المؤلفون: Sophia Gayle, Timothy Paradis, Kelli Jones, Juan Vasquez, Vishwas M Paralkar

المصدر: Immunotherapy. 14:1467-1480

مصطلحات موضوعية: Oncology, Immunology, Immunology and Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5f93baa122e2d335b91211a856d13f6b
https://doi.org/10.2217/imt-2022-0121

المؤلفون: Sophia, Gayle, Timothy, Paradis, Kelli, Jones, Juan, Vasquez, Vishwas M, Paralkar

المصدر: Immunotherapy.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a13d8e17308a95c820489fada8e45c14
https://pubmed.ncbi.nlm.nih.gov/36597724

المؤلفون: Igor Erjavec, Tatjana Bordukalo-Niksic, Jelena Brkljacic, Danka Grcevic, Gordana Mokrovic, Maja Kesic, Dunja Rogic, William Zavadoski, Vishwas M Paralkar, Lovorka Grgurevic, Vladimir Trkulja, Lipa Cicin-Sain, Slobodan Vukicevic

المصدر: PLoS ONE, Vol 11, Iss 2, p e0150102 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4764355?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/c0004ca537984a9d979b24dc010884d8

المؤلفون: Sophia Gayle, Robert Aiello, Nalin Leelatian, Jason M Beckta, Jane Bechtold, Patricia Bourassa, Johanna Csengery, Robert J Maguire, Dan Marshall, Ranjini K Sundaram, Jinny Van Doorn, Kelli Jones, Hunter Moore, Lori Lopresti-Morrow, Timothy Paradis, Laurie Tylaska, Qing Zhang, Hannah Visca, Yana K Reshetnyak, Oleg A Andreev, Donald M Engelman, Peter M Glazer, Ranjit S Bindra, Vishwas M Paralkar

المصدر: NAR Cancer. 3

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::91d0a46bfe2d131898724a672d72164e
https://doi.org/10.1093/narcan/zcab047

المؤلفون: Daniel Richard Marshall, Timothy Joseph Paradis, Ranjit S. Bindra, Vishwas M. Paralkar, Johanna Marie Csengery, Qing Zhang, Hannah M. Visca, Nalin Leelatian, Hunter Moore, Laurie Tylaska, Donald M. Engelman, Jane Bechtold, Jason M. Beckta, Sophia Gayle, Yana K. Reshetnyak, Peter M. Glazer, Patricia Bourassa, Oleg A. Andreev, Kelli Jones, Robert John Maguire, Lori Lopresti-Morrow, Robert J. Aiello, Jinny Van Doorn, Ranjini K. Sundaram

المصدر: NAR Cancer

مصطلحات موضوعية: 0301 basic medicine, AcademicSubjects/SCI01140, AcademicSubjects/SCI01060, medicine.drug_class, DNA repair, Poly ADP ribose polymerase, AcademicSubjects/SCI00030, Standard Article, AcademicSubjects/SCI01180, 03 medical and health sciences, 0302 clinical medicine, Therapeutic index, medicine, Chemistry, Cancer, General Medicine, medicine.disease, Warburg effect, 030104 developmental biology, 030220 oncology & carcinogenesis, PARP inhibitor, Cancer research, AcademicSubjects/SCI00980, Corrigendum, Topoisomerase inhibitor, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641a346869b65a66c91c777023c8a97b
http://europepmc.org/articles/PMC8210154

المؤلفون: Amy Brault, Vishwas M. Paralkar, Slobodan Vukicevic, Fran Borovečki, Ivo Dumić-Čule, Martina Pauk, Jelena Brkljacic, Lovorka Grgurevic, Tatjana Bordukalo-Niksic

