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1Academic Journal
المؤلفون: Song, Aixin, Hazlett, Zachary, Abeykoon, Dulith, Dortch, Jeremy, Dillon, Andrew, Curtiss, Justin, Martinez, Sarah Bollinger, Hill, Christopher P, Yu, Clinton, Huang, Lan, Fushman, David, Cohen, Robert E, Yao, Tingting
مصطلحات موضوعية: Generic health relevance, Catalytic Domain, Gene Deletion, HCT116 Cells, HEK293 Cells, Humans, Inclusion Bodies, Intracellular Signaling Peptides and Proteins, Proteasome Endopeptidase Complex, Protein Binding, Proteolysis, Ubiquitin, UCH37, UCHL5, ubiquitin, DUB, branched ubiquitin chain, proteasome, Human, biochemistry, cell biology, chemical biology, human, Biochemistry and Cell Biology
وصف الملف: application/pdf
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2Academic Journal
المؤلفون: Pispa, Johanna, Mikkonen, Elisa, Arpalahti, Leena, Jin, Congyu, Martinez-Fernandez, Carmen, Ceron, Julian, Holmberg, Carina I.
المساهمون: Department of Biochemistry and Developmental Biology, Medicum, Department of Anatomy
مصطلحات موضوعية: Deubiquitinating enzyme, Protein-degradation, Nuclear import, Ubiquitin, Drosophila, Localization, Destruction, Uch37, Biomedicine, Biochemistry, cell and molecular biology
وصف الملف: application/pdf
Relation: Pispa , J , Mikkonen , E , Arpalahti , L , Jin , C , Martinez-Fernandez , C , Ceron , J & Holmberg , C I 2023 , ' AKIR-1 regulates proteasome subcellular function in Caenorhabditis elegans ' , iScience , vol. 26 , no. 10 , 107886 . https://doi.org/10.1016/j.isci.2023.107886; ORCID: /0000-0003-0002-5235/work/146908840; ORCID: /0000-0002-7460-868X/work/146909413; http://hdl.handle.net/10138/567147; 5e39ecec-def6-4289-bbfc-ccdf0ab7af85; 001083201700001
الاتاحة: http://hdl.handle.net/10138/567147
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3Academic Journal
المؤلفون: Babik, Sandor
المصدر: Doctoral Dissertations
مصطلحات موضوعية: Ubiquitin, UCH37, UCHL5, Biochemistry
وصف الملف: application/pdf
Relation: https://scholarworks.umass.edu/dissertations_2/2593; https://scholarworks.umass.edu/context/dissertations_2/article/3804/viewcontent/SB_Thesis_update03.pdf
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4Academic Journal
المؤلفون: Bisbee, Heather A
المصدر: Doctoral Dissertations
مصطلحات موضوعية: UCH37, ubiquitin, degradation, proteasome, INO80, cell cycle, Cell Biology, Molecular Biology
وصف الملف: application/pdf
Relation: https://scholarworks.umass.edu/dissertations_2/2597; https://scholarworks.umass.edu/context/dissertations_2/article/3728/viewcontent/Bisbee.pdf
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5Academic Journal
المؤلفون: Aixin Song, Zachary Hazlett, Dulith Abeykoon, Jeremy Dortch, Andrew Dillon, Justin Curtiss, Sarah Bollinger Martinez, Christopher P Hill, Clinton Yu, Lan Huang, David Fushman, Robert E Cohen, Tingting Yao
المصدر: eLife, Vol 10 (2021)
مصطلحات موضوعية: UCH37, UCHL5, ubiquitin, DUB, branched ubiquitin chain, proteasome, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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6Academic Journal
المؤلفون: Seonghyeon Moon, Srinivasan Muniyappan, Sung-Bae Lee, Byung-Hoon Lee
المصدر: International Journal of Molecular Sciences; Volume 22; Issue 12; Pages: 6213
مصطلحات موضوعية: proteasome, proteolysis, deubiquitinase, USP14, UCH37, RPN11, small-molecule inhibitors, IU1, capzimin
