نتائج البحث - "Welihinda, Ajith"

1

Academic Journal

Positive Allosteric Modulation of A2AR Alters Immune Cell Responses and Ameliorates Psoriasis-Like Dermatitis in Mice

المؤلفون: Welihinda, Ajith, Ravikumar, Puja, Kaur, Manmeet, Mechanic, Jordan, Yadav, Shruti, Kang, Gyeong Jin, Amento, Edward

المساهمون: National Psoriasis Foundation

المصدر: Journal of Investigative Dermatology ; volume 142, issue 3, page 624-632.e6 ; ISSN 0022-202X

الاتاحة: http://dx.doi.org/10.1016/j.jid.2021.07.174
https://api.elsevier.com/content/article/PII:S0022202X21021643?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0022202X21021643?httpAccept=text/plain

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2

Academic Journal

Gene Induction in Response to Unfolded Protein in the Endoplasmic Reticulum is Mediated through Ire1p Kinase Interaction with a Transcriptional Coactivator Complex Containing Ada5p

المؤلفون: Welihinda, Ajith A., Tirasophon, Witoon, Green, Sarah R., Kaufman, Randal J.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1997 Apr . 94(9), 4289-4294.

URL الوصول: https://www.jstor.org/stable/42003

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3

Academic Journal

Metabolism and disposition of the SGLT2 inhibitor bexagliflozin in rats, monkeys and humans

المؤلفون: Zhang, Wenbin, Li, Xiaoyan, Ding, Haifeng, Lu, Yuan, Stilwell, Geoff E., Halvorsen, Yuan-Di, Welihinda, Ajith

المصدر: Xenobiotica ; volume 50, issue 5, page 559-569 ; ISSN 0049-8254 1366-5928

الاتاحة: http://dx.doi.org/10.1080/00498254.2019.1654634
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2019.1654634

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4

Academic Journal

Comparison of the Human A 2A Adenosine Receptor Recognition by Adenosine and Inosine: New Insight from Supervised Molecular Dynamics Simulations

المؤلفون: Deganutti, Giuseppe, Welihinda, Ajith, Moro, Stefano

مصطلحات موضوعية: Organic Chemistry, General Pharmacology, Toxicology and Pharmaceutics, Molecular Medicine, Drug Discovery, Biochemistry, Pharmacology

Relation: url:https://www.openaccessrepository.it/communities/itmirror; https://www.openaccessrepository.it/record/199018

الاتاحة: https://www.openaccessrepository.it/record/199018
https://doi.org/10.1002/cmdc.201700200

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5

Academic Journal

Positive allosteric modulation of the adenosine A2a receptor attenuates inflammation

المؤلفون: Welihinda, Ajith A, Amento, Edward P

المصدر: Journal of Inflammation ; volume 11, issue 1 ; ISSN 1476-9255

الاتاحة: http://dx.doi.org/10.1186/s12950-014-0037-0
http://link.springer.com/content/pdf/10.1186/s12950-014-0037-0.pdf
http://link.springer.com/article/10.1186/s12950-014-0037-0/fulltext.html
http://link.springer.com/content/pdf/10.1186/s12950-014-0037-0

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6

Patent

DNA encoding the novel mammalian protein, Ire1p

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7

Patent

Ire1p, novel mammalian protein, and gene encoding same

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8

Academic Journal

Interaction of Two Actin-binding Proteins, Synaptopodin and α-Actinin-4, with the Tight Junction Protein MAGI-1

المؤلفون: Patrie, Kevin M., Drescher, Andrew J., Welihinda, Ajith, Mundel, Peter, Margolis, Ben

المصدر: Journal of Biological Chemistry ; volume 277, issue 33, page 30183-30190 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.m203072200
https://api.elsevier.com/content/article/PII:S0021925818756895?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925818756895?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.M203072200

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9

Academic Journal

The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response

المؤلفون: Tirasophon, Witoon, Lee, Kyungho, Callaghan, Brian, Welihinda, Ajith, Kaufman, Randal J.

مصطلحات موضوعية: Research Papers

وصف الملف: text/html

Relation: http://genesdev.cshlp.org/cgi/content/short/14/21/2725; http://dx.doi.org/10.1101/gad.839400

الاتاحة: http://genesdev.cshlp.org/cgi/content/short/14/21/2725
https://doi.org/10.1101/gad.839400

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10

Academic Journal

The Transcriptional Co-activator ADA5 Is Required for HAC1 mRNA Processing in Vivo

المؤلفون: Welihinda, Ajith A., Tirasophon, Witoon, Kaufman, Randal J.

المصدر: Journal of Biological Chemistry ; volume 275, issue 5, page 3377-3381 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.275.5.3377
https://api.elsevier.com/content/article/PII:S0021925818309189?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925818309189?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.275.5.3377

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11

Academic Journal

Conservation and Divergence of the Yeast and Mammalian Unfolded Protein Response

المؤلفون: Foti, Dolly M., Welihinda, Ajith, Kaufman, Randal J., Lee, Amy S.

المصدر: Journal of Biological Chemistry ; volume 274, issue 43, page 30402-30409 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.274.43.30402
https://api.elsevier.com/content/article/PII:S0021925819516970?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925819516970?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.274.43.30402

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12

Academic Journal

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

المؤلفون: Tirasophon, Witoon, Welihinda, Ajith A., Kaufman, Randal J.

