المؤلفون: Le P. Ngo, Tze Khee Chan, Jing Ge, Leona D. Samson, Bevin P. Engelward

المصدر: Cell Reports, Vol 26, Iss 6, Pp 1668-1678.e4 (2019)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124719300828; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/307bec8b38724df1bd71225c2dcd8bfe

المؤلفون: Andrew Aswani, Joanna Manson, Kiyoshi Itagaki, Fausto Chiazza, Massimo Collino, Winston Liao Wupeng, Tze Khee Chan, W. S. Fred Wong, Carl J. Hauser, Chris Thiemermann, Karim Brohi

المصدر: Frontiers in Immunology, Vol 9 (2018)

مصطلحات موضوعية: trauma, mitochondrial DNA, damage-associated molecular patterns, nucleic acid scavenger, multiple organ dysfunction syndrome, trauma hemorrhage, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2018.00891/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/f33152db51364c239125d0807f5f3b30

المؤلفون: Siew Tein Wang, Namita Misra, Tze Khee Chan, Nasrine Bourokba, Rebecca Y.X. Lim, Boon Hoe Neo, Richard J. Betts, Vedula Krishna, Hyoju Kim, Diah Bramono, Shawn Lim

المصدر: Journal of dermatological science. 104(2)

مصطلحات موضوعية: Keratinocytes, Chemokine, Pro-Opiomelanocortin, DNA Repair, DNA damage, Anti-Inflammatory Agents, Skin Pigmentation, Dermatology, Ascorbic Acid, Biochemistry, Antioxidants, Dexamethasone, Proinflammatory cytokine, Melanin, chemistry.chemical_compound, Immune System Phenomena, Interferon-gamma, Skin Pigmentation Disorder, Proopiomelanocortin, Isothiocyanates, Benzo(a)pyrene, Humans, Vitamin E, Polycyclic Aromatic Hydrocarbons, Molecular Biology, Cells, Cultured, Melanins, biology, Tumor Necrosis Factor-alpha, Interleukin-8, Aryl hydrocarbon receptor, Molecular biology, Coculture Techniques, chemistry, Receptors, Aryl Hydrocarbon, Culture Media, Conditioned, Sulfoxides, biology.protein, Leukocytes, Mononuclear, Cytokines, Epidermis, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb40163aa3608ccdf945b088b400d43c
https://pubmed.ncbi.nlm.nih.gov/34690024

المؤلفون: W.S. Daniel Tan, Amy Yong, W.S. Fred Wong, Li Li, Jinrui Dong, Tze Khee Chan, Wupeng Liao, Hong Yong Peh

المصدر: British Journal of Pharmacology. 174:540-552

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, House dust mite, Gene knockdown, Small interfering RNA, Reporter gene, biology, medicine.medical_treatment, respiratory system, Eosinophil, biology.organism_classification, respiratory tract diseases, 03 medical and health sciences, 030104 developmental biology, Cytokine, medicine.anatomical_structure, Immunology, Cancer research, medicine, Gene silencing, Eukaryotic Small Ribosomal Subunit

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8ceaa8f014a20190b4b1b079669d9d43
https://doi.org/10.1111/bph.13717

المؤلفون: W.S. Daniel Tan, W.S. Fred Wong, Wupeng Liao, Vincent T. K. Chow, Tze Khee Chan, Suk Hiang Lau, Hong Yong Peh, Chu Hui Pang

المصدر: Journal of Natural Products. 79:1308-1315

مصطلحات موضوعية: 0301 basic medicine, Haemophilus Infections, Neutrophils, Glutamate-Cysteine Ligase, medicine.medical_treatment, Andrographolide, Glutathione reductase, Pharmaceutical Science, Inflammation, Analytical Chemistry, Mice, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, chemistry.chemical_compound, Tobacco, Drug Discovery, medicine, Animals, Humans, Pharmacology, Mice, Inbred BALB C, COPD, Plants, Medicinal, Molecular Structure, Tumor Necrosis Factor-alpha, GCLM, business.industry, Smoking, Organic Chemistry, Pneumonia, medicine.disease, Haemophilus influenzae, Mice, Inbred C57BL, CXCL1, Matrix Metalloproteinase 8, 030104 developmental biology, Cytokine, Neutrophil Infiltration, Complementary and alternative medicine, chemistry, Immunology, Molecular Medicine, Andrographis, Female, Tumor necrosis factor alpha, Diterpenes, medicine.symptom, business, Heme Oxygenase-1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226b50734414430964148314cf20903b
https://doi.org/10.1021/acs.jnatprod.5b01006

