المؤلفون: Goulooze, Sebastian C., Voller, Swantje, Valitalo, Pyry AJ, Calvier, Elisa AM, Aarons, Leon, Krekels, Elke HJ, Knibbe, Catherijne A.J.

المصدر: Goulooze , S C , Voller , S , Valitalo , P AJ , Calvier , E AM , Aarons , L , Krekels , E HJ & Knibbe , C A J 2018 , ' The Influence of Normalization Weight in Population Pharmacokinetic Covariate Models ' , Clinical Pharmacokinetics . https://doi.org/10.1007/s40262-018-0652-7

الاتاحة: https://research.manchester.ac.uk/en/publications/0d1cde9e-0541-44b0-ac2d-5256ba985800
https://doi.org/10.1007/s40262-018-0652-7

المؤلفون: Calvier, Elisa AM, Krekels, Elke HJ, Yu, Huixin, Valitalo, Pyry AJ, Johnson, Trevor N, Rostami-Hodjegan, Amin, Tibboel, Dick, van der Graaf, Piet H, Danhof, Meindert, Knibbe, Catherijne AJ

المصدر: Calvier , E AM , Krekels , E HJ , Yu , H , Valitalo , P AJ , Johnson , T N , Rostami-Hodjegan , A , Tibboel , D , van der Graaf , P H , Danhof , M & Knibbe , C AJ 2018 , ' Drugs Being Eliminated via the Same Pathway Will Not Always Require Similar Pediatric Dose Adjustments ' , CPT: Pharmacometrics and Systems Pharmacology , vol. 7 , no. 3 , PSP412273 , pp. 175-185 . https://doi.org/10.1002/psp4.12273

الاتاحة: https://research.manchester.ac.uk/en/publications/833ce673-1d1f-459e-91d9-39fffcd76cba
https://doi.org/10.1002/psp4.12273
http://www.scopus.com/inward/record.url?scp=85041314380&partnerID=8YFLogxK

المؤلفون: Valitalo, Pyry, Kokki, Merja, Ranta, Veli-Pekka, Olkkola, Klaus T., Hooker, Andrew C., Kokki, Hannu

المساهمون: Clinicum, Anestesiologian yksikkö, Department of Diagnostics and Therapeutics, HUS Perioperative, Intensive Care and Pain Medicine

مصطلحات موضوعية: analgesic, opioid. infant, extremely premature, oxycodone, pain, pharmacokinetics, DEVELOPMENTAL PHARMACOKINETICS, CHILDREN, METABOLITES, MORPHINE, Chemical sciences, Pharmacy

وصف الملف: application/pdf

Relation: This study was funded by a governmental research grant number 507A002 from the Hospital District of Northern Savo, Kuopio, Finland. The authors thank professor Catherijne A.J. Knibbe for her critical comments during the preparation of the manuscript.; Valitalo , P , Kokki , M , Ranta , V-P , Olkkola , K T , Hooker , A C & Kokki , H 2017 , ' Maturation of Oxycodone Pharmacokinetics in Neonates and Infants : a Population Pharmacokinetic Model of Three Clinical Trials ' , Pharmaceutical Research , vol. 34 , no. 5 , pp. 1125-1133 . https://doi.org/10.1007/s11095-017-2122-6; ORCID: /0000-0001-7872-8665/work/32700817; http://hdl.handle.net/10138/234743; 6336c356-f931-4c61-9829-f048b5d284b6; 85012891079; 000399164800019

الاتاحة: http://hdl.handle.net/10138/234743

المؤلفون: Aulin, Linda B. S., Valitalo, Pyry A., Rizk, Matthew L., Visser, Sandra A. G., Rao, Gauri, van der Graaf, Piet H., van Hasselt, J. G. Coen

المساهمون: Leiden University

المصدر: Pharmaceutical Research ; volume 35, issue 2 ; ISSN 0724-8741 1573-904X

الاتاحة: http://dx.doi.org/10.1007/s11095-017-2336-7
http://link.springer.com/article/10.1007/s11095-017-2336-7/fulltext.html
http://link.springer.com/content/pdf/10.1007/s11095-017-2336-7.pdf

المؤلفون: Yamamoto, Yumi, Valitalo, Pyry A., van den Berg, Dirk-Jan, Hartman, Robin, van den Brink, Willem, Wong, Yin Cheong, Huntjens, Dymphy R., Proost, Johannes H., Vermeulen, An, Krauwinkel, Walter, Bakshi, Suruchi, Aranzana-Climent, Vincent, Marchand, Sandrine, Dahyot-Fizelier, Claire, Couet, William, Danhof, Meindert, van Hasselt, Johan G. C., de lange, Elizabeth C. M.

