المؤلفون: Mirza, Sarah L., Upton, Paul D., Hodgson, Joshua, Gräf, Stefan, Morrell, Nicholas W., Dunmore, Benjamin J.

المساهمون: Wellcome Trust, British Heart Foundation

المصدر: Vascular Pharmacology ; volume 155, page 107381 ; ISSN 1537-1891

الاتاحة: https://doi.org/10.1016/j.vph.2024.107381
https://api.elsevier.com/content/article/PII:S1537189124001071?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1537189124001071?httpAccept=text/plain

المؤلفون: Liu, Bin, Azfar, Mujahid, Legchenko, Ekaterina, West, James A, Martin, Shaun, Van den Haute, Chris, Baekelandt, Veerle, Wharton, John, Howard, Luke, Wilkins, Martin R, Vangheluwe, Peter, Morrell, Nicholas W, Upton, Paul D

مصطلحات موضوعية: 3208 Medical Physiology, 32 Biomedical and Clinical Sciences, Rare Diseases, Lung, 2.1 Biological and endogenous factors, 2 Aetiology, Cardiovascular

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/365614; https://doi.org/10.17863/CAM.106847

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/365614
https://doi.org/10.17863/CAM.106847

المؤلفون: Mirza, Sarah L, Upton, Paul D, Hodgson, Joshua, Gräf, Stefan, Morrell, Nicholas W, Dunmore, Benjamin J

مصطلحات موضوعية: Angiogenesis, Endothelial cells, bone morphogenetic protein, Migration, Pulmonary arterial hypertension, Semaphorin 3 g, Vascular endothelial growth factor, Humans, Cell Movement, Semaphorins, Growth Differentiation Factor 2, Signal Transduction, Vascular Endothelial Growth Factor A, Smad5 Protein, Activin Receptors, Type I, Bone Morphogenetic Protein Receptors, Type II, Smad1 Protein, Lung, Neovascularization, Physiologic, Cells, Cultured

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/368969

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/368969

المؤلفون: Gräf, Stefan, Haimel, Matthias, Bleda, Marta, Hadinnapola, Charaka, Southgate, Laura, Li, Wei, Hodgson, Joshua, Liu, Bin, Salmon, Richard M, Southwood, Mark, Machado, Rajiv D, Martin, Jennifer M, Treacy, Carmen M, Yates, Katherine, Daugherty, Louise C, Shamardina, Olga, Whitehorn, Deborah, Holden, Simon, Aldred, Micheala, Bogaard, Harm J, Church, Colin, Coghlan, Gerry, Condliffe, Robin, Corris, Paul A, Danesino, Cesare, Eyries, Mélanie, Gall, Henning, Ghio, Stefano, Ghofrani, Hossein-Ardeschir, Gibbs, J Simon R, Girerd, Barbara, Houweling, Arjan C, Howard, Luke, Humbert, Marc, Kiely, David G, Kovacs, Gabor, MacKenzie Ross, Robert V, Moledina, Shahin, Montani, David, Newnham, Michael, Olschewski, Andrea, Olschewski, Horst, Peacock, Andrew J, Pepke-Zaba, Joanna, Prokopenko, Inga, Rhodes, Christopher J, Scelsi, Laura, Seeger, Werner, Soubrier, Florent, Stein, Dan F, Suntharalingam, Jay, Swietlik, Emilia M, Toshner, Mark R, van Heel, David A, Vonk Noordegraaf, Anton, Waisfisz, Quinten, Wharton, John, Wort, Stephen J, Ouwehand, Willem H, Soranzo, Nicole, Lawrie, Allan, Upton, Paul D, Wilkins, Martin R, Trembath, Richard C, Morrell, Nicholas W

المصدر: Nature communications. 9(1)

