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    المساهمون: The research was supported by the Russian Science Found (grant No. 22-25-00222)., Исследование выполнено при финансовой поддержке Российского научного фонда (грант № 22-25-00222).

    المصدر: Advances in Molecular Oncology; Том 10, № 3 (2023); 72-81 ; Успехи молекулярной онкологии; Том 10, № 3 (2023); 72-81 ; 2413-3787 ; 2313-805X ; 10.17650/2313-805X-2023-10-3

    وصف الملف: application/pdf

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    المصدر: Neurology, Neuropsychiatry, Psychosomatics; Vol 15, No 3 (2023); 16-21 ; Неврология, нейропсихиатрия, психосоматика; Vol 15, No 3 (2023); 16-21 ; 2310-1342 ; 2074-2711 ; 10.14412/2074-2711-2023-3

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    Relation: https://nnp.ima-press.net/nnp/article/view/2024/1530; https://nnp.ima-press.net/nnp/article/view/2024/1549; Подколодная ОА, Подколодная НН, Подколодный НЛ. Циркадные часы млекопитающих: генная сеть и компьютерный анализ. Вавиловский журнал генетики и селекции. 2014;18(4/2):928-38.; Vitaterna MH, King DP, Chang AM, et al. Mutagenesis and mapping of a mouse gene, clock, essential for circadian behavior. Science. 1994;264(5159):719-25. doi:10.1126/science.8171325; Ikeda M, Nomura M. cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS protein (BMAL1) and identification of alternatively spliced variants with alternative translation initiation site usage. Biochem Biophys Res Commun. 1997;233(1):258-64. doi:10.1128/MCB.16.4.1706; Zhou YD, Barnard M, Tian H, et al. Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system. Proc Natl Acad Sci U S A. 1997;94(2):713-8. doi:10.1073/pnas.94.2.713; Ikeda M, Yu W, Hirai M, et al. cDNA cloning of a novel bHLH-PAS transcription factor superfamily gene, BMAL2: Its mRNA expression, subcellular distribution, and chromosomal localization. Biochem Biophys Res Commun. 2000;275(2):493-502. doi:10.1006/bbrc.2000.3248; Sasaki M, Yoshitane H, Du NH, et al. Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription. J Biol Chem. 2009;284(37):25149-59. doi:10.1074/jbc.M109.040758; Kovanen L, Saarikoski ST, Aromaa A, et al. ARNTL (BMAL1) and NPAS2 Gene Variants Contribute to Fertility and Seasonality. PLoS One. 2010;5(4):e10007. doi:10.1371/journal.pone.0010007; Lavtar P, Rudolf G, Maver A, et al. Association of circadian rhythm genes ARNTL/BMAL1 and CLOCK with multiple sclerosis. PLoS One. 2018;13(1):e0190601. doi:10.1371/journal.pone.0190601; Nievergelt CM, Kripke DF, Barrett TB, et al. Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2006;141B(3):234-41. doi:10.1002/ajmg.b.30252; Robilliard DL, Archer SN, Arendt J, et al. The 3111 clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects. J Sleep Res. 2002;11(4):305-12. doi:10.1046/j.1365-2869.2002.00320.x; Pedrazzoli M, Louzada FM, Pereira DS, et al. Clock polymorphisms and circadian rhythms phenotypes in a sample of the brazilian population. Chronobiol Int. 2007;24(1):1-8. doi:10.1080/07420520601139789; World Health Organization. MONICA Psychosocial Optional Study. Suggested Measurement Instruments. Copenhagen: WHO Regional Office for Europe; 1988.; Spielberger CD. Anxiety as an emotional state. Anxiety: Current trends in theory and research. New York: Academic Press, 1972. Vol. 1. P. 24-49.; MONICA Monograph and Multimedia Sourcebook. Helsinki; 2003; 237 p.; Бююль А, Цёфель П SPSS: искусство обработки информации. Анализ статистических данных и восстановление скрытых закономерностей. Пер с нем. СПб.: ООО «DiaSoftЮП». 2015. 608 c.; Pandis N. The chi-square test. Am J Orthod Dentofacial Orthop. 2016;150(5):898-9. doi:10.1016/j.ajodo.2016.08.009; Шарашова ЕЕ, Холматова КК, Горбатова МА, Гржибовский АМ. Применение множественного логистического регрессионного анализа в здравоохранении с использованием пакета статистических программ SPSS. Наука и здравоохранение. 2017;(4):5-26.; Papadimitriou GN, Linkowski P. Sleep disturbance in anxiety disorders. Int Rev Psychiatry. 2005;17(4):229-36. doi:10.1080/09540260500104524; Takahashi JS, Hong H-K, Ko CH, McDearmon EL. The genetics of mammalian circadian order and disorder: Implications for physiology and disease. Nat Rev Genet. 2008;9:764-75. doi:10.1038/nrg2430; Rosbash M, Bradley S, Kadener S, et al. Transcriptional feedback and definition of the circadian pacemaker in Drosophila and animals. Cold Spring Harb Symp Quant Biol. 2007;72:75-83. doi:10.1101/sqb.2007.72.062; Rijo-Ferreira F, Takahashi JS. Genomics of circadian rhythms in health and disease. Genome Med. 2019;11:82. doi:10.1186/s13073019-0704-0; Corbett BA, Schupp CW, Levine S, Mendoza S. Comparing cortisol, stress, and sensory sensitivity in children with autism. Autism Res. 2009;2:39-49. doi:10.1002/aur.64; Landgraf D, Long JE, Proulx CD, et al. Genetic Disruption of Circadian Rhythms in the Suprachiasmatic Nucleus Causes Helplessness, Behavioral Despair, and Anxietylike Behavior in Mice. Biol Psychiatry. 2016;80(11):827-35. doi:10.1016/j.biopsych.2016.03.1050; Hogenesch JB, Gu YZ, Jain S, Bradfield CA. The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors. Proc Natl Acad Sci USA. 1998;95:5474-9. doi:10.1073/pnas.95.10.5474; Bunger MK, Wilsbacher LD, Moran SM, et al. Mop3 is an essential component of the master circadian pacemaker in mammals. Cell. 2000;103:1009-17. doi:10.1016/s00928674(00)00205-1; Partonen T, Treutlein J, Alpman A, et al. Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression. Ann Med. 2007;39:229-38. doi:10.1080/07853890701278795; Гафаров ВВ, Гагулин ИВ, Громова ЕА и др. Ассоциация полиморфизма rs2278749 гена ARNTL c некоторыми компонентами аффективных расстройств и нарушениями сна в мужской Новосибирской популяции 25–44 лет. Мир науки, культуры, образования. 2016;6(61):315-9.; https://nnp.ima-press.net/nnp/article/view/2024

