نتائج البحث - "Uchic, M. E."

1

Academic Journal

Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A‐841720, a novel non‐competitive mGluR1 receptor antagonist

المؤلفون: El‐Kouhen, O, Lehto, S G, Pan, J B, Chang, R, Baker, S J, Zhong, C, Hollingsworth, P R, Mikusa, J P, Cronin, E A, Chu, K L, McGaraughty, S P, Uchic, M E, Miller, L N, Rodell, N M, Patel, M, Bhatia, P, Mezler, M, Kolasa, T, Zheng, G Z, Fox, G B, Stewart, A O, Decker, M W, Moreland, R B, Brioni, J D, Honore, P

المصدر: British Journal of Pharmacology ; volume 149, issue 6, page 761-774 ; ISSN 0007-1188 1476-5381

الاتاحة: http://dx.doi.org/10.1038/sj.bjp.0706877
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1038%2Fsj.bjp.0706877
https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1038/sj.bjp.0706877

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2

Periodical

Structure−Activity Relationship of Triazafluorenone Derivatives as Potent and Selective mGluR1 Antagonists

المؤلفون: Zheng, G. Z., Bhatia, P., Daanen, J., Kolasa, T., Patel, M., Latshaw, S., Kouhen, O. F. El, Chang, R., Uchic, M. E., Miller, L., Nakane, M., Lehto, S. G., Honore, M. P., Moreland, R. B., Brioni, J. D., Stewart, A. O.

المصدر: Journal of Medicinal Chemistry; November 2005, Vol. 48 Issue: 23 p7374-7388, 15p

3

Periodical

Discovery of 2-(4-Pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a Dopaminergic Agent with a Novel Mode of Action for the Potential Treatment of Erectile Dysfunction

المصدر: Journal of Medicinal Chemistry; July 2004, Vol. 47 Issue: 15 p3853-3864, 12p

4

Academic Journal

Tandem synthesis and antibacterial screening of new thieno[2,3-b]pyridine-fused pyrimidin-4(3H)-ones linked to thiazole or oxazole units.

المؤلفون: Sanad, Sherif M. H., Mekky, Ahmed E. M.

المصدر: Synthetic Communications; 2023, Vol. 53 Issue 13, p994-1007, 14p, 10 Diagrams, 3 Charts

مصطلحات موضوعية: ANTIBACTERIAL agents, THIAZOLES, NEW product development, DIOXANE, MICROWAVES

5

Academic Journal

Recent advances in understanding ion transport mechanisms in polycystic kidney disease.

المؤلفون: Sudarikova, Anastasia V., Vasileva, Valeriia Y., Sultanova, Regina F., Ilatovskaya, Daria V.

المصدر: Clinical Science; Nov2021, Vol. 135 Issue 21, p2521-2540, 20p

مصطلحات موضوعية: POLYCYSTIC kidney disease, TRPV cation channels, PURINERGIC receptors, SODIUM channels

6

Academic Journal

Pituitary Adenylate Cyclase-Activating Polypeptide in Learning and Memory.

المؤلفون: Gilmartin, Marieke R., Ferrara, Nicole C.

المصدر: Frontiers in Cellular Neuroscience; 6/22/2021, Vol. 15, p1-8, 8p

مصطلحات موضوعية: PITUITARY adenylate cyclase activating polypeptide, POST-traumatic stress disorder, POST-traumatic stress, COGNITION

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7

Periodical

Renal epithelial fluid secretion and cyst growth: the role of cyclic AMP

المؤلفون: Mangoo‐Karim, Roberto, Uchic, Marie E., Grant, Michael, Shumate, Wendy A., Calvet, James P., Park, Chan H., Grantham, Jared J.

المصدر: The FASEB Journal; December 1989, Vol. 3 Issue: 14 p2629-2632, 4p

8

Academic Journal

New heterocyclic systems: Pyrido[2′,3′:5,4]thieno(furo)[3,2-d]oxazines as intermediate compounds for the synthesis of substituted pyrido[3′,2′:4,5]thieno(furo)[3,2-d]pyrimidines.

المؤلفون: Sirakanyan, Samvel N., Spinelli, Domenico, Geronikaki, Athina, Hakobyan, Elmira K., Hovakimyan, Anush A.

المصدر: Synthetic Communications; 2019, Vol. 49 Issue 21, p2823-2833, 11p, 4 Diagrams, 3 Charts

مصطلحات موضوعية: PYRIMIDINES, OXAZINES, BENZYL compounds, HYDROCHLORIC acid, POTASSIUM salts, ACETIC anhydride, POTASSIUM hydroxide

9

Academic Journal

The Molecular Determinants of Small-Molecule Ligand Binding at P2X Receptors.

المؤلفون: Pasqualetto, Gaia, Brancale, Andrea, Young, Mark T.

المصدر: Frontiers in Pharmacology; 2/2/2018, p1-N.PAG, 13p

مصطلحات موضوعية: PHARMACOLOGY, MOLECULAR structure

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10

Academic Journal

2-(Aminomethyl)-3-arylindoles from 3-(o-Trifluoroacetamidoaryl)- 1-propargylic Alcohols, Aryl Halides, and Amines: A Domino Palladium-Catalyzed Three-Component Approach.

المؤلفون: Cacchi, Sandro, Fabrizi, Giancarlo, Goggiamani, Antonella, Iazzetti, Antonia, Verdiglione, Rosanna

المصدر: Synthesis; 2017, Vol. 49 Issue 18, p4163-4172, 10p

مصطلحات موضوعية: ARYL halides, ORGANIC compounds, HALOGEN compounds, DEAMINATION, HALIDES

11

Academic Journal

Synthesis of Imidazole and Theophylline Derivatives Incorporating Pyrimidine-Fused Heterocycles Using Magnetic Nanoparticles-Supported Tungstic Acid (MNP-TA) Catalyst.

