المؤلفون: Adam R. Root, Wei Cao, Bilian Li, Peter LaPan, Caryl Meade, Jocelyn Sanford, Macy Jin, Cliona O’Sullivan, Emma Cummins, Matthew Lambert, Alfredo D. Sheehan, Weijun Ma, Scott Gatto, Kelvin Kerns, Khetemenee Lam, Aaron M. D’Antona, Lily Zhu, William A. Brady, Susan Benard, Amy King, Tao He, Lisa Racie, Maya Arai, Dianah Barrett, Wayne Stochaj, Edward R. LaVallie, James R. Apgar, Kristine Svenson, Lidia Mosyak, Yinhua Yang, Gurunadh R. Chichili, Liqin Liu, Hua Li, Steve Burke, Syd Johnson, Ralph Alderson, William J. J. Finlay, Laura Lin, Stéphane Olland, William Somers, Ezio Bonvini, Hans-Peter Gerber, Chad May, Paul A. Moore, Lioudmila Tchistiakova, Laird Bloom

المصدر: Antibodies, Vol 5, Iss 1, p 6 (2016)

مصطلحات موضوعية: P-cadherin, bispecific, cancer, immuno-oncology, T-cell, re-targeting, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://www.mdpi.com/2073-4468/5/1/6; https://doaj.org/toc/2073-4468

URL الوصول: https://doaj.org/article/8c0c6589f19a4745bedbcd5e1b1c60a5

المؤلفون: Orla Cunningham, Eric Sousa, Susan Benard, Yongjing Guo, C.M. Francis, Puja Sapra, Laura Lin, Lindsay King, Fang Jin, Weijun Ma, Aaron M. D’Antona, Nicole Piche-Nicholas, Sinead E. Keating, Sara Hanscom, Gurkan Guntas, Wayne Stochaj, Khetemcnee Lam, Claire Hendershot, Liliana Wroblewska, H. Lily Zhu, Kimberly Ann Marquette, Kristine Svenson, Divya Mathur, Fernando Narciandi, Yan Liu, Weili Duan, Edward R. Lavallie, Alison Betts, Rosemary Lawrence-Henderson, Chang Chew Shun, Adam Root, Maya Arai, Madan Katragadda, Amy King, Amy Tam, Jatin Narula, Jason Wade, Kerry Kelleher, Lioudmila Tchistiakova, Lidia Mosyak, Alfredo Darmanin Sheehan, Han Yang, Yan Zhang, James R. Apgar, Edward Rosfjord, Laird Bloom, Caryl L. Meade, Matthew McKenna

المصدر: mAbs
article-version (VoR) Version of Record

مصطلحات موضوعية: Bispecific antibody, CD3 Complex, T cell, CD3, T-Lymphocytes, Immunology, Receptors, Enterotoxin, Protein Engineering, Immunotherapy, Adoptive, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Report, Antibodies, Bispecific, developability, medicine, Immunology and Allergy, Animals, Humans, T-BsAb, T cell bispecific, immuno-oncology, Guanlyate cyclase 2c (GCC), 030304 developmental biology, 0303 health sciences, Mice, Inbred BALB C, Hybridomas, biology, antibody engineering, Chemistry, high-throughput protein production, PF-07062119, Macaca fascicularis, medicine.anatomical_structure, GUCY2C, 030220 oncology & carcinogenesis, Retargeting, biology.protein, Cancer research, antibody optimization, Female, T cell retargeting, Single-Chain Antibodies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c6dd5658cfd24d66b5b31b6d32bf8c
https://pubmed.ncbi.nlm.nih.gov/33459147

المؤلفون: William S. Somers, Lydia Mosyak, Orla Cunningham, Chao Tu, Amy Tam, Brian J. Fennell, Joel Bard, Edward R. Lavallie, Mark Stahl, Wayne Stochaj, Laura Lin, William J.J. Finlay, Virginie Terraube

