المؤلفون: Joanna M. Zakrzewska, Joanne Palmer, Lars Bendtsen, Giulia Di Stefano, Dominik A. Ettlin, Stine Maarbjerg, Mark Obermann, Valerie Morisset, Deb Steiner, Simon Tate, Giorgio Cruccu

المصدر: Trials, Vol 19, Iss 1, Pp 1-10 (2018)

مصطلحات موضوعية: Clinical trial, Vixotrigine, Sodium channel blocker, Underrepresentation, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13063-018-3045-1; https://doaj.org/toc/1745-6215

URL الوصول: https://doaj.org/article/b1e70077314547bc85cf2a9056d7a403

المؤلفون: Brian S Tanaka, Peng Zhao, Fadia B Dib-Hajj, Valerie Morisset, Simon Tate, Stephen G Waxman, Sulayman D Dib-Hajj

المصدر: Molecular Medicine, Vol 22, Iss 1, Pp 338-348 (2016)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.2119/molmed.2016.00131; https://doaj.org/toc/1076-1551; https://doaj.org/toc/1528-3658

URL الوصول: https://doaj.org/article/6dcaf926eb4943dbac1516f15c997730

المؤلفون: Davina Owen, Kevin Gunn, Himanshu Naik, Francois Rugiero, Giuseppe Alvaro, Gerard M. P. Giblin, Dominique Derjean, David R Witty, Valerie Morisset, Simon Tate, David T. MacPherson, Charles Large, Christopher A Hinckley, Joanne Palmer

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: business.industry, Sodium channel, Organic Chemistry, Analgesic, Pharmacology, medicine.disease, Biochemistry, Epilepsy, Sodium channel blocker, Drug development, Trigeminal neuralgia, In vivo, Drug Discovery, Neuropathic pain, medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc02f6ba0cd11da6a81a972adc7f95a
https://doi.org/10.1021/acsmedchemlett.0c00263

المؤلفون: Valérie Morisset, Frédéric Nagy

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.jneurosci.org/content/19/17/7309.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.5880; http://www.jneurosci.org/content/19/17/7309.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.318.5880
http://www.jneurosci.org/content/19/17/7309.full.pdf

المؤلفون: Joi Dunbar, Simon Tate, Beth Tidemann-Miller, Mark Versavel, Himanshu Naik, Joanne Palmer, Valerie Morisset, Yuan Zhao, Gerard M. P. Giblin

المصدر: Clinical pharmacology in drug developmentReferences. 9(1)

مصطلحات موضوعية: Adult, Male, Proline, Cmax, Pharmaceutical Science, Pharmacology, Placebo, 030226 pharmacology & pharmacy, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, Trigeminal neuralgia, medicine, Humans, Pharmacology (medical), Channel blocker, Drug Interactions, Voltage-Gated Sodium Channel Blockers, business.industry, Phenyl Ethers, NAV1.7 Voltage-Gated Sodium Channel, Carbamazepine, Analgesics, Non-Narcotic, medicine.disease, Healthy Volunteers, Discontinuation, Tolerability, 030220 oncology & carcinogenesis, Drug Therapy, Combination, Female, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b06790c78dfdc5b8febd48a577209c
https://pubmed.ncbi.nlm.nih.gov/31650711

المؤلفون: Joanna M Zakrzewska, Valerie Morisset, Gary Layton, Gerard M. P. Giblin, Mark Estacion, Giorgio Cruccu, Dominique Derjean, Kevin Gunn, Simon Tate, Lars Bendtsen, Joanne Palmer, Stephen G. Waxman, Dominik A Ettlin, Mark Obermann