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Biochemistry; https://dx.doi.org/10.3390/ijms22126213
الاتاحة: https://doi.org/10.3390/ijms22126213
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7Academic Journal
المؤلفون: Hazlett, Zachary S., author, Yao, Tingting, advisor, Cohen, Robert, committee member, Peersen, Olve, committee member, Di Pietro, Santiago, committee member, Kennan, Alan, committee member
مصطلحات موضوعية: proteasome, branched ubiquitin, Uch37
وصف الملف: born digital; masters theses; application/pdf
Relation: 2020-; Hazlett_colostate_0053N_16389.pdf; https://hdl.handle.net/10217/219567
الاتاحة: https://hdl.handle.net/10217/219567
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8Academic Journal
المؤلفون: Jang, Seok Hoon, Park, Jun Won, Kim, Hyo Rim, Seong, Je Kyung, Kim, Hark Kyun
المساهمون: Seong, Je Kyung
مصطلحات موضوعية: DEUBIQUITINATING ENZYME, PROTEASOME SUBUNIT, UBIQUITIN RECEPTOR, COLORECTAL-CANCER, UCH37, ACTIVATION, EXPRESSION, ADRM1, Gastric, Cancer, Metastatic, Amplification
Relation: Clinical and Experimental Metastasis, Vol.31 No.6, pp.727-733; https://hdl.handle.net/10371/207390; 000340587800011; 2-s2.0-84906789818; 118677
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9Academic Journal
المؤلفون: Ji Yeong Shin, Srinivasan Muniyappan, Non-Nuoc Tran, Hyeonjeong Park, Sung Bae Lee, Byung-Hoon Lee
المصدر: International Journal of Molecular Sciences; Volume 21; Issue 15; Pages: 5312
مصطلحات موضوعية: proteasome, proteolysis, ubiquitin, deubiquitination, deubiquitinating enzyme, USP14, UCH37, RPN11
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Biochemistry; https://dx.doi.org/10.3390/ijms21155312
الاتاحة: https://doi.org/10.3390/ijms21155312
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10Academic Journal
المؤلفون: Arpalahti, Leena, Laitinen, Alli, Hagström, Jaana, Mustonen, Harri, Kokkola, Arto, Böckelman, Camilla, Haglund, Caj, Holmberg, Carina I.
المساهمون: Translational Cancer Biology (TCB) Research Programme, Research Programs Unit, University of Helsinki, Medicum, Clinicum, Department of Pathology, HUSLAB, Department of Surgery, II kirurgian klinikka, HUS Head and Neck Center, HUS Abdominal Center
مصطلحات موضوعية: UBIQUITIN-PROTEASOME SYSTEM, MULTIPLE-MYELOMA, INHIBITION, BORTEZOMIB, RESISTANCE, ACTIVATION, APOPTOSIS, STRATEGY, UCH37, Cancers, Surgery, anesthesiology, intensive care, radiology
وصف الملف: application/pdf
Relation: This work was supported by Mediciniska Understodsforenigen Liv och Halsa r.f., The Ruth and Nils-Erik Stenback Foundation (C.H.); K.Albin Johansson Foundation (L.A.); The Kurt och Doris Palander Foundation, The Martti I. Turunen Foundation (A.L.).; Arpalahti , L , Laitinen , A , Hagström , J , Mustonen , H , Kokkola , A , Böckelman , C , Haglund , C & Holmberg , C I 2018 , ' Positive cytoplasmic UCHL5 tumor expression in gastric cancer is linked to improved prognosis ' , PLoS One , vol. 13 , no. 2 , 0193125 . https://doi.org/10.1371/journal.pone.0193125; ORCID: /0000-0001-6079-7881/work/49700320; ORCID: /0000-0001-5632-6796/work/43227749; http://hdl.handle.net/10138/233837; 9f36d4ef-cca8-4bb1-aa2f-f1c6d2ec6c44; 85042527409; 000426049500056
الاتاحة: http://hdl.handle.net/10138/233837
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11Academic Journal
المؤلفون: Arpalahti, Leena, Hagstrom, Jaana, Mustonen, Harri, Lundin, Mikael, Haglund, Caj, Holmberg, Carina I.
