hospitalization, Humans, Kaplan-Meier Estimate, Length of Stay, Male, Middle Aged, Neutropenia, Peptides, Cyclic, SARS-CoV-2, Treatment Outcome, Viral Load, COVID-19 Drug Treatment, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5pg2r03w
https://escholarship.org/content/qt5pg2r03w/qt5pg2r03w.pdf

المؤلفون: Tummino, Tia A, Rezelj, Veronica V, Fischer, Benoit, Fischer, Audrey, O'Meara, Matthew J, Monel, Blandine, Vallet, Thomas, White, Kris M, Zhang, Ziyang, Alon, Assaf, Schadt, Heiko, O'Donnell, Henry R, Lyu, Jiankun, Rosales, Romel, McGovern, Briana L, Rathnasinghe, Raveen, Jangra, Sonia, Schotsaert, Michael, Galarneau, Jean-René, Krogan, Nevan J, Urban, Laszlo, Shokat, Kevan M, Kruse, Andrew C, García-Sastre, Adolfo, Schwartz, Olivier, Moretti, Francesca, Vignuzzi, Marco, Pognan, Francois, Shoichet, Brian K

المصدر: Science. 373(6554)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Infectious Diseases, Orphan Drug, Rare Diseases, Clinical Research, Emerging Infectious Diseases, Clinical Trials and Supportive Activities, Coronaviruses, 5.1 Pharmaceuticals, Good Health and Well Being, A549 Cells, Animals, Antiviral Agents, COVID-19, Cations, Chlorocebus aethiops, Dose-Response Relationship, Drug, Drug Repositioning, Female, Humans, Lipidoses, Mice, Microbial Sensitivity Tests, Phospholipids, SARS-CoV-2, Surface-Active Agents, Vero Cells, Virus Replication, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/41h684bv
https://escholarship.org/content/qt41h684bv/qt41h684bv.pdf

المؤلفون: Le, Brian L, Andreoletti, Gaia, Oskotsky, Tomiko, Vallejo-Gracia, Albert, Rosales, Romel, Yu, Katharine, Kosti, Idit, Leon, Kristoffer E, Bunis, Daniel G, Li, Christine, Kumar, G Renuka, White, Kris M, García-Sastre, Adolfo, Ott, Melanie, Sirota, Marina

المصدر: Scientific reports. 11(1)

مصطلحات موضوعية: Humans, Antiviral Agents, Computational Biology, Drug Repositioning, Transcriptome, COVID-19, SARS-CoV-2, Vaccine Related, Infectious Diseases, Biodefense, Pneumonia, Emerging Infectious Diseases, Lung, Prevention, 5.1 Pharmaceuticals, Infection

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/44s17770

المؤلفون: White, Kris M, Rosales, Romel, Yildiz, Soner, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Jangra, Sonia, Uccellini, Melissa B, Rathnasinghe, Raveen, Coughlan, Lynda, Martinez-Romero, Carles, Batra, Jyoti, Rojc, Ajda, Bouhaddou, Mehdi, Fabius, Jacqueline M, Obernier, Kirsten, Dejosez, Marion, Guillén, María José, Losada, Alejandro, Avilés, Pablo, Schotsaert, Michael, Zwaka, Thomas, Vignuzzi, Marco, Shokat, Kevan M, Krogan, Nevan J, García-Sastre, Adolfo

المصدر: Science. 371(6532)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Emerging Infectious Diseases, Infectious Diseases, Biodefense, Biotechnology, Coronaviruses, Lung, Coronaviruses Therapeutics and Interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Adenosine Monophosphate, Alanine, Animals, Antiviral Agents, COVID-19, Coronavirus Nucleocapsid Proteins, Depsipeptides, Drug Evaluation, Preclinical, Female, HEK293 Cells, Humans, Mice, Inbred C57BL, Mutation, Peptide Elongation Factor 1, Peptides, Cyclic, Phosphoproteins, RNA, Viral, SARS-CoV-2, Virus Replication, COVID-19 Drug Treatment, Mice, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7nx3v3h2
https://escholarship.org/content/qt7nx3v3h2/qt7nx3v3h2.pdf