المؤلفون: Les Recio, Yang Su, Matthew R. Wilson, Prashant Rai, Carole Swartz, John Winters, Bevin P. Engelward, Vincent T. K. Chow, Leona D. Samson, Tze-Khee Chan, Emily P. Balskus, Jing Ge, Le P. Ngo

المصدر: Cancer Prevention Research. 13:IA20-IA20

مصطلحات موضوعية: Cancer Research, DNA damage, Chemistry, Cell, DNA replication, medicine.disease_cause, Molecular biology, Comet assay, chemistry.chemical_compound, medicine.anatomical_structure, Oncology, medicine, Cytotoxicity, DNA, Genotoxicity, Nucleotide excision repair

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aa536121940907995d99699f71868eb3
https://doi.org/10.1158/1940-6215.envcaprev19-ia20

المؤلفون: W.S. Fred Wong, Ann Ching Genevieve Seow, Chang Cheng, Albert Yick Hou Lim, Hong Yong Peh, Choon Nam Ong, Tze Khee Chan, Wanxing Eugene Ho, Chee Wai Fong, Kok Yong Seng

المصدر: The Journal of Immunology. 195:437-444

مصطلحات موضوعية: Neutrophils, Dermatophagoides pteronyssinus, medicine.medical_treatment, alpha-Tocopherol, Anti-Inflammatory Agents, Gene Expression, Immunoglobulin E, medicine.disease_cause, Antioxidants, Mice, chemistry.chemical_compound, Vitamin E, Immunology and Allergy, Lung, Methacholine Chloride, Mice, Inbred BALB C, biology, medicine.diagnostic_test, NF-kappa B, respiratory system, medicine.anatomical_structure, Cytokines, Female, Tocotrienol, Bronchoalveolar Lavage Fluid, NF-E2-Related Factor 2, Prednisolone, Immunology, Proinflammatory cytokine, medicine, Animals, Chromans, House dust mite, business.industry, Allergens, Eosinophil, biology.organism_classification, Asthma, respiratory tract diseases, Eosinophils, Disease Models, Animal, Oxidative Stress, Bronchoalveolar lavage, chemistry, biology.protein, Reactive Oxygen Species, business, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1f830a20286d6c860630a3bc9906f9
https://doi.org/10.4049/jimmunol.1500362

المؤلفون: Orsolya Kiraly, Na Li, Marcus C. Parrish, Tze Khee Chan, Nona Abolhassani, Yamada Yoshiyuki, Kong-Bing Tan, Vincent T. K. Chow, Prashant Rai, Bevin P. Engelward, Lu Yin

المساهمون: Massachusetts Institute of Technology. Department of Biological Engineering, Parrish, Marcus Curtis, Engelward, Bevin P., Abolhassani, Nona

المصدر: Springer Basel

مصطلحات موضوعية: DNA Repair, DNA damage, DNA repair, Inflammation, Lung injury, Biology, medicine.disease_cause, Article, Cell Line, Madin Darby Canine Kidney Cells, Cellular and Molecular Neuroscience, Dogs, Influenza A Virus, H1N1 Subtype, Orthomyxoviridae Infections, In vivo, medicine, Animals, Regeneration, Lung, Molecular Biology, Pharmacology, Ku70, Pneumonia, Cell Biology, Molecular biology, Comet assay, Oxidative Stress, Molecular Medicine, medicine.symptom, Oxidative stress, DNA Damage

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f337348d0518be202e09d3ca7a02415f
https://doi.org/10.1007/s00018-015-1879-1

