المؤلفون: Hemin Chin, Werner A. Klee, Dong Sun Kim

المصدر: FEBS Letters. 376:11-14

مصطلحات موضوعية: Binding activity, Narcotics, Agonist, medicine.medical_specialty, medicine.drug_class, Narcotic Antagonists, Biophysics, Diprenorphine, Down-Regulation, Hybrid Cells, Biology, Biochemistry, Cell Line, δ-opioid receptor, Mice, Neuroblastoma, Estrogen-related receptor alpha, Opiate, Structural Biology, Nalorphine, Receptors, Opioid, delta, Dopamine receptor D2, Internal medicine, Genetics, medicine, Animals, 5-HT5A receptor, RNA, Messenger, Molecular Biology, Protease-activated receptor 2, Insulin-like growth factor 1 receptor, δ-Opioid receptor, Sigma-1 receptor, Morphine, Etorphine, Membrane Proteins, Cell Biology, Blotting, Northern, Rats, Endocrinology, Transcription

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2436c7f3f546ad34066a0aa2ddfc5496
https://doi.org/10.1016/0014-5793(95)01233-6

المؤلفون: Dianne L. Newton, Werner A. Klee

المصدر: FEBS Letters. 271:207-210

مصطلحات موضوعية: GTP', G protein, Biophysics, Adenylate kinase, Biochemistry, Cyclase, Reconstitution, GTP-Binding Proteins, Structural Biology, parasitic diseases, Genetics, Animals, Adenylate cyclase, heterocyclic compounds, Nucleotide, Molecular Biology, chemistry.chemical_classification, Fatty Acids, Brain, social sciences, Cell Biology, Rats, Cholesterol, Enzyme, chemistry, G12/G13 alpha subunits, Liposomes, Phosphatidylcholines, population characteristics, Guanosine Triphosphate, human activities, Cyclase activity, Adenylyl Cyclases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f3601ac6af1ed46b96b26d6029456a
https://doi.org/10.1016/0014-5793(90)80407-a

المؤلفون: Christine Zioudrou, Richard A. Streaty, Werner A. Klee

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://fondation-maladies-degeneratives.org/Articles/a0f14213437ad7df55b7176fcea35bdf.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.457.3712; http://fondation-maladies-degeneratives.org/Articles/a0f14213437ad7df55b7176fcea35bdf.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.457.3712
http://fondation-maladies-degeneratives.org/Articles/a0f14213437ad7df55b7176fcea35bdf.pdf

المؤلفون: Christine A. Kozak, Tomasz Bzdega, Hyun Uk Kim, Werner A. Klee, Hemin Chin, Hyun Ho Jung

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 90(20)

مصطلحات موضوعية: clone (Java method), DNA, Complementary, Genetic Linkage, Molecular Sequence Data, Gene Expression, In situ hybridization, Biology, Mice, Anterior pituitary, Receptors, Opioid, delta, Gene expression, medicine, Animals, Amino Acid Sequence, RNA, Messenger, Cloning, Molecular, Receptor, Opioid peptide, Gene, In Situ Hybridization, Multidisciplinary, Base Sequence, Brain, Molecular biology, Rats, Chromosome 4, medicine.anatomical_structure, Genes, Oligonucleotide Probes, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc3f4b0d2db89cee1e938393ad2015f
https://pubmed.ncbi.nlm.nih.gov/8415697

المؤلفون: Werner A. Klee, Marshall W. Nirenberg

المصدر: Proceedings of the National Academy of Sciences. 71:3474-3477

مصطلحات موضوعية: Receptors, Drug, Cell, Nerve Tissue Proteins, (+)-Naloxone, Hybrid Cells, Pharmacology, Biology, Tritium, Cell Line, Mice, Neuroblastoma, Glioma, medicine, Animals, Neoplasm, Receptor, neoplasms, Morphine Derivatives, Multidisciplinary, Morphine, Naloxone, medicine.disease, Rats, medicine.anatomical_structure, Cell culture, Cancer research, Biological Sciences: Biochemistry, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3fb0a3d5c4713a11d858e7aa7d9f5b6
https://doi.org/10.1073/pnas.71.9.3474

