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1Academic Journal
المؤلفون: Laleu, Benoît, Rubiano, Kelly, Yeo, Tomas, Hallyburton, Irene, Anderson, Mark, Crespo-Fernandez, Benigno, Gamo, Francisco-Javier, Antonova-Koch, Yevgeniya, Orjuela-Sanchez, Pamela, Wittlin, Sergio, Jana, Gouranga, Maity, Bikash, Chenu, Elodie, Duffy, James, Sjö, Peter, Waterson, David, Winzeler, Elizabeth, Guantai, Eric, Fidock, David, Hansson, Thomas
المصدر: ChemMedChem. 17(22)
مصطلحات موضوعية: Malaria, PfeEF2, biological activity, drug discovery, malaria rate of killing, malaria resistance, Humans, Antimalarials, Plasmodium falciparum, Malaria, Falciparum, Malaria
وصف الملف: application/pdf
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2Academic Journal
المؤلفون: Jiménez-Díaz, María Belén, Ebert, Daniel, Salinas, Yandira, Pradhan, Anupam, Lehane, Adele M, Myrand-Lapierre, Marie-Eve, O’Loughlin, Kathleen G, Shackleford, David M, de Almeida, Mariana Justino, Carrillo, Angela K, Clark, Julie A, Dennis, Adelaide SM, Diep, Jonathon, Deng, Xiaoyan, Duffy, Sandra, Endsley, Aaron N, Fedewa, Greg, Guiguemde, W Armand, Gómez, María G, Holbrook, Gloria, Horst, Jeremy, Kim, Charles C, Liu, Jian, Lee, Marcus CS, Matheny, Amy, Martínez, María Santos, Miller, Gregory, Rodríguez-Alejandre, Ane, Sanz, Laura, Sigal, Martina, Spillman, Natalie J, Stein, Philip D, Wang, Zheng, Zhu, Fangyi, Waterson, David, Knapp, Spencer, Shelat, Anang, Avery, Vicky M, Fidock, David A, Gamo, Francisco-Javier, Charman, Susan A, Mirsalis, Jon C, Ma, Hongshen, Ferrer, Santiago, Kirk, Kiaran, Angulo-Barturen, Iñigo, Kyle, Dennis E, DeRisi, Joseph L, Floyd, David M, Guy, R Kiplin
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 111(50)
مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Antimicrobial Resistance, Infectious Diseases, Orphan Drug, Rare Diseases, Malaria, Vector-Borne Diseases, 2.1 Biological and endogenous factors, 2.2 Factors relating to the physical environment, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Antimalarials, Calcium-Transporting ATPases, Cellular Senescence, Drug Discovery, Drug Resistance, Erythrocytes, Flow Cytometry, Heterocyclic Compounds, 4 or More Rings, High-Throughput Screening Assays, Isoquinolines, Models, Molecular, Molecular Structure, Plasmodium, malaria, PfATP4, drug discovery
وصف الملف: application/pdf
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3Academic Journal
المؤلفون: Norcross, Neil, Wilson, Caroline, Baragana, Beatriz, Hallyburton, Irene, Osuna-Cabello, Maria, Norval, Suzanne, Riley, Jennifer, Fletcher, Daniel, Sinden, Robert, Delves, Michael J., Ruecker, Andrea, Duffy, Sandra, Meister, Stephan, Antonova-Koch, Yevgeniya, Crespo, Benigno, de Cózar, Cristina, Sanz, Laura, Gamo, Francisco-Javier, Avery, Vicky M., Frearson, Julie A., Gray, David, Fairlamb, Alan, Winzeler, Elizabeth A., Waterson, David, Campbell, Simon F., Willis, Paul, Read, Kevin, Gilbert, Ian
المصدر: Norcross , N , Wilson , C , Baragana , B , Hallyburton , I , Osuna-Cabello , M , Norval , S , Riley , J , Fletcher , D , Sinden , R , Delves , M J , Ruecker , A , Duffy , S , Meister , S , Antonova-Koch , Y , Crespo , B , de Cózar , C , Sanz , L , Gamo , F-J , Avery , V M , Frearson , J A , Gray , D , Fairlamb , A , Winzeler , E A , Waterson , ....