المؤلفون: Paul S. Foster, Hong Yong Peh, W.S. Daniel Tan, Chen Wei Pow, W.S. Fred Wong, Tze Khee Chan

المصدر: Free radical biologymedicine. 110

مصطلحات موضوعية: 0301 basic medicine, Neutrophils, medicine.medical_treatment, Anti-Inflammatory Agents, medicine.disease_cause, Biochemistry, chemistry.chemical_compound, Mice, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Cell Movement, Smoke, COPD, Mice, Inbred BALB C, medicine.diagnostic_test, Tocotrienols, NF-kappa B, respiratory system, medicine.anatomical_structure, Pulmonary Emphysema, Prednisolone, Female, Tocotrienol, medicine.symptom, Bronchoalveolar Lavage Fluid, medicine.drug, Signal Transduction, STAT3 Transcription Factor, NF-E2-Related Factor 2, Inflammation, 03 medical and health sciences, Physiology (medical), Tobacco, medicine, Animals, Humans, Lung, business.industry, Vitamin E, medicine.disease, respiratory tract diseases, Disease Models, Animal, 030104 developmental biology, Bronchoalveolar lavage, 030228 respiratory system, chemistry, Gene Expression Regulation, Immunology, business, Reactive Oxygen Species, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecb3b01831fb3a8300a532994420956
https://pubmed.ncbi.nlm.nih.gov/28684161

المؤلفون: Tze Khee Chan, W.S. Fred Wong, W.S. Daniel Tan, Xin Yi Loh, David S.W. Ng, Wupeng Liao

المصدر: Phytomedicine. 21:1638-1644

مصطلحات موضوعية: Acute Lung Injury, Anti-Inflammatory Agents, Artesunate, Pharmaceutical Science, Lung injury, Protective Agents, medicine.disease_cause, Antioxidants, Cell Line, Pulmonary Disease, Chronic Obstructive, chemistry.chemical_compound, Tobacco, Drug Discovery, medicine, Animals, Humans, Lung, Protein kinase B, Pharmacology, Mice, Inbred BALB C, COPD, Membrane Glycoproteins, NADPH oxidase, medicine.diagnostic_test, biology, business.industry, Smoking, NADPH Oxidases, Catalase, medicine.disease, Artemisinins, Oxidative Stress, Bronchoalveolar lavage, Complementary and alternative medicine, chemistry, NADPH Oxidase 2, Immunology, biology.protein, Cytokines, Molecular Medicine, Female, business, Bronchoalveolar Lavage Fluid, Oxidative stress, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc35dfc94897edcc9613416d6c181bf2
https://doi.org/10.1016/j.phymed.2014.07.018

المؤلفون: Tze Khee Chan, Hong Yong Peh, W.S. Fred Wong, Wanxing Eugene Ho

المصدر: Pharmacology & Therapeutics. 142:126-139

مصطلحات موضوعية: Artemisinins, Antifungal Agents, medicine.medical_treatment, Anti-Inflammatory Agents, Syk, Dihydroartemisinin, Antineoplastic Agents, Biology, Pharmacology, Antiviral Agents, Antimalarials, chemistry.chemical_compound, parasitic diseases, medicine, Animals, Humans, Pharmacology (medical), Artemisinin, PI3K/AKT/mTOR pathway, Antiparasitic Agents, medicine.disease, chemistry, Drug development, Artesunate, Immunology, Malaria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc1f5368bd18f8585b1560f0a302022
https://doi.org/10.1016/j.pharmthera.2013.12.001

المؤلفون: Andrew Aswani, Joanna Manson, Kiyoshi Itagaki, Fausto Chiazza, Massimo Collino, Winston Liao Wupeng, Tze Khee Chan, W. S. Fred Wong, Carl J. Hauser, Chris Thiemermann, Karim Brohi

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, trauma, mitochondrial DNA, damage-associated molecular patterns, nucleic acid scavenger, multiple organ dysfunction syndrome, trauma hemorrhage, Toll-like receptor-9, sterile inflammation