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    المساهمون: The investigation has been conducted within government funded scientific topic No. 122031700094-5., Исследование выполнено в рамках бюджетной темы рег. № 122031700094-5.

    المصدر: Neurology, Neuropsychiatry, Psychosomatics; Vol 15, No 1 (2023); 43-49 ; Неврология, нейропсихиатрия, психосоматика; Vol 15, No 1 (2023); 43-49 ; 2310-1342 ; 2074-2711 ; 10.14412/2074-2711-2023-1

    وصف الملف: application/pdf

    Relation: https://nnp.ima-press.net/nnp/article/view/1952/1494; Li Y, Bai W, Zhu B, et al. Prevalence and correlates of poor sleep quality among college students: a cross-sectional survey. Health Qual Life Outcomes. 2020 Jul 1;18(1):210. doi:10.1186/s12955-020-01465-2; Hinz A, Glaesmer H, Brahler E, et al. Sleep quality in the general population: psychometric properties of the Pittsburgh sleep quality index, derived from a German community sample of 9284 people. Sleep Med. 2017 Feb;30:57-63. doi:10.1016/j.sleep.2016.03.008. Epub 2016 May 4.; Covassin N, Singh P. Sleep Duration and Cardiovascular Disease Risk: Epidemiologic and Experimental Evidence. Sleep Med Clin. 2016 Mar;11(1):81-9. doi:10.1016/j.jsmc.2015.10.007. Epub 2016 Jan 9.; Landolt HP, Meier V, Burgess HJ, et al. Serotonin-2 receptors and human sleep: effect of a selective antagonist on EEG power spectra. Neuropsychopharmacology. 1999 Sep;21(3):455-66. doi:10.1016/S0893-133X(99)00052-4; McCormick DA. Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity. Prog Neurobiol. 1992 Oct;39(4):337-88. doi:10.1016/0301-0082(92)90012-4; Gottesmann C. Brain inhibitory mechanisms involved in basic and higher integrated sleep processes. Brain Res Brain Res Rev. 2004 Jul;45(3):230-49. doi:10.1016/j.brainresrev.2004.04.003; Jouvet M. Sleep and serotonin: an unfinished story. Neuropsychopharmacology. 1999 Aug;21(2 Suppl):24S-27S. doi:10.1016/S0893-133X(99)00009-3; Pallesen S, Jacobsen DP, Nielsen MB, Gjerstad J. The 5-HTTLPR rs25531 LALAgenotype increases the risk of insomnia symptoms among shift workers. Sleep Med. 2019 Aug;60:224-9. doi:10.1016/j.sleep.2019.04.009. Epub 2019 Apr 25.; Sookoian S, Gianotti TF, Burgueno A, Pirola CJ. Gene-gene interaction between serotonin transporter (SLC6A4) and CLOCK modulates the risk of metabolic syndrome in rotating shiftworkers. Chronobiol Int. 2010 Jul;27(6):1202-18. doi:10.3109/07420528.2010.496913; Hu XZ, Lipsky RH, Zhu G, et al. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet. 2006 May;78(5):815-26. doi:10.1086/503850. Epub 2006 Mar 28.; Nakamura M, Ueno S, Sano A, Tanabe H. The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants. Mol Psychiatry. 2000;5(1):32-8. doi:10.1038/sj.mp.4000698; Lesch KP, Bengel D, Heils A, et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science. 1996;274(5292):1527-31. doi:10.1038/sj.mp.4000698; Meyer B, Nguyen CB, Moen A, et al. Maintenance of chronic fatigue syndrome (CFS) in young CFS patients is associated with the 5-HTTLPR and SNP rs25531 A > G genotype. PLoS One. 2015 Oct 16;10(10):e0140883. doi:10.1371/journal.pone.0140883. eCollection 2015.; Xie P, Kranzler HR, Poling J, et al. Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations. Arch Gen Psychiatry. 2009;66(11):1201-9. doi:10.1001/archgenpsychiatry.2009.153; Huang C, Li J, Lu LG, et al. Interaction between serotonin transporter gene-linked polymorphic region (5-HTTLPR) and job-related stress in insomnia: a cross-sectional study in Sichuan, China. Sleep Med. 2014;15(10):1269-75. doi:10.1016/j.sleep.2014.01.023; Lonsdorf TB, Ruck C, Bergstrom J, et al. The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism. Prog Neuropsychopharmacol Biol Psychiatry. 2009;33(8):1479-83. doi:10.1016/j.pnpbp.2009.08.004; Lonsdorf TB, Weike AI, Nikamo P, et al. Genetic gating of human fear learning and extinction: possible implications for gene-environment interaction in anxiety disorder. Psychol Sci. 2009;20(2):198-206 doi:10.1111/j.1467-9280.2009.02280.x; Oo KZ, Aung YK, Jenkins MA, Win AK. Associations of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence: A systematic review and meta-analysis. Aust N Z J Psychiatry. 2016;50(9):842-57. doi:10.1177/0004867416637920; Deuschle M, Schredl M, Schilling C, et al. Association between a serotonin transporter length polymorphism and primary insomnia. Sleep. 2010;33(3):343-7. doi:10.1093/sleep/33.3.343; Schroder CM, Primeau MM, Hallmayer JF, et al. Serotonin transporter polymorphism is associated with increased apnea-hypopnea index in older adults. Int J Geriatr Psychiatry. 2014;29(3):227-35. doi:10.1002/gps.3994; Yilmaz M, Bayazit YA, Ciftci TU, et al. Association of serotonin transporter gene polymorphism with obstructive sleep apnea syndrome. Laryngoscope. 2005;115(5):832-6. doi:10.1097/01.MLG.0000157334.88700.E6; Jacobsen DP, Nielsen MB, Einarsen S, Gjerstad J. Negative social acts and pain: Evidence of a workplace bullying and 5-HTT genotype interaction. Scand J Work Environ Health. 2018;44(3):283-90. doi:10.5271/sjweh.3704; Sookoian S, Gemma C, Gianotti TF, et al. Serotonin and serotonin transporter gene variant in rotating shift workers. Sleep. 2007;30(8):1049-53. doi:10.1093/sleep/30.8.1049; World Health Organization. MONICA Psychosocial Optional Study. Suggested Measurement Instruments. Copenhagen: WHO Regional Office for Europe; 1988.; Bühl A., Zöfel P. SPSS Version 10. Einführung in die moderne Datenanalyse unter Windows, 2005. 608 p.; Besedovsky L, Lange T, Haack M. The Sleep-Immune Crosstalk in Health and Disease. Physiol Rev. 2019 Jul 1;99(3):1325-80. doi:10.1152/physrev.00010.2018; Robbins R, Affouf M, Seixas A, et al. Four-Year Trends in Sleep Duration and Quality: A Longitudinal Study Using Data from a Commercially Available Sleep Tracker. J Med Internet Res. 2020 Feb 20;22(2):e14735. doi:10.2196/14735; Вейн АМ, редактор. Вегетативные расстройства: клиника, лечение, диагностика. 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    المساهمون: The study was carried out with the financial support of the Government of the Novosibirsk region within the framework of the State Budget No. 122031700094-5 of Research Institutе of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences., Исследование выполнено при финансовой поддержке Правительства Новосибирской области в рамках ГЗ № 122031700094-5.