المصدر: Yamamoto , Y , Valitalo , P A , van den Berg , D-J , Hartman , R , van den Brink , W , Wong , Y C , Huntjens , D R , Proost , J H , Vermeulen , A , Krauwinkel , W , Bakshi , S , Aranzana-Climent , V , Marchand , S , Dahyot-Fizelier , C , Couet , W , Danhof , M , van Hasselt , J G C & de lange , E C M 2017 , ' A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows ....

مصطلحات موضوعية: blood-brain barrier, central nervous system (CNS), human prediction, pharmacokinetics, translational model, CENTRAL-NERVOUS-SYSTEM, CEREBROSPINAL-FLUID SYSTEM, PLASMA-PROTEIN BINDING, P-GLYCOPROTEIN, CHOROID-PLEXUS, PHARMACOKINETIC MODEL, BARRIER PERMEABILITY, CISTERNA-MAGNA, BULK FLOW, RAT-BRAIN

وصف الملف: application/pdf

Relation: https://research.rug.nl/en/publications/3aa40e39-3c25-4321-922d-9c635d2c8422

الاتاحة: https://hdl.handle.net/11370/3aa40e39-3c25-4321-922d-9c635d2c8422
https://research.rug.nl/en/publications/3aa40e39-3c25-4321-922d-9c635d2c8422
https://doi.org/10.1007/s11095-016-2065-3
https://pure.rug.nl/ws/files/55674894/10.1007_s11095_016_2065_3.pdf

المؤلفون: Valitalo, Pyry A. J., van den Anker, John N., Allegaert, Karel, de Cock, Roosmarijn F. W., de Hoog, Matthijs, Simons, Sinno H. P., Mouton, Johan W., Knibbe, Catherijne A. J.

مصطلحات موضوعية: Original research

وصف الملف: text/html

Relation: http://jac.oxfordjournals.org/cgi/content/short/dkv052v2; http://dx.doi.org/10.1093/jac/dkv052

الاتاحة: http://jac.oxfordjournals.org/cgi/content/short/dkv052v2
https://doi.org/10.1093/jac/dkv052

المؤلفون: van Rongen, Anne, Brill, Margreke JE, Vaughns, Janelle D., Valitalo, Pyry A. J., van Dongen, Eric P. A., van Ramshorst, Bert, Barrett, Jeffrey S., van den Anker, Johannes N., Knibbe, Catherijne A. J.

المصدر: Clinical Pharmacokinetics. 57(5):601-611

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-354103

المؤلفون: Valitalo, Pyry, Kokki, Merja, Ranta, Veli-Pekka, Olkkola, Klaus T., Hooker, Andrew C., 1973, Kokki, Hannu

المصدر: Pharmaceutical research. 34(5):1125-1133

مصطلحات موضوعية: analgesic, opioid. infant, extremely premature, oxycodone, pain, pharmacokinetics

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-321794

المؤلفون: Janssen, Esther J.H., Valitalo, Pyry A.J., Allegaert, Karel, de Cock, Roosmarijn F.W., Simons, Sinno H.P., Sherwin, Catherine M.T., Mouton, Johan W., van den Anker, John N., Knibbe, Catherijne A.J.

المصدر: Catherine M. Sherwin

مصطلحات موضوعية: Medical Specialties, Medicine and Health Sciences, Pediatrics

Relation: https://works.bepress.com/catherine-sherwin/27

الاتاحة: https://works.bepress.com/catherine-sherwin/27

المؤلفون: Yamamoto, Yumi, Valitalo, Pyry A., Wong, Yin Cheong, Huntjens, Dymphy R., Proost, Johannes H., Vermeulen, An, Krauwinkel, Walter, Beukers, Margot W., Kokki, Hannu, Kokki, Merja, Danhof, Meindert, van Hasselt, Johan G. C., de Lange, Elizabeth C. M.