مصطلحات موضوعية: Plasmodium falciparum, aminoacetamides, antimalarial agents, hit optimization, malaria, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/3000, Toxicology and Pharmaceutics(all), /dk/atira/pure/subjectarea/asjc/1600/1605, name=Organic Chemistry
وصف الملف: application/pdf
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4Academic Journal
المؤلفون: Norcross, Neil R, Wilson, Caroline, Baragaña, Beatriz, Hallyburton, Irene, Osuna-Cabello, Maria, Norval, Suzanne, Riley, Jennifer, Fletcher, Daniel, Sinden, Robert, Delves, Michael, Ruecker, Andrea, Duffy, Sandra, Meister, Stephan, Antonova-Koch, Yevgeniya, Crespo, Benigno, de Cózar, Cristina, Sanz, Laura M, Gamo, Francisco Javier, Avery, Vicky M, Frearson, Julie A, Gray, David W, Fairlamb, Alan H, Winzeler, Elizabeth A, Waterson, David, Campbell, Simon F, Willis, Paul A, Read, Kevin D, Gilbert, Ian H
وصف الملف: text
Relation: https://researchonline.lshtm.ac.uk/id/eprint/4655263/1/Norcross_et_al-2019-ChemMedChem.pdf; Norcross, Neil R; Wilson, Caroline; Baragaña, Beatriz; Hallyburton, Irene; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Fletcher, Daniel; Sinden, Robert; Delves, Michael ; +18 more. Ruecker, Andrea; Duffy, Sandra; Meister, Stephan; Antonova-Koch, Yevgeniya; Crespo, Benigno; de Cózar, Cristina; Sanz, Laura M; Gamo, Francisco Javier; Avery, Vicky M; Frearson, Julie A; Gray, David W; Fairlamb, Alan H; Winzeler, Elizabeth A; Waterson, David; Campbell, Simon F; Willis, Paul A; Read, Kevin D; Gilbert, Ian H; (2019) Substituted Aminoacetamides as Novel Leads for Malaria Treatment. ChemMedChem, 14 (14). pp. 1329-1335. ISSN 1860-7179 DOI: https://doi.org/10.1002/cmdc.201900329
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5Academic Journal
المؤلفون: Brunschwig, Christel, Lawrence, Nina, Taylor, Dale, Abay, Efrem, Njoroge, Mathew, Basarab, Gregory S., Le Manach, Claire, Paquet, Tanya, Cabrera, Diego Gonzàlez, Nchinda, Aloysius T., de Kock, Carmen, Wiesner, Lubbe, Denti, Paolo, Waterson, David, Blasco, Benjamin, Leroy, Didier, Witty, Michael J., Donini, Cristina, Duffy, James, Wittlin, Sergio, White, Karen L., Charman, Susan A., Jiménez-Díaz, Maria Belén, Angulo-Barturen, Iñigo, Herreros, Esperanza, Gamo, Francisco Javier, Rochford, Rosemary, Mancama, Dalu, Coetzer, Theresa L., van der Watt, Mariëtte E., Reader, Janette, Birkholtz, Lyn-Marie, Marsh, Kennan C., Solapure, Suresh M., Burke, John E., McPhail, Jacob A., Vanaerschot, Manu, Fidock, David A., Fish, Paul V., Siegl, Peter, Smith, Dennis A., Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N., Marfurt, Jutta, Silue, Kigbafori D., Street, Leslie J., Chibale, Kelly
وصف الملف: application/pdf