المصدر: Journal of Biological Chemistry. 291:1267-1276

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein Conformation, Recombinant Fusion Proteins, Mutant, Antibody Affinity, Mutagenesis (molecular biology technique), chemical and pharmacologic phenomena, Antigen-Antibody Complex, Computational biology, Complementarity determining region, Protein aggregation, medicine.disease_cause, Biochemistry, law.invention, Protein Aggregates, 03 medical and health sciences, Protein structure, X-Ray Diffraction, Antibody Specificity, law, medicine, Humans, Molecular Biology, Biological Products, Mutation, Protein Stability, Chemistry, Cell Biology, respiratory system, Chemokine CXCL13, Complementarity Determining Regions, Recombinant Proteins, Kinetics, 030104 developmental biology, Amino Acid Substitution, Solubility, Protein Structure and Folding, Recombinant DNA, Binding Sites, Antibody, Single-Chain Antibodies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261c02617c3e30bb3256d94b8c8a3cef
https://doi.org/10.1074/jbc.m115.688010

المؤلفون: Margaret Hirschfield, Ken Dower, Vikram R. Rao, Capucine Picard, Jean-Laurent Casanova, Marshall M. Siegel, Anne Puel, Robert M. Czerwinski, Leah Cushing, Quentin G. Wright, Wayne Stochaj, Lih-Ling Lin

المصدر: Journal of Biological Chemistry. 289:10865-10875

مصطلحات موضوعية: Insecta, MAP Kinase Signaling System, Protein Conformation, Immunology, Molecular Sequence Data, Mitogen-activated protein kinase kinase, Biochemistry, Gene Expression Regulation, Enzymologic, Monocytes, MAP2K7, Open Reading Frames, Animals, Humans, ASK1, Amino Acid Sequence, Cloning, Molecular, Enzyme Inhibitors, Phosphorylation, Kinase activity, Molecular Biology, Skin, MAPK14, Cell-Free System, MAP kinase kinase kinase, biology, Interleukin-6, Cyclin-dependent kinase 4, Toll-Like Receptors, NF-kappa B, Receptors, Interleukin-1, Cell Biology, Fibroblasts, Molecular biology, Immunity, Innate, Cell biology, HEK293 Cells, Interleukin-1 Receptor-Associated Kinases, Mutation, biology.protein, Cytokines, Cyclin-dependent kinase 9, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07f0b375f92067f483c6dae8009fc78
https://doi.org/10.1074/jbc.m113.544809

المؤلفون: Desiree H.H. Tsao, Arthur Lee, Lori Krim Gavrin, Franklin J. Moy, Zhang Bao Xu, John C. McKew, Lidia Mosyak, Elizabeth Kieras, Wayne Stochaj, Annette Sievers

المصدر: Journal of Medicinal Chemistry. 53:1238-1249

مصطلحات موضوعية: Models, Molecular, Binding Sites, Magnetic Resonance Spectroscopy, Molecular Structure, Protein Conformation, Kinase, Chemistry, Electron Spin Resonance Spectroscopy, Crystallography, X-Ray, Pyrazolopyrimidine, Paramagnetism, chemistry.chemical_compound, Adenosine Triphosphate, Nuclear magnetic resonance, Drug Discovery, Humans, Molecular Medicine, Spin Labels, Protein Kinase Inhibitors, Protein Kinases, Protein Binding, Proto-oncogene tyrosine-protein kinase Src

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f003cb00b2d9a32bb90459fe0d5ba83c
https://doi.org/10.1021/jm901525b

المؤلفون: Mark Stahl, David V. Erbe, Yan-Ling Zhang, James Tobin, Xiaotian Zhong, Ron Kriz, Zheni Gjoka, Vipin Suri, Wayne Stochaj, Yuanhong Li

المصدر: Archives of Biochemistry and Biophysics. 483:45-54

مصطلحات موضوعية: Biophysics, 11β hsd1, Dehydrogenase, In Vitro Techniques, Biology, Transfection, Gluconates, Biochemistry, Catalysis, Cell Line, Substrate Specificity, Insulin resistance, 11-beta-Hydroxysteroid Dehydrogenase Type 1, medicine, Humans, Directionality, RNA, Small Interfering, Glucocorticoids, Molecular Biology, DNA Primers, chemistry.chemical_classification, Base Sequence, Endoplasmic reticulum, medicine.disease, Recombinant Proteins, Kinetics, Enzyme, chemistry, Mutagenesis, Site-Directed, Carbohydrate Dehydrogenases, RNA Interference, hormones, hormone substitutes, and hormone antagonists, Glucocorticoid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250c3463a9419817e27cb12536473b79
https://doi.org/10.1016/j.abb.2008.12.004