المصدر: Yamamoto , Y , Valitalo , P A , Wong , Y C , Huntjens , D R , Proost , J H , Vermeulen , A , Krauwinkel , W , Beukers , M W , Kokki , H , Kokki , M , Danhof , M , van Hasselt , J G C & de Lange , E C M 2018 , ' Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach ' , European Journal of Pharmaceutical Sciences , vol. 112 , pp. 168-179 . https://doi.org/10.1016/j.ejps.2017.11.011

مصطلحات موضوعية: Physiology-based pharmacokinetics (PBPK), Blood-brain barrier, Translational modeling, Disease effects, CNS, Active transport, BLOOD-BRAIN-BARRIER, TARGET SITE CONCENTRATIONS, CENTRAL-NERVOUS-SYSTEM, GLYCOPROTEIN-MEDIATED TRANSPORT, POSITRON-EMISSION-TOMOGRAPHY, CELL LINE HCMEC/D3, P-GLYCOPROTEIN, CEREBROSPINAL-FLUID, MULTIDRUG-RESISTANCE, ANTIEPILEPTIC DRUGS

الاتاحة: https://hdl.handle.net/11370/f74cb601-5715-42de-9a80-fec2cb757a3e
https://research.rug.nl/en/publications/f74cb601-5715-42de-9a80-fec2cb757a3e
https://doi.org/10.1016/j.ejps.2017.11.011

المؤلفون: Valitalo, Pyry A. J., van den Anker, John N., Allegaert, Karel, de Cock, Roosmarijn F. W., de Hoog, Matthijs, Simons, Sinno H. P., Mouton, Johan W., Knibbe, Catherijne A. J.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______805::1579fb8f5d144bc73af78b9340a637f7
http://doc.rero.ch/record/297542/files/dkv052.pdf

المؤلفون: Kumpulainen, Elina, Valitalo, Pyry, Kokki, Merja, Lehtonen, Marko, Hooker, Andrew, Ranta, Veli-Pekka, Kokki, Hannu

المصدر: British Journal of Clinical Pharmacology. 70(4):557-566

مصطلحات موضوعية: cerebrospinal fluid, children, flurbiprofen, NONMEM, pain, population pharmacokinetics, MEDICINE, MEDICIN, PHARMACY, FARMACI

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-134562

المؤلفون: Janssen, Esther J.H., Valitalo, Pyry A.J., Allegaert, Karel, de Cock, Roosmarijn F.W., Simons, Sinno H.P., Sherwin, Catherine M.T., Mouton, Johan W., van den Anker, John N., Knibbe, Catherijne A.J.

المصدر: Pediatrics Faculty Publications

مصطلحات موضوعية: Medical Specialties, Medicine and Health Sciences, Pediatrics

Relation: https://corescholar.libraries.wright.edu/pediatrics/196; https://doi.org/10.1128/AAC.01968-15

الاتاحة: https://corescholar.libraries.wright.edu/pediatrics/196
https://doi.org/10.1128/AAC.01968-15

المؤلفون: Valitalo, Pyry A.J., van den Anker, John N., Allegaert, Karel, de Cock, Roosmarijn F.W., de Hoog, Matthijs, Simons, Sinno H.P., Mouton, Johan W., Knibbe, Catherijne A.J.

المصدر: Pediatrics Faculty Publications

مصطلحات موضوعية: Pediatrics

Relation: https://hsrc.himmelfarb.gwu.edu/smhs_peds_facpubs/1145; http://www.ncbi.nlm.nih.gov/pubmed?holding=dcgwulib_fft_ndi&dr=abstract&otool=dcgwulib&term=25765905

الاتاحة: https://hsrc.himmelfarb.gwu.edu/smhs_peds_facpubs/1145
http://www.ncbi.nlm.nih.gov/pubmed?holding=dcgwulib_fft_ndi&dr=abstract&otool=dcgwulib&term=25765905

المؤلفون: Valitalo, Pyry A. J., van den Anker, John N., Allegaert, Karel, de Cock, Roosmarijn F. W., de Hoog, Matthijs, Simons, Sinno H. P., Mouton, Johan W., Knibbe, Catherijne A. J.

URL: http://doc.rero.ch/record/297542/files/dkv052.pdf