المساهمون: Research Programs Unit, Translational Cancer Biology (TCB) Research Programme, University of Helsinki, Medicum, Clinicum, Department of Pathology, HUSLAB, Department of Surgery, II kirurgian klinikka, Institute for Molecular Medicine Finland, Johan Edvard Lundin / Principal Investigator, HUS Head and Neck Center, HUS Abdominal Center
مصطلحات موضوعية: Colorectal cancer, deubiquitination, prognosis, proteasome, UCHL5, DEUBIQUITINATING ENZYME UCH37, SMALL-MOLECULE INHIBITOR, PROTEASOME ACTIVITY, ACTIVATION, RESISTANCE, STRATEGY, USP14, Cancers
وصف الملف: application/pdf
Relation: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by grants to C.I.H. from the Academy of Finland (259797 and 297776), Medicinska Understodsforeningen Liv och Halsa r.f., and Ruth and Nils-Erik Stenback Foundation and to C.H. from the Sigrid Jusulius Foundation and the Cancer Society of Finland. L.A. was supported by the Doctoral Programme in Biomedicine of University of Helsinki and by grants from the Victoria Foundation and the K. Albin Johansson Foundation.; Arpalahti , L , Hagstrom , J , Mustonen , H , Lundin , M , Haglund , C & Holmberg , C I 2017 , ' UCHL5 expression associates with improved survival in lymph-node-positive rectal cancer ' , Tumor Biology , vol. 39 , no. 7 . https://doi.org/10.1177/1010428317716078; ORCID: /0000-0001-6079-7881/work/49700369; ORCID: /0000-0001-5632-6796/work/38515319; http://hdl.handle.net/10138/222497; d9ea2db7-b4ff-48c0-b1fd-578ba97f925f; 85026293562; 000407141700001
الاتاحة: http://hdl.handle.net/10138/222497
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12Academic Journal
المؤلفون: Arpalahti, Leena, Saukkonen, Kapo, Hagström, Jaana, Mustonen, Harri, Seppänen, Hanna, Haglund, Caj, Holmberg, Carina I.
المساهمون: Research Programs Unit, Translational Cancer Biology (TCB) Research Programme, University of Helsinki, Department of Surgery, HUS Abdominal Center, HUS Head and Neck Center, Medicum, Clinicum, Department of Pathology, HUSLAB, II kirurgian klinikka
مصطلحات موضوعية: Deubiquitination, pancreatic ductal adenocarcinoma, prognosis, proteasome, ubiquitin C-terminal hydrolase L5, UCHL5, PROTEASOME INHIBITORS, MULTIPLE-MYELOMA, CELL-MIGRATION, CANCER, BORTEZOMIB, SYSTEM, UCH37, DEUBIQUITINASES, ACTIVATION, BIOMARKERS, Cancers
وصف الملف: application/pdf
Relation: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by grants to C.I.H. from the Academy of Finland (259797, 297776), Medicinska Understodsforeningen Liv och Halsa r.f., and the Ruth and Nils-Erik Stenback Foundation, to C.H. from the Sigrid Juselius Foundation and the Cancer Society of Finland, and to H.S. from the Mary and Georg C Ehrnrooth Foundation, the Sigrid Juselius Foundation, and the Helsinki University Hospital Research Fund. L.A. was supported by the Doctoral Programme in Biomedicine, University of Helsinki and by grants from the Victoria Foundation and the K. Albin Johansson Foundation. K.S. was supported by grants from the K. Albin Johansson Foundation and from the Ida Montin Foundation.; Arpalahti , L , Saukkonen , K , Hagström , J , Mustonen , H , Seppänen , H , Haglund , C & Holmberg , C I 2017 , ' Nuclear ubiquitin C-terminal hydrolase L5 expression associates with increased patient survival in pancreatic ductal adenocarcinoma ' , Tumor Biology , vol. 39 , no. 6 . https://doi.org/10.1177/1010428317710411; ORCID: /0000-0001-6079-7881/work/49700362; ORCID: /0000-0001-5632-6796/work/38515298; ORCID: /0000-0002-2529-651X/work/156151786; http://hdl.handle.net/10138/222488; b0d3fc39-7050-4fa2-ade3-a21e469786d2; 85024102556; 000404542700001