Relation: https://edoc.unibas.ch/65596/1/20180925140908_5baa2564af088.pdf; Brunschwig, Christel and Lawrence, Nina and Taylor, Dale and Abay, Efrem and Njoroge, Mathew and Basarab, Gregory S. and Le Manach, Claire and Paquet, Tanya and Cabrera, Diego Gonzàlez and Nchinda, Aloysius T. and de Kock, Carmen and Wiesner, Lubbe and Denti, Paolo and Waterson, David and Blasco, Benjamin and Leroy, Didier and Witty, Michael J. and Donini, Cristina and Duffy, James and Wittlin, Sergio and White, Karen L. and Charman, Susan A. and Jiménez-Díaz, Maria Belén and Angulo-Barturen, Iñigo and Herreros, Esperanza and Gamo, Francisco Javier and Rochford, Rosemary and Mancama, Dalu and Coetzer, Theresa L. and van der Watt, Mariëtte E. and Reader, Janette and Birkholtz, Lyn-Marie and Marsh, Kennan C. and Solapure, Suresh M. and Burke, John E. and McPhail, Jacob A. and Vanaerschot, Manu and Fidock, David A. and Fish, Paul V. and Siegl, Peter and Smith, Dennis A. and Wirjanata, Grennady and Noviyanti, Rintis and Price, Ric N. and Marfurt, Jutta and Silue, Kigbafori D. and Street, Leslie J. and Chibale, Kelly. (2018) UCT943, a next generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria. Antimicrobial agents and chemotherapy, 62 (9). e00012-e00018.; info:pmid/29941635; urn:ISSN:0066-4804; urn:ISSN:1098-6596
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6Academic Journal
المؤلفون: Kokkonda, Sreekanth, El Mazouni, Farah, White, Karen L., White, John, Shackleford, David M., Lafuente-Monasterio, Maria Jose, Manjalanagara, Krishne, Joseph, Jayan T., Garcia-Pérez, Adolfo, Fernandez, Jorge, Gamo, Francisco Javier, Waterson, David, Burrows, Jeremy N., Palmer, Michael J., Charman, Susan A., Rathod, Pradipsinh K., Phillips, Margaret A.
المصدر: Kokkonda , S , El Mazouni , F , White , K L , White , J , Shackleford , D M , Lafuente-Monasterio , M J , Manjalanagara , K , Joseph , J T , Garcia-Pérez , A , Fernandez , J , Gamo , F J , Waterson , D , Burrows , J N , Palmer , M J , Charman , S A , Rathod , P K & Phillips , M A 2018 , ' Isoxazolopyrimidine-Based Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Antimalarial Activity ' , ACS Omega , vol. 3 , ....
وصف الملف: application/pdf
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7Academic Journal
المؤلفون: Brunschwig, Christel, Lawrence, Nina, Taylor, Dale, Abay, Efrem, Njoroge, Mathew, Basarab, Gregory S., Le Manach, Claire, Paquet, Tanya, Gonzàlez Cabrera, Diego, Nchinda, Aloysius T., de Kock, Carmen, Wiesner, Lubbe, Denti, Paolo, Waterson, David, Blasco, Benjamin, Leroy, Didier, Witty, Michael J., Donini, Cristina, Duffy, James, Wittlin, Sergio, White, Karen L., Charman, Susan A., Jiménez-Díaz, Maria Belén, Angulo-Barturen, Iñigo, Herreros, Esperanza, Gamo, Francisco Javier, Rochford, Rosemary, Mancama, Dalu, Coetzer, Theresa L., van der Watt, Mariëtte E., Reader, Janette, Birkholtz, Lyn Marie, Marsh, Kennan C., Solapure, Suresh M., Burke, John E., McPhail, Jacob A., Vanaerschot, Manu, Fidock, David A., Fish, Paul V., Siegl, Peter, Smith, Dennis A., Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N., Marfurt, Jutta, Silue, Kigbafori D., Street, Leslie J., Chibale, Kelly
المصدر: Brunschwig , C , Lawrence , N , Taylor , D , Abay , E , Njoroge , M , Basarab , G S , Le Manach , C , Paquet , T , Gonzàlez Cabrera , D , Nchinda , A T , de Kock , C , Wiesner , L , Denti , P , Waterson , D , Blasco , B , Leroy , D , Witty , M J , Donini , C , Duffy , J , Wittlin , S , White , K L , Charman , S A , Jiménez-Díaz , M ....