المؤلفون: Schoof, Michael, Faust, Bryan, Saunders, Reuben A, Sangwan, Smriti, Rezelj, Veronica, Hoppe, Nick, Boone, Morgane, Billesbølle, Christian B, Puchades, Cristina, Azumaya, Caleigh M, Kratochvil, Huong T, Zimanyi, Marcell, Deshpande, Ishan, Liang, Jiahao, Dickinson, Sasha, Nguyen, Henry C, Chio, Cynthia M, Merz, Gregory E, Thompson, Michael C, Diwanji, Devan, Schaefer, Kaitlin, Anand, Aditya A, Dobzinski, Niv, Zha, Beth Shoshana, Simoneau, Camille R, Leon, Kristoffer, White, Kris M, Chio, Un Seng, Gupta, Meghna, Jin, Mingliang, Li, Fei, Liu, Yanxin, Zhang, Kaihua, Bulkley, David, Sun, Ming, Smith, Amber M, Rizo, Alexandrea N, Moss, Frank, Brilot, Axel F, Pourmal, Sergei, Trenker, Raphael, Pospiech, Thomas, Gupta, Sayan, Barsi-Rhyne, Benjamin, Belyy, Vladislav, Barile-Hill, Andrew W, Nock, Silke, Liu, Yuwei, Krogan, Nevan J, Ralston, Corie Y, Swaney, Danielle L, García-Sastre, Adolfo, Ott, Melanie, Vignuzzi, Marco, Walter, Peter, Manglik, Aashish, Braxton, Julian R, Lopez, Kyle E, Melo, Arthur, Paulino, Joana, Pospiech, Thomas H, Thomas, Paul V, Wang, Feng, Yu, Zanlin, Dickinson, Miles Sasha, Asarnow, Daniel, Campbell, Melody G, Li, Junrui, Tsui, Tsz Kin Martin, Trinidad, Donovan, Tse, Eric, Zhou, Fengbo, Herrera, Nadia, Schulze-Gahmen, Ursula

المصدر: Science. 370(6523)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Infectious Diseases, Emerging Infectious Diseases, Coronaviruses, Biodefense, Infection, Angiotensin-Converting Enzyme 2, Animals, Antibodies, Neutralizing, Antibodies, Viral, Antibody Affinity, Chlorocebus aethiops, Cryoelectron Microscopy, Humans, Neutralization Tests, Protein Binding, Protein Stability, Single-Domain Antibodies, Spike Glycoprotein, Coronavirus, Vero Cells, QCRG Structural Biology Consortium, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1ks1d323
https://escholarship.org/content/qt1ks1d323/qt1ks1d323.pdf

المؤلفون: Miorin, Lisa, Kehrer, Thomas, Sanchez-Aparicio, Maria Teresa, Zhang, Ke, Cohen, Phillip, Patel, Roosheel S, Cupic, Anastasija, Makio, Tadashi, Mei, Menghan, Moreno, Elena, Danziger, Oded, White, Kris M, Rathnasinghe, Raveen, Uccellini, Melissa, Gao, Shengyan, Aydillo, Teresa, Mena, Ignacio, Yin, Xin, Martin-Sancho, Laura, Krogan, Nevan J, Chanda, Sumit K, Schotsaert, Michael, Wozniak, Richard W, Ren, Yi, Rosenberg, Brad R, Fontoura, Beatriz MA, García-Sastre, Adolfo

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 117(45)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Coronaviruses, Infectious Diseases, Emerging Infectious Diseases, 2.1 Biological and endogenous factors, Infection, Good Health and Well Being, Active Transport, Cell Nucleus, Animals, Binding Sites, COVID-19, Chlorocebus aethiops, HEK293 Cells, Humans, Interferons, Nuclear Matrix-Associated Proteins, Nuclear Pore, Nuclear Pore Complex Proteins, Nucleocytoplasmic Transport Proteins, Protein Binding, STAT1 Transcription Factor, STAT2 Transcription Factor, Signal Transduction, Vero Cells, Viral Proteins, Medical Microbiology, Biomedical and Clinical Sciences, Vaccine Related, Biodefense, Lung, Immunization, Coronaviruses Therapeutics and Interventions, Biotechnology, SARS-CoV-2, interferon signaling antagonism, STATs, ORF6, Nup98

