يعرض 1 - 8 نتائج من 8 نتيجة بحث عن '"Vasilios Marathias"', وقت الاستعلام: 0.37s تنقيح النتائج
  1. 1
    First Scale-Up Synthesis of WAY-262398, a Novel, Dual-Acting SSRI/5HT1a Antagonist

    المؤلفون: Asaf Alimardanov, Nicole T. Hatzenbuhler, Steve Lenicek, Livia Kristofova, Deborah Ann Evrard, Afragola Jay Thomas, Antonia Nikitenko, Gary Paul Stack, Jean Schmid, Vasilios Marathias, John R. Potoski

    المصدر: Organic Process Research & Development. 13:91-97

    مصطلحات موضوعية: Preparative hplc, Stereochemistry, Chemistry, Organic Chemistry, SCALE-UP, Antagonist, Diastereomer, Physical and Theoretical Chemistry, Enantiomeric excess, Combinatorial chemistry, Chiral resolution

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::188865e104ad8fb99427553d8d459b42
    https://doi.org/10.1021/op8002085

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  2. 2
    Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery—Building chiral technology toolboxes

    المؤلفون: Li Di, Leonard A. McDonald, Mairead Young, Lisa Nogle, Dahui Zhou, Brian L. Marquez, Mei-Yi Zhang, William L. Watts, Frank E. Koehn, Alvin C. Bach, Yanxuan Cai, Alan G. Sutherland, Neal Byrne, Guy T. Carter, Michael Z. Kagan, Edward H. Kerns, Mark Tischler, Carl J. Balibar, Oliver J. McConnell, Igor Goljer, Gerhard Schlingmann, Yanan He, Don Herold, Douglas M. Ho, Michael Chlenov, Christopher J. Petucci, R. Thomas Williamson, Gregory J. Tawa, Yingru Zhang, Vasilios Marathias, Christina M. Kraml, Kristi Fan

    المصدر: Chirality. 19:658-682

    مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Drug Industry, Stereochemistry, Chemistry, Pharmaceutical, Molecular Conformation, Electrons, Catalysis, Analytical Chemistry, Prochirality, Drug Discovery, Humans, Technology, Pharmaceutical, Optical rotation, Chiral derivatizing agent, Spectroscopy, Pharmacology, Chromatography, Drug discovery, Chemistry, Circular Dichroism, Organic Chemistry, Absolute configuration, Enantioselective synthesis, Stereoisomerism, Models, Chemical, Drug Design, Supercritical fluid chromatography, Salts, Enantiomer

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76974c7b396b4bbc3b5ccb44e18646ca
    https://doi.org/10.1002/chir.20399

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  3. 3
    Simultaneous determination of1H-1H and1H-13C residual dipolar couplings in a chiral liquid crystal solvent using a natural abundance HSQC experiment

    المؤلفون: Vasilios Marathias, Alvin C. Bach, Igor Goljer

    المصدر: Magnetic Resonance in Chemistry. 43:512-519

    مصطلحات موضوعية: Carbon Isotopes, Crystallography, Magnetic Resonance Spectroscopy, Chemistry, Microchemistry, Analytical chemistry, Stereoisomerism, General Chemistry, Carbon-13 NMR, Solvent, Residual dipolar coupling, Liquid crystal, Solvents, Proton NMR, General Materials Science, Transverse relaxation-optimized spectroscopy, Protons, Solubility, Peptides, Heteronuclear single quantum coherence spectroscopy

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873a72df049b1a1a2b5d2d16d0db7e3c
    https://doi.org/10.1002/mrc.1597

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  4. 4
    Substituent effects on 13C NMR chemical shifts in dialkylaminophenylchlorophosphines

    المؤلفون: Brian P. Coppola, Vasilios Marathias, Mark M. Turnbull, Robert L. Ii. Abdon