المصدر: Acta Diabetologica

مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Bone Morphogenetic Protein 6, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Mice, Obese, 030209 endocrinology & metabolism, CHO Cells, 030204 cardiovascular system & hematology, Carbohydrate metabolism, Diabetes Mellitus, Experimental, Mice, 03 medical and health sciences, Cricetulus, 0302 clinical medicine, Endocrinology, Downregulation and upregulation, Cricetinae, Internal medicine, Internal Medicine, medicine, Insulin, Animals, Homeostasis, Glucose homeostasis, Bone morphogenetic protein 6 (BMP6), Receptor, Cells, Cultured, Chemistry, General Medicine, Ob/ob mice, Recombinant Proteins, Rats, Bone morphogenetic protein 6, Glucose, Diabetes Mellitus, Type 2, Gluconeogenesis, PepCK, Original Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c2f82128a1f241112b77073860a030
https://doi.org/10.1007/s00592-018-1265-1

المؤلفون: Qing Zhang, William J. Zavadoski, Robert J. Aiello, M.C. Holt, Nicole Barucci, Jim Valentine, A.J. Stein, Vishwas M. Paralkar, Stéphane De Lombaert, Daniel R. Goldberg, Patricia Bourassa

المصدر: Bioorganic & Medicinal Chemistry Letters. 27:413-419

مصطلحات موضوعية: 0301 basic medicine, Serotonin, Proline, Clinical Biochemistry, Pharmaceutical Science, Tryptophan Hydroxylase, Pharmacology, Biochemistry, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, 03 medical and health sciences, Dogs, 0302 clinical medicine, Oral administration, In vivo, Drug Discovery, Animals, Humans, Prodrugs, Spiro Compounds, Intestinal Mucosa, Molecular Biology, Binding Sites, TPH1, Chemistry, Organic Chemistry, Prodrug, Tryptophan hydroxylase, Oxidoreductase inhibitor, Protein Structure, Tertiary, Rats, Intestines, Molecular Docking Simulation, Pyrimidines, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d832bfe964546651027bc5ad2f1478f
https://doi.org/10.1016/j.bmcl.2016.12.053

المؤلفون: Nicole Barucci, Stéphane De Lombaert, Vishwas M. Paralkar, Jim Valentine, William J. Zavadoski, Patricia Bourassa, Robert J. Aiello, A.J. Stein, Daniel R. Goldberg, Qing Zhang

المصدر: Bioorganic & Medicinal Chemistry Letters. 26:2855-2860

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Tryptophan Hydroxylase, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Biosynthesis, Drug Discovery, Humans, Structure–activity relationship, Enzyme Inhibitors, Guanidine, Molecular Biology, 5-HT receptor, TPH1, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Tryptophan hydroxylase, Oxidoreductase inhibitor, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Molecular Medicine, Serotonin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1fd6da7a2d3eccaf3ce69f8c5f867b
https://doi.org/10.1016/j.bmcl.2016.04.057

المؤلفون: Robert A. Volkmann, Johanna Marie Csengery, Vishwas M. Paralkar, Patricia Bourassa, Ranjit S. Bindra, Lori Lopresti-Morrow, Kelli Jones, Sophia Gayle, Qing Zhang, Robert T. Maguire, Robert J. Aiello, Timothy Joseph Paradis, Ketaki Deshpande, Jane Bechtold, Hunter Moore, Peter M. Glazer, Daniel Richard Marshall, Laurie Tylaska

المصدر: Cancer Research. 80:6242-6242

مصطلحات موضوعية: Cancer Research, Cancer, Maytansinoid, medicine.disease, Warburg effect, Small molecule, In vitro, chemistry.chemical_compound, Oncology, chemistry, Antigen, In vivo, Cancer research, medicine, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::972ae5d9fc806967f539ce7e389462d7
https://doi.org/10.1158/1538-7445.am2020-6242

المؤلفون: Sophia Gayle, Hunter Moore, Patricia Bourassa, Lori Lopresti-Morrow, Robert A. Volkmann, Vishwas M. Paralkar, Peter M. Glazer, Robert J. Aiello, Robert T. Maguire, Timothy Joseph Paradis, Ranjit S. Bindra, Jane Bechtold, Qing Zhang, Kelli Jones, Johanna Marie Csengery, Daniel Richard Marshall, Laurie Tylaska, Ketaki Deshpande

