يعرض 1 - 1 نتائج من 1 نتيجة بحث عن '"Vedwatee Gopaul"', وقت الاستعلام: 0.31s تنقيح النتائج
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    Overcoming the Genotoxicity of a Pyrrolidine Substituted Arylindenopyrimidine As a Potent Dual Adenosine A2A/A1 Antagonist by Minimizing Bioactivation to an Iminium Ion Reactive Intermediate

    المؤلفون: Jose Silva, Heng-Keang Lim, Vedwatee Gopaul, Tynisha Thomas, Rhys Salter, Paul F. Jackson, Kevin Cook, Kenneth J. Rhodes, Carlo Sensenhauser, Stefanie Rassnick, David C. Evans, Chen Jie, Robert Preston, Brian C. Shook

    المصدر: Chemical Research in Toxicology. 24:1012-1030

    مصطلحات موضوعية: Salmonella typhimurium, Pyrrolidines, Receptor, Adenosine A2A, Stereochemistry, Metabolite, Reactive intermediate, Mutagen, Adenosine A1 Receptor Antagonists, Toxicology, medicine.disease_cause, Adenosine receptor antagonist, Mass Spectrometry, Pyrrolidine, DNA Adducts, Mice, chemistry.chemical_compound, medicine, Animals, Humans, Biotransformation, Chromatography, High Pressure Liquid, Ions, Mutagenicity Tests, Receptor, Adenosine A1, Chemistry, Iminium, DNA, General Medicine, Adenosine A2 Receptor Antagonists, Rats, Pyrimidines, Indenes, Imines, Genotoxicity

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e7471f9a767bbd6ed26775c7fa579a
    https://doi.org/10.1021/tx1004437

    View record in OpenAIRE

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