المؤلفون: Jéssika de Oliveira Viana, Mayara Barbalho Félix, Mayara dos Santos Maia, Vanessa de Lima Serafim, Luciana Scotti, Marcus Tullius Scotti

المصدر: Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss spe (2018)

مصطلحات موضوعية: Drug design, Multitarget compounds, In silico, Diseases, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000700409&lng=en&tlng=en; https://doaj.org/toc/2175-9790

URL الوصول: https://doaj.org/article/e5ed8b0ffbe246788c7302e7ba46c9c5

المؤلفون: Francisco Jaime Bezerra Mendonça-Junior, Ricardo Olímpio de Moura, Edeildo Ferreira da Silva-Júnior, João Xavier de Araújo-Júnior, Karin Y. Chumbimuni-Torres, Stephanie M. Armas, Thiago Mendoça de Aquino, Vanessa de Lima Serafim, Katherine Lozano Untiveros, Emanuella Gomes da Silva, Fabiane C. de Abreu

المصدر: Biosensors and Bioelectronics. 133:160-168

مصطلحات موضوعية: DNA, Complementary, Ultraviolet Rays, DNA damage, Guanine, Intercalation (chemistry), Biomedical Engineering, Biophysics, Antineoplastic Agents, Biosensing Techniques, 02 engineering and technology, 01 natural sciences, chemistry.chemical_compound, Complementary DNA, Electrochemistry, Humans, Chemistry, Inverted Repeat Sequences, 010401 analytical chemistry, DNA, Electrochemical Techniques, General Medicine, 021001 nanoscience & nanotechnology, Combinatorial chemistry, Intercalating Agents, 0104 chemical sciences, Molecular Docking Simulation, Nucleic acid, Gold, Differential pulse voltammetry, 0210 nano-technology, Oxidation-Reduction, Biosensor, DNA Damage, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26943811574a94283c51bfba98a8ecc6
https://doi.org/10.1016/j.bios.2019.02.071

المؤلفون: Maria Dayanne de A. Dantas, Eduarda de O. O. Nascimento, Thiago Mendonça de Aquino, Ricardo Olímpio de Moura, Helena Mariana Pitangueira Teixeira, Ana Ligia da Costa Pereira, Milena Botelho Pereira Soares, Vanessa de Lima Serafim, Francisco Jaime Bezerra Mendonça-Junior, Marina de Magalhães Silva, Taís S. Macedo, Thamilla Maria S. Maciel, Josué Carinhanha Caldas Santos, Isis M. Figueiredo, João Xavier de Araújo-Júnior, Maria do Carmo Alves de Lima, Diogo Rodrigo Magalhães Moreira, Edeildo Ferreira da Silva-Júnior

المصدر: Journal of Photochemistry and Photobiology B: Biology. 189:165-175

مصطلحات موضوعية: Intercalation (chemistry), Biophysics, Supramolecular chemistry, Serum Albumin, Human, 010402 general chemistry, 01 natural sciences, Antimalarials, Structure-Activity Relationship, chemistry.chemical_compound, medicine, Humans, Radiology, Nuclear Medicine and imaging, Amsacrine, Binding Sites, Radiation, Radiological and Ultrasound Technology, 010405 organic chemistry, Biological activity, DNA, Combinatorial chemistry, Intercalating Agents, 0104 chemical sciences, Mechanism of action, chemistry, Biological target, Acridine, Acridines, medicine.symptom, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a390964902d2acfc5f241f72c45234
https://doi.org/10.1016/j.jphotobiol.2018.10.016

المؤلفون: Vivianne Mendes Mangueira, Monalisa Taveira Brito, Renata Albuquerque de Abrantes, Tatyanna Kelvia Gomes de Sousa, Vanessa de Lima Serafim, Robson Cavalcanti Veras, Ana Ligia da Costa Pereira, Tatianne Mota Batista, Isac Almeida de Medeiros, Marianna Vieira Sobral, Ricardo Olímpio de Moura, Ryldene Marques Duarte da Cruz, Karina Karla de Paula Medeiros

المصدر: Biomedicine & Pharmacotherapy. 90:253-261

مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Angiogenesis Inhibitors, Antineoplastic Agents, Apoptosis, Pharmacology, medicine.disease_cause, Ehrlich ascites carcinoma, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Animals, Viability assay, Carcinoma, Ehrlich Tumor, Amsacrine, Cell Proliferation, Chemistry, Cell Cycle, Ascites, Cell Cycle Checkpoints, General Medicine, Acute toxicity, 030104 developmental biology, 030220 oncology & carcinogenesis, Immunology, Toxicity, Acridines, Female, Micronucleus, Genotoxicity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf480acf91d16153a66e6a9ad2901c44
https://doi.org/10.1016/j.biopha.2017.03.049

المؤلفون: Willams Leal Silva, Vanessa de Lima Serafim, Elizabeth Almeida Lafayette, Luiz Bezerra de Carvalho Júnior, Jorge L. Neves, Ana Lúcia Tasca Gois Ruiz, Sinara Mônica Vitalino de Almeida, Thaís Meira Menezes, Ricardo Olímpio de Moura, Eduardo Isidoro Carneiro Beltrão, João Carvalho, Maria do Carmo Alves de Lima

