المؤلفون: Yan A. Ivanenkov, Alex Zhavoronkov, Renat S. Yamidanov, Ilya A. Osterman, Petr V. Sergiev, Vladimir A. Aladinskiy, Anastasia V. Aladinskaya, Victor A. Terentiev, Mark S. Veselov, Andrey A. Ayginin, Victor G. Kartsev, Dmitry A. Skvortsov, Alexey V. Chemeris, Alexey Kh. Baimiev, Alina A. Sofronova, Alexander S. Malyshev, Gleb I. Filkov, Dmitry S. Bezrukov, Bogdan A. Zagribelnyy, Evgeny O. Putin, Maria M. Puchinina, Olga A. Dontsova

المصدر: Frontiers in Pharmacology, Vol 10 (2019)

مصطلحات موضوعية: novel antibacterials, machine learning techniques, translation inhibitors, virtual screening, Kohonen-based SOM, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2019.00913/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/8c16a1d4d0ea467faf6fd76819573bdc

المؤلفون: Vladimir A. Aladinskiy, Rostislav A Petrov, Yan A. Ivanenkov, Mark S. Veselov, Andrey A Ayginin, Alexey Kh Baimiev, Maria M Puchinina, Marina A Maximova, Anastasia V. Aladinskaya, Dmitry A. Skvortsov, Kseniya Yu Shvetc, Yulia V. Vakhitova, Alina A. Sofronova, Ilya A. Osterman, Andrey Kh Baimiev, Zulfiya R Zileeva, Katerina S Komarova, Dmitry S. Bezrukov, L. F. Zainullina, Victor A Terentiev, Bogdan A Zagribelnyy, Petr V. Sergiev, Alexey E. Machulkin, Renat S. Yamidanov, Olga A. Dontsova

المصدر: Current Drug Discovery Technologies. 17:716-724

مصطلحات موضوعية: 0301 basic medicine, Staphylococcus aureus, medicine.drug_class, High-throughput screening, Antibiotics, Cephalosporin, Microbial Sensitivity Tests, Thiophenes, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Escherichia coli, medicine, biology, Chemistry, Broth microdilution, Antimicrobial, biology.organism_classification, Combinatorial chemistry, Small molecule, Anti-Bacterial Agents, High-Throughput Screening Assays, 030104 developmental biology, 030220 oncology & carcinogenesis, Antibacterial activity, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a9cc3c7142a75575f2c9fc022e9cc1
https://doi.org/10.2174/1570163816666190603095521

المؤلفون: Rostislav A Petrov, Dmitry A. Skvortsov, Yulia V. Vakhitova, L. F. Zainullina, Andrey A Ayginin, Yan A. Ivanenkov, Marina A Maximova, Mark S. Veselov, Alina A. Sofronova, Petr V. Sergiev, G. I. Filkov, Alexey E. Machulkin, Katerina S Komarova, Anastasia V. Aladinskaya, Renat S. Yamidanov, Victor A Terentiev, Olga A. Dontsova, Alexander S. Malyshev, Alexey Kh Baimiev, Maria M Puchinina, Ilya A. Osterman, Dmitry S. Bezrukov, A. V. Chemeris, Zulfiya R Zileeva, Vladimir A. Aladinskiy

المصدر: Combinatorial Chemistry & High Throughput Screening. 22:346-354

مصطلحات موضوعية: Chemistry, medicine.drug_class, Organic Chemistry, Antibiotics, Microbial Sensitivity Tests, General Medicine, Triazoles, Combinatorial chemistry, Anti-Bacterial Agents, Computer Science Applications, Mechanism of action, Protein Biosynthesis, Drug Discovery, Escherichia coli, medicine, Azetidines, Potency, Luciferase, medicine.symptom, Cytotoxicity, Antibacterial activity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336c3c036716b074c805801cbd19401f
https://doi.org/10.2174/1386207322666190412165316

المؤلفون: Andrey Baymiev, Rostislav A Petrov, Svetlana Iu Iarovenko, Vladimir A. Aladinskiy, Renat S. Yamidanov, Alexey E. Machulkin, Yan A. Ivanenkov, Mark S. Veselov, Katerina S Komarova, Olga A. Dontsova, Alexander S. Malyshev, Anastasia V. Aladinskaya, Victor A Terentiev, Andrey A Ayginin, Alina A. Sofronova, Petr V. Sergiev, Dmitry A. Skvortsov, Sergey V. Sadovnikov, Dmitrii A. Lukianov, Ilya A. Osterman, Dmitry S. Bezrukov, R.T. Matniyazov

