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1Academic Journal
المؤلفون: Kathrin Leppek, Gun Woo Byeon, Wipapat Kladwang, Hannah K. Wayment-Steele, Craig H. Kerr, Adele F. Xu, Do Soon Kim, Ved V. Topkar, Christian Choe, Daphna Rothschild, Gerald C. Tiu, Roger Wellington-Oguri, Kotaro Fujii, Eesha Sharma, Andrew M. Watkins, John J. Nicol, Jonathan Romano, Bojan Tunguz, Fernando Diaz, Hui Cai, Pengbo Guo, Jiewei Wu, Fanyu Meng, Shuai Shi, Eterna Participants, Philip R. Dormitzer, Alicia Solórzano, Maria Barna, Rhiju Das
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2
المؤلفون: Wipapat Kladwang, Ramya Rangan, Ivan N Zheludev, Wah Chiu, Andrew M. Watkins, Zhaoming Su, Ved V Topkar, Kaiming Zhang, Rhiju Das, Shanshan Li, Joseph D. Yesselman, Kalli Kappel, Grigore D. Pintilie
المصدر: Nature methods
مصطلحات موضوعية: Models, Molecular, Riboswitch, Cryo-electron microscopy, Aptamer, Mutagenesis (molecular biology technique), Computational biology, Biochemistry, Article, 03 medical and health sciences, Computer Simulation, RNA, Catalytic, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, DNA ligase, biology, Chemistry, Cryoelectron Microscopy, Tetrahymena, Ribozyme, RNA, Cell Biology, biology.organism_classification, MicroRNAs, biology.protein, Nucleic Acid Conformation, Biotechnology
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3
المؤلفون: Sarah C. Keane, Wipapat Kladwang, Bei Liu, Ved V Topkar, Tracy L. Hodges, Ramya Rangan, Hashim M. Al-Hashimi, Rhiju Das
المصدر: Biochemistry
مصطلحات موضوعية: Untranslated region, chemistry.chemical_classification, 0303 health sciences, Messenger RNA, Adenosine, Magnetic Resonance Spectroscopy, Polyadenylation, Polymers, Chemistry, 030302 biochemistry & molecular biology, Electrophoresis, Capillary, RNA, Chemical modification, Reverse Transcription, Biochemistry, Article, Reverse transcriptase, 03 medical and health sciences, Biophysics, Nucleotide, Nucleic acid structure
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4
المؤلفون: Kathrin Leppek, Gun Woo Byeon, Wipapat Kladwang, Hannah K. Wayment-Steele, Craig H. Kerr, Adele F. Xu, Do Soon Kim, Ved V. Topkar, Christian Choe, Daphna Rothschild, Gerald C. Tiu, Roger Wellington-Oguri, Kotaro Fujii, Eesha Sharma, Andrew M. Watkins, John J. Nicol, Jonathan Romano, Bojan Tunguz, Fernando Diaz, Hui Cai, Pengbo Guo, Jiewei Wu, Fanyu Meng, Shuai Shi, Eterna Participants, Philip R. Dormitzer, Alicia Solórzano, Maria Barna, Rhiju Das
المصدر: bioRxiv
article-version (status) pre
article-version (number) 1مصطلحات موضوعية: mRNA translation, RNA Stability, Stability (learning theory), General Physics and Astronomy, Computational biology, polysome profiling, Ribosome, General Biochemistry, Genetics and Molecular Biology, Article, Pseudouridine, chemistry.chemical_compound, vaccine, Humans, RNA, Messenger, RNA structure, Eterna, Messenger RNA, Multidisciplinary, Chemistry, COVID-19, RNA, Translation (biology), General Chemistry, CDS sequence variants, in-line RNA structure probing, MRNA Instability, Combinatorial optimization
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5
المؤلفون: Ved V Topkar, Meng-meng Fu, Lindsey Madsen Meservey
المصدر: Trends Cell Biol
Trends in cell biology, vol 31, iss 6مصطلحات موضوعية: 1.1 Normal biological development and functioning, Messenger, Biology, Medical and Health Sciences, Article, 03 medical and health sciences, 0302 clinical medicine, Underpinning research, Genetics, medicine, MRNA transport, RNA, Messenger, 030304 developmental biology, Neurons, 0303 health sciences, Microglia, Neurosciences, Translation (biology), Cell Biology, Biological Sciences, Cell biology, Oligodendroglia, medicine.anatomical_structure, nervous system, Astrocytes, Neurological, RNA, Neuroglia, 030217 neurology & neurosurgery, Intracellular, Developmental Biology
