المؤلفون: Alma C. Salas-Leal, Sergio M. Salas-Pacheco, Erik I. Hernández-Cosaín, Lilia M. Vélez-Vélez, Elizabeth I. Antuna-Salcido, Francisco X. Castellanos-Juárez, Edna M. Méndez-Hernández, Osmel La Llave-León, Gerardo Quiñones-Canales, Oscar Arias-Carrión, Ada A. Sandoval-Carrillo, José M. Salas-Pacheco

المصدر: Frontiers in Molecular Neuroscience, Vol 16 (2023)

مصطلحات موضوعية: Parkinson’s disease, UBE2K, PSMC4, SKP1, HSPA8, protein degradation systems, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2023.1298560/full; https://doaj.org/toc/1662-5099

URL الوصول: https://doaj.org/article/8d300725e5e948b6bf07ed8111dec9a1

المؤلفون: Adam J. Middleton (11448392), Joan Teyra (16828), Jingyi Zhu (1282827), Sachdev S. Sidhu (141559), Catherine L. Day (366428)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, potentially disrupting interactions, crystal structures reveal, ubiquitin signal generated, substrate proteins regulates, ubiquitin activating enzyme, catalyzed ubiquitin transfer, called ubiquitin variants, substrate proteins, ubiquitin variants, data reveal, ubiquitin machinery, ubiquitin charging, ube2k transfer, e2 enzyme, ultimate fate, potent inhibitors, identified protein, hydrophobic groove

Relation: https://figshare.com/articles/journal_contribution/Identification_of_Ubiquitin_Variants_That_Inhibit_the_E2_Ubiquitin_Conjugating_Enzyme_Ube2k/16635005

الاتاحة: https://doi.org/10.1021/acschembio.1c00445.s001

المؤلفون: Meiklejohn, H, Mostaid, MS, Luza, S, Mancuso, SG, Kang, D, Atherton, S, Rothmond, DA, Weickert, CS, Opazo, CM, Pantelis, C, Bush, AI, Everall, IP, Bousman, CA

المصدر: urn:ISSN:0022-3956 ; urn:ISSN:1879-1379 ; Journal of Psychiatric Research, 113, 51-57

مصطلحات موضوعية: Mental Health, Brain Disorders, Neurosciences, Schizophrenia, Serious Mental Illness, 2.1 Biological and endogenous factors, 2 Aetiology, Adult, Australia, Brain, Female, Humans, Male, Middle Aged, Ubiquitin-Conjugating Enzymes, Gene expression, Post-mortem, Protein expression, Treatment-resistant, UBE2K, Ubiquitin, anzsrc-for: 11 Medical and Health Sciences, anzsrc-for: 17 Psychology and Cognitive Sciences

Relation: http://hdl.handle.net/1959.4/unsworks_57489; https://doi.org/10.1016/j.jpsychires.2019.03.005

الاتاحة: http://hdl.handle.net/1959.4/unsworks_57489
https://doi.org/10.1016/j.jpsychires.2019.03.005

المؤلفون: RICARDO RAJSBAUM, GIJS A. VERSTEEG, SONJA SCHMID, ANA M. MAESTRE, ALAN BELICHA VILLANUEVA, CARLES MARTÍNEZ ROMERO, JENISH R. PATEL, JULIET MORRISON, LISA MIORIN, MAUDRY LAURENT ROLLE, HONG M. MOULTON, DAVID A. STEIN, ANA FERNANDEZ SESMA, BENJAMIN R. TENOEVER, ADOLFO GARCÍA S.A.S.T.R.E., PISANELLI, GIUSEPPE

المساهمون: Ricardo, Rajsbaum, GIJS A., Versteeg, Sonja, Schmid, ANA M., Maestre, ALAN BELICHA, Villanueva, CARLES MARTÍNEZ, Romero, JENISH R., Patel, Juliet, Morrison, Pisanelli, Giuseppe, Lisa, Miorin, MAUDRY LAURENT, Rolle, HONG M., Moulton, DAVID A., Stein, ANA FERNANDEZ, Sesma, BENJAMIN R., Tenoever, ADOLFO GARCÍA, S. A. S. T. R. E.

مصطلحات موضوعية: TRIM6 plays a critical role in innate immune activation, TRIM6 and the E2 conjugase UbE2K synthesize unanchored K48-linked ubiquitin chain, Unanchored K48-linked ubiquitin chains activate the IKKε kinase, TRIM6 couples IFNαR engagement to activation of the IKKε kinase for ISG induction

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000341440200011; volume:40; issue:6; firstpage:880; lastpage:895; numberofpages:16; journal:IMMUNITY; http://hdl.handle.net/11588/582201; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84903647409; http://www.sciencedirect.com/science/article/pii/S1074761314001800

الاتاحة: http://hdl.handle.net/11588/582201
https://doi.org/10.1016/j.immuni.2014.04.018
http://www.sciencedirect.com/science/article/pii/S1074761314001800

المؤلفون: Cao, Cong, Rioult-Pedotti, Mengia S, Migani, Paolo, Yu, Crystal J, Tiwari, Rakesh, Parang, Keykavous, Spaller, Mark R

المصدر: Dartmouth Scholarship

مصطلحات موضوعية: ube3a, mapk1, gab1, bdnf, dlg4, arc, grb2, plcg1, ntrk2, camk2a, ube2k, ephb2, angelman syndrome, autistic disorder, synapses, post-synaptic density, hippocampus, calcium-calmodulin-dependent protein kinases, proteins, ligands, extracellular signal-regulated map kinases, receptor, trkb, ubiquitin-protein ligases, calcium-calmodulin-dependent protein kinase type 2, peptides, cyclic, cytoskeletal proteins, brain-derived neurotrophic factor, map kinase signaling system