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/00c2z9b4
https://escholarship.org/content/qt00c2z9b4/qt00c2z9b4.pdf

المؤلفون: Riva, Laura, Yuan, Shuofeng, Yin, Xin, Martin-Sancho, Laura, Matsunaga, Naoko, Pache, Lars, Burgstaller-Muehlbacher, Sebastian, De Jesus, Paul D, Teriete, Peter, Hull, Mitchell V, Chang, Max W, Chan, Jasper Fuk-Woo, Cao, Jianli, Poon, Vincent Kwok-Man, Herbert, Kristina M, Cheng, Kuoyuan, Nguyen, Tu-Trinh H, Rubanov, Andrey, Pu, Yuan, Nguyen, Courtney, Choi, Angela, Rathnasinghe, Raveen, Schotsaert, Michael, Miorin, Lisa, Dejosez, Marion, Zwaka, Thomas P, Sit, Ko-Yung, Martinez-Sobrido, Luis, Liu, Wen-Chun, White, Kris M, Chapman, Mackenzie E, Lendy, Emma K, Glynne, Richard J, Albrecht, Randy, Ruppin, Eytan, Mesecar, Andrew D, Johnson, Jeffrey R, Benner, Christopher, Sun, Ren, Schultz, Peter G, Su, Andrew I, García-Sastre, Adolfo, Chatterjee, Arnab K, Yuen, Kwok-Yung, Chanda, Sumit K

المصدر: Nature. 586(7827)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Infectious Diseases, Lung, Pneumonia & Influenza, Orphan Drug, Emerging Infectious Diseases, Coronaviruses Therapeutics and Interventions, Pneumonia, Coronaviruses, Rare Diseases, Stem Cell Research, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Adenosine Monophosphate, Alanine, Alveolar Epithelial Cells, Antiviral Agents, Betacoronavirus, COVID-19, Cell Line, Coronavirus Infections, Cysteine Proteinase Inhibitors, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Drug Repositioning, Drug Synergism, Gene Expression Regulation, Humans, Hydrazones, Induced Pluripotent Stem Cells, Models, Biological, Morpholines, Pandemics, Pneumonia, Viral, Pyrimidines, Reproducibility of Results, SARS-CoV-2, Small Molecule Libraries, Triazines, Virus Internalization, Virus Replication, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6p88f41f
https://escholarship.org/content/qt6p88f41f/qt6p88f41f.pdf

المؤلفون: Bouhaddou, Mehdi, Memon, Danish, Meyer, Bjoern, White, Kris M, Rezelj, Veronica V, Correa Marrero, Miguel, Polacco, Benjamin J, Melnyk, James E, Ulferts, Svenja, Kaake, Robyn M, Batra, Jyoti, Richards, Alicia L, Stevenson, Erica, Gordon, David E, Rojc, Ajda, Obernier, Kirsten, Fabius, Jacqueline M, Soucheray, Margaret, Miorin, Lisa, Moreno, Elena, Koh, Cassandra, Tran, Quang Dinh, Hardy, Alexandra, Robinot, Rémy, Vallet, Thomas, Nilsson-Payant, Benjamin E, Hernandez-Armenta, Claudia, Dunham, Alistair, Weigang, Sebastian, Knerr, Julian, Modak, Maya, Quintero, Diego, Zhou, Yuan, Dugourd, Aurelien, Valdeolivas, Alberto, Patil, Trupti, Li, Qiongyu, Hüttenhain, Ruth, Cakir, Merve, Muralidharan, Monita, Kim, Minkyu, Jang, Gwendolyn, Tutuncuoglu, Beril, Hiatt, Joseph, Guo, Jeffrey Z, Xu, Jiewei, Bouhaddou, Sophia, Mathy, Christopher JP, Gaulton, Anna, Manners, Emma J, Félix, Eloy, Shi, Ying, Goff, Marisa, Lim, Jean K, McBride, Timothy, O'Neal, Michael C, Cai, Yiming, Chang, Jason CJ, Broadhurst, David J, Klippsten, Saker, De Wit, Emmie, Leach, Andrew R, Kortemme, Tanja, Shoichet, Brian, Ott, Melanie, Saez-Rodriguez, Julio, tenOever, Benjamin R, Mullins, R Dyche, Fischer, Elizabeth R, Kochs, Georg, Grosse, Robert, García-Sastre, Adolfo, Vignuzzi, Marco, Johnson, Jeffery R, Shokat, Kevan M, Swaney, Danielle L, Beltrao, Pedro, Krogan, Nevan J