مصطلحات موضوعية: Humans, Genetic Predisposition to Disease, Transforming Growth Factor beta, Membrane Transport Proteins, Prognosis, Case-Control Studies, Signal Transduction, Gene Expression Regulation, Base Sequence, Mutation, Models, Molecular, Adult, Female, Male, Aquaporin 1, Bone Morphogenetic Protein Receptors, Type II, Adenosine Triphosphatases, Growth Differentiation Factors, SOXF Transcription Factors, HEK293 Cells, Familial Primary Pulmonary Hypertension, Whole Genome Sequencing, Bone Morphogenetic Protein Receptors, Type II, Models, Molecular

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6q66073b

المؤلفون: Andersson-Rusch, Clara Leticia, Liu, Bin, Quist-Løkken, Ingrid, Upton, Paul D., Olsen, Oddrun Elise, Hella, Hanne, Yang, Xudong, Tong, Zhen, Morrell, Nicholas W., Holien, Toril, Li, Wei

المصدر: 13 ; Scientific Reports ; 6639

وصف الملف: application/pdf

Relation: urn:issn:2045-2322; https://hdl.handle.net/11250/3100966; https://doi.org/10.1038/s41598-023-33352-3; cristin:2147443

الاتاحة: https://hdl.handle.net/11250/3100966
https://doi.org/10.1038/s41598-023-33352-3

المؤلفون: Dunmore, Benjamin J., Upton, Paul D., Auckland, Kate, Samanta, Romit J., Lyons, Paul A., Smith, Kenneth G. C., Gräf, Stefan, Summers, Charlotte, Morrell, Nicholas W.

المساهمون: National Institute for Health Research, British Heart Foundation, Medical Research Council

المصدر: Pulmonary Circulation ; volume 13, issue 1 ; ISSN 2045-8940 2045-8940

الاتاحة: http://dx.doi.org/10.1002/pul2.12192
https://onlinelibrary.wiley.com/doi/pdf/10.1002/pul2.12192
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/pul2.12192

المؤلفون: Romero, M. Pilar, Chang, Yu-Mei, Brunton, Lucy A., Parry, Jessica, Prosser, Alison, Upton, Paul, Drewe, Julian A.

المساهمون: Royal College of Veterinary Surgeons Charitable Trust, Animal and Plant Health Agency, American Pharmacists Association

المصدر: Preventive Veterinary Medicine ; volume 219, page 106004 ; ISSN 0167-5877

الاتاحة: http://dx.doi.org/10.1016/j.prevetmed.2023.106004
https://api.elsevier.com/content/article/PII:S016758772300168X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S016758772300168X?httpAccept=text/plain

المؤلفون: Mitrofan, Claudia-Gabriela, Appleby, Sarah L, Nash, Gerard B, Mallat, Ziad, Chilvers, Edwin R, Upton, Paul D, Morrell, Nicholas W

المصدر: Journal of Biological Chemistry. 292(33)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, 1.1 Normal biological development and functioning, Underpinning research, Aetiology, 2.1 Biological and endogenous factors, Cardiovascular, Activin Receptors, Type I, Activin Receptors, Type II, Aorta, Bone Morphogenetic Proteins, Cell Adhesion, Cells, Cultured, E-Selectin, Endothelium, Vascular, Growth Differentiation Factor 2, Growth Differentiation Factors, Humans, Intercellular Adhesion Molecule-1, Kinetics, Monocytes, Phosphorylation, Protein Kinase Inhibitors, Protein Processing, Post-Translational, Pyrazoles, Pyrimidines, RNA Interference, Signal Transduction, Tumor Necrosis Factor-alpha, Up-Regulation, Vascular Cell Adhesion Molecule-1, SMAD transcription factor, atherosclerosis, bone morphogenetic protein, endothelial cell, monocyte, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/94v0v3rm
https://escholarship.org/content/qt94v0v3rm/qt94v0v3rm.pdf

المؤلفون: Jiang, He, Salmon, Richard M, Upton, Paul D, Wei, Zhenquan, Lawera, Aleksandra, Davenport, Anthony P, Morrell, Nicholas W, Li, Wei