المؤلفون: Graeme Milligan, Allen M. Spiegel, Peter Gierschik, Werner A. Klee, R A Streaty

المصدر: Journal of Biological Chemistry. 262:8626-8630

مصطلحات موضوعية: medicine.medical_specialty, GTP', Adenylate kinase, Cell Biology, Neurotransmission, Biology, Biochemistry, Cyclase, δ-opioid receptor, GTP-binding protein regulators, Endocrinology, Internal medicine, medicine, μ-opioid receptor, Receptor, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fa868525f924e7fb4c32e6d25f1d66c3
https://doi.org/10.1016/s0021-9258(18)47459-5

المؤلفون: Arthur E. Jacobson, William F. Simonds, Kenner C. Rice, Terrence R. Burke, Werner A. Klee

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 21:693-702

مصطلحات موضوعية: Tritium illumination, Chemistry, Narcotic, medicine.drug_class, Ligand, Stereochemistry, medicine.medical_treatment, Organic Chemistry, Receptor-mediated endocytosis, Biochemistry, Analytical Chemistry, Opioid, Opioid receptor, Drug Discovery, medicine, Radiology, Nuclear Medicine and imaging, Amine gas treating, Tritium, Spectroscopy, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ce5b46bdabfdccb0e7a4eaadd9a42488
https://doi.org/10.1002/jlcr.2580210802

المؤلفون: Greg Koski, Richard A. Streaty, William F. Simonds, Werner A. Klee, Leonard M. Hjelmeland

المصدر: Proceedings of the National Academy of Sciences. 77:4623-4627

مصطلحات موضوعية: Detergents, Cell Line, chemistry.chemical_compound, medicine, Animals, Trypsin, Receptor, Opioid peptide, Stokes radius, Brain Chemistry, Neurons, Multidisciplinary, Chemistry, Cholic acid, Rats, Membrane, Solubility, Biochemistry, Ethylmaleimide, Cell culture, Receptors, Opioid, Cattle, Derivative (chemistry), Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851d9a896e22ee1f2abe3aa4b3859fcf
https://doi.org/10.1073/pnas.77.8.4623

المؤلفون: Marina Mata, Harold Gainer, Werner A. Klee

المصدر: Life Sciences. 21:1159-1162

مصطلحات موضوعية: Male, Vasopressin, medicine.medical_specialty, Endogeny, General Biochemistry, Genetics and Molecular Biology, Pituitary Gland, Posterior, Internal medicine, medicine, Animals, Dehydration, General Pharmacology, Toxicology and Pharmaceutics, Chemistry, Adrenalectomy, Enkephalins, General Medicine, medicine.disease, Lobe, Rats, medicine.anatomical_structure, Endocrinology, Oxytocin, Diabetes insipidus, Endorphins, Opiate, Diabetes Insipidus, hormones, hormone substitutes, and hormone antagonists, Antidiuretic, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e69e74f17e4cbf8c7164e3e81756fd
https://doi.org/10.1016/0024-3205(77)90115-1

المؤلفون: Werner A. Klee, Marshall W. Nirenberg, Shail K. Sharma

المصدر: Proceedings of the National Academy of Sciences. 74:3365-3369

مصطلحات موضوعية: medicine.medical_specialty, Adenosine, Growth-hormone-releasing hormone receptor, Adenylate kinase, Hybrid Cells, Cyclase, Cell Line, Fluorides, Neuroblastoma, Enzyme activator, Histamine H2 receptor, Internal medicine, medicine, heterocyclic compounds, Cycloheximide, Guanylyl Imidodiphosphate, Multidisciplinary, Morphine, Naloxone, Chemistry, Prostaglandins E, Etorphine, Glioma, Guanylate cyclase 2C, Enzyme Activation, Kinetics, Endocrinology, Morphinans, Biochemistry, Cyclase activity, Adenylyl Cyclases, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8911acc1ccd226ad4e62bfe821724cc
https://doi.org/10.1073/pnas.74.8.3365