المؤلفون: Mark Stahl, Tony Awad, Ron Kriz, Lora Cameron-Landis, Jennifer Pocas, Xiaotian Zhong, Wayne Stochaj

المصدر: The FASEB Journal. 23

مصطلحات موضوعية: Chemistry, PCSK9, Genetics, Extracellular, Molecular Biology, Biochemistry, Biotechnology, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::50d9e93f9c6d97768e3d266c43ab5232
https://doi.org/10.1096/fasebj.23.1_supplement.lb259

المؤلفون: Steven M. Riddle, Eugene L. Brown, Vasanti S. Anand, Richard Somberg, Kerry Kelleher, Pooja Pungaliya, Wayne Stochaj, Warren D. Hirst, Peter H. Reinhart, Steven P. Braithwaite, Weili Duan, Kerri Lipinski, Laurie J. Reichling

المصدر: The FEBS journal. 276(2)

مصطلحات موضوعية: Time Factors, Gene Expression, Protein Serine-Threonine Kinases, MAP3K7, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Biochemistry, MAP2K7, Inhibitory Concentration 50, TANK-binding kinase 1, Kinase activity, Phosphorylation, Molecular Biology, Protein Kinase Inhibitors, biology, Cyclin-dependent kinase 4, Cyclin-dependent kinase 2, Cell Biology, LRRK2, nervous system diseases, Enzyme Activation, Spectrometry, Fluorescence, Mutation, biology.protein, Cyclin-dependent kinase 9, Baculoviridae

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5050abbf28183f941c26ca55054721
https://pubmed.ncbi.nlm.nih.gov/19076219

المؤلفون: Matej Orešič, Eric K. Neumann, Jack T. W. E. Vogels, Thomas N. Plasterer, Noubar B. Afeyan, Stephen Naylor, Fred E. Regnier, Clary B. Clish, Philip Snell, Xiang Zhang, Aram Adourian, Jan van der Greef, Tom Londo, Gary Lavine, Louis M. Havekes, Wayne Stochaj, Nicole M. Morel, Eugene Davidov, Elwin Verheij, Michael Meys

المساهمون: TNO Preventie en Gezondheid

المصدر: Clish, C B, Davidov, E, Orešič, M, Plasterer, T N, Lavine, G, Londo, T, Meys, M, Snell, P, Stochaj, W, Adourian, A, Zhang, X, Morel, N, Neumann, E, Verheij, E, Vogels, J T W E, Havekes, L M, Afeyan, N, Regnier, F, van der Greef, J & Naylor, S 2004, ' Integrative biological analysis of the APOE*3-leiden transgenic mouse ', OMICS: A Journal of Integrative Biology, vol. 8, no. 1, pp. 3-13 . https://doi.org/10.1089/153623104773547453
OMICS A Journal of Integrative Biology, 1, 8, 3-13

مصطلحات موضوعية: Apolipoprotein E, Apolipoprotein B, Mouse, Arteriosclerosis, Apolipoprotein E3, Receptors, Cytoplasmic and Nuclear, Biochemistry, Gene, Animal tissue, Mass Spectrometry, Mice, Gene expression, Trypsin, Chromatography, High Pressure Liquid, Oligonucleotide Array Sequence Analysis, Genome, Lysophosphatidylcholine, Messenger RNA, Lipid, Liver, Mammalia, Molecular Medicine, Liver protein, Biotechnology, Genetically modified mouse, Transgene, Principal component analysis, Mice, Transgenic, Biology, Fatty Acid-Binding Proteins, Triacylglycerol, Models, Biological, Fatty acid-binding protein, Apolipoproteins E, Transgenic mouse, Genetics, Fatty acid binding protein, Animalia, Mus musculus, Animals, Humans, Biology Pharmacology, Biomedical research, Animal model, RNA, Messenger, Molecular Biology, Analytical research, Protein, Wild type, Lysophosphatidylcholines, DNA, Nonhuman, Lipid Metabolism, Molecular biology, Multivariate Analysis, biology.protein, RNA, Carrier Proteins, Peroxisome proliferator activated receptor alpha, Controlled study, High performance liquid chromatography, Chromatography, Liquid, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21eb7ce8d0801278db4257c2343f33d
https://pubmed.ncbi.nlm.nih.gov/15107233