المصدر: Cell. 182(3)

مصطلحات موضوعية: Caco-2 Cells, Vero Cells, Animals, Humans, Pneumonia, Viral, Coronavirus Infections, Peptidyl-Dipeptidase A, Casein Kinase II, Cyclin-Dependent Kinases, p38 Mitogen-Activated Protein Kinases, Receptor Protein-Tyrosine Kinases, Proto-Oncogene Proteins, Protein Kinase Inhibitors, Antiviral Agents, Drug Evaluation, Preclinical, Proteomics, Phosphorylation, Host-Pathogen Interactions, Phosphatidylinositol 3-Kinases, HEK293 Cells, Pandemics, Spike Glycoprotein, Coronavirus, A549 Cells, Betacoronavirus, Phosphoinositide-3 Kinase Inhibitors, Chlorocebus aethiops, COVID-19, Angiotensin-Converting Enzyme 2, SARS-CoV-2, AXL, CDK, MAPK, PIKFYVE, antiviral, casein kinase II, mass spectrometry, p38, phosphoproteomics, Infectious Diseases, Prevention, Biodefense, Emerging Infectious Diseases, Vaccine Related, Lung, Infection, Developmental Biology, Biological Sciences, Medical and Health Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4431p9mq

المؤلفون: Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M, O’Meara, Matthew J, Rezelj, Veronica V, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher JP, Perica, Tina, Pilla, Kala Bharath, Ganesan, Sai J, Saltzberg, Daniel J, Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A, Bohn, Markus, Safari, Maliheh, Ugur, Fatima S, Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O’Neal, Michael C, Cai, Yiming, Chang, Jason CJ, Broadhurst, David J, Klippsten, Saker, Sharp, Phillip P, Wenzell, Nicole A, Kuzuoglu-Ozturk, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M, Cavero, Devin A, Hiatt, Joseph, Roth, Theodore L, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M, Frankel, Alan D, Rosenberg, Oren S, Verba, Kliment A, Agard, David A, Ott, Melanie, Emerman, Michael, Jura, Natalia

المصدر: Nature. 583(7816)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Biomedical and Clinical Sciences, Coronaviruses Therapeutics and Interventions, Emerging Infectious Diseases, Infectious Diseases, Coronaviruses, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Animals, Antiviral Agents, Betacoronavirus, COVID-19, Chlorocebus aethiops, Cloning, Molecular, Coronavirus Infections, Drug Evaluation, Preclinical, Drug Repositioning, HEK293 Cells, Host-Pathogen Interactions, Humans, Immunity, Innate, Mass Spectrometry, Molecular Targeted Therapy, Pandemics, Pneumonia, Viral, Protein Binding, Protein Biosynthesis, Protein Domains, Protein Interaction Mapping, Protein Interaction Maps, Receptors, sigma, SARS-CoV-2, SKP Cullin F-Box Protein Ligases, Vero Cells, Viral Proteins, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2gt3q50x
https://escholarship.org/content/qt2gt3q50x/qt2gt3q50x.pdf

المؤلفون: Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, O'Meara, Matthew J, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Shen, Wenqi, Shi, Ying, Zhang, Ziyang, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Mathy, Christopher JP, Perica, Tina, Pilla, Kala B, Ganesan, Sai J, Saltzberg, Daniel J, Ramachandran, Rakesh, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Lin, Yizhu, Wankowicz, Stephanie A, Bohn, Markus, Trenker, Raphael, Young, Janet M, Cavero, Devin, Hiatt, Joe, Roth, Theo, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Roesch, Ferdinand, Vallet, Thomas, Meyer, Björn, White, Kris M, Miorin, Lisa, Agard, David, Emerman, Michael, Ruggero, Davide, García-Sastre, Adolfo, Jura, Natalia, von Zastrow, Mark, Taunton, Jack, Schwartz, Olivier, Vignuzzi, Marco, d'Enfert, Christophe, Mukherjee, Shaeri, Jacobson, Matt, Malik, Harmit S, Fujimori, Danica G, Ideker, Trey, Craik, Charles S, Floor, Stephen, Fraser, James S, Gross, John, Sali, Andrej, Kortemme, Tanja, Beltrao, Pedro, Shokat, Kevan, Shoichet, Brian K, Krogan, Nevan J