المؤلفون: Shail K. Sharma, Werner A. Klee, Marshall W. Nirenberg

المصدر: Proceedings of the National Academy of Sciences. 72:3092-3096

مصطلحات موضوعية: medicine.medical_specialty, Adenosine, Substance-Related Disorders, Adenylate kinase, (+)-Naloxone, Hybrid Cells, Pharmacology, Inhibitory postsynaptic potential, Models, Biological, Cyclase, Drug tolerance, Internal medicine, medicine, Humans, Receptor, Multidisciplinary, Morphine, biology, Naloxone, Chemistry, Prostaglandins E, Drug Tolerance, Enzyme assay, Endocrinology, biology.protein, Cell Division, Research Article, Adenylyl Cyclases, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcbbadbe687ec258634fd080feb297ee
https://doi.org/10.1073/pnas.72.8.3092

المؤلفون: Kenner C. Rice, Balbir S. Bajwa, Arthur E. Jacobson, Terrence R. Burke, Richard A. Streaty, Werner A. Klee

المصدر: Journal of Medicinal Chemistry. 27:1570-1574

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Chemical Phenomena, Stereochemistry, Narcotic Antagonists, Drug Evaluation, Preclinical, Receptors, Opioid, mu, Hybrid Cells, Ligands, Mass Spectrometry, Cell Line, δ-opioid receptor, Mice, Neuroblastoma, Structure-Activity Relationship, Thebaine, chemistry.chemical_compound, Receptors, Opioid, delta, Drug Discovery, medicine, Animals, Bicyclic molecule, Chemistry, Alkaloid, Cell Membrane, Biological activity, Glioma, Receptor-mediated endocytosis, In vitro, Rats, Fentanyl, Biochemistry, Receptors, Opioid, Isothiocyanate, Molecular Medicine, Benzimidazoles, Indicators and Reagents, Etonitazene, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4062f5bdd7a6fc31972f0f7e252dc90
https://doi.org/10.1021/jm00378a008

المؤلفون: Marshall W. Nirenberg, Werner A. Klee

المصدر: Nature. 263:609-612

مصطلحات موضوعية: beta-Lipotropin, Adenylate kinase, Nerve Tissue Proteins, Endogeny, Peptide, Hybrid Cells, Ligands, Cyclase, Cell Line, Guinea pig, Neuroblastoma, Melanocyte-Stimulating Hormones, Mode of action, chemistry.chemical_classification, Multidisciplinary, Morphine, Naloxone, Chemistry, Prostaglandins E, Glioma, Enzyme Activation, Kinetics, Biochemistry, Adenylyl Cyclase Inhibitors, Receptors, Opioid, Opiate, Oligopeptides, Cyclase activity, Adenylyl Cyclases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae1cb71231c25bd8944125eb2394d28
https://doi.org/10.1038/263609a0

المؤلفون: Werner A. Klee, R A Streaty, Christine Zioudrou

المصدر: Journal of Biological Chemistry. 254:2446-2449

مصطلحات موضوعية: chemistry.chemical_classification, biology, Dihydromorphine, Adenylate kinase, Cell Biology, Biochemistry, Gluten, Cyclase, Gluten exorphin, Pepsin, chemistry, Opioid, biology.protein, medicine, Opioid peptide, Molecular Biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::954eb1a44c582932aac21a3ad3fac7bc
https://doi.org/10.1016/s0021-9258(17)30243-0

المؤلفون: R A Streaty, Werner A. Klee, G Koski

المصدر: Journal of Biological Chemistry. 257:14035-14040

مصطلحات موضوعية: GTP', Chemistry, Adenylate kinase, Stimulation, Cell Biology, GTPase, Biochemistry, Cyclase, heterocyclic compounds, Receptor, Opioid peptide, Molecular Biology, Cyclase activity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e724f14c71ea0c98e81d33080a2a5de3
https://doi.org/10.1016/s0021-9258(19)45339-8

المؤلفون: Ikuo Iijima, Yasuko F. Jacquet, Junichi Minamikawa, Werner A. Klee, Kenner C. Rice