المصدر: Cancer Research. 80:6249-6249

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Chemistry, medicine.drug_class, Cancer, medicine.disease, Warburg effect, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Oncology, Antigen, In vivo, 030220 oncology & carcinogenesis, Cancer cell, medicine, Cancer research, Exatecan, Topoisomerase inhibitor, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4928c7d63e5e675b974c3302e6a34b0d
https://doi.org/10.1158/1538-7445.am2020-6249

المؤلفون: Vishwas M. Paralkar, Benjamin S. Weeks, Yu M. Yu, Hynda K. Kleinman, A. Hari Reddi

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jcb.rupress.org/content/119/6/1721.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.4533; http://jcb.rupress.org/content/119/6/1721.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.4533
http://jcb.rupress.org/content/119/6/1721.full.pdf

المؤلفون: Patricia Bourassa, Nicole Barucci, Stéphane De Lombaert, William J. Zavadoski, Daniel R. Goldberg, Qing Zhang, Robert J. Aiello, James J. Valentine, Vishwas M. Paralkar

المصدر: Bioorganic & Medicinal Chemistry Letters. 26:1124-1129

مصطلحات موضوعية: 0301 basic medicine, Serotonin, Proline, Clinical Biochemistry, Pharmaceutical Science, Tryptophan Hydroxylase, Inhibitory postsynaptic potential, Biochemistry, Inhibitory Concentration 50, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Animals, Humans, Spiro Compounds, Neurotransmitter, Molecular Biology, chemistry.chemical_classification, Binding Sites, TPH1, Aryl, Organic Chemistry, Brain, Protein Structure, Tertiary, Rats, Amino acid, Molecular Docking Simulation, 030104 developmental biology, Monoamine neurotransmitter, chemistry, Drug Design, Molecular Medicine, Half-Life, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ee42e411b02d02f0ced871cd344fd2
https://doi.org/10.1016/j.bmcl.2016.01.064

المؤلفون: Johanna Marie Csengery, Daniel Richard Marshall, Per Hellsund, Ranjit S. Bindra, Oleg A. Andreev, Peter M. Glazer, Yana K. Reshetnyak, Laurie Tylaska, Dhammika Weerakkody, Hanna Visca, Timothy Joseph Paradis, Jane Bechtold, Robert J. Aiello, Vishwas M. Paralkar, Qing Zhang, Donald M. Engelman, Anna Moshnikova, Brett S. Robinson, Gregory Slaybaugh, Patricia Bourassa, Lori Lopresti-Morrow

المصدر: Cancer Research. 79:2981-2981

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Chemotherapy, Tumor microenvironment, business.industry, medicine.medical_treatment, Cancer, medicine.disease, Radiation therapy, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, PARP inhibitor, Cancer cell, Drug delivery, medicine, Cancer research, Bone marrow, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d14574defd0d4effb1812a40ffd714e4
https://doi.org/10.1158/1538-7445.am2019-2981

المؤلفون: Vishwas M. Paralkar, Lori lopresti-Morrow, Johanna Marie Csengery, Ranjit S. Bindra, Robert J. Aiello, Daniel Richard Marshall, Per Hellsund, Patricia Bourassa, Qing Zhang, Laurie Tylaska, Jane Bechtold, Peter M. Glazer, Tim Paradis, Ranjini K. Sundaram, Brett Robinson

المصدر: Journal of Clinical Oncology. 37:e14664-e14664

مصطلحات موضوعية: Cancer Research, Tumor targeting, biology, business.industry, 03 medical and health sciences, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, PARP inhibitor, Homologous chromosome, biology.protein, Cancer research, Medicine, business, Polymerase, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7d80709ac2b0e38c95d42651578cb1af
https://doi.org/10.1200/jco.2019.37.15_suppl.e14664

