نتائج البحث - "Vaddady, Pavan"

Relation: urn:issn:0091-2700; https://hdl.handle.net/11250/3112070; https://doi.org/10.1002/jcph.2334; cristin:2166276; Journal of clinical pharmacology. 2023, 63 (12), 1387-1397.

الاتاحة: https://hdl.handle.net/11250/3112070
https://doi.org/10.1002/jcph.2334

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5

Academic Journal

Artificial Intelligence for Quantitative Modeling in Drug Discovery and Development: An Innovation and Quality Consortium Perspective on Use Cases and Best Practices

المؤلفون: Terranova, Nadia, Renard, Didier, Shahin, Mohamed H., Menon, Sujatha, Cao, Youfang, Hop, Cornelis E.C.A., Hayes, Sean, Madrasi, Kumpal, Stodtmann, Sven, Tensfeldt, Thomas, Vaddady, Pavan, Ellinwood, Nicholas, Lu, James

المصدر: Clinical Pharmacology & Therapeutics ; volume 115, issue 4, page 658-672 ; ISSN 0009-9236 1532-6535

الاتاحة: http://dx.doi.org/10.1002/cpt.3053
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.3053

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6

Academic Journal

Application of the model‐informed drug development paradigm to datopotamab deruxtecan dose selection for late‐stage development

المؤلفون: Lu, Yasong, Liang, Shuang, Hong, Ying, Tajima, Naoyuki, Patel, Kashyap, Li, Hanbin, Wada, David R., Greenberg, Jon, Petrich, Adam, Zebger‐Gong, Hong, Shuster, Dale, Vaddady, Pavan

المصدر: CPT: Pharmacometrics & Systems Pharmacology ; volume 13, issue 1, page 23-28 ; ISSN 2163-8306 2163-8306

الاتاحة: http://dx.doi.org/10.1002/psp4.13058
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.13058

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7

Academic Journal

ModVizPop: A shiny interface for empowering teams to perform interactive pharmacokinetic/pharmacodynamic simulations

المؤلفون: Vaddady, Pavan, Kandala, Bhargava

المصدر: CPT: Pharmacometrics & Systems Pharmacology ; volume 10, issue 11, page 1323-1331 ; ISSN 2163-8306 2163-8306

الاتاحة: http://dx.doi.org/10.1002/psp4.12697
https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12697
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/psp4.12697
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12697

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8

Academic Journal

1159. Pharmacokinetics, Safety, and Tolerability of Imipenem/Cilastatin/Relebactam in Pediatric Participants With Confirmed or Suspected Gram-negative Bacterial Infections: A Phase 1b, Open-label, Single-Dose Clinical Trial

المؤلفون: Bradley, John S, Makieieva, Nataliia, Tøndel, Camilla, Roilides, Emmanuel, Kelly, Matthew S, Patel, Munjal, Vaddady, Pavan, Maniar, Alok, Zhang, Ying, Paschke, Amanda, Butterton, Joan R, Chen, Luke F

المصدر: Open Forum Infectious Diseases ; volume 8, issue Supplement_1, page S671-S671 ; ISSN 2328-8957

مصطلحات موضوعية: Infectious Diseases, Oncology

الاتاحة: http://dx.doi.org/10.1093/ofid/ofab466.1352
https://academic.oup.com/ofid/article-pdf/8/Supplement_1/S671/41521896/ofab466.1352.pdf

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9

Academic Journal

Artificial Intelligence for Quantitative Modeling in Drug Discovery and Development: An Innovation and Quality Consortium Perspective on Use Cases and Best Practices.

المؤلفون: Terranova, Nadia, Renard, Didier, Shahin, Mohamed H., Menon, Sujatha, Cao, Youfang, Hop, Cornelis E.C.A., Hayes, Sean, Madrasi, Kumpal, Stodtmann, Sven, Tensfeldt, Thomas, Vaddady, Pavan, Ellinwood, Nicholas, Lu, James

المصدر: Clinical Pharmacology & Therapeutics; Apr2024, Vol. 115 Issue 4, p658-672, 15p

مصطلحات موضوعية: DRUG discovery, ARTIFICIAL intelligence, CONSORTIA, DRUG development, NATURAL language processing, BEST practices

10

Academic Journal

Population Pharmacokinetic and Pharmacodynamic Analysis To Evaluate a Switch to Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate in People Living with HIV-1

المؤلفون: Vaddady, Pavan, Kandala, Bhargava, Yee, Ka Lai

المساهمون: Merck Sharp & Dohme Corp.

المصدر: Antimicrobial Agents and Chemotherapy ; volume 64, issue 11 ; ISSN 0066-4804 1098-6596

الاتاحة: http://dx.doi.org/10.1128/aac.00590-20
https://journals.asm.org/doi/pdf/10.1128/AAC.00590-20

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11

Academic Journal

Application of the model‐informed drug development paradigm to datopotamab deruxtecan dose selection for late‐stage development.