المصدر: The Journal of Antibiotics. 72:827-833

مصطلحات موضوعية: 0301 basic medicine, Cell Survival, medicine.drug_class, 030106 microbiology, Antibiotics, Microbial Sensitivity Tests, medicine.disease_cause, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Minimum inhibitory concentration, Cell Line, Tumor, Drug Discovery, medicine, Humans, Potency, Cytotoxicity, Thiazole, Escherichia coli, Pharmacology, Molecular Structure, 010405 organic chemistry, Combinatorial chemistry, Anti-Bacterial Agents, High-Throughput Screening Assays, 0104 chemical sciences, Thiazoles, chemistry, Selectivity, Antibacterial activity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a36fba2b0d31d2a9e5211cc1d0ef53e
https://doi.org/10.1038/s41429-019-0211-y

المؤلفون: Yan A. Ivanenkov, Alex Zhavoronkov, Mark S. Veselov, Rim Shayakhmetov, Anastasiya V Aladinskaya, Daniil Polykovskiy, Victor A Terentiev, Vladimir A. Aladinskiy, Bogdan A Zagribelnyy, Tao Guo, Artem Zholus, Yury Volkov, Alexander Zhebrak, Lennart H Lee, Li Xing, Lidiya I Minaeva, Richard Soll, Alán Aspuru-Guzik, Alexander Aliper, David Madge, Maksim Kuznetsov, Arip Asadulaev

المصدر: Nature Biotechnology. 37:1038-1040

مصطلحات موضوعية: Models, Molecular, Cell signaling, Protein Conformation, Drug Evaluation, Preclinical, Biomedical Engineering, Bioengineering, Computational biology, Biology, Applied Microbiology and Biotechnology, Mice, Deep Learning, Dogs, Discoidin Domain Receptor 1, Animals, Humans, Enzyme Inhibitors, Receptor, DDR1, Molecular Structure, Kinase, Biological activity, Molecular Pharmacology, Rats, Generative model, Microsomes, Liver, Molecular Medicine, Discoidin domain, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57935a11c69db73ee57db030f1e4ba3b
https://doi.org/10.1038/s41587-019-0224-x

المؤلفون: A. A. Vladimirova, Ayrat R. Mavzyutov, Yan A. Ivanenkov, Kseniya Yu. Filyaeva, Victor G Kartsev, Valeriya I. Marina, Victor A Terentiev, Renat S. Yamidanov, Olga A. Dontsova, Andrey Baymiev, Julia V. Vakhitova, R.T. Matniyazov, Ilya A. Osterman, Dmitry S. Bezrukov, Alexey Kh. Baymiev, L. F. Zainullina, Zulfia R. Zileeva

المصدر: Bioorganic & Medicinal Chemistry Letters. 43:128055

مصطلحات موضوعية: Noscapine, Cell Survival, DNA damage, High-throughput screening, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, Gram-Positive Bacteria, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Gram-Negative Bacteria, Drug Discovery, medicine, Humans, Luciferase, Cytotoxicity, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, In vitro, Anti-Bacterial Agents, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, HEK293 Cells, Mechanism of action, Molecular Medicine, medicine.symptom, Antibacterial activity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec22722540a284b8ec7f0a235d6d3016
https://doi.org/10.1016/j.bmcl.2021.128055

المؤلفون: Rostislav A Petrov, Marina A Maximova, Yan A. Ivanenkov, Andrey A Ayginin, Zulfiya R Zileeva, Ilya A. Osterman, Dmitry S. Bezrukov, Alexey E. Machulkin, Katerina S Komarova, Victor A Terentiev, Mark S. Veselov, Vladimir A. Aladinskiy, Olga A. Dontsova, Anastasia V. Aladinskaya, Dmitry A. Skvortsov, Yulia V. Vakhitova, Renat S. Yamidanov, Alina A. Sofronova, Petr V. Sergiev, A. V. Chemeris, G. I. Filkov, Svetlana Yu. Maklakova, L. F. Zainullina, Victor G Kartsev, Alexey Kh Baimiev

المصدر: Molecular diversity. 24(1)

مصطلحات موضوعية: medicine.drug_class, Cell Survival, Pyridines, Antibiotics, Drug Evaluation, Preclinical, Microbial Sensitivity Tests, 010402 general chemistry, 01 natural sciences, Catalysis, Inorganic Chemistry, chemistry.chemical_compound, Structure-Activity Relationship, In vivo, Drug Discovery, Pyridine, medicine, Viability assay, Physical and Theoretical Chemistry, SOS response, Cytotoxicity, Molecular Biology, 010405 organic chemistry, Organic Chemistry, Indolizines, General Medicine, Combinatorial chemistry, 0104 chemical sciences, Anti-Bacterial Agents, High-Throughput Screening Assays, Mechanism of action, chemistry, medicine.symptom, Antibacterial activity, Information Systems