Relation: https://figshare.com/articles/figure/Image_2_Scavenging_Circulating_Mitochondrial_DNA_as_a_Potential_Therapeutic_Option_for_Multiple_Organ_Dysfunction_in_Trauma_Hemorrhage_jpg/6229613

الاتاحة: https://doi.org/10.3389/fimmu.2018.00891.s002
https://figshare.com/articles/figure/Image_2_Scavenging_Circulating_Mitochondrial_DNA_as_a_Potential_Therapeutic_Option_for_Multiple_Organ_Dysfunction_in_Trauma_Hemorrhage_jpg/6229613

المؤلفون: Andrew Aswani, Joanna Manson, Kiyoshi Itagaki, Fausto Chiazza, Massimo Collino, Winston Liao Wupeng, Tze Khee Chan, W. S. Fred Wong, Carl J. Hauser, Chris Thiemermann, Karim Brohi

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, trauma, mitochondrial DNA, damage-associated molecular patterns, nucleic acid scavenger, multiple organ dysfunction syndrome, trauma hemorrhage, Toll-like receptor-9, sterile inflammation

Relation: https://figshare.com/articles/dataset/Table_2_Scavenging_Circulating_Mitochondrial_DNA_as_a_Potential_Therapeutic_Option_for_Multiple_Organ_Dysfunction_in_Trauma_Hemorrhage_docx/6229622

الاتاحة: https://doi.org/10.3389/fimmu.2018.00891.s005
https://figshare.com/articles/dataset/Table_2_Scavenging_Circulating_Mitochondrial_DNA_as_a_Potential_Therapeutic_Option_for_Multiple_Organ_Dysfunction_in_Trauma_Hemorrhage_docx/6229622

المؤلفون: Hock Meng Koh, David S.W. Ng, Tze Khee Chan, Chang Cheng, Shou Ping Guan, W.S. Fred Wong

المصدر: Phytomedicine. 20:853-860

مصطلحات موضوعية: Allergy, Guinea Pigs, Pharmaceutical Science, Pharmacology, Immunoglobulin E, Cell Degranulation, Mice, chemistry.chemical_compound, Immune system, Mallotus Plant, Cell Line, Tumor, Anti-Allergic Agents, Drug Discovery, medicine, Animals, Benzopyrans, Mast Cells, Anaphylaxis, Mice, Inbred BALB C, biology, Plant Extracts, Passive Cutaneous Anaphylaxis, Degranulation, Acetophenones, Smooth muscle contraction, Mast cell, medicine.disease, Rats, medicine.anatomical_structure, Complementary and alternative medicine, chemistry, Immunology, biology.protein, Molecular Medicine, Female, Rottlerin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f242a1802b276577435b39e5c96f791a
https://doi.org/10.1016/j.phymed.2013.03.012

المؤلفون: Judith C.W. Mak, Wing Sze Wong, Shou Ping Guan, D. S. W. Ng, Tze Khee Chan, W Tee, Hong Yong Peh, W. Ho, Chuan Cheng

المصدر: British Journal of Pharmacology. 168:1707-1718

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, biology, GCLM, Andrographolide, Glutathione peroxidase, Glutathione reductase, Glutathione, Lung injury, biology.organism_classification, chemistry.chemical_compound, GCLC, chemistry, Immunology, Andrographis paniculata

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c57c7a42fd54ac922a81961d24c0b1cc
https://doi.org/10.1111/bph.12054

المؤلفون: Tze Khee Chan, Wupeng Liao, W.S. Fred Wong, W.S. Daniel Tan, Li Li, Hong Yong Peh, Jinrui Dong

المصدر: 5.3 Allergy and Immunology.