المصدر: Journal of Biological Chemistry. 291(6)

مصطلحات موضوعية: Biochemistry and Cell Biology, Medical Physiology, Biomedical and Clinical Sciences, Biological Sciences, Cardiovascular, Heart Disease, Animals, Bone Morphogenetic Proteins, Cardiomegaly, Cell Line, Endothelial Cells, Heart Atria, Humans, Mice, Rats, Signal Transduction, bone morphogenetic protein, bone morphogenetic protein 10, cell biology, endothelial cell, signal transduction, transforming growth factor beta, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7730g1f6
https://escholarship.org/content/qt7730g1f6/qt7730g1f6.pdf

المؤلفون: Prapa, Matina, Lago-Docampo, Mauro, Swietlik, Emilia M, Montani, David, Eyries, Mélanie, Humbert, Marc, Welch, Carrie L, Chung, Wendy K, Berger, Rolf M F, Bogaard, Harm Jan, Danhaive, Olivier, Escribano-Subías, Pilar, Gall, Henning, Girerd, Barbara, Hernandez-Gonzalez, Ignacio, Holden, Simon, Hunt, David, Jansen, Samara M A, Kerstjens-Frederikse, Wilhelmina, Kiely, David G, Lapunzina, Pablo, McDermott, John, Moledina, Shahin, Pepke-Zaba, Joanna, Polwarth, Gary J, Schotte, Gwen, Tenorio-Castaño, Jair, Thompson, A A Roger, Wharton, John, Wort, Stephen J, Megy, Karyn, Mapeta, Rutendo, Treacy, Carmen M, Martin, Jennifer M, Li, Wei, Swift, Andrew J, Upton, Paul D, Morrell, Nicholas W, Gräf, Stefan, Valverde, Diana, NIHR BioResource for Translational Research–Rare Diseases, National Cohort Study of Idiopathic and Heritable PAH, PAH Biobank Enrolling Centers’ Investigators

المساهمون: UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service de néonatologie

المصدر: American journal of respiratory and critical care medicine, Vol. 206, no.12, p. 1522-1533 (2022)

مصطلحات موضوعية: Humans, Gain of Function Mutation, T-Box Domain Proteins, Bone Morphogenetic Protein Receptors, Type II, Phenotype, Lung Diseases, Mutation, Genotype, TBX4, gain-of-function, interstitial lung disease, lung developmental disease, pulmonary arterial hypertension

Relation: boreal:278235; http://hdl.handle.net/2078.1/278235; info:pmid/35852389; urn:ISSN:1073-449X; urn:EISSN:1535-4970

الاتاحة: http://hdl.handle.net/2078.1/278235
https://doi.org/10.1164/rccm.202203-0485OC

المؤلفون: Upton, Paul D, Dunmore, Benjamin J, Li, Wei, Morrell, Nicholas W

مصطلحات موضوعية: Humans, Hypertension, Pulmonary, Ligands, Pulmonary Arterial Hypertension, Pulmonary Artery, Signal Transduction, Activins, Bone Morphogenetic Proteins, Cytokines

وصف الملف: text/xml; application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/336505

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/336505
https://doi.org/10.17863/CAM.83922

المؤلفون: Ainscough, Alexander J, Smith, Timothy J, Haensel, Maike, Rhodes, Christopher J, Fellows, Adam, Whitwell, Harry J, Vasilaki, Eleni, Gray, Kelly, Freeman, Adrian, Howard, Luke S, Wharton, John, Dunmore, Benjamin, Upton, Paul D, Wilkins, Martin R, Edel, Joshua B, Wojciak-Stothard, Beata

المصدر: essn: 2399-3642 ; nlmid: 101719179

مصطلحات موضوعية: Humans, Bone Morphogenetic Protein Receptors, Type II, Epoprostenol, Hypertension, Pulmonary, Pulmonary Arterial Hypertension, SOXF Transcription Factors