المصدر: Science. 198:842-845

مصطلحات موضوعية: medicine.medical_specialty, Guinea Pigs, Molecular Conformation, (+)-Naloxone, In Vitro Techniques, Binding, Competitive, Periaqueductal gray, Cyclase, Neuroblastoma, Structure-Activity Relationship, Internal medicine, medicine, Animals, Receptor, Microinjection, Morphine Derivatives, Binding Sites, Multidisciplinary, Behavior, Animal, Morphine, Naloxone, Chemistry, Ligand binding assay, Brain, Muscle, Smooth, Stereoisomerism, Glioma, Rats, Endocrinology, Adenylyl Cyclase Inhibitors, Receptors, Opioid, Opiate, Muscle Contraction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57c417c92ee9536df9be80706ce0aef
https://doi.org/10.1126/science.199942

المؤلفون: Werner A. Klee, Ralph A. Lessor, and Arthur E. Jacobson, Richard A. Streaty, Kenner C. Rice

المصدر: Neuropeptides. 5:229-232

مصطلحات موضوعية: Agonist, Alkylating Agents, medicine.drug_class, Stereochemistry, Receptors, Opioid, mu, In Vitro Techniques, Binding, Competitive, δ-opioid receptor, Thebaine, Cellular and Molecular Neuroscience, Endocrinology, Isothiocyanates, Receptors, Opioid, delta, medicine, Animals, Moiety, Receptor, Morphine Derivatives, Membranes, Endocrine and Autonomic Systems, Chemistry, Brain, General Medicine, Receptor-mediated endocytosis, Rats, Fentanyl, medicine.anatomical_structure, Neurology, Opioid, Receptors, Opioid, Biophysics, Benzimidazoles, μ-opioid receptor, Nucleus, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78c15096dfe322a201530a81d978fca
https://doi.org/10.1016/0143-4179(84)90069-6

المؤلفون: William F. Simonds, Arthur E. Jacobson, Terrence R. Burke, Kenner C. Rice, James V. Silverton, Richard A. Streaty, Werner A. Klee

المصدر: Journal of Medicinal Chemistry. 29:1087-1093

مصطلحات موضوعية: Enkephalin, medicine.drug_class, Stereochemistry, Acylation, Enkephalin, Methionine, Molecular Conformation, Receptors, Opioid, mu, In Vitro Techniques, Ligands, Tritium, δ-opioid receptor, Mice, X-Ray Diffraction, Isothiocyanates, Opioid receptor, Receptors, Opioid, delta, Drug Discovery, medicine, Animals, Enantiomeric excess, Analgesics, Chemistry, Absolute configuration, Brain, Stereoisomerism, Rats, 3-Methylfentanyl, Fentanyl, Adenylyl Cyclase Inhibitors, Receptors, Opioid, Molecular Medicine, Enantiomer, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7337e807741414779ec937d2d78f5208
https://doi.org/10.1021/jm00156a030

المؤلفون: Greg Koski, Werner A. Klee

المصدر: Proceedings of the National Academy of Sciences. 78:4185-4189

مصطلحات موضوعية: GTP', Adenylate kinase, GTPase, Cyclase, Adenylyl Cyclase Inhibitors, Cell Line, GTP Phosphohydrolases, Structure-Activity Relationship, Animals, heterocyclic compounds, Opioid peptide, Multidisciplinary, Chemistry, Cell Membrane, Stereoisomerism, Enkephalins, Enkephalin, Leucine-2-Alanine, Phosphoric Monoester Hydrolases, Rats, Biochemistry, Receptors, Opioid, Guanosine Triphosphate, Cyclase activity, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d2488253890063448b2ed7a39ccbca
https://doi.org/10.1073/pnas.78.7.4185

المؤلفون: Christine Zioudrou, R A Streaty, D. Varoucha, S. Loukas, Werner A. Klee, N Nicolaou

المصدر: Journal of Biological Chemistry. 258:10934-10937

مصطلحات موضوعية: Enkephalin, Stereochemistry, Chemistry, Antagonist, Cell Biology, (+)-Naloxone, Biochemistry, Membrane, Opioid, medicine, Opiate, Receptor, Molecular Biology, Cyclase activity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1227c3650f47253c5fa8ca08baf29d8a
https://doi.org/10.1016/s0021-9258(17)44365-1