المؤلفون: Gianluca Trinco, Valentina Arkhipova, Alisa A. Garaeva, Cedric A. J. Hutter, Markus A. Seeger, Albert Guskov, Dirk J. Slotboom

المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/76bc5140efca4c9482b7af7a5ab080f1

المؤلفون: Alexander Autenshlyus, Sergey Arkhipov, Elena Mikhaylova, Igor Marinkin, Valentina Arkhipova, Nikolay Varaksin, Valentin Vavilin, Vyacheslav Lyahovich

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/5b71126638954a74835f62d44edde586

المؤلفون: Valentina Arkhipova, Albert Guskov, Dirk J. Slotboom

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/5a15e2c8a0a34570bdd68f209b8447e0

المؤلفون: Linda E. Franken, Gert T. Oostergetel, Tjaard Pijning, Pranav Puri, Valentina Arkhipova, Egbert J. Boekema, Bert Poolman, Albert Guskov

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/399c1c026c834306bf7b09a8915fb0a1

المؤلفون: Valentina Arkhipova, Gianluca Trinco, Thijs W Ettema, Sonja Jensen, Dirk J Slotboom, Albert Guskov

المصدر: eLife, Vol 8 (2019)

مصطلحات موضوعية: excitatory amino acid transporters, glutamate transporters, enantiomer, membrane transport, Thermococcus kodakarensis, X-ray crystallography, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/45286; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/91d19203cca24f6ba8ff386f46770454

المؤلفون: Birgit Märtens, Gustavo Arruda Bezerra, Mathias Josef Kreuter, Irina Grishkovskaya, Andrea Manica, Valentina Arkhipova, Kristina Djinovic-Carugo, Udo Bläsi

المصدر: Life, Vol 5, Iss 2, Pp 1264-1281 (2015)

مصطلحات موضوعية: Sulfolbus solfataricus, Sm proteins, structure, Science

وصف الملف: electronic resource

Relation: http://www.mdpi.com/2075-1729/5/2/1264; https://doaj.org/toc/2075-1729

URL الوصول: https://doaj.org/article/d8c8ab3af2af43d3b0fd026202929b27

المؤلفون: Valentina Arkhipova (9993187), Haigen Fu (1721065), Mark W. H. Hoorens (9993190), Gianluca Trinco (4689568), Lucien N. Lameijer (2117944), Egor Marin (9993193), Ben L. Feringa (1429174), Gerrit J. Poelarends (1264938), Wiktor Szymanski (1459837), Dirk J. Slotboom (1553089), Albert Guskov (290146)

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Pharmacology, Biotechnology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, cis configuration, TBOA, photocontrolled ligands, photoresponsive molecules, light-induced modulation, Glutamate Transporter Homologue Pho., side effects, spatiotemporal precision, photocaged compound ONB-hydroxyaspa., transporter dynamics, neurodegenerative diseases, Structural Aspects, glutamate transporters, design challenge, glutamate transporter homologue Glt Tk, crystal structures, Photocaged Inhibitors, time-resolved X-ray crystallography, drug selectivity

Relation: https://figshare.com/articles/journal_contribution/Structural_Aspects_of_Photopharmacology_Insight_into_the_Binding_of_Photoswitchable_and_Photocaged_Inhibitors_to_the_Glutamate_Transporter_Homologue/13584820

الاتاحة: https://doi.org/10.1021/jacs.0c11336.s001

المؤلفون: Christopher R. Smith, Svitlana Kulyk, Misbha Ud Din Ahmad, Valentina Arkhipova, James G. Christensen, Robin J. Gunn, Anthony Ivetac, John M. Ketcham, Jon Kuehler, J. David Lawson, Nicole C. Thomas, Xiaolun Wang, Matthew A. Marx

المصدر: RSC Medicinal Chemistry. 13:1549-1564

مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c927f9ba7684ab99a67e20faf2bf6f
https://doi.org/10.1039/d2md00163b

المؤلفون: Mark W. H. Hoorens, Wiktor Szymanski, Albert Guskov, Valentina Arkhipova, Gerrit J. Poelarends, Egor Marin, Ben L. Feringa, Haigen Fu, Gianluca Trinco, Lucien N. Lameijer, Dirk Jan Slotboom