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/344191

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/344191
https://doi.org/10.17863/CAM.91615

المؤلفون: Ruiz-Llorente, Lidia, Vega, M Cristina, Fernández, Francisco J, Langa, Carmen, Morrell, Nicholas W, Upton, Paul D, Bernabeu, Carmelo

المصدر: essn: 1422-0067 ; nlmid: 101092791

مصطلحات موضوعية: BMP, GFP, TGF-β, endoglin, endothelium, fluorescence, fusion protein, recombinant protein, soluble endoglin, Animals, Bone Morphogenetic Proteins, CHO Cells, Cricetulus, Green Fluorescent Proteins, Growth Differentiation Factor 2, Humans, Recombinant Fusion Proteins

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/332094

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/332094
https://doi.org/10.17863/CAM.79541

المؤلفون: Hodgson, Joshua, Ruiz-Llorente, Lidia, McDonald, Jamie, Quarrell, Oliver, Ugonna, Kelechi, Bentham, James, Mason, Rebecca, Martin, Jennifer, Moore, David, Bergstrom, Katie, Bayrak-Toydemir, Pinar, Wooderchak-Donahue, Whitney, Morrell, Nicholas W, Condliffe, Robin, Bernabeu, Carmelo, Upton, Paul D

مصطلحات موضوعية: bone morphogenetic protein, hereditary hemorrhagic telangiectasia, pulmonary arterial hypertension, pulmonary arteriovenous malformations, Alleles, Angiography, Bone Morphogenetic Proteins, Cell Line, Child, Codon, Nonsense, Enzyme-Linked Immunosorbent Assay, Genetic Association Studies, Genetic Predisposition to Disease, Growth Differentiation Factor 2, Homozygote, Humans, Phenotype, Syndrome, Telangiectasia, Hereditary Hemorrhagic

وصف الملف: application/pdf; text/xml

Relation: https://www.repository.cam.ac.uk/handle/1810/332039

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/332039
https://doi.org/10.17863/CAM.79486

المؤلفون: Novoyatleva, Tatyana, Rai, Nabham, Kojonazarov, Baktybek, Veeroju, Swathi, Ben-Batalla, Isabel, Caruso, Paola, Shihan, Mazen, Kühn, Nadine, Götz, Elsa, Lepper, Carina, Herpel, Sebastian, Manaud, Grégoire, Perros, Frédéric, Gall, Henning, Ghofrani, Hossein Ardeschir, Weißmann, Norbert, Grimminger, Friedrich, Wharton, John, Wilkins, Martin, Upton, Paul D., Loges, Sonja, Morrell, Nicholas W., Seeger, Werner, Schermuly, Ralph T.

مصطلحات موضوعية: ddc:610

وصف الملف: application/pdf

Relation: https://jlupub.ub.uni-giessen.de//handle/jlupub/7034; http://dx.doi.org/10.22029/jlupub-6485

الاتاحة: https://jlupub.ub.uni-giessen.de//handle/jlupub/7034
https://doi.org/10.22029/jlupub-6485

المؤلفون: Upton, Paul D., Dunmore, Benjamin J., Li, Wei, Morrell, Nicholas W.

المساهمون: NIHR Cambridge Biomedical Research Centre, New York State Department of Health, National Institute on Handicapped Research, British Heart Foundation

المصدر: Developmental Dynamics ; volume 252, issue 3, page 327-342 ; ISSN 1058-8388 1097-0177

الاتاحة: https://doi.org/10.1002/dvdy.478
https://onlinelibrary.wiley.com/doi/pdf/10.1002/dvdy.478
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/dvdy.478

المؤلفون: Upton, Paul, Richards, Susan, Bates, Angela, Niederhoffer, Karen Y., Morrell, Nicholas W., Christian, Susan

المساهمون: British Heart Foundation, NIHR Cambridge Biomedical Research Centre

المصدر: American Journal of Medical Genetics Part A ; volume 191, issue 1, page 228-233 ; ISSN 1552-4825 1552-4833