وصف الملف: application/pdf
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8Academic Journal
المؤلفون: Paquet, Tanya, Le Manach, Claire, Cabrera, Diego González, Younis, Yassir, Henrich, Philipp P., Abraham, Tara S., Lee, Marcus C.S., Basak, Rajshekhar, Ghidelli-Disse, Sonja, Lafuente-Monasterio, María José, Bantscheff, Marcus, Ruecker, Andrea, Blagborough, Andrew M., Zakutansky, Sara E., Zeeman, Anne Marie, White, Karen L., Shackleford, David M., Mannila, Janne, Morizzi, Julia, Scheurer, Christian, Angulo-Barturen, Iñigo, Santosmartínez, María, Ferrer, Santiago, Sanz, Laura María, Gamo, Francisco Javier, Reader, Janette, Botha, Mariette, Dechering, Koen J., Sauerwein, Robert W., Tungtaeng, Anchalee, Vanachayangkul, Pattaraporn, Lim, Chek Shik, Burrows, Jeremy, Witty, Michael J., Marsh, Kennan C., Bodenreider, Christophe, Rochford, Rosemary, Solapure, Suresh M., Jiménez-Díaz, María Belén, Wittlin, Sergio, Charman, Susan A., Donini, Cristina, Campo, Brice, Birkholtz, Lyn Marie, Khanson, Kirsten, Drewes, Gerard, Kocken, Clemensh M., Delves, Michael J., Leroy, Didier, Fidock, David A., Waterson, David, Street, Leslie J., Chibale, Kelly
المصدر: Paquet , T , Le Manach , C , Cabrera , D G , Younis , Y , Henrich , P P , Abraham , T S , Lee , M C S , Basak , R , Ghidelli-Disse , S , Lafuente-Monasterio , M J , Bantscheff , M , Ruecker , A , Blagborough , A M , Zakutansky , S E , Zeeman , A M , White , K L , Shackleford , D M , Mannila , J , Morizzi , J , Scheurer , C , Angulo-Barturen , I , Santosmartínez , M ....
مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/2700/2700, name=General Medicine
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9Academic Journal
المؤلفون: Hallyburton, Irene, Grimaldi, Raffaella, Woodland, Andrew, Baragana, Beatriz, Luksch, Torsten, Spinks, Daniel, James, Daniel, Leroy, Didier, Waterson, David, Fairlamb, Alan H., Wyatt, Paul G., Gilbert, Ian H., Frearson, Julie A.
المصدر: Hallyburton , I , Grimaldi , R , Woodland , A , Baragana , B , Luksch , T , Spinks , D , James , D , Leroy , D , Waterson , D , Fairlamb , A H , Wyatt , P G , Gilbert , I H & Frearson , J A 2017 , ' Screening a protein kinase inhibitor library against Plasmodium falciparum ' , Malaria Journal , vol. 16 , 446 , pp. 1-11 . https://doi.org/10.1186/s12936-017-2085-4
وصف الملف: application/pdf
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10Academic Journal
المؤلفون: Baragaña, Beatriz, Norcross, Neil R., Wilson, Caroline, Porzelle, Achim, Hallyburton, Irene, Grimaldi, Raffaella, Osuna-Cabello, Maria, Norval, Suzanne, Riley, Jennifer, Stojanovski, Laste, Simeons, Frederick R. C., Wyatt, Paul G., Delves, Michael J., Meister, Stephan, Duffy, Sandra, Avery, Vicky M., Winzeler, Elizabeth A., Sinden, Robert E., Wittlin, Sergio, Frearson, Julie A., Gray, David W., Fairlamb, Alan H., Waterson, David, Campbell, Simon F., Willis, Paul, Read, Kevin D., Gilbert, Ian H.
المصدر: Baragaña , B , Norcross , N R , Wilson , C , Porzelle , A , Hallyburton , I , Grimaldi , R , Osuna-Cabello , M , Norval , S , Riley , J , Stojanovski , L , Simeons , F R C , Wyatt , P G , Delves , M J , Meister , S , Duffy , S , Avery , V M , Winzeler , E A , Sinden , R E , Wittlin , S , Frearson , J A , Gray , D W , Fairlamb , A H , ....