مصطلحات موضوعية: Prevention, Vaccine Related, Biodefense, Infectious Diseases, Rare Diseases, Pneumonia & Influenza, Emerging Infectious Diseases, Lung, Pneumonia, 5.1 Pharmaceuticals, 2.2 Factors relating to the physical environment, Infection

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9v71w6zc

المؤلفون: Heinz, Sven, Texari, Lorane, Hayes, Michael GB, Urbanowski, Matthew, Chang, Max W, Givarkes, Ninvita, Rialdi, Alexander, White, Kris M, Albrecht, Randy A, Pache, Lars, Marazzi, Ivan, García-Sastre, Adolfo, Shaw, Megan L, Benner, Christopher

المصدر: Cell. 174(6)

مصطلحات موضوعية: Cell Line, Chromatin, Macrophages, Humans, Piperidines, Flavonoids, RNA Polymerase II, Carrier Proteins, Cell Cycle Proteins, Interferon-beta, Proto-Oncogene Proteins, Nuclear Proteins, Chromosomal Proteins, Non-Histone, Viral Nonstructural Proteins, RNA, Small Interfering, Transcription, Genetic, RNA Interference, Binding Sites, Protein Binding, Genome, Human, Influenza A Virus, H5N1 Subtype, CCCTC-Binding Factor, CTCF, NS1, chromatin compaction, cohesin, genome 3D structure, influenza A virus, readthrough transcription, transcription, transcription elongation, transcription termination, Emerging Infectious Diseases, Infectious Diseases, Influenza, Genetics, Pneumonia & Influenza, Human Genome, 1.1 Normal biological development and functioning, Underpinning research, Infection, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0mb94353