المصدر: International Journal of Biological Macromolecules. 92:467-475

مصطلحات موضوعية: Topoisomerase Inhibitors, medicine.drug_class, Stereochemistry, Proton Magnetic Resonance Spectroscopy, Substituent, 010402 general chemistry, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Structural Biology, Cell Line, Tumor, medicine, Animals, Humans, Spiro Compounds, Carbon-13 Magnetic Resonance Spectroscopy, Molecular Biology, Amsacrine, Cell Proliferation, biology, 010405 organic chemistry, Cell growth, Topoisomerase, DNA, General Medicine, Binding constant, 0104 chemical sciences, Spectrometry, Fluorescence, chemistry, Acridine, biology.protein, Acridines, Cattle, Spectrophotometry, Ultraviolet, DNA Topoisomerases, Topoisomerase inhibitor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b050d69fc5cb47d7098cdc8efc72beff
https://doi.org/10.1016/j.ijbiomac.2016.07.057

المؤلفون: Tatianne Mota Batista, Marianna Vieira Sobral, Vanessa de Lima Serafim, Daiana Karla Frade Silva, Márcia Rosa de Oliveira, Vivianne Mendes Mangueira, Wagner Luis Tafuri, Patrícia Néris Andrade, Ricardo Olímpio de Moura, Francisco Jaime Bezerra Mendonça Junior, Adriano Francisco Alves, Klinger Antonio da Franca Rodrigues

المصدر: Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 108

مصطلحات موضوعية: 0301 basic medicine, 030231 tropical medicine, Antiprotozoal Agents, Administration, Oral, Biological Availability, Spleen, Thiophenes, Pharmacology, medicine.disease_cause, Median lethal dose, Parasite Load, 03 medical and health sciences, Interferon-gamma, Mice, 0302 clinical medicine, In vivo, medicine, Toxicity Tests, Acute, Animals, Parasites, Leishmaniasis, Leishmania, business.industry, Weight change, General Medicine, medicine.disease, Acute toxicity, Interleukin-10, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Micronucleus test, Cytokines, Female, business, Genotoxicity, Mutagens

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec814117e377e69db265148e2630055
https://pubmed.ncbi.nlm.nih.gov/30372869

المؤلفون: Vanessa de Lima Serafim, Luciana Scotti, Marcus Scotti

المصدر: Proceedings of MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd edition.

مصطلحات موضوعية: Chemistry, Growth factor, medicine.medical_treatment, In silico, Cancer research, medicine, Receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b7862b61173c462a09a01ad5c27facad
https://doi.org/10.3390/mol2net-03-05065

المؤلفون: Ricardo Olímpio de Moura, Klinger Antonio da Franca Rodrigues, Patrícia Néris Andrade, Maria do Carmo Alves de Lima, Mayara Barbalho Félix, Márcia Rosa de Oliveira, Daiana Karla Frade Silva, Sinara Mônica Vitalino de Almeida, Jamerson Ferreira de Oliveira, Marcus Tullius Scotti, Francisco Jaime Bezerra Mendonça-Junior, Sanderssonilo de Albuquerque dos Santos, Vanessa de Lima Serafim

المصدر: Chemical biologydrug design. 91(6)

مصطلحات موضوعية: 0301 basic medicine, Erythrocytes, Stereochemistry, Leishmania mexicana, Pyruvate Kinase, Antiprotozoal Agents, Drug Resistance, Protozoan Proteins, Thiophenes, 01 natural sciences, Biochemistry, Hemolysis, 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, Catalytic Domain, Drug Discovery, Thiophene, Humans, Fragmentation (cell biology), Least-Squares Analysis, Pharmacology, Binding Sites, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Active site, DNA, Protozoan, Binding constant, 0104 chemical sciences, Molecular Docking Simulation, 030104 developmental biology, Lipophilicity, Acridine, biology.protein, Molecular Medicine, DNA fragmentation, Acridines, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb989b5dd11005776f964d575cedf59
https://pubmed.ncbi.nlm.nih.gov/29415325

المؤلفون: Daiana Karla G. Frade, Mayara Barbalho Félix, Marcus Tullius Scotti, Luciana Scotti, Vanessa de Lima Serafim, Francisco Jaime Bezerra Mendonça Junior, Márcia Rosa de Oliveira, Thiago Mendonça de Aquino, Maria do Carmo Alves de Lima, Frederico Fávaro Ribeiro, Klinger Antonio da Franca Rodrigues, Patrícia Lima do Nascimento Néris, Edson Rubhens de Souza

المصدر: Bioorganicmedicinal chemistry. 24(18)

مصطلحات موضوعية: Indoles, Stereochemistry, Clinical Biochemistry, Leishmania mexicana, Antiprotozoal Agents, Pharmaceutical Science, Leishmaniasis, Cutaneous, DNA Fragmentation, Thiophenes, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, Drug Discovery, Thiophene, Structure–activity relationship, Humans, Cytotoxicity, Molecular Biology, IC50, Indole test, biology, 010405 organic chemistry, Organic Chemistry, biology.organism_classification, Combinatorial chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Lipophilicity, Molecular Medicine, DNA fragmentation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d98bec143dc4130519c0a2437a7a53
https://pubmed.ncbi.nlm.nih.gov/27515718