الاتاحة: http://hdl.handle.net/10138/222488
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13Academic Journal
المؤلفون: HAN, JIN KWAN
المساهمون: HAN, JIN KWAN
مصطلحات موضوعية: UCH37 DEUBIQUITINATING ENZYME, DIX DOMAIN, WNT, DEGRADATION, INHIBITION, PROTEASOME
Relation: Scientific Reports; Multidisciplinary Sciences; Science & Technology - Other Topics; https://oasis.postech.ac.kr/handle/2014.oak/115933; 52942; Scientific Reports, v.12, no.1; 000765922600047; 2-s2.0-85125977100
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14
المؤلفون: Christopher P. Hill, Dulith Abeykoon, Clinton Yu, Andrew Dillon, Robert E. Cohen, Tingting Yao, David Fushman, Jeremy Dortch, Zachary Hazlett, Lan Huang, Justin Curtiss, Sarah Bollinger Martinez, Aixin Song
المصدر: eLife
eLife, Vol 10 (2021)مصطلحات موضوعية: UCHL5, Proteasome Endopeptidase Complex, RAD23B, QH301-705.5, Science, Chemical biology, chemical biology, DUB, UCH37, General Biochemistry, Genetics and Molecular Biology, Deubiquitinating enzyme, Ubiquitin, Biochemistry and Chemical Biology, Catalytic Domain, cell biology, biochemistry, Humans, human, Biology (General), Inclusion Bodies, General Immunology and Microbiology, biology, Chemistry, General Neuroscience, Intracellular Signaling Peptides and Proteins, Active site, Substrate (chemistry), Cell Biology, General Medicine, branched ubiquitin chain, HCT116 Cells, Cell biology, Ubiquitins, proteasome, HEK293 Cells, Proteasome, Proteolysis, biology.protein, Medicine, Generic health relevance, Biochemistry and Cell Biology, Gene Deletion, Research Article, Human, Protein Binding, Deubiquitination
وصف الملف: application/pdf
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15Academic Journal
المؤلفون: Vincent, Seenya
المصدر: Dissertations and Theses (Open Access)
مصطلحات موضوعية: UCHL5, UCH37, melanoma, metastasis, epigenome, immunotherapy, Medicine and Health Sciences
وصف الملف: application/pdf
Relation: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/1140; https://digitalcommons.library.tmc.edu/context/utgsbs_dissertations/article/2196/viewcontent/auto_convert.pdf
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16Dissertation/ Thesis
المؤلفون: Panov, Alexandra
المساهمون: Harper, J. Wade, Finley, Daniel, Denic, Vladimir, Feany, Mel, Raman, Malavika
مصطلحات موضوعية: hul5, proteasome, RPN13, UBE3C, Uch37, UCHL5, Biology, Molecular biology
وصف الملف: application/pdf
Relation: Panov, Alexandra. 2024. The roles of proteasome-associated factors RPN13, UCHL5, and UBE3C in basal, unfolded, and aggregated protein turnover. Doctoral dissertation, Harvard University Graduate School of Arts and Sciences.; https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37378991; orcid:0000-0002-2960-0291
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17
المؤلفون: Alexey V. Antonov, Andrey Lisitsa, Ivano Amelio, Richard A. Knight, Gerry Melino, Vivien Landré
المصدر: Oncotarget