المؤلفون: Schimunek, Johannes, Seidl, Philipp, Elez, Katarina, Hempel, Tim, Le, Tuan, Noé, Frank, Olsson, Simon, Raich, Lluís, Winter, Robin, Gokcan, Hatice, Gusev, Filipp, Gutkin, Evgeny M, Isayev, Olexandr, Kurnikova, Maria G, Narangoda, Chamali H, Zubatyuk, Roman, Bosko, Ivan P, Furs, Konstantin V, Karpenko, Anna D, Kornoushenko, Yury V, Shuldau, Mikita, Yushkevich, Artsemi, Benabderrahmane, Mohammed, Bousquet-Melou, Patrick, Bureau, Ronan, Charton, Beatrice, Cirou, Bertrand, Gil, Gérard, Allen, William J, Sirimulla, Suman, Watowich, Stanley, Antonopoulos, Nick, Epitropakis, Nikolaos, Krasoulis, Agamemnon, Pitsikalis, Vassilis, Theodorakis, Stavros, Kozlovskii, Igor, Maliutin, Anton, Medvedev, Alexander, Popov, Petr, Zaretckii, Mark, Eghbal-Zadeh, Hamid, Halmich, Christina, Hochreiter, Sepp, Mayr, Andreas, Ruch, Peter, Widrich, Michael, Berenger, Francois, Kumar, Ashutosh, Yamanishi, Yoshihiro, Zhang, Kam, Bengio, Emmanuel, Bengio, Yoshua, Jain, Moksh, Korablyov, Maksym, Liu, Cheng-Hao, Gilles, Marcous, GLAAB, Enrico, Barnsley, Kelly, Iyengar, Suhasini M, Ondrechen, Mary Jo, Haupt, V Joachim, Kaiser, Florian, Schroeder, Michael, Pugliese, Luisa, Albani, Simone, Athanasiou, Christina, Beccari, Andrea, Carloni, Paolo, D'Arrigo, Giulia, Gianquinto, Eleonora, Goßen, Jonas, Hanke, Anton, Joseph, Benjamin P, Kokh, Daria B, Kovachka, Sandra, Manelfi, Candida, Mukherjee, Goutam, Muñiz-Chicharro, Abraham, Musiani, Francesco, Nunes-Alves, Ariane, Paiardi, Giulia, Rossetti, Giulia, Sadiq, S Kashif, Spyrakis, Francesca, Talarico, Carmine, Tsengenes, Alexandros, Wade, Rebecca, Copeland, Conner, Gaiser, Jeremiah, Olson, Daniel R, Roy, Amitava, Venkatraman, Vishwesh, Wheeler, Travis J, Arthanari, Haribabu, Blaschitz, Klara, Cespugli, Marco, Durmaz, Vedat, Fackeldey, Konstantin, Fischer, Patrick D, Gorgulla, Christoph, Gruber, Christian, Gruber, Karl, Hetmann, Michael, Kinney, Jamie E, Das, Krishna M Padmanabha, Pandita, Shreya, Singh, Amit, Steinkellner, Georg, Tesseyre, Guilhem, Wagner, Gerhard, Wang, Zi-Fu, Yust, Ryan J, Druzhilovskiy, Dmitry S, Filimonov, Dmitry, Pogodin, Pavel V, Poroikov, Vladimir, Rudik, Anastassia V, Stolbov, Leonid A, Veselovsky, Alexander V, De Rosa, Maria, Simone, Giada De, Gulotta, Maria R, Lombino, Jessica, Mekni, Nedra, Perricone, Ugo, Casini, Arturo, Embree, Amanda, Gordon, D Benjamin, Lei, David, Pratt, Katelin, Voigt, Christopher A, Chen, Kuang-Yu, Jacob, Yves, Krischuns, Tim, Lafaye, Pierre, Zettor, Agnès, Rodríguez, M Luis, White, Kris M, Fearon, Daren, von Delft, Frank, Walsh, Martin A, Horvath, Dragos, Brooks, Charles L, Falsafi, Babak, Ford, Bryan, García-Sastre, Adolfo, Lee, Sang Yup, Naffakh, Nadia, Varnek, Alexandre, Klambauer, Guenter, Hermans, Thomas M

المساهمون: Luxembourg Centre for Systems Biomedicine (LCSB): Biomedical Data Science (Glaab Group)

المصدر: Molecular Informatics (2023-10-13)

مصطلحات موضوعية: SARS-Cov2, computational drug discovery, covid-19, Organic Chemistry, Computer Science Applications, Drug Discovery, Molecular Medicine, Structural Biology, Human health sciences, Immunology & infectious disease, Life sciences, Physical, chemical, mathematical & earth Sciences, Sciences de la santé humaine, Immunologie & maladie infectieuse, Sciences du vivant, Physique, chimie, mathématiques & sciences de la terre

Relation: FNR14715687 - Combined In Silico Molecular Docking And In Vitro Experimental Assessment Of Drug Repurposing Candidates For Covid-19, 2020 (01/06/2020-30/11/2020) - Enrico Glaab; urn:issn:1868-1743; urn:issn:1868-1751; https://orbilu.uni.lu/handle/10993/57160; info:hdl:10993/57160; info:pmid:37833243

الاتاحة: https://orbilu.uni.lu/handle/10993/57160
https://orbilu.uni.lu/bitstream/10993/57160/1/a-community-effort-to-discover-small-molecule-sars-co-v-2-inhibitors.pdf
https://doi.org/10.1002/minf.202300262

المؤلفون: Wei, Jin, Patil, Ajinkya, Collings, Clayton K., Alfajaro, Mia Madel, Liang, Yu, Cai, Wesley L., Strine, Madison S., Filler, Renata B., DeWeirdt, Peter C., Hanna, Ruth E., Menasche, Bridget L., Ökten, Arya, Peña-Hernández, Mario A., Klein, Jon, McNamara, Andrew, Rosales, Romel, McGovern, Briana L., Luis Rodriguez, M., García-Sastre, Adolfo, White, Kris M., Qin, Yiren, Doench, John G., Yan, Qin, Iwasaki, Akiko, Zwaka, Thomas P., Qi, Jun, Kadoch, Cigall, Wilen, Craig B.