وصف الملف: application/pdf
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6
المؤلفون: Shengdar Q. Tsai, Jose Malagon-Lopez, Martin J. Aryee, Ved V Topkar, Nhu T. Nguyen, J. Keith Joung
المصدر: Nature methods
مصطلحات موضوعية: 0301 basic medicine, Sequence analysis, Sensitivity and Specificity, Biochemistry, Genome, Article, Off targets, 03 medical and health sciences, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Molecular Biology, Genetics, Nuclease, Deoxyribonucleases, biology, Chromosome Mapping, High-Throughput Nucleotide Sequencing, Reproducibility of Results, Sequence Analysis, DNA, Cell Biology, In vitro, Highly sensitive, 030104 developmental biology, biology.protein, CRISPR-Cas Systems, Biotechnology, Reference genome
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7
المؤلفون: Andrew M. Watkins, Wipapat Kladwang, Shanshan Li, Wah Chiu, Ramya Rangan, Joseph D. Yesselman, Ivan N Zheludev, Zhaoming Su, Rhiju Das, Kaiming Zhang, Kalli Kappel, Ved V Topkar, Grigore D. Pintilie
مصطلحات موضوعية: Riboswitch, chemistry.chemical_classification, 0303 health sciences, DNA ligase, biology, Chemistry, Aptamer, Ribozyme, Tetrahymena, Mutagenesis (molecular biology technique), RNA, Computational biology, biology.organism_classification, 03 medical and health sciences, 0302 clinical medicine, biology.protein, 030217 neurology & neurosurgery, 030304 developmental biology
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8
المؤلفون: Shengdar Q. Tsai, Benjamin P. Kleinstiver, Zongli Zheng, J. Keith Joung, Michelle S. Prew, Ved V Topkar, Nhu T. Nguyen
المصدر: Nature Biotechnology. 33:1293-1298
مصطلحات موضوعية: Genetics, Cas9, Biomedical Engineering, Bioengineering, Biology, medicine.disease_cause, Applied Microbiology and Biotechnology, DNA sequencing, Protospacer adjacent motif, Genome editing, Molecular evolution, Staphylococcus aureus, parasitic diseases, medicine, Molecular Medicine, CRISPR, Guide RNA, Biotechnology
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9
المؤلفون: Benjamin P. Kleinstiver, Michelle S. Prew, Shengdar Q. Tsai, Ved V. Topkar, Nhu T. Nguyen, Zongli Zheng, Andrew P. W. Gonzales, Zhuyun Li, Randall T. Peterson, Jing-Ruey Joanna Yeh, Martin J. Aryee, J. Keith Joung
المصدر: Nature
مصطلحات موضوعية: Staphylococcus aureus, Streptococcus pyogenes, CRISPR-Associated Proteins, Computational biology, Biology, Protein Engineering, medicine.disease_cause, Genome, Article, Cell Line, Substrate Specificity, Molecular engineering, stomatognathic system, parasitic diseases, medicine, Animals, Humans, Streptococcus thermophilus, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Nucleotide Motifs, Zebrafish, Epigenomics, Genetics, Mutation, Multidisciplinary, Protein engineering, Protospacer adjacent motif, Genomic engineering, Amino Acid Substitution, CRISPR-Cas Systems, Directed Molecular Evolution
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10
المصدر: Journal of the American Chemical Society
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Base pair, Thiouridine, Sequence (biology), 010402 general chemistry, 01 natural sciences, Biochemistry, Catalysis, Primer extension, Article, 03 medical and health sciences, chemistry.chemical_compound, Colloid and Surface Chemistry, 030304 developmental biology, 0303 health sciences, Chemistry, Oligonucleotide, RNA, General Chemistry, Uridine, 0104 chemical sciences, Kinetics, Template, Nucleic Acid Conformation
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11