وصف الملف: application/pdf
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11Academic Journal
المؤلفون: Norcross, Neil R., Baragana, Beatriz, Wilson, Caroline, Hallyburton, Irene, Osuna-Cabello, Maria, Norval, Suzanne, Riley, Jennifer, Stojanovski, Laste, Simeons, Frederick R. C., Porzelle, Achim, Grimaldi, Raffaella, Wittlin, Sergio, Duffy, Sandra, Avery, Vicky M., Meister, Stephan, Sanz, Laura, Jimenez-Diaz, Belen, Angulo-Barturen, Inigo, Ferrer, Santiago, Santos Marinez, Maria, Javier Gamo, Francisco, Frearson, Julie A., Gray, David W., Fairlamb, Alan H., Winzeler, Elizabeth A., Waterson, David, Campbell, Simon F., Willis, Paul, Read, Kevin D., Gilbert, Ian H.
المصدر: Norcross , N R , Baragana , B , Wilson , C , Hallyburton , I , Osuna-Cabello , M , Norval , S , Riley , J , Stojanovski , L , Simeons , F R C , Porzelle , A , Grimaldi , R , Wittlin , S , Duffy , S , Avery , V M , Meister , S , Sanz , L , Jimenez-Diaz , B , Angulo-Barturen , I , Ferrer , S , Santos Marinez , M , Javier Gamo , F , Frearson , J A , Gray , D W ....
وصف الملف: application/pdf
الاتاحة: http://discovery.dundee.ac.uk/portal/en/research/trisubstituted-pyrimidines-as-efficacious-and-fastacting-antimalarials(ec38528a-8996-402b-8192-3942dc9e1ee1).html
https://doi.org/10.1021/acs.jmedchem.6b00028
http://hdl.handle.net/10588/ec38528a-8996-402b-8192-3942dc9e1ee1
http://discovery.dundee.ac.uk/ws/files/8857244/MMV02_V73.pdf
http://discovery.dundee.ac.uk/ws/files/8857246/Supporting_Information_11.pdf
http://discovery.dundee.ac.uk/ws/files/9395342/acs_2Ejmedchem_2E6b00028.pdf -
12Academic Journal
المؤلفون: Kokkonda, Sreekanth, Deng, Xiaoyi, White, Karen L., Coteron, Jose M., Marco, Maria, de las Heras, Laura, White, John, El Mazouni, Farah, Tomchick, Diana R., Manjalanagara, Krishne, Rudra, Kakali Rani, Chen, Gong, Morizzi, Julia, Ryan, Eileen, Kaminsky, Werner, Leroy, Didier, Martínez-Martínez, María Santos, Jimenez-Diaz, Maria Belen, Bazaga, Santiago Ferrer, Angulo-Barturen, Iñigo, Waterson, David, Burrows, Jeremy N., Matthews, Dave, Charman, Susan A., Phillips, Margaret A., Rathod, Pradipsinh K.
المساهمون: Welch Foundation, National Institute of Allergy and Infectious Diseases, Medicines for Malaria Venture
المصدر: Journal of Medicinal Chemistry ; volume 59, issue 11, page 5416-5431 ; ISSN 0022-2623 1520-4804
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13Academic Journal
المؤلفون: Hameed P., Shahul, Solapure, Suresh, Patil, Vikas, Henrich, Philipp P., Magistrado, Pamela A., Bharath, Sowmya, Murugan, Kannan, Viswanath, Pavithra, Puttur, Jayashree, Srivastava, Abhishek, Bellale, Eknath, Panduga, Vijender, Shanbag, Gajanan, Awasthy, Disha, Landge, Sudhir, Morayya, Sapna, Koushik, Krishna, Saralaya, Ramanatha, Raichurkar, Anandkumar, Rautela, Nikhil, Roy Choudhury, Nilanjana, Ambady, Anisha, Nandishaiah, Radha, Reddy, Jitendar, Prabhakar, K. R., Menasinakai, Sreenivasaiah, Rudrapatna, Suresh, Chatterji, Monalisa, Jiménez-Díaz, María Belén, Martínez, María Santos, Sanz, Laura María, Coburn-Flynn, Olivia, Fidock, David A., Lukens, Amanda K., Wirth, Dyann F., Bandodkar, Balachandra, Mukherjee, Kakoli, McLaughlin, Robert E., Waterson, David, Rosenbrier-Ribeiro, Lyn, Hickling, Kevin, Balasubramanian, V., Warner, Peter, Hosagrahara, Vinayak, Dudley, Adam, Iyer, Pravin S., Narayanan, Shridhar, Kavanagh, Stefan, Sambandamurthy, Vasan K.