المساهمون: University of Zurich, Zakrzewska, Joanna M

مصطلحات موضوعية: Adult, Male, trigeminal neuralgia, pain, 0301 basic medicine, medicine.medical_specialty, Proline, International Cooperation, Population, Medizin, 610 Medicine & health, Kaplan-Meier Estimate, Placebo, Electrocardiography, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Trigeminal neuralgia, Internal medicine, medicine, Clinical endpoint, Humans, Adverse effect, education, Aged, Retrospective Studies, education.field_of_study, business.industry, Phenyl Ethers, 10223 Clinic for Masticatory Disorders, Carbamazepine, Middle Aged, medicine.disease, Surgery, Clinical trial, Treatment Outcome, 030104 developmental biology, 2728 Neurology (clinical), Tolerability, Area Under Curve, Female, Neurology (clinical), business, 030217 neurology & neurosurgery, Sodium Channel Blockers, medicine.drug

وصف الملف: BB____ZORA____Ettlin___TN_Phase_2_REVISED_9Jan2017.pdf - application/pdf; 16TLN0561_Zakrzewska.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc52cc15917e63cd6eb6494cf9fc018
https://doi.org/10.5167/uzh-135668

المؤلفون: Valerie Morisset, Jon P. Hatcher, Michael Costigan, Paula J. Green, David Grose, Clifford J. Woolf, Andrew Allchorne, Tania O. Stean, Simon Tate, Haibin Wang, Fumimasa Amaya, Martin J. Gunthorpe, Iain P. Chessell, Julie Egerton

المصدر: The Journal of Neuroscience. 26:12852-12860

مصطلحات موضوعية: Male, medicine.medical_specialty, P2Y receptor, TRPV1, Pain, Bradykinin, Sodium Channels, Nav1.9, Mice, chemistry.chemical_compound, Internal medicine, medicine, Animals, Neurons, Afferent, Peripheral Nerves, NAV1.9 Voltage-Gated Sodium Channel, Pain Measurement, Inflammation, Mice, Knockout, Chemistry, General Neuroscience, Sodium channel, Neuropeptides, Purinergic receptor, Articles, Mice, Inbred C57BL, Endocrinology, Hyperalgesia, Capsaicin, Anesthesia, Nociceptor, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0dbf1915fd1c87e72b6fb80bc3bcf10
https://doi.org/10.1523/jneurosci.4015-06.2006

المؤلفون: Andrew D. Randall, Sarah C. Lappin, Martin J. Gunthorpe, Valerie Morisset

المصدر: European Journal of Pharmacology. 540:73-81

مصطلحات موضوعية: Time Factors, Freund's Adjuvant, Central nervous system, TRPV1, TRPV Cation Channels, Neurotransmission, Pharmacology, Biology, Models, Biological, Synaptic Transmission, chemistry.chemical_compound, Glutamatergic, Glutamates, medicine, Animals, Anilides, Neurotransmitter, Inflammation, Glutamate receptor, Excitatory Postsynaptic Potentials, Spinal cord, Rats, Posterior Horn Cells, medicine.anatomical_structure, nervous system, chemistry, Cinnamates, Excitatory postsynaptic potential, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756be690982f32a3da9b54f77d650d0d
https://doi.org/10.1016/j.ejphar.2006.04.046

المؤلفون: Jonathan I. Wilde, Martin J. Gunthorpe, Rejbinder Kaur, Peter G. McLean, Valerie Morisset, N A B Leakey, Laura Rovedatti, Laurens Kruidenier, Kevin Lee, Antonio Di Sabatino, Laurie Scott, Jon T. Brown, J.P. Spencer, Charles H. Knowles, Gino Roberto Corazza, Paolo Biancheri, Thomas T. MacDonald, Neel Sengupta

المصدر: Journal of immunology (Baltimore, Md. : 1950). 183(5)