المؤلفون: Divar, Masoumeh, Panahi, Farhad, Shariatipour, Sayedeh Rojin, Khalafi ‐ Nezhad, Ali

المصدر: Journal of Heterocyclic Chemistry; Jan2017, Vol. 54 Issue 1, p660-669, 10p

مصطلحات موضوعية: IMIDAZOLES, THEOPHYLLINE, TUNGSTIC acid, PYRIMIDINES, HETEROCYCLIC compounds, MAGNETIC nanoparticles, CATALYST supports

12

Academic Journal

The Rearrangment of 3-Aminobenzo-[ b]thiophenes to Tricyclic Benzoisothiazoles as Result of a Simple Azo-coupling Procedure.

المؤلفون: Klimas, Susann, Beckert, Rainer, Hartmann, Horst, Görls, Helmar

المصدر: Journal of Heterocyclic Chemistry; Nov2016, Vol. 53 Issue 6, p2102-2105, 4p

مصطلحات موضوعية: AMINOBENZOIC acids, COUPLING reactions (Chemistry), DIMETHYLAMINOAZOBENZENE, CARBOXYLATES, SULFANYLACETATE

13

Academic Journal

Expression of a Novel D4 Dopamine Receptor in the Lamprey Brain. Evolutionary Considerations about Dopamine Receptors.

المؤلفون: Pérez-Fernández, Juan, Megías, Manuel, Pombal, Manuel A., Puelles, Luis, Armengol, José A.

المصدر: Frontiers in Neuroanatomy; 1/6/2016, p1-17, 17p

مصطلحات موضوعية: DOPAMINE receptors, BRAIN evolution, GENE expression, DOPAMINERGIC neurons, HYPOTHALAMIC hormones

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14

Book

Role of Chemistry in Lead Discovery.

المؤلفون: Rankovic, Zoran, Morphy, Richard

المصدر: Lead Generation Approaches in Drug Discovery; 2010, p259-290, 32p

15

Academic Journal

Use of antiemetics in the prevention of chemotherapy-induced nausea and vomiting: review and focus on the Belgian situation.

المؤلفون: Van den Brande, Jan, Brouwer, Aaltje, Peeters, Marc

المصدر: Acta Gastro-Enterologica Belgica; Jun2014, Vol. 77 Issue 2, p240-248, 9p

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16

Academic Journal

Iodoacetic Acid is an Efficient Reagent for the Synthesis of Amino Acid Derived 2-Aminobenzimidazoles.

المؤلفون: Krasikovs, Andrejs, Ozola, Vita, Dax, Scott L., Suna, Edgars

المصدر: Synthesis; Mar2013, Vol. 45 Issue 5, p0683-0693, 11p

مصطلحات موضوعية: BENZIMIDAZOLES, CHEMICAL synthesis, AMINO acid derivatives, ISOTHIOCYANATES, DESULFURIZATION, THIOUREA, METHYL iodide

17

Academic Journal

Identification of Key Residues for the Binding of Glucagon to the N-Terminal Domain of its Receptor: An Alanine Scan and Modeling Study.

المؤلفون: M. Prévost, P. Vertongen, M. Waelbroeck

المصدر: Hormone & Metabolic Research; Oct2012, Vol. 44 Issue 11, p804-809, 6p

مصطلحات موضوعية: GLUCAGON-like peptide 1, LIGAND binding (Biochemistry), POLYPEPTIDES, GLYCOGENOLYSIS, GLYCOLYSIS, PARACRINE mechanisms, INSULIN resistance, HYPERGLYCEMIA

18

Academic Journal

Spatial proximity between the VPAC1 receptor and the amino terminus of agonist and antagonist peptides reveals distinct sites of interaction.

المؤلفون: Ceraudo, Emilie, Hierso, Régine, Tan, Yossan-Var, Murail, Samuel, Rouyer-Fessard, Christiane, Nicole, Pascal, Robert, Jean-Claude, Jamin, Nadège, Neumann, Jean-Michel, Robberecht, Patrick, Laburthe, Marc, Couvineau, Alain

المصدر: FASEB Journal; May2012, Vol. 26 Issue 5, p2060-2071, 12p

مصطلحات موضوعية: PEPTIDES, ORGANIC compounds, HISTIDINE, AMINO acids, HISTAMINE

19

Academic Journal

Efficient and Novel Synthesis of Benzoxazole Derivatives in the Presence of Zinc Dust Under Solvent-Free Conditions.

المؤلفون: Murty, M. S. R., Ram, KesurR., Rao, RayuduVenkateswara, Yadav, J. S.

المصدر: Synthetic Communications; 2010, Vol. 40 Issue 19, p2844-2849, 6p, 1 Diagram, 2 Charts

مصطلحات موضوعية: ZINC powder, SOLVENTS, MICROWAVE heating, AMINES, OXAZOLES, ZINC

20

Academic Journal

Synthesis of 5,5'-Disubstituted Bimorpholines.

المؤلفون: Lippur, Kristin, Elmers, Cindy, Kailas, Tiiu, Müürisepp, Aleksander-Mati, Pehk, Tõnis, Kanger, Tõnis, Lopp, Margus

المصدر: Synthetic Communications; 2010, Vol. 40 Issue 2, p266-281, 16p, 4 Diagrams, 1 Chart

مصطلحات موضوعية: CHEMICAL reactions, BENZYL compounds, ESTERS, ORGANIC compounds, CHIRAL drugs

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