المصدر: Nature Communications ; volume 6, issue 1 ; ISSN 2041-1723
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14
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15Academic Journal
المؤلفون: Ghidelli-Disse, Sonja, Lafuente-Monasterio, Maria, Waterson, David, Witty, Michael, Younis, Yassir, Paquet, Tanya, Street, Leslie, Chibale, Kelly, Gamo-Benito, Francisco, Bantscheff, Marcus, Drewes, Gerard
المصدر: Malaria Journal ; http://www.malariajournal.com/
مصطلحات موضوعية: antimalarial drugs, resistant parasites
وصف الملف: application/pdf
Relation: http://hdl.handle.net/11427/15411; http://dx.doi.org/10.1186/1475-2875-13-S1-P38; https://open.uct.ac.za/bitstream/11427/15411/1/Ghidelli_Disse_Identification_of_Plasmodium_2014.pdf
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16Academic Journal
المؤلفون: Avery, Vicky M, Bashyam, Sridevi, Burrows, Jeremy N, Duffy, Sandra, Papadatos, George, Puthukkuti, Shyni, Sambandan, Yuvaraj, Singh, Shivendra, Spangenberg, Thomas, Waterson, David, Willis, Paul
مصطلحات موضوعية: Microbiology, Medical microbiology, Medical microbiology not elsewhere classified, Public health
Relation: Malaria Journal; http://hdl.handle.net/10072/103602
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17Academic Journal
المؤلفون: P, Shahul Hameed, Solapure, Suresh, Mukherjee, Kakoli, Nandi, Vrinda, Waterson, David, Shandil, Radha, Balganesh, Meenakshi, Sambandamurthy, Vasan K., Raichurkar, Anand Kumar, Deshpande, Abhijeet, Ghosh, Anirban, Awasthy, Disha, Shanbhag, Gajanan, Sheikh, Gulebahar, McMiken, Helen, Puttur, Jayashree, Reddy, Jitendar, Werngren, Jim, Read, Jon, Kumar, Mahesh, R, Manjunatha, Chinnapattu, Murugan, Madhavapeddi, Prashanti, Manjrekar, Praveena, Basu, Reetobrata, Gaonkar, Sheshagiri, Sharma, Sreevalli, Hoffner, Sven, Humnabadkar, Vaishali, Subbulakshmi, Venkita, Panduga, Vijender
المصدر: Antimicrobial Agents and Chemotherapy ; volume 58, issue 8, page 4993-4994 ; ISSN 0066-4804 1098-6596
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18
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19Academic Journal
المؤلفون: Le Manach, Claire, Scheurer, Christian, Sax, Sibylle, Schleiferbock, Sarah, Cabrera, Diego, Younis, Yassir, Paquet, Tanya, Street, Leslie, Smith, Peter, Ding, Xavier, Waterson, David, Witty, Michael, Leroy, Didier, Chibale, Kelly, Wittlin, Sergio
المصدر: Malaria Journal ; http://www.malariajournal.com/
مصطلحات موضوعية: Plasmodium falciparum, Speed of action, Stage-specificity
وصف الملف: application/pdf
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20Academic Journal
المؤلفون: BURROWS, JEREMY N, BURLOT, EMILIE, CAMPO, BRICE, CHERBUIN, STEPHANIE, JEANNERET, SARAH, LEROY, DIDIER, SPANGENBERG, THOMAS, WATERSON, DAVID, WELLS, TIMOTHY NC, WILLIS, PAUL
المصدر: Parasitology ; volume 141, issue 1, page 128-139 ; ISSN 0031-1820 1469-8161
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