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1Academic Journal
المؤلفون: Fuqua, Brie K, Lu, Yan, Frazer, David M, Darshan, Deepak, Wilkins, Sarah J, Dunn, Linda, Loguinov, Alex V, Kogan, Scott C, Matak, Pavle, Chen, Huijun, Dunaief, Joshua L, Vulpe, Chris D, Anderson, Gregory J
المصدر: Cellular and molecular gastroenterology and hepatology. 6(4)
مصطلحات موضوعية: Enterocytes, Duodenum, Animals, Mice, Inbred C57BL, Animals, Suckling, Mice, Knockout, Anemia, Disease Models, Animal, Body Weight, Iron, Ceruloplasmin, Cation Transport Proteins, Membrane Proteins, Body Size, Ligation, Organ Specificity, Phenotype, Female, Male, Absorption, Physiological, CP, ceruloplasmin, Cp-/-, mice lacking CP in the whole