المساهمون: Enzymology, Chemical and Pharmaceutical Biology, Synthetic Organic Chemistry, Medicinal Chemistry and Bioanalysis (MCB), Biopharmaceuticals, Discovery, Design and Delivery (BDDD), ​Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), X-ray Crystallography

المصدر: Journal of the American Chemical Society
Journal of the American Chemical Society, 143(3), 1513-1520. AMER CHEMICAL SOC
Journal of the American Chemical Society 143(3), 1513-1520 (2021). doi:10.1021/jacs.0c11336

مصطلحات موضوعية: Ultraviolet Rays, Amino Acid Transport System X-AG, 010402 general chemistry, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Catalysis, Article, Colloid and Surface Chemistry, Aspartic Acid, biology, Excitatory amino-acid transporter, Chemistry, Transporter, Stereoisomerism, General Chemistry, 0104 chemical sciences, Thermococcus, Inhibitory potency, ddc:540, biology.protein, Biophysics, Trans-acting, Pharmacophore, Azo Compounds, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2aa4048532a08da41c9ced3fc56ba77
http://europepmc.org/articles/PMC7844824

المؤلفون: Markus A. Seeger, Albert Guskov, Dirk Jan Slotboom, Alisa A Garaeva, Cedric A. J. Hutter, Gianluca Trinco, Valentina Arkhipova

المساهمون: Enzymology, X-ray Crystallography, Groningen Biomolecular Sciences and Biotechnology

المصدر: Communications biology, 4:751. Nature Publishing Group
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology

مصطلحات موضوعية: endocrine system diseases, QH301-705.5, Sodium, Proteolipids, Population, Kinetics, Medicine (miscellaneous), chemistry.chemical_element, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Cryoelectron microscopy, Membrane proteins, Biology (General), education, 030304 developmental biology, 0303 health sciences, education.field_of_study, Aspartic Acid, Chemistry, nutritional and metabolic diseases, Transporter, Biological Transport, Turnover number, Thermococcus, Membrane, Excitatory Amino Acid Transporter 3, Symporter, Biophysics, Aspartate transport, Pyrococcus horikoshii, General Agricultural and Biological Sciences, 030217 neurology & neurosurgery, hormones, hormone substitutes, and hormone antagonists

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065944dd583dcf6dac44a3f9d98c2ed9
https://research.rug.nl/en/publications/a06d8ff0-3d2a-4624-8d9c-fb9ef40145ed

المؤلفون: Tatiana Ivanova, Galina Sokolova, Anna Ivanova, Valentina Arkhipova, Victor N. Orlov

المصدر: Advances in Social Science, Education and Humanities Research.

مصطلحات موضوعية: Development (topology), Russian economy, Business, Economic system

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9d600e981df1632b3247fdfbea2444e1
https://doi.org/10.2991/assehr.k.210322.166

المؤلفون: Michael Rukavishnikov, Ekaterina Mogilnaya, Elena Mikhailova, Sergey Arkhipov, A I Autenshlyus, Nikolay Varaksin, Valentina Arkhipova, Igor Marinkin

المصدر: International Journal of Immunopathology and Pharmacology

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, medicine.medical_specialty, polyclonal activators, medicine.medical_treatment, Immunology, Breast Neoplasms, Adenocarcinoma, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Interferon, Internal medicine, metastasis into regional lymph nodes, cytokine, Tumor Microenvironment, Immunology and Allergy, Medicine, Humans, Letters to the Editor, mammary adenocarcinoma, Phytohaemagglutinin, Aged, Pharmacology, biology, business.industry, cytokine-producing potential, Monocyte, Interleukin, Middle Aged, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Cytokine, 030220 oncology & carcinogenesis, Lymphatic Metastasis, biology.protein, Cancer research, Cytokines, Tumor necrosis factor alpha, Female, Lymph, Sentinel Lymph Node, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9cbffb0b9c5666236447f9224260ee
http://europepmc.org/articles/PMC5815260