مصطلحات موضوعية: Interleukin 2, Adult, Patch-Clamp Techniques, T cell, Immunology, Biology, Jurkat cells, Jurkat Cells, Young Adult, Organ Culture Techniques, Interferon, T-Lymphocyte Subsets, Cell Line, Tumor, medicine, Immunology and Allergy, Animals, Humans, Interleukin 8, Intestinal Mucosa, Aged, NFAT, Middle Aged, Calcium Channel Blockers, Inflammatory Bowel Diseases, Molecular biology, T cell cytokine production, Rats, medicine.anatomical_structure, Cell culture, Cytokines, Calcium Channels, T-Box Domain Proteins, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0319aea2b8d0978e4233ef89de979592
https://pubmed.ncbi.nlm.nih.gov/19648266

المؤلفون: Frédéric Nagy, Sandrine S. Bertrand, Gwendal Le Masson, Dominique Derjean, Valerie Morisset, Marc Landry

المصدر: Nature neuroscience. 6(3)

مصطلحات موضوعية: Male, Patch-Clamp Techniques, Potassium Channels, Action Potentials, Sensory system, In Vitro Techniques, Receptors, Metabotropic Glutamate, Synaptic Transmission, GABA Antagonists, Bursting, Spinal Cord Dorsal Horn, Excitatory Amino Acid Agonists, Tonic (music), Animals, Computer Simulation, Patch clamp, Potassium Channels, Inwardly Rectifying, Rats, Wistar, GABA Agonists, Neuronal Plasticity, Chemistry, General Neuroscience, Glutamate receptor, Excitatory Postsynaptic Potentials, Neural Inhibition, Rats, Posterior Horn Cells, Metabotropic receptor, Nociception, nervous system, G Protein-Coupled Inwardly-Rectifying Potassium Channels, Receptors, GABA-B, Female, Neuroscience, Excitatory Amino Acid Antagonists, GABA-B Receptor Antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2615d6b8a1a95b740df7b6fc82ae255
https://pubmed.ncbi.nlm.nih.gov/12601378

المؤلفون: Valerie Morisset, Laszlo Urban, Jatinder Ahluwalia, István Nagy

المصدر: European journal of pharmacology. 429(1-3)

مصطلحات موضوعية: Pharmacology, Analgesics, Cannabinoid receptor, Chemistry, Cannabinoids, medicine.medical_treatment, Receptors, Drug, TRPV1, Anandamide, Inhibitory postsynaptic potential, Depolarization-induced suppression of inhibition, chemistry.chemical_compound, Spinal Cord, medicine, Excitatory postsynaptic potential, Cannabinoid receptor type 2, Animals, Humans, lipids (amino acids, peptides, and proteins), Cannabinoid, Receptors, Cannabinoid, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85f7f4c90e65dcc296784ab5b7a0c9e
https://pubmed.ncbi.nlm.nih.gov/11698030

المؤلفون: Joanna M Zakrzewska, Mark Obermann, Simon Tate, Gerard M. P. Giblin, Dominik A Ettlin, Kevin Gunn, Joanne Palmer, Valerie Morisset

المساهمون: University of Zurich, Zakrzewska, Joanna M

المصدر: Trials

مصطلحات موضوعية: Proline, Medizin, Medicine (miscellaneous), 610 Medicine & health, Placebo, Neuropathic pain, Double-blind randomized withdrawal study, law.invention, Study Protocol, Randomized controlled trial, Double-Blind Method, law, Trigeminal neuralgia, Outcome Assessment, Health Care, medicine, 2736 Pharmacology (medical), Humans, Pharmacology (medical), Oxcarbazepine, Sodium channel blocker, business.industry, Phenyl Ethers, 10223 Clinic for Masticatory Disorders, 2701 Medicine (miscellaneous), Carbamazepine, Trigeminal Neuralgia, medicine.disease, Clinical trial, Tolerability, Withholding Treatment, Research Design, Anesthesia, business, medicine.drug, Sodium Channel Blockers

وصف الملف: Ettlin_Zakrzewska_Methodology_trial_of_CNV_4802_Trials_2013.pdf - application/pdf; 85648.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ffc35ad671f0bd245a08313fb5be64
http://europepmc.org/articles/PMC4222641