المساهمون: Burroughs Wellcome Fund, G. Harold and Leila Y. Mathers Foundation, Richard and Susan Smith Family Foundation, Ludwig Family Foundation and Emergent Ventures Fast Grant, National Science Foundation, U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute, U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases, United States Department of Defense | Defense Advanced Research Projects Agency, U.S. Department of Defense, Huffington Foundation, U.S. Department of Health & Human Services | NIH | NIH Office of the Director

المصدر: Nature Genetics ; volume 55, issue 3, page 471-483 ; ISSN 1061-4036 1546-1718

الاتاحة: http://dx.doi.org/10.1038/s41588-023-01307-z
https://www.nature.com/articles/s41588-023-01307-z.pdf
https://www.nature.com/articles/s41588-023-01307-z

المؤلفون: Kottur, Jithesh, White, Kris M., Rodriguez, M. Luis, Rechkoblit, Olga, Quintana-Feliciano, Richard, Nayar, Ahana, García-Sastre, Adolfo, Aggarwal, Aneel K.

المساهمون: Rey, Félix A., National Institute of General Medical Sciences, Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, DOE Office of Biological and Environmental Research, DOE Office of Science

المصدر: PLOS Pathogens ; volume 19, issue 7, page e1011546 ; ISSN 1553-7374

الاتاحة: http://dx.doi.org/10.1371/journal.ppat.1011546
https://dx.plos.org/10.1371/journal.ppat.1011546

المؤلفون: Déjosez, Marion, Marin, Arturo, Hughes, Graham M., Morales, Ariadna E., Godoy-Parejo, Carlos, Gray, Jonathan L., Qin, Yiren, Singh, Arun A., Xu, Hui, Juste, Javier, Ibáñez, Carlos, White, Kris M., Rosales, Romel, Francoeur, Nancy J., Sebra, Robert P., Alcock, Dominic, Volkert, Thomas L., Puechmaille, Sébastien J., Pastusiak, Andrzej, Frost, Simon D.W., Hiller, Michael, Young, Richard A., Teeling, Emma C., García-Sastre, Adolfo, Zwaka, Thomas P.

المصدر: Cell ; volume 186, issue 5, page 957-974.e28 ; ISSN 0092-8674

الاتاحة: http://dx.doi.org/10.1016/j.cell.2023.01.011
https://api.elsevier.com/content/article/PII:S0092867423000417?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0092867423000417?httpAccept=text/plain

المؤلفون: Pohl, Marie O, Martin-Sancho, Laura, Ratnayake, Ranjala, White, Kris M, Riva, Laura, Chen, Qi-Yin, Lieber, Gauthier, Busnadiego, Idoia, Yin, Xin, Lin, Samuel, Pu, Yuan, Pache, Lars, Rosales, Romel, Déjosez, Marion, Qin, Yiren, De Jesus, Paul D, Beall, Anne, Yoh, Sunnie, Hale, Benjamin G, Zwaka, Thomas P, Matsunaga, Naoko, García-Sastre, Adolfo, Stertz, Silke, Chanda, Sumit K, Luesch, Hendrik

المصدر: Pohl, Marie O; Martin-Sancho, Laura; Ratnayake, Ranjala; White, Kris M; Riva, Laura; Chen, Qi-Yin; Lieber, Gauthier; Busnadiego, Idoia; Yin, Xin; Lin, Samuel; Pu, Yuan; Pache, Lars; Rosales, Romel; Déjosez, Marion; Qin, Yiren; De Jesus, Paul D; Beall, Anne; Yoh, Sunnie; Hale, Benjamin G; Zwaka, Thomas P; Matsunaga, Naoko; García-Sastre, Adolfo; Stertz, Silke; Chanda, Sumit K; Luesch, Hendrik (2022). Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity. ACS Infectious Diseases, 8(7):1265-1279.