المؤلفون: Albert Guskov, Valentina Arkhipova, Dirk Jan Slotboom

المساهمون: Molecular Dynamics, Enzymology

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications, 11(1):998. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Synaptic cleft, Protein Conformation, Science, Amino Acid Transport System X-AG, Archaeal Proteins, General Physics and Astronomy, Protomer, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Membrane proteins, lcsh:Science, Protein Structure, Quaternary, Nanodisc, Aspartic Acid, Multidisciplinary, Binding Sites, Symporters, Chemistry, Cryoelectron Microscopy, Transporter, General Chemistry, Lipids, Single Molecule Imaging, Transport protein, Nanostructures, Thermococcus, 030104 developmental biology, Membrane protein, Symporter, Biophysics, lcsh:Q, Pyrococcus horikoshii, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912d7bd925b2dd0f46c0199d3c1313af
https://research.rug.nl/en/publications/e84834f6-a500-42ad-a3d6-4baa71e63d14

المؤلفون: A I Autenshlyus, Elena Mikhailova, Sergey Arkhipov, Nikolay Varaksin, Igor Marinkin, Valentina Arkhipova

المصدر: Technology in Cancer Research & Treatment

مصطلحات موضوعية: Adult, Cancer Research, medicine.medical_treatment, Biopsy, Gene Expression, receptors, Breast Neoplasms, Interleukin 1 receptor, type II, Lymph node metastasis, CSF2RA, Mammary adenocarcinoma, Biology, 03 medical and health sciences, 0302 clinical medicine, medicine, Cluster Analysis, Humans, Receptors, Interleukin-1 Type II, Receptor, mammary adenocarcinoma, 030304 developmental biology, Aged, Neoplasm Staging, 0303 health sciences, Middle Aged, metastasizes, Immunohistochemistry, cytokines, Cytokine, Oncology, ROC Curve, IL1R2, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, 030220 oncology & carcinogenesis, Lymphatic Metastasis, Cancer research, Female, Original Article, Lymph Nodes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4515e7e8211f61c5bd853e4d9cce44
https://pubmed.ncbi.nlm.nih.gov/31635541

المؤلفون: Thijs W Ettema, Valentina Arkhipova, Dirk Jan Slotboom, Gianluca Trinco, Sonja Jensen, Albert Guskov

المساهمون: Enzymology, Molecular Dynamics

المصدر: eLife
'eLife ', vol: 8, pages: e45286-1-e45286-12 (2019)
eLife, Vol 8 (2019)
eLife, 8:e45286. ELIFE SCIENCES PUBLICATIONS LTD

مصطلحات موضوعية: endocrine system diseases, Protein Conformation, Structural Biology and Molecular Biophysics, Amino Acid Transport System X-AG, FEATURES, Crystallography, X-Ray, STOICHIOMETRY, Reuptake, 0302 clinical medicine, SUBSTRATE, enantiomer, CRYSTAL-STRUCTURE, Biology (General), excitatory amino acid transporters, 0303 health sciences, biology, REFINEMENT, Chemistry, General Neuroscience, D-Aspartic Acid, Glutamate receptor, General Medicine, Transport protein, AMINO-ACID, Thermococcus, Medicine, glutamate transporters, Thermococcus kodakarensis, hormones, hormone substitutes, and hormone antagonists, Protein Binding, STRUCTURAL BASIS, Synaptic cleft, QH301-705.5, Science, membrane transport, Short Report, INHIBITION, General Biochemistry, Genetics and Molecular Biology, MECHANISMS, 03 medical and health sciences, Pyrococcus horikoshii, Binding site, X-ray crystallography, 030304 developmental biology, General Immunology and Microbiology, Sodium, RECOGNITION, nutritional and metabolic diseases, Biological Transport, biology.organism_classification, Structural biology, Biophysics, Other, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b634d8644ee4543c5fbdf85c8b36beb
https://hdl.handle.net/11370/bc24c044-6b9a-482c-aaf0-f63fbb6da794

المؤلفون: Valentina Arkhipova, Albert Guskov, Thijs W Ettema, Sonja Jensen, Gianluca Trinco, Dirk Jan Slotboom

مصطلحات موضوعية: D aspartate, biology, Biochemistry, Chemistry, Excitatory amino-acid transporter, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::894308ff934a7578f6a61c6d9280fe5e
https://doi.org/10.7554/elife.45286.015

المؤلفون: Valentina Arkhipova, Tatyana N. Ivanova, Viktor N. Orlov, Iraida Ivanitskaya

المصدر: E3S Web of Conferences, Vol 110, p 02143 (2019)