مصطلحات موضوعية: Research Papers

وصف الملف: text/html

Relation: http://www.genesdev.org/cgi/content/short/12/12/1812; http://dx.doi.org/10.1101/gad.12.12.1812

الاتاحة: http://www.genesdev.org/cgi/content/short/12/12/1812
https://doi.org/10.1101/gad.12.12.1812

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13

Academic Journal

Protein Serine/Threonine Phosphatase Ptc2p Negatively Regulates the Unfolded-Protein Response by Dephosphorylating Ire1p Kinase

المؤلفون: Welihinda, Ajith A., Tirasophon, Witoon, Green, Sarah R., Kaufman, Randal J.

المصدر: Molecular and Cellular Biology ; volume 18, issue 4, page 1967-1977 ; ISSN 1098-5549

الاتاحة: http://dx.doi.org/10.1128/mcb.18.4.1967
https://journals.asm.org/doi/pdf/10.1128/MCB.18.4.1967
https://www.tandfonline.com/doi/pdf/10.1128/MCB.18.4.1967

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14

Academic Journal

The Unfolded Protein Response Pathway in

المؤلفون: Welihinda, Ajith A., Kaufman, Randal J.

المصدر: Journal of Biological Chemistry ; volume 271, issue 30, page 18181-18187 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.271.30.18181
https://api.elsevier.com/content/article/PII:S0021925819870394?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925819870394?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.271.30.18181

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15

Academic Journal

Enhancement of inosine-mediated A 2A R signaling through positive allosteric modulation

المؤلفون: Welihinda, Ajith A., Kaur, Manmeet, Raveendran, Kaviya S., Amento, Edward P.

المساهمون: National Institute of Allergy and Infectious Diseases

المصدر: Cellular Signalling ; volume 42, page 227-235 ; ISSN 0898-6568

الاتاحة: http://dx.doi.org/10.1016/j.cellsig.2017.11.002
https://api.elsevier.com/content/article/PII:S0898656817302899?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0898656817302899?httpAccept=text/plain

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16

Academic Journal

Metabolism and disposition of the SGLT2 inhibitor bexagliflozin in rats, monkeys and humans.

المؤلفون: Zhang, Wenbin, Li, Xiaoyan, Ding, Haifeng, Lu, Yuan, Stilwell, Geoff E., Halvorsen, Yuan-Di, Welihinda, Ajith

المصدر: Xenobiotica; May2020, Vol. 50 Issue 5, p559-569, 11p

مصطلحات موضوعية: HYPOGLYCEMIC agents, MONKEYS, METABOLISM, MACAQUES, HUMAN beings, LIVER microsomes, SPRAGUE Dawley rats

17

Academic Journal

The adenosine metabolite inosine is a functional agonist of the adenosine A2A receptor with a unique signaling bias

المؤلفون: Welihinda, Ajith A., Kaur, Manmeet, Greene, Kelly, Zhai, Yongjiao, Amento, Edward P.

المساهمون: NIH

المصدر: Cellular Signalling ; volume 28, issue 6, page 552-560 ; ISSN 0898-6568

الاتاحة: http://dx.doi.org/10.1016/j.cellsig.2016.02.010
https://api.elsevier.com/content/article/PII:S0898656816300353?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0898656816300353?httpAccept=text/plain

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18

Academic Journal

The Small Molecule Aldehyde Trap NS2 Exhibits Potent Anti-Inflammatory Activity in Three Murine Models of Inflammation

المؤلفون: Cullen, Valerie C., Mechanic, Jordan, Welihinda, Ajith, Young, Scott L., Amento, Edward P.

المصدر: Journal of Allergy and Clinical Immunology ; volume 135, issue 2, page AB384 ; ISSN 0091-6749

الاتاحة: http://dx.doi.org/10.1016/j.jaci.2014.12.1884
https://api.elsevier.com/content/article/PII:S0091674914036847?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0091674914036847?httpAccept=text/plain

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19

Academic Journal

Design, Synthesis, and Biological Evaluation of Deuterated C-Aryl Glycoside as a Potent and Long-Acting Renal Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes

المؤلفون: Xu, Ge, Lv, Binhua, Roberge, Jacques Y., Xu, Baihua, Du, Jiyan, Dong, Jiajia, Chen, Yuanwei, Peng, Kun, Zhang, Lili, Tang, Xinxing, Feng, Yan, Xu, Min, Fu, Wei, Zhang, Wenbin, Zhu, Liangcheng, Deng, Zhongping, Sheng, Zelin, Welihinda, Ajith, Sun, Xun

المصدر: Journal of Medicinal Chemistry ; volume 57, issue 4, page 1236-1251 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/jm401780b
https://pubs.acs.org/doi/pdf/10.1021/jm401780b

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20

Academic Journal

EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA1c levels in db/db mice and prolongs the survival of stroke-prone rats

المؤلفون: Zhang, Wenbin, Welihinda, Ajith, Mechanic, Jordan, Ding, Haifeng, Zhu, Liangcheng, Lu, Yuan, Deng, Zhongping, Sheng, Zelin, Lv, Binhua, Chen, Yuanwei, Roberge, Jacques Y., Seed, Brian, Wang, Yong-Xiang

المصدر: Pharmacological Research ; volume 63, issue 4, page 284-293 ; ISSN 1043-6618

الاتاحة: http://dx.doi.org/10.1016/j.phrs.2011.01.001
https://api.elsevier.com/content/article/PII:S1043661811000041?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1043661811000041?httpAccept=text/plain

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