وصف الملف: application/pdf

Relation: https://digitalcommons.dartmouth.edu/facoa/1570; https://digitalcommons.dartmouth.edu/context/facoa/article/2573/viewcontent/ptpmcrender.fcgi

الاتاحة: https://digitalcommons.dartmouth.edu/facoa/1570
https://doi.org/10.1371/journal.pbio.1001478
https://digitalcommons.dartmouth.edu/context/facoa/article/2573/viewcontent/ptpmcrender.fcgi

المؤلفون: McAuley, Jacob, Harding, Rachel, Arrowsmith, Cheryl, Edwards, Aled

مصطلحات موضوعية: UBE2K, Huntingtin Interactome, SGC

Relation: https://zenodo.org/communities/jacobmcauley_summer2019; https://doi.org/10.5281/zenodo.3267175; https://doi.org/10.5281/zenodo.3267176; oai:zenodo.org:3267176

الاتاحة: https://doi.org/10.5281/zenodo.3267176

المؤلفون: Doorman, Josiah

المساهمون: Day, Catherine

مصطلحات موضوعية: Ube2K, Ubiquitin, K48, K63, Degradation

Relation: http://hdl.handle.net/10523/9574

الاتاحة: http://hdl.handle.net/10523/9574

المؤلفون: Fokkens, Thornton J.

المساهمون: Day, Catherine L.

مصطلحات موضوعية: RNF125, Ubiquitin, Ube2K, Cell signalling, Protein biochemistry

Relation: http://hdl.handle.net/10523/9036

الاتاحة: http://hdl.handle.net/10523/9036

المؤلفون: Djajawi, Tirta

مصطلحات موضوعية: cancer, cell death, apoptosis, BCL2, MCL1, NOXA, BIM, MARCH5, MTCH2, UBE2K, Ubiquitin Proteasome System (UPS), Proteasomal degradation, E3 ligase, Deubiquitinating enzyme, BH3 mimetics, BH3 profiling

Relation: http://hdl.handle.net/11343/237464

الاتاحة: http://hdl.handle.net/11343/237464

المؤلفون: Freitas S., Martins R., Campos A., Azevedo J., Osório H., Costa M., Barros P., Vasconcelos V., Urbatzka R.

مصطلحات موضوعية: acetic acid ethyl ester, algal extract, Cyanobium extract, cytotoxic agent, messenger RNA, protein bcl 2, Synechocystis salina extract, unclassified drug, AHSG gene, apoptosis, Article, ATP5H gene, bacterial strain, BCL 2 gene, cancer cell line, cancer therapy, CCNB1 gene, cell cycle, cell cycle arrest, cell cycle G0 phase, cell cycle G1 phase, cell cycle M phase, cell cycle S phase, cell metabolism, cell structure, colon adenocarcinoma, colon adenocarcinoma cell line, controlled study, cyanobacterium, Cyanobium, cytotoxicity test, drug cytotoxicity, EIF4E gene, epifluorescence microscopy, flow cytometry, fluorescence microscopy, G2 phase cell cycle checkpoint, gene, gene expression, GLO1 gene, HNRNPC gene, HSP90AB1 gene, HSPD1 gene, human, human cell, IC50, KRT1 gene, KRT10 gene, NME1 gene, nonhuman, PCNA gene, priority journal, protein metabolism, proteomics, PSMA5 gene, PSMA7 gene, qualitative analysis, quantitative analysis, Synechocystis salina, TPT1 gene, UBE2K gene

وصف الملف: application/pdf

Relation: 00410101

الاتاحة: https://hdl.handle.net/10216/120340

المؤلفون: Margarida Costa, Vitor Vasconcelos, Rosário Martins, Ralph Urbatzka, Hugo Osório, Sara Freitas, Piedade Barros, Alexandre Campos, Joana Azevedo

المساهمون: CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental, Repositório Científico do Instituto Politécnico do Porto

المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Toxicon

مصطلحات موضوعية: 0301 basic medicine, Proteomics, epifluorescence microscopy, Cell cycle checkpoint, Cyanobium, Apoptosis, IC50, Toxicology, Synechocystis salina extract, fluorescence microscopy, cell cycle M phase, 0302 clinical medicine, cell metabolism, Cytotoxic T cell, Cytotoxicity, G2 phase cell cycle checkpoint, acetic acid ethyl ester, GLO1 gene, PSMA7 gene, medicine.diagnostic_test, quantitative analysis, messenger RNA, CCNB1 gene, drug cytotoxicity, apoptosis, Tumor Protein, Translationally-Controlled 1, HSP90AB1 gene, Cell cycle, Plankton, unclassified drug, PSMA5 gene, priority journal, cell cycle arrest, protein metabolism, 030220 oncology & carcinogenesis, cytotoxic agent, cancer therapy, cell cycle, cancer cell line, protein bcl 2, cell cycle G0 phase, HSPD1 gene, Picocyanobacteria, NME1 gene, Marine Biology, Biology, Cyanobacteria, Article, Flow cytometry, 03 medical and health sciences, Cyanobium extract, proteomics, cyanobacterium, Cell Line, Tumor, medicine, Humans, qualitative analysis, AHSG gene, controlled study, 14. Life underwater, Anticancer potential, human, algal extract, BCL 2 gene, gene, HNRNPC gene, ATP5H gene, colon adenocarcinoma cell line, cell cycle G1 phase, nonhuman, flow cytometry, human cell, KRT10 gene, bacterial strain, Molecular biology, Synechocystis salina, PCNA gene, TPT1 gene, 030104 developmental biology, cell cycle S phase, colon adenocarcinoma, Cell culture, KRT1 gene, Cancer cell, gene expression, UBE2K gene, EIF4E gene, cytotoxicity test, cell structure

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1fc2273633717c35fcfafb5bddabb2