المؤلفون: Jianxin Yang, Vishwas M. Paralkar, Donna Marie Stone, Tracey Clark, Yasmina Noubia Abdiche, Alison Betts, Mei Li, Michael A Giovanelli, Judith L. Treadway

المصدر: Journal of Pharmacology and Experimental Therapeutics. 333:2-13

مصطلحات موضوعية: Adult, Male, Osteoporosis, Pharmacology, Models, Biological, Rats, Sprague-Dawley, Mice, Animals, Humans, Medicine, Adverse effect, Receptor, Osteoporosis, Postmenopausal, Aged, biology, Concentration Response, business.industry, Antibodies, Monoclonal, Middle Aged, medicine.disease, In vitro, Rats, Dissociation constant, Bone Diseases, Metabolic, Macaca fascicularis, Pharmacodynamics, biology.protein, Intercellular Signaling Peptides and Proteins, Molecular Medicine, Female, Antibody, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6db23c52d9d7dce200299e7d68b9a06
https://doi.org/10.1124/jpet.109.164129

المؤلفون: Scott W. Bagley, Hang T. Nguyen, Kosea S. Frederick, Michael P. Zawistoski, Kenneth J. DiRico, Vishwas M. Paralkar, Xiaojing Yang, Hua Gao, Thanh V. Olson, Keith Riccardi, Stephanie Santucci, F. Christopher Bi, Tristan S. Maurer, Matthew Corbett, Daniel P. Walker, Ryan Michael Kelley, Robert M. Oliver, John William Benbow, David R. Healy, Joseph DiBrinno, Amit S. Kalgutkar, Kevin K.-C. Liu, Mei Li, Syed Ahmed, Mary Theresa Didiuk, Joel Morris, Chiliu Chen, William M. Hungerford, Bruce M. Bechle, Yuan Zeng, Jianke Li, Angel Guzman-Perez, David A. Griffith

المصدر: Bioorganic & Medicinal Chemistry Letters. 19:4555-4559

مصطلحات موضوعية: Male, Anabolism, Stereochemistry, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, chemistry.chemical_element, Parathyroid hormone, Stimulation, Pyrimidinones, Calcium, Biochemistry, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Anabolic Agents, Pharmacokinetics, Drug Discovery, Animals, Receptor, Molecular Biology, Trifluoromethyl, Organic Chemistry, Rats, chemistry, Parathyroid Hormone, Molecular Medicine, Calcium-sensing receptor, Receptors, Calcium-Sensing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72173b66555bd956618fe8850eb6bbd3
https://doi.org/10.1016/j.bmcl.2009.07.004

المؤلفون: Gayatri Balan, Paul S. Humphries, David Price, Liuqing Wei, David W. Piotrowski, Holly A. Simmons, James A. Southers, Yan Zhang, Mayda Castrodad, Vishwas M. Paralkar, Amit S. Kalgutkar, Jonathan N. Bauman, Y. Li, Constantin Neagu, Hong Qi, Mei Li, Sandra M. Jennings, Robert M. Oliver, Samit Kumar Bhattacharya, Michael Herr, Kimberly Lazarra, David R. Healy, Vishal Khot, Brendon Kapinos

المصدر: Bioorganic & Medicinal Chemistry Letters. 19:3328-3332

مصطلحات موضوعية: Cyclopropanes, Clinical Biochemistry, Rat model, Allosteric regulation, Administration, Oral, Pharmaceutical Science, Parathyroid hormone, Biochemistry, Anabolic Agents, Cell Line, Allosteric Regulation, Drug Discovery, Animals, Humans, Receptor, Molecular Biology, Phenylpropionates, Drug discovery, Chemistry, Organic Chemistry, Biological activity, Rats, Indans, Microsomes, Liver, Osteoporosis, Molecular Medicine, Calcium-sensing receptor, Receptors, Calcium-Sensing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d40d2c4c989804f739ac602f039d96
https://doi.org/10.1016/j.bmcl.2009.04.044