Europe PubMed Centralمصطلحات موضوعية: Proteasome Endopeptidase Complex, Databases, Factual, Polypharmacology, SUMO-1 Protein, Drug efficiency, Review, Computational biology, UPS, Biology, Bioinformatics, UCH37, Mice, UBL, Ubiquitin, ddc:570, Neoplasms, Protein Interaction Mapping, Animals, Humans, Settore BIO/10, Therapeutic strategy, Ubiquitin proteasome, Drug discovery, Ubiquitination, Medical research, Small molecule, Cysteine Endopeptidases, Oncology, SUMO, UBC13, Drug Design, Ubiquitin-Conjugating Enzymes, biology.protein, Ubiquitin Thiolesterase, Signal Transduction
وصف الملف: application/pdf
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18Academic Journal
المؤلفون: Caj Haglund, Arto Kokkola, Leena Arpalahti, Harri Mustonen, Carina I. Holmberg, Camilla Böckelman, Jaana Hagström, Alli Laitinen
المساهمون: University of Helsinki, Translational Cancer Biology (TCB) Research Programme, University of Helsinki, Medicum, University of Helsinki, Clinicum, University of Helsinki, II kirurgian klinikka, University of Helsinki, Research Programs Unit
المصدر: oai:helda.helsinki.fi:10138/233837 ; 10.1371/journal.pone.0193125 ; 2793930761 ; oai:doaj.org/article:ffb5bb144c9142f49f2261bbecaa9a6f ; oai:pubmedcentral.nih.gov:5825037 ; 29718984 ; 10|opendoar____::06a81a4fb98d149f2d31c68828fa6eb2 ; 10|openaire____::081b82f96300b6a6e3d282bad31cb6e2 ; 10|doajarticles::830e55b42c4aaa815c19cfa4f2e5855e ; 10|openaire____::8ac8380272269217cb09a928c8caa993 ; 10|openaire____::5f532a3fc4f1ea403f37070f59a7a53a ; 10|openaire____::9e3be59865b2c1c335d32dae2fe7b254 ; 10|openaire____::55045bd2a65019fd8e6741a755395c8c ; 10|driver______::bee53aa31dc2cbb538c10c2b65fa5824 ; 10|opendoar____::eda80a3d5b344bc40f3bc04f65b7a357 ; 10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c ; openaire____::1256f046-bf1f-4afc-8b47-d0b147148b18 ; 10|openaire____::806360c771262b4d6770e7cdf04b5c5a
مصطلحات موضوعية: UBIQUITIN-PROTEASOME SYSTEM, MULTIPLE-MYELOMA, INHIBITION, BORTEZOMIB, RESISTANCE, ACTIVATION, APOPTOSIS, STRATEGY, UCH37, 3122 Cancers, 3126 Surgery, anesthesiology, intensive care, radiology, General Biochemistry, Genetics and Molecular Biology, General Agricultural and Biological Sciences, General Medicine, Research Article, Medicine and Health Sciences, Cancers and Neoplasms, Gastrointestinal Tumors, Gastric Cancer, Surgical and Invasive Medical Procedures, Biology and Life Sciences, Biochemistry, Proteins, Protein Complexes, Proteasomes, Diagnostic Medicine
Relation: http://hdl.handle.net/10138/233837; http://dx.plos.org/10.1371/journal.pone.0193125; http://dx.doi.org/10.1371/journal.pone.0193125; https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0193125&type=printable; https://www.ncbi.nlm.nih.gov/pubmed/29474458; https://pubmed.ncbi.nlm.nih.gov/29474458/; https://ui.adsabs.harvard.edu/abs/2018PLoSO.1393125A/abstract; https://researchportal.helsinki.fi/fi/publications/positive-cytoplasmic-uchl5-tumor-expression-in-gastric-cancer-is-; https://helda.helsinki.fi/handle/10138/233837; https://dx.plos.org/10.1371/journal.pone.0193125; https://core.ac.uk/display/157587529; https://academic.microsoft.com/#/detail/2793930761; https://dx.doi.org/10.1371/journal.pone.0193125; http://europepmc.org/articles/PMC5825037?pdf=render; http://europepmc.org/articles/PMC5825037