    المصدر: Polyhedron. 11:2759-2766

    مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Chemical shift, Substituent, Nuclear magnetic resonance spectroscopy, Carbon-13 NMR, Resonance (chemistry), Spectral line, Inorganic Chemistry, chemistry.chemical_compound, Crystallography, chemistry, Materials Chemistry, Amine gas treating, Physical and Theoretical Chemistry, Alkyl

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::83bcdf9da4c66d373532e5e4a00b7688
    https://doi.org/10.1016/s0277-5387(00)83633-5

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  5. 5
    Stereochemical identification of (R)- and (S)-ibuprofen using residual dipolar couplings, NMR, and modeling

    المؤلفون: Gregory J. Tawa, Igor Goljer, Vasilios Marathias, Alvin C. Bach

    المصدر: Chirality. 19(9)

    مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Stereochemistry, Chemistry, Pharmaceutical, Chemistry, Organic, Molecular Conformation, Stereoisomerism, Ibuprofen, Crystal structure, Catalysis, Analytical Chemistry, Liquid crystal, Drug Discovery, Molecule, Technology, Pharmaceutical, Conformational isomerism, Spectroscopy, Pharmacology, Molecular Structure, Chemistry, Organic Chemistry, Models, Theoretical, Crystallography, Models, Chemical, Reagent, Solvents, Enantiomer, Crystallization, Magnetic dipole–dipole interaction

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428d685af9c4904c90c7c9add6b47095
    https://pubmed.ncbi.nlm.nih.gov/17094072

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  6. 6
    A convenient, reproducible two-step synthesis of 6,6-dimethylbicyclo[3.1.1]heptane-2,4-dione

    المؤلفون: Jerome C. Wu, Wayne E. Childers, Vasilios Marathias

    المصدر: Tetrahedron Letters. 47:2217-2218

    مصطلحات موضوعية: chemistry.chemical_classification, Heptane, chemistry.chemical_compound, Ozonolysis, Double bond, chemistry, Product (mathematics), Yield (chemistry), Organic Chemistry, Drug Discovery, Two step, Organic chemistry, Biochemistry

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::677b49dcebd39fb18a23a935b55301ab
    https://doi.org/10.1016/j.tetlet.2006.01.102

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  7. 7
    Academic Journal
    First Scale-Up Synthesis of WAY-262398, a Novel, Dual-Acting SSRI/5HT1a Antagonist.

    المؤلفون: Antonia Nikitenko, Asaf Alimardanov, Jay Afragola, Jean Schmid, Livia Kristofova, Deborah Evrard, Nicole T. Hatzenbuhler, Vasilios Marathias, Gary Stack, Steve Lenicek, John Potoski

    المصدر: Organic Process Research & Development; Jan2009, Vol. 13 Issue 1, p91-97, 7p


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  8. 8
    Academic Journal
    Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery—Building chiral technology toolboxesIn contrast to previous usage, Chiral Technology is defined in this review as the use of techniques or tools for the determination of absolute stereochemistry, the chiral analysis or preparative separation of racemic small molecules containing one or more asymmetric centers into (all of) their enantiomers (= enantiomeric or chiral separation), and the facilitation of asymmetric transformations, but not asymmetric transformations themselves. The terms Chiral Technology and Chirotechnology have often been used as a general category for asymmetric transformations using enzymes, chiral building blocks, chiral auxiliaries, and chiral catalysts, as well as chiral salt resolution.1–13

    المؤلفون: Oliver McConnell, Alvin Bach, Carl Balibar, Neal Byrne, Yanxuan Cai, Guy Carter, Michael Chlenov, Li Di, Kristi Fan, Igor Goljer, Yanan He, Don Herold, Michael Kagan, Edward Kerns, Frank Koehn, Christina Kraml, Vasilios Marathias, Brian Marquez, Leonard McDonald, Lisa Nogle

    المصدر: Chirality; Sep2007, Vol. 19 Issue 9, p658-682, 25p


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