    المصدر: Bulletin of Siberian Medicine; Том 22, № 2 (2023); 39-45 ; Бюллетень сибирской медицины; Том 22, № 2 (2023); 39-45 ; 1819-3684 ; 1682-0363 ; 10.20538/1682-0363-2023-22-2

    وصف الملف: application/pdf

    Relation: https://bulletin.ssmu.ru/jour/article/view/5218/3391; https://bulletin.ssmu.ru/jour/article/view/5218/3414; King D., Armstrong M.J. Overview of Gilbert’s syndrome. Drug Ther. Bull. 2019;57(2):27–31. DOI:10.1136/dtb.2018.000028. PMID: 30709860.; Kringen M.K., Piehler A.P., Grimholt R.M., Opdal M.S., Haug K.B., Urdal P. Serum bilirubin concentration in healthy adult North-Europeans is strictly controlled by the UGT1A1 TA-repeat variants. PLoS One. 2014;9(2):e90248. DOI:10.1371/journal.pone.0090248.; Maruo Y., D’Addario C., Mori A., Iwai M., Takahashi H., Sato H. et al. Two linked polymorphic mutations (A(TA)7TAA and T-3279G) of UGT1A1 as the principal cause of Gilbert syndrome. Hum. Genet. 2004;115(6):525–526. DOI:10.1007/s00439-004-1183-x.; Steventon G. Uridine diphosphate glucuronosyltransferase 1A1. Xenobiotica. 2020;50(1):64–76. DOI:10.1080/00498254.2019.1617910.; Gazzin S., Masutti F., Vitek L., Tiribelli C. The molecular basis of jaundice: An old symptom revisited. Liver Int. 2017;37(8):1094–1102. DOI:10.1111/liv.13351.; Udomuksorn W., Elliot D.J., Lewis B.C., Mackenzie P.I., Yoovathaworn K., Miners J.O. Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates. Pharmacogenet Genomics. 2007;17(12):1017–1029. DOI:10.1097/FPC.0b013e328256b1b6.; Zhou J., Yang C., Zhu W., Chen S., Zeng Y., Wang J. et al. Identification of Genetic Risk Factors for Neonatal Hyperbilirubinemia in Fujian Province, Southeastern China: A Case-Control Study. Biomed. Res. Int. 2018;2018:7803175. DOI:10.1155/2018/7803175.; Bale G., Avanthi U.S., Padaki N.R., Sharma M., Duvvur N.R., Vishnubhotla V.R.K. Incidence and risk of gallstone disease in Gilbert’s syndrome patients in indian population. J. Clin. Exp. Hepatol. 2018;8(4):362–366. DOI:10.1016/j.jceh.2017.12.006.; Sugatani J., Yamakawa K., Yoshinari K., Machida T., Takagi H., Mori M. et al. Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia. Biochem. Biophys. Res. Commun. 2002;292(2):492– 497. DOI:10.1006/bbrc.2002.6683.; https://bulletin.ssmu.ru/jour/article/view/5218