المؤلفون: Matej Orešič, Eric K. Neumann, Jack T. W. E. Vogels, Michael Meys, Louis M. Havekes, Mark Johnston, Gary Lavine, Eugene Davidov, Clary B. Clish, Edward W. Marple, Stephen Naylor, Thomas N. Plasterer, Aram Adourian, Jan van der Greef, Nicole M. Morel, Wayne Stochaj, Xiang Zhang, Philip Snell, Elwin Verheij, Thomas R Londo

المساهمون: TNO Preventie en Gezondheid

المصدر: Davidov, E, Clish, C B, Orešič, M, Meys, M, Stochaj, W, Snell, P, Lavine, G, Londo, T R, Adourian, A, Zhang, X, Johnston, M, Morel, N, Marple, E W, Plasterer, T N, Neumann, E, Verheij, E, Vogels, J T W E, Havekes, L M, Van Der Greef, J & Naylor, S 2004, ' Methods for the differential integrative Omic analysis of plasma from a transgenic disease animal model ', OMICS: A Journal of Integrative Biology, vol. 8, no. 4, pp. 267-288 . https://doi.org/10.1089/omi.2004.8.267
OMICS A Journal of Integrative Biology, 4, 8, 267-288
Scopus-Elsevier

مصطلحات موضوعية: Apolipoprotein E, Male, Hyperlipoproteinemias, Magnetic Resonance Spectroscopy, Time Factors, Mouse, Arteriosclerosis, Apolipoprotein E3, Metabolite, Gene mutation, Biochemistry, Mass Spectrometry, Plasma, Mice, Information processing, Trypsin, Quantitative analysis, Organism, Genes, Dominant, Genetics, Principal Component Analysis, Correlation analysis, Lipid, Genetically modified organism, Genetic Techniques, Molecular Medicine, Female, DNA modification, Biotechnology, Genetically modified mouse, Transgene, Lipoproteins, Computer program, Mice, Transgenic, Biology, Apolipoproteins E, Transgenic mouse, Metabolic regulation, Analytic method, Animals, Humans, Biomedical research, Animal model, Animal experiment, Molecular Biology, Gene, Analytical research, Crosses, Genetic, Lipoprotein metabolism, Protein, Proteins, Nonhuman, Lipid Metabolism, Mice, Inbred C57BL, Multivariate analysis, Multivariate Analysis, Mutation, Peptides, Quantitative analysis (chemistry), Controlled study, Software, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b32ef3ca299e2524a6ee251d106bbbe
https://cris.vtt.fi/en/publications/d2b25dbd-c357-4f00-acd4-97747d53bf89

المؤلفون: Eugene Davidov, Clary B. Clish, Matej Oresic, Michael Meys, Wayne Stochaj, Philip Snell, Gary Lavine, Thomas R. Londo, Aram Adourian, Xiang Zhang, Mark Johnston, Nicole Morel, Edward W. Marple, Thomas N. Plasterer, Eric Neumann, Elwin Verheij, Jack T.W.E. Vogels, Louis M. Havekes, Jan Van Der Greef, Stephen Naylor

المصدر: OMICS: A Journal of Integrative Biology; Winter2004, Vol. 8 Issue 4, p267-288, 22p

المؤلفون: Clary B. Clish, Eugene Davidov, Matej Oresic, Thomas N. Plasterer, Gary Lavine, Tom Londo, Michael Meys, Philip Snell, Wayne Stochaj, Aram Adourian, Xiang Zhang, Nicole Morel, Eric Neumann, Elwin Verheij, Jack T.W.E. Vogels, Louis M. Havekes, Noubar Afeyan, Fred Regnier, Jan Van Der Greef, Stephen Naylor

المصدر: OMICS: A Journal of Integrative Biology; Jan2004, Vol. 8 Issue 1, p3-13, 11p