الاتاحة: http://dx.doi.org/10.1002/ajmg.a.62996
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajmg.a.62996
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ajmg.a.62996

المؤلفون: Novoyatleva, Tatyana, Rai, Nabham, Kojonazarov, Baktybek, Veeroju, Swathi, Ben-Batalla, Isabel, Caruso, Paola, Shihan, Mazen, Presser, Nadine, Götz, Elsa, Lepper, Carina, Herpel, Sebastian, Manaud, Grégoire, Perros, Frédéric, Gall, Henning, Ghofrani, Hossein Ardeschir, Weissmann, Norbert, Grimminger, Friedrich, Wharton, John, Wilkins, Martin, Upton, Paul D., Loges, Sonja, Morrell, Nicholas W., Seeger, Werner, Schermuly, Ralph T.

المصدر: Communications Biology ; volume 5, issue 1 ; ISSN 2399-3642

الاتاحة: https://doi.org/10.1038/s42003-022-03045-0
https://www.nature.com/articles/s42003-022-03045-0.pdf
https://www.nature.com/articles/s42003-022-03045-0

المؤلفون: Ainscough, Alexander J., Smith, Timothy J., Haensel, Maike, Rhodes, Christopher J., Fellows, Adam, Whitwell, Harry J., Vasilaki, Eleni, Gray, Kelly, Freeman, Adrian, Howard, Luke S., Wharton, John, Dunmore, Benjamin, Upton, Paul D., Wilkins, Martin R., Edel, Joshua B., Wojciak-Stothard, Beata

المساهمون: British Heart Foundation

المصدر: Communications Biology ; volume 5, issue 1 ; ISSN 2399-3642

الاتاحة: http://dx.doi.org/10.1038/s42003-022-04169-z
https://www.nature.com/articles/s42003-022-04169-z.pdf
https://www.nature.com/articles/s42003-022-04169-z

المؤلفون: Ruiz-Llorente, Lidia, Vega, María Cristina, Fernández, Francisco J., Langa, Carmen, Morrell, Nicholas W., Upton, Paul D., Bernabéu, Carmelo

المساهمون: Ministerio de Ciencia, Innovación y Universidades (España), Centro de Investigación Biomédica en Red Enfermedades Raras (España), Consejo Superior de Investigaciones Científicas (España), British Heart Foundation, Instituto de Salud Carlos III, European Commission, Ruiz-Llorente, Lidia, Vega, María Cristina, Fernández, Francisco J., Morrell, Nicholas W., Upton, Paul D., Bernabéu, Carmelo

مصطلحات موضوعية: Endoglin, GFP, Soluble endoglin, Fusion protein, Recombinant protein, Fluorescence, BMP, TGF-β, Endothelium

Relation: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO//SAF2013-43421-R/ES/ANALISIS DE UN NUEVO ROL DE ENDOGLINA EN ADHESION CELULAR Y SU RELEVANCIA EN LA BIOLOGIA VASCULAR/; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-102242-B-I00/ES/ACTIVACION ESPONTANEA DE LA VIA ALTERNATIVA DEL COMPLEMENTO Y SU RELEVANCIA EN LA ENFERMEDAD RENAL POR DEPOSITO DENSO/; Publisher's version; https://doi.org/10.3390/ijms222011282; Sí; International Journal of Molecular Sciences 22 (20) 11282 (2021); http://hdl.handle.net/10261/262520; http://dx.doi.org/10.13039/501100000780; http://dx.doi.org/10.13039/501100004587; http://dx.doi.org/10.13039/501100000274; http://dx.doi.org/10.13039/501100003339

الاتاحة: http://hdl.handle.net/10261/262520
https://doi.org/10.3390/ijms222011282
https://doi.org/10.13039/501100000780
https://doi.org/10.13039/501100004587
https://doi.org/10.13039/501100000274
https://doi.org/10.13039/501100003339