مصطلحات موضوعية: Ribosomal Proteins, 0301 basic medicine, Small interfering RNA, Immunoglobulin E, Mice, 03 medical and health sciences, Gene expression, medicine, Animals, Gene silencing, Eukaryotic Small Ribosomal Subunit, Gene Silencing, Mice, Inbred BALB C, Reporter gene, Gene knockdown, biology, Genetic Therapy, Eosinophil, Research Papers, Asthma, RAW 264.7 Cells, 030104 developmental biology, medicine.anatomical_structure, Immunology, NIH 3T3 Cells, biology.protein, Cancer research, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c72f536eb65ff723b4dde5e5c843ad6
https://doi.org/10.1183/13993003.congress-2016.pa562

المؤلفون: Hong Yong Peh, Chu Hui Pang, Wupeng Liao, Wan Shun Daniel Tan, Suk Hiang Lau, W.S. Fred Wong, Tze Khee Chan, Vincent T. K. Chow

المصدر: 5.1 Airway Pharmacology and Treatment.

مصطلحات موضوعية: COPD, Lung, biology, business.industry, GCLM, Andrographolide, Inflammation, Lung injury, biology.organism_classification, medicine.disease, CXCL1, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Immunology, medicine, medicine.symptom, business, Andrographis paniculata

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d22343a3e5943f3a9df115fb12584849
https://doi.org/10.1183/13993003.congress-2016.pa4094

المؤلفون: Choon Nam Ong, Jianzhu Chen, Yie Hou Lee, Steven R. Tannenbaum, Wanxing Eugene Ho, Tze Khee Chan, Dahai Zheng, Yadunanda Kumar, Liang Cui

المساهمون: Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Chemistry, Koch Institute for Integrative Cancer Research at MIT, Chen, Jianzhu, Tannenbaum, Steven R

المصدر: Scientific Reports

مصطلحات موضوعية: Serum, 0301 basic medicine, Time Factors, Metabolite, Acute Lung Injury, Pneumonia, Viral, Lung injury, Biology, medicine.disease_cause, Mass Spectrometry, Article, Virus, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Orthomyxoviridae Infections, medicine, Influenza A virus, Animals, Metabolomics, Lung, Multidisciplinary, medicine.diagnostic_test, respiratory system, medicine.disease, Sphingolipid, respiratory tract diseases, Disease Models, Animal, 030104 developmental biology, Bronchoalveolar lavage, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, Viral pneumonia, Immunology, Metabolome, Bronchoalveolar Lavage Fluid

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa15ee4d87893e80d252306e7848cb2
https://doi.org/10.1038/srep26076

المؤلفون: D. S. W. Ng, H. Y. A. Lau, Wing Sze Wong, Shou Ping Guan, Wanxing Eugene Ho, J. S. Bian, Chang Cheng, A. H. M. Koh, Tze Khee Chan

المصدر: Allergy. 68:195-203

مصطلحات موضوعية: Allergy, Guinea Pigs, Immunoblotting, Immunology, Artesunate, In Vitro Techniques, Pharmacology, Immunoglobulin E, Cell Degranulation, Antimalarials, Mice, Random Allocation, chemistry.chemical_compound, Immune system, Anti-Allergic Agents, medicine, Animals, Humans, Immunology and Allergy, Mast Cells, Anaphylaxis, Immunity, Cellular, Dose-Response Relationship, Drug, biology, business.industry, Degranulation, Smooth muscle contraction, Mast cell, medicine.disease, Artemisinins, Asthma, Disease Models, Animal, medicine.anatomical_structure, chemistry, biology.protein, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f302b62a4a0fc3fdbacb3c9b88dd2a8
https://doi.org/10.1111/all.12077

المؤلفون: Tze Khee Chan, Chen Wei Pow, Choon Nam Ong, W.S. Daniel Tan, Jordan Petkov, Hong Yong Peh, W.S. Fred Wong

المصدر: Free Radical Biology and Medicine. 87:S139-S140

مصطلحات موضوعية: Gene isoform, business.industry, Vitamin E, medicine.medical_treatment, Pulmonary disease, Pharmacology, Biochemistry, chemistry.chemical_compound, chemistry, Physiology (medical), Immunology, Medicine, Cigarette smoke, Tocotrienol, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bac3135b4685b70a70880072631cb8d4
https://doi.org/10.1016/j.freeradbiomed.2015.10.361