المصدر: PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0186324 (2017)مصطلحات موضوعية: 0301 basic medicine, lcsh:Medicine, Gene Expression, Computational biology, Biology, ENCODE, Biochemistry, Cell Line, Epigenesis, Genetic, 03 medical and health sciences, DNA-binding proteins, Genetics, Nucleosome, Histone code, Humans, Gene Regulation, Epigenetics, Gene Silencing, lcsh:Science, Non-coding RNA, Epigenomics, Multidisciplinary, DNA methylation, Chromosome Biology, Chromatin Modification, lcsh:R, Biology and Life Sciences, Proteins, Histone Modification, Cell Biology, DNA, Models, Theoretical, Chromatin, Regulatory Proteins, Nucleic acids, Histone Code, 030104 developmental biology, Histone, Genetic Loci, biology.protein, Long non-coding RNAs, RNA, lcsh:Q, DNA modification, Research Article, Transcription Factors
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12
المؤلفون: Ved V Topkar
المصدر: Biophysical Journal. 118:67a
مصطلحات موضوعية: Chemistry, Biophysics, MRNA transport, Cell biology
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13
المؤلفون: Martin J. Aryee, Matthew Liebers, Ved V Topkar, Cyd Khayter, Shengdar Q. Tsai, Long P. Le, Nhu T. Nguyen, Vishal Thapar, A. John Iafrate, Zongli Zheng, Nicolas Wyvekens, J. Keith Joung
المصدر: Nature biotechnology
مصطلحات موضوعية: Genetics, 0303 health sciences, Targeted Gene Repair, genetic processes, Biomedical Engineering, Bioengineering, Biology, Applied Microbiology and Biotechnology, Genome, Article, 03 medical and health sciences, Protospacer adjacent motif, chemistry.chemical_compound, 0302 clinical medicine, chemistry, RNA editing, Molecular Medicine, CRISPR, Human genome, Guide RNA, 030217 neurology & neurosurgery, DNA, 030304 developmental biology, Biotechnology
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14
المؤلفون: J. Keith Joung, Nhu T. Nguyen, Shengdar Q. Tsai, Jose Malagon-Lopez, Martin J. Aryee, Ved V Topkar
المصدر: Nature Methods. 15:394-394
مصطلحات موضوعية: 0301 basic medicine, Nuclease, biology, Cell Biology, Computational biology, Biochemistry, Genome, In vitro, Highly sensitive, Off targets, 03 medical and health sciences, 030104 developmental biology, Nat, biology.protein, CRISPR, Molecular Biology, Biotechnology
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15
المؤلفون: Ved V Topkar, J. Keith Joung, Martin J. Aryee, Shengdar Q. Tsai
المصدر: Nature Biotechnology. 34:483-483
مصطلحات موضوعية: 0301 basic medicine, Computer science, Biomedical Engineering, Bioengineering, computer.software_genre, Applied Microbiology and Biotechnology, Access to Information, 03 medical and health sciences, Software analytics, Clustered Regularly Interspaced Short Palindromic Repeats, Software system, Software verification and validation, Software measurement, Internet, Database, business.industry, Software development, High-Throughput Nucleotide Sequencing, Sequence Analysis, DNA, Software quality, 030104 developmental biology, Software construction, Molecular Medicine, Programming Languages, Backporting, business, computer, Algorithms, Software, Biotechnology
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16
المؤلفون: Shengdar Q. Tsai, Michelle S. Prew, Ved V Topkar, Benjamin P. Kleinstiver, Jae Keith Joung
المصدر: Molecular Therapy. 23:S26
مصطلحات موضوعية: Pharmacology, Genetics, Nuclease, biology, Cas9, Heterologous, medicine.disease_cause, Genome, Protospacer adjacent motif, Drug Discovery, Streptococcus pyogenes, biology.protein, medicine, Molecular Medicine, CRISPR, Molecular Biology, Gene
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17
المؤلفون: Zongli Zheng, Ved V Topkar, Cyd Khayter, Nhu T. Nguyen, Vishal Thapar, Nicolas Wyvekens, Matthew Liebers, Shengdar Q. Tsai
المصدر: Molecular Therapy. 23:S274
مصطلحات موضوعية: Pharmacology, Genetics, Palindrome, RNA, Biology, Human cell, Cleavage (embryo), Genome, Genome editing, Target site, Drug Discovery, Molecular Medicine, CRISPR, Molecular Biology
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