يعرض 1 - 3 نتائج من 3 نتيجة بحث عن '"V654A"', وقت الاستعلام: 0.47s تنقيح النتائج
  1. 1
    The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor

    المؤلفون: Benjamin D. Medina, Jennifer K. Loo, Ferdinand Rossi, Joanna H. Maltbaek, Adrian M. Seifert, Peter Besmer, Cristina R. Antonescu, Shan Zeng, Jennifer Q. Zhang, Benedikt Bosbach, Nesteene J. Param, Ronald P. DeMatteo, Gerardo A. Vitiello

    المصدر: Oncogene

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Carcinogenesis, Gastrointestinal Stromal Tumors, Kit mutation, Biology, medicine.disease_cause, Article, STAT activation, 03 medical and health sciences, symbols.namesake, Mice, 0302 clinical medicine, Genetics, medicine, Tumor Microenvironment, Animals, Humans, Stromal tumor, Molecular Biology, neoplasms, Gastrointestinal Neoplasms, GiST, Sunitinib, Imatinib, medicine.disease, digestive system diseases, Interstitial cell of Cajal, Disease Models, Animal, Proto-Oncogene Proteins c-kit, STAT Transcription Factors, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation (genetic algorithm), Mutation, Cancer research, symbols, imatinib resistance, Sarcoma, V654A, Gastrointestinal stromal tumor, medicine.drug, Signal Transduction

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e77a9a839eeee1e4303a85424a18c07
    https://pubmed.ncbi.nlm.nih.gov/33024275

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  2. 2
    Academic Journal
    Study of the role of “gatekeeper” mutations V654A and T670I of c-kit kinase in the interaction with inhibitors by means mixed molecular dynamics/docking approach

    المؤلفون: TUTONE, Marco, LAURIA, Antonino, ALMERICO, Anna Maria

    المساهمون: TUTONE, M, LAURIA, A, ALMERICO,AM

    مصطلحات موضوعية: c-kit “gatekeeper” mutants V654A and T670I induced-fit docking, Settore CHIM/08 - Chimica Farmaceutica

    Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000449384800005; volume:7; firstpage:296; lastpage:298; numberofpages:3; journal:BIOINFORMATION; http://hdl.handle.net/10447/64268; http://www.bioinformation.net/007/97320630007296.pdf

    الاتاحة: http://hdl.handle.net/10447/64268
    http://www.bioinformation.net/007/97320630007296.pdf

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  3. 3
    Study of the role of 'gatekeeper' mutations V654A and T670I of c-kit kinase in the interaction with inhibitors by means mixed molecular dynamics/docking approach

    المؤلفون: Anna Maria Almerico, Marco Tutone, Antonino Lauria

    المساهمون: TUTONE, M, LAURIA, A, ALMERICO,AM

    المصدر: Bioinformation

    مصطلحات موضوعية: Stromal cell, business.industry, Kinase, Sunitinib, Mutant, Imatinib, c-kit “gatekeeper” mutants V654A and T670I induced-fit docking, General Medicine, Hypothesis, Pharmacology, Settore CHIM/08 - Chimica Farmaceutica, Haematopoiesis, Docking (molecular), Medicine, business, Tyrosine kinase, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f786aa3f0e99707df45fbf4ec99105
    http://hdl.handle.net/10447/64268

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