المؤلفون: Lu, Yasong, Liang, Shuang, Hong, Ying, Tajima, Naoyuki, Patel, Kashyap, Li, Hanbin, Wada, David R., Greenberg, Jon, Petrich, Adam, Zebger‐Gong, Hong, Shuster, Dale, Vaddady, Pavan

المصدر: CPT: Pharmacometrics & Systems Pharmacology; Jan2024, Vol. 13 Issue 1, p23-28, 6p

مصطلحات موضوعية: DRUG development, INTERSTITIAL lung diseases, NON-small-cell lung carcinoma, LUNGS, ANTIBODY-drug conjugates, PROGRESSION-free survival

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12

Academic Journal

Doravirine Exposure and HIV-1 Suppression after Switching from an Efavirenz-Based Regimen to Doravirine-Lamivudine-Tenofovir Disoproxil Fumarate

المؤلفون: Greaves, Wayne, Wan, Hong, Yee, Ka Lai, Kandala, Bhargava, Vaddady, Pavan, Hwang, Carey

المساهمون: Merck

المصدر: Antimicrobial Agents and Chemotherapy ; volume 63, issue 12 ; ISSN 0066-4804 1098-6596

الاتاحة: http://dx.doi.org/10.1128/aac.01298-19
https://journals.asm.org/doi/pdf/10.1128/AAC.01298-19

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13

Academic Journal

No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Methadone in Participants Receiving Maintenance Opioid Agonist Therapy

المؤلفون: Feng, Hwa‐Ping, Guo, Zifang, Caro, Luzelena, Marshall, William L., Liu, Fang, Panebianco, Deborah, Vaddady, Pavan, Reitmann, Christina, Jumes, Patricia, Wolford, Dennis, Fraser, Iain, Valesky, Robert, Martinho, Monika, Butterton, Joan R., Iwamoto, Marian, Webster, Lynn, Yeh, Wendy W.

المساهمون: Merck

المصدر: Clinical and Translational Science ; volume 11, issue 6, page 553-561 ; ISSN 1752-8054 1752-8062

الاتاحة: http://dx.doi.org/10.1111/cts.12564
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fcts.12564
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12564

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14

Academic Journal

No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Buprenorphine/Naloxone in Healthy Participants and Participants Receiving Stable Opioid Agonist Therapy

المؤلفون: Feng, Hwa‐Ping, Guo, Zifang, Caro, Luzelena, Marshall, William L., Liu, Fang, Panebianco, Deborah, Vaddady, Pavan, Barbour, April, Reitmann, Christina, Jumes, Patricia, Gilmartin, Jocelyn, Wolford, Dennis, Valesky, Robert, Martinho, Monika, Butterton, Joan R., Iwamoto, Marian, Fraser, Iain, Webster, Lynn, Yeh, Wendy W.

المساهمون: Merck

المصدر: Clinical and Translational Science ; volume 11, issue 6, page 562-572 ; ISSN 1752-8054 1752-8062

الاتاحة: http://dx.doi.org/10.1111/cts.12565
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fcts.12565
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12565

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15

Academic Journal

A Randomized, Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Novel Insulin Dimer

المؤلفون: Walford, Geoffrey A., Duncan, Kelly E., Hernandez, Moises, Vaddady, Pavan, Hompesch, Marcus, Morrow, Linda, Stoch, S. Aubrey

المصدر: Clinical Pharmacology & Therapeutics ; volume 112, issue 1, page 125-132 ; ISSN 0009-9236 1532-6535

الاتاحة: http://dx.doi.org/10.1002/cpt.2607
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2607
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/cpt.2607
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2607

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16

Academic Journal

Incorporating protein precipitation to resolve hybrid IP-LC-MS assay interference for ultrasensitive quantification of intact therapeutic insulin dimer in human plasma

المؤلفون: Sun, Li, Xu, Yang, Dube, Neal, Anderson, Melanie, Breidinger, Sheila, Vaddady, Pavan, Thornton, Bob, Morrow, Linda, Matthews, Randolph P., Stoch, S. Aubrey, Woolf, Eric J.

المساهمون: Merck

المصدر: Journal of Pharmaceutical and Biomedical Analysis ; volume 212, page 114639 ; ISSN 0731-7085

الاتاحة: http://dx.doi.org/10.1016/j.jpba.2022.114639
https://api.elsevier.com/content/article/PII:S0731708522000607?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0731708522000607?httpAccept=text/plain

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17

Academic Journal

Dynamic time-kill curve characterization of spectinamide antibiotics 1445 and 1599 for the treatment of tuberculosis

المؤلفون: Vaddady, Pavan K., Trivedi, Ashit, Rathi, Chetan, Madhura, Dora B., Liu, Jiuyu, Lee, Richard E., Meibohm, Bernd

المساهمون: National Institute of Allergy and Infectious Diseases, NIH Office of the Director, St. Jude Children's Research Hospital

المصدر: European Journal of Pharmaceutical Sciences ; volume 127, page 233-239 ; ISSN 0928-0987

الاتاحة: http://dx.doi.org/10.1016/j.ejps.2018.11.006
https://api.elsevier.com/content/article/PII:S0928098718304974?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0928098718304974?httpAccept=text/plain

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18

Academic Journal

Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux

المصدر: Lee, Richard E; Hurdle, Julian G; Liu, Jiuyu; Bruhn, David F; Matt, Tanja; Scherman, Michael S; Vaddady, Pavan K; Zheng, Zhong; Qi, Jianjun; Akbergenov, Rashid; Das, Sourav; Madhura, Dora B; Rathi, Chetan; Trivedi, Ashit; Villellas, Cristina; Lee, Robin B; Rakesh, Rakesh; Waidyarachchi, Samanthi L; Sun, Dianqing; McNeil, Michael R; Ainsa, Jose A; Boshoff, Helena I; Gonzalez-Juarrero, Mercedes; Meibohm, Bernd; Böttger, Erik C; Lenaerts, Anne J (2014). Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux. Nature Medicine, 20(2):152-158.

مصطلحات موضوعية: Institute of Medical Microbiology, 570 Life sciences, biology, 610 Medicine & health

Relation: https://www.zora.uzh.ch/93019; info:pmid/24464186; urn:issn:1078-8956

الاتاحة: https://www.zora.uzh.ch/id/eprint/93019/
https://www.zora.uzh.ch/93019
https://doi.org/10.1038/nm.3458

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