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59eba89cf136e9ae4cac5e8e9d33cda2
https://pubmed.ncbi.nlm.nih.gov/30949901

المؤلفون: Victor A Terentiev, Renat S. Yamidanov, Olga A. Dontsova, Mark S. Veselov, Alina A. Sofronova, Andrey A Ayginin, Anastasia V. Aladinskaya, Alexey E. Machulkin, Andrey Baymiev, Zulfiya R Zileeva, L. F. Zainullina, A. V. Chemeris, Rostislav A Petrov, Vladimir A. Aladinskiy, Dmitry A. Skvortsov, Marina A Maximova, Yulia V. Vakhitova, Maria M Puchinina, Petr V. Sergiev, Yan A. Ivanenkov, Alexey Kh. Baymiev, Ilya A. Osterman, Dmitry S. Bezrukov, Dmitrii A. Lukianov, Katerina S Komarova

المصدر: Combinatorial chemistryhigh throughput screening. 22(6)

مصطلحات موضوعية: Drug Evaluation, Preclinical, 03 medical and health sciences, chemistry.chemical_compound, Furanocoumarin, Structure-Activity Relationship, Furocoumarins, Drug Discovery, Protein biosynthesis, Escherichia coli, Humans, Luciferase, Cytotoxicity, Cells, Cultured, 030304 developmental biology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, 030306 microbiology, Drug discovery, Organic Chemistry, General Medicine, In vitro, Computer Science Applications, Anti-Bacterial Agents, High-Throughput Screening Assays, HEK293 Cells, Biochemistry, chemistry, A549 Cells, Protein Biosynthesis, MCF-7 Cells, Antibacterial activity, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea141cc0dae11e01a5cd8772c71eb80
https://pubmed.ncbi.nlm.nih.gov/31573876

المؤلفون: Yan A. Ivanenkov, Alex Zhavoronkov, Renat S. Yamidanov, Ilya A. Osterman, Petr V. Sergiev, Vladimir A. Aladinskiy, Anastasia V. Aladinskaya, Victor A. Terentiev, Mark S. Veselov, Andrey A. Ayginin, Victor G. Kartsev, Dmitry A. Skvortsov, Alexey V. Chemeris, Alexey Kh. Baimiev, Alina A. Sofronova, Alexander S. Malyshev, Gleb I. Filkov, Dmitry S. Bezrukov, Bogdan A. Zagribelnyy, Evgeny O. Putin, Maria M. Puchinina, Olga A. Dontsova

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, novel antibacterials, machine learning techniques, translation inhibitors, virtual screening, Kohonen-based SOM

Relation: https://figshare.com/articles/dataset/DataSheet_1_Identification_of_Novel_Antibacterials_Using_Machine_Learning_Techniques_pdf/9735533

الاتاحة: https://doi.org/10.3389/fphar.2019.00913.s001
https://figshare.com/articles/dataset/DataSheet_1_Identification_of_Novel_Antibacterials_Using_Machine_Learning_Techniques_pdf/9735533

المؤلفون: Yan A. Ivanenkov, Alex Zhavoronkov, Renat S. Yamidanov, Ilya A. Osterman, Petr V. Sergiev, Vladimir A. Aladinskiy, Anastasia V. Aladinskaya, Victor A. Terentiev, Mark S. Veselov, Andrey A. Ayginin, Victor G. Kartsev, Dmitry A. Skvortsov, Alexey V. Chemeris, Alexey Kh. Baimiev, Alina A. Sofronova, Alexander S. Malyshev, Gleb I. Filkov, Dmitry S. Bezrukov, Bogdan A. Zagribelnyy, Evgeny O. Putin, Maria M. Puchinina, Olga A. Dontsova

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, novel antibacterials, machine learning techniques, translation inhibitors, virtual screening, Kohonen-based SOM

Relation: https://figshare.com/articles/dataset/Table_7_Identification_of_Novel_Antibacterials_Using_Machine_Learning_Techniques_docx/9735566

الاتاحة: https://doi.org/10.3389/fphar.2019.00913.s012
https://figshare.com/articles/dataset/Table_7_Identification_of_Novel_Antibacterials_Using_Machine_Learning_Techniques_docx/9735566