المؤلفون: Liqi He, Meng Yao Zhang, Matthew Cox, Qian Zhang, Andrew F. Donnell, Yong Zhang, Christine Tarby, Patrice Gill, Murugaiah A. M. Subbaiah, Thangeswaran Ramar, Maheswara Reddy, Vijaya Puttapaka, Yi-Xin Li, Prasanna Sivaprakasam, David Critton, Dawn Mulligan, Chunshan Xie, Radha Ramakrishnan, Jignesh Nagar, Shailesh Dudhgaonkar, Anwar Murtaza, Martins S. Oderinde, Gary L. Schieven, Arvind Mathur, Ashvinikumar V. Gavai, Gregory Vite, Sanjeev Gangwar, Yam B. Poudel

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Immunology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, synergistic antitumor activity, promising therapeutic agents, phenylpiperidine side chain, gathered considerable interest, novel tlr7 agonists, adme properties culminated, 14 , vivo <, like properties, 7 agonists, suggesting opportunities, pharmacodynamic profiles, oncology therapies, like receptor, favorable drug, demonstrated excellent, cancer immunotherapy, apd1 antibody, additional refinement

Relation: https://figshare.com/articles/journal_contribution/Identification_and_Optimization_of_Small_Molecule_Pyrazolopyrimidine_TLR7_Agonists_for_Applications_in_Immuno-oncology/24968292

الاتاحة: https://doi.org/10.1021/acsmedchemlett.3c00456.s001
https://figshare.com/articles/journal_contribution/Identification_and_Optimization_of_Small_Molecule_Pyrazolopyrimidine_TLR7_Agonists_for_Applications_in_Immuno-oncology/24968292