مصطلحات موضوعية: Institute of Medical Virology, 570 Life sciences, biology, 610 Medicine & health

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/227078/1/ZORA_227078.pdf; info:pmid/35766385; urn:issn:2373-8227

الاتاحة: https://www.zora.uzh.ch/id/eprint/227078/
https://www.zora.uzh.ch/id/eprint/227078/1/ZORA_227078.pdf
https://doi.org/10.1021/acsinfecdis.2c00008

المؤلفون: Simba Lahuasi, Alvaro, Cantero Camacho, Ángel, Rosales, Romel, McGovern, Briana Lynn, Rodríguez, M. Luis, Marchán Sancho, Vicente, White, Kris M., García Sastre, Adolfo, Gallego, José

المصدر: Articles publicats en revistes (Química Inorgànica i Orgànica)

مصطلحات موضوعية: COVID-19, RNA

وصف الملف: 17 p.; application/pdf

Relation: Reproducció del document publicat a: https://doi.org/10.3390/ph15121448; Pharmaceuticals, 2022, vol. 15, p. 1448; https://doi.org/10.3390/ph15121448; http://hdl.handle.net/2445/193697; 729642

الاتاحة: http://hdl.handle.net/2445/193697

المؤلفون: Varona, Jose F., Landete, Pedro, Lopez-Martin, Jose A., Estrada, Vicente, Paredes, Roger, Guisado-Vasco, Pablo, Fernandez de Orueta, Lucia, Torralba, Miguel, Fortún, Jesús, Vates, Roberto, Barberán, José, Clotet Sala, Bonaventura, Ancochea, Julio, Carnevali, Daniel, Cabello, Noemi, Porras, Lourdes, Gijon, Paloma, Monereo, Alfonso, Abad, Daniel, Zuñiga, Sonia, Sola, Isabel, Rodon, Jordi, Vergara-Alert, Júlia, Izquierdo Useros, Nuria, Fudio, Salvador, Pontes, Maria Jose, de Rivas, Beatriz, Giron de Velasco, Patricia, Nieto, Antonio, Gomez, Javier, Avilés, Pablo, Lubomirov, Rubin, Belgrano, Alvaro, Sopesen, Belen, White, Kris M., Rosales, Romel, Yildiz, Soner, Reuschl, Ann-Kathrin, Thorne, Lucy G., Jolly, Clare, Towers, Greg J., Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, McGovern, Briana L., Rodriguez, M. Luis, Enjuanes, Luis, Fernandez-Sousa, Jose M., Krogan, Nevan J., Jimeno, Jose M., Garcia-Sastre, Adolfo

وصف الملف: application/pdf

Relation: Life Science Alliance; Vol. 5 (january 2022); https://ddd.uab.cat/record/252184; urn:10.26508/lsa.202101200; urn:oai:ddd.uab.cat:252184; urn:pmcid:PMC8761492; urn:pmid:35012962; urn:oai:pubmedcentral.nih.gov:8761492

الاتاحة: https://ddd.uab.cat/record/252184

المؤلفون: Siddiq, Mustafa M., Chan, Angel T., Miorin, Lisa, Yadaw, Arjun S., Beaumont, Kristin G., Kehrer, Thomas, Cupic, Anastasija, White, Kris M., Tolentino, Rosa E., Hu, Bin, Stern, Alan D., Tavassoly, Iman, Hansen, Jens, Sebra, Robert, Martinez, Pedro, Prabha, Som, Dubois, Nicole, Schaniel, Christoph, Iyengar-Kapuganti, Rupa, Kukar, Nina, Giustino, Gennaro, Sud, Karan, Nirenberg, Sharon, Kovatch, Patricia, Albrecht, Randy A., Goldfarb, Joseph, Croft, Lori, McLaughlin, Maryann A., Argulian, Edgar, Lerakis, Stamatios, Narula, Jagat, García-Sastre, Adolfo, Iyengar, Ravi

المساهمون: Gallagher, Tom, CRIP Center for Research on Influenza Pathogenesis, CRIPT Center for Research on Influenza Pathogenesis and Transmission, American Heart Association, HHS | NIH | National Cancer Institute, HHS | NIH | National Institute of Allergy and Infectious Diseases, HHS | National Institutes of Health, JPB Foundation

المصدر: Journal of Virology ; volume 96, issue 2 ; ISSN 0022-538X 1098-5514

الاتاحة: http://dx.doi.org/10.1128/jvi.01063-21
https://journals.asm.org/doi/pdf/10.1128/JVI.01063-21