الاتاحة: http://hdl.handle.net/10138/233837
https://doi.org/10.1371/journal.pone.0193125
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0193125&type=printable
https://www.ncbi.nlm.nih.gov/pubmed/29474458
https://pubmed.ncbi.nlm.nih.gov/29474458/
https://ui.adsabs.harvard.edu/abs/2018PLoSO.1393125A/abstract
https://researchportal.helsinki.fi/fi/publications/positive-cytoplasmic-uchl5-tumor-expression-in-gastric-cancer-is-
https://helda.helsinki.fi/handle/10138/233837
https://core.ac.uk/display/157587529
https://academic.microsoft.com/#/detail/2793930761 -
19
المؤلفون: Jaana Hagström, Alli Laitinen, Camilla Böckelman, Caj Haglund, Leena Arpalahti, Arto Kokkola, Harri Mustonen, Carina I. Holmberg
المساهمون: Translational Cancer Biology (TCB) Research Programme, Research Programs Unit, University of Helsinki, Medicum, Clinicum, Department of Pathology, HUSLAB, Department of Surgery, II kirurgian klinikka, HUS Head and Neck Center, HUS Abdominal Center
المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0193125 (2018)مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cytoplasm, Colorectal cancer, lcsh:Medicine, UCH37, ACTIVATION, Surgical oncology, lcsh:Science, Multiple myeloma, Multidisciplinary, Middle Aged, 3. Good health, APOPTOSIS, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Survival Rate, Hepatocellular carcinoma, Immunohistochemistry, Female, Ubiquitin Thiolesterase, medicine.medical_specialty, 3122 Cancers, INHIBITION, BORTEZOMIB, UBIQUITIN-PROTEASOME SYSTEM, Disease-Free Survival, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, Stomach Neoplasms, Internal medicine, Pancreatic cancer, MULTIPLE-MYELOMA, medicine, Biomarkers, Tumor, Humans, STRATEGY, Survival rate, Aged, business.industry, lcsh:R, Cancer, Correction, medicine.disease, 3126 Surgery, anesthesiology, intensive care, radiology, 030104 developmental biology, lcsh:Q, business, RESISTANCE
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20
المؤلفون: Harri Mustonen, Caj Haglund, Jaana Hagström, Leena Arpalahti, Mikael Lundin, Carina I. Holmberg
المساهمون: Research Programs Unit, Translational Cancer Biology (TCB) Research Programme, University of Helsinki, Medicum, Clinicum, Department of Pathology, HUSLAB, Department of Surgery, II kirurgian klinikka, Institute for Molecular Medicine Finland, Johan Edvard Lundin / Principal Investigator, HUS Head and Neck Center, HUS Abdominal Center
المصدر: Tumor Biology, Vol 39 (2017)
مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, UCHL5, medicine.medical_specialty, Lymph node positive, Colorectal cancer, 3122 Cancers, Improved survival, Biology, Disease-Free Survival, ACTIVATION, 03 medical and health sciences, Internal medicine, medicine, Biomarkers, Tumor, PROTEASOME ACTIVITY, Humans, STRATEGY, Stage (cooking), deubiquitination, RC254-282, Aged, Neoplasm Staging, SMALL-MOLECULE INHIBITOR, Incidence (epidemiology), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cancer, DEUBIQUITINATING ENZYME UCH37, General Medicine, Middle Aged, medicine.disease, Prognosis, USP14, 3. Good health, Gene Expression Regulation, Neoplastic, proteasome, 030104 developmental biology, Lymphatic Metastasis, Cohort, Immunology, Immunohistochemistry, Female, Lymph Nodes, Colorectal Neoplasms, Ubiquitin Thiolesterase, RESISTANCE