المؤلفون: Vishwas M. Paralkar, David D. Thompson, Iva Orlić, Lovorka Grgurevic, Dunja Rogić, Fran Borovečki, William A. Grasser, Petra Simic, Slobodan Vukicevic

المصدر: Kidney International. 70(6):1099-1106

مصطلحات موضوعية: Agonist, Nephrology, Male, medicine.medical_specialty, endocrine system, medicine.drug_class, Prostaglandin E2 receptor, Receptor expression, Renal function, Nephrectomy, Dinoprostone, chemistry.chemical_compound, Internal medicine, medicine, Animals, Receptors, Prostaglandin E, Rats, Wistar, prostaglandin E2, Creatinine, business.industry, urogenital system, ARF, Glomerulosclerosis, CRF, Acute Kidney Injury, Receptors, Prostaglandin E, EP2 Subtype, medicine.disease, EP2 receptor, EP4 receptor, Immunohistochemistry, Rats, Disease Models, Animal, Endocrinology, chemistry, Mercuric Chloride, Kidney Failure, Chronic, lipids (amino acids, peptides, and proteins), business, Receptors, Prostaglandin E, EP4 Subtype, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce9a02eea72ce7160487db51fabe541

المؤلفون: Bruce Allen Lefker, D.T. Crawford, Thomas A. Owen, Sandra Gilbert, Kimberly O. Cameron, Vishwas M. Paralkar, Shari L. DeNinno, Margaret Y. Chu-Moyer, Hua Zhu Ke, William A. Grasser, Christina M. Tjoa, Paul Da Silva Jardine, Dennis O. Scott, Bihong Lu, David D. Thompson, Hong Qi, Michael P. Zawistoski

المصدر: Bioorganic & Medicinal Chemistry Letters. 16:1799-1802

مصطلحات موضوعية: Agonist, Bone disease, Anabolism, medicine.drug_class, Ovariectomy, Clinical Biochemistry, Osteoporosis, Pharmaceutical Science, Pharmacology, Biochemistry, Bone and Bones, Rats, Sprague-Dawley, Bone Density, In vivo, Drug Discovery, medicine, Animals, Receptors, Prostaglandin E, Prostaglandin E2, Molecular Biology, Bone Development, Chemistry, Organic Chemistry, Organ Size, medicine.disease, In vitro, Rats, Ovariectomized rat, Molecular Medicine, Female, lipids (amino acids, peptides, and proteins), Receptors, Prostaglandin E, EP4 Subtype, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2bd36006c42a3f879ef0cc446622dd
https://doi.org/10.1016/j.bmcl.2006.01.018

المؤلفون: S.J. Dixon, H.Z. Ke, A.F. Weidema, William A. Grasser, C.A. Gabel, Hong Qi, D.T. Crawford, D.D. Thompson, Stephen M. Sims, M. Li, Vishwas M. Paralkar, L.P. Audoly, Webster S. S. Jee, Qian Zhang, Nattapon Panupinthu

المصدر: Molecular Endocrinology, 17, 7, pp. 1356-67
Molecular Endocrinology, 17, 1356-67

مصطلحات موضوعية: Male, medicine.medical_specialty, Patch-Clamp Techniques, Osteoporosis, Osteoclasts, Bone Marrow Cells, Biology, Bone resorption, Mice, Endocrinology, Osteoclast, Internal medicine, medicine, Animals, Femur, Bone Resorption, Receptor, Tomography, Molecular Biology, Cells, Cultured, Mice, Knockout, Bone Development, Osteoblasts, Receptors, Purinergic P2, Gene Expression Regulation, Developmental, General Medicine, medicine.disease, Resorption, Renal disorders [UMCN 5.4], Haematopoiesis, medicine.anatomical_structure, Female, Cortical bone, Receptors, Purinergic P2X7, Bone marrow

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f41ace89705b5136514de6991f559a
https://doi.org/10.1210/me.2003-0021