مصطلحات موضوعية: lcsh:GE1-350, Social condition, Index (economics), Natural resource economics, business.industry, Reproduction (economics), 0211 other engineering and technologies, 02 engineering and technology, 020303 mechanical engineering & transports, 0203 mechanical engineering, Agriculture, 021105 building & construction, Economics, business, lcsh:Environmental sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f4d012a46a5ec49aed3427a38e7c34
https://www.e3s-conferences.org/articles/e3sconf/pdf/2019/36/e3sconf_spbwosce2019_02143.pdf

المؤلفون: Elena Mikhailova, A I Autenshlyus, Sergey Arkhipov, Nikolay Varaksin, Valentina Arkhipova

المصدر: International Journal of Immunopathology and Pharmacology

مصطلحات موضوعية: 0301 basic medicine, Adult, medicine.medical_treatment, Immunology, Population, Breast Neoplasms, Biology, VEGF-A, cytokines of tumor supernatant, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, TNF-R1, Interferon, medicine, Immunology and Allergy, Humans, education, Letter to the Editor, mammary adenocarcinoma, Aged, Pharmacology, education.field_of_study, Carcinoma, Ductal, Breast, VEGF-R2, Interleukin, Middle Aged, medicine.disease, Vascular Endothelial Growth Factor Receptor-2, Vascular endothelial growth factor, 030104 developmental biology, Cytokine, chemistry, Tumor progression, Receptors, Tumor Necrosis Factor, Type I, 030220 oncology & carcinogenesis, TNF-α, Cancer research, Adenocarcinoma, Cytokines, Tumor necrosis factor alpha, Female, Neoplasm Grading, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db54be52033eb8acc507ffa8e6aeba3d
https://pubmed.ncbi.nlm.nih.gov/29985074

المؤلفون: Gerrit J. Poelarends, Ben L. Feringa, Valentina Arkhipova, Gianluca Trinco, Wiktor Szymanski, Dirk Jan Slotboom, Ria H. Duurkens, Haigen Fu, Mark W. H. Hoorens

المساهمون: Synthetic Organic Chemistry, Chemical and Pharmaceutical Biology, Enzymology, Medicinal Chemistry and Bioanalysis (MCB), Biopharmaceuticals, Discovery, Design and Delivery (BDDD), ​Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE)

المصدر: Advanced Therapeutics, 1(2):1800028. Wiley

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, chemistry.chemical_classification, Nervous system, Biochemistry (medical), Glutamate receptor, Pharmaceutical Science, Medicine (miscellaneous), Transporter, 010402 general chemistry, 01 natural sciences, Small molecule, 0104 chemical sciences, Amino acid, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, chemistry, medicine, Extracellular, Biophysics, Moiety, Pharmacology (medical), IC50, Genetics (clinical)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abf1cf360628ebb1eb63e2c56806645
https://doi.org/10.1002/adtp.201800028

المؤلفون: Albert Guskov, Dirk Jan Slotboom, Valentina Arkhipova

المساهمون: Molecular Dynamics, Enzymology

المصدر: The Journal of General Physiology
The Journal of General Physiology, 149(12)

مصطلحات موضوعية: 0301 basic medicine, Physiology, Computer science, DEPENDENT ASPARTATE TRANSPORTER, media_common.quotation_subject, Amino Acid Transport System X-AG, EXTRACELLULAR GATE, Crystallographic data, Reviews, ION-BINDING, Molecular Dynamics Simulation, Crystallography, X-Ray, 03 medical and health sciences, Ion binding, Viewpoint, X ray methods, Animals, Humans, STRUCTURE REFINEMENT, Quality (business), CRYSTAL-STRUCTURES, Functional studies, Reliability (statistics), media_common, Binding Sites, biology, Excitatory amino-acid transporter, Low resolution, Molecular Docking Simulation, BINDING-SITE, Crystallography, 030104 developmental biology, ESCHERICHIA-COLI, biology.protein, BACILLUS-STEAROTHERMOPHILUS, Biological system, PYROCOCCUS-HORIKOSHII, Protein Binding, GLUTAMATE TRANSPORTER HOMOLOG

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d70f2c45b8a784cb0223ed38d08ff3
https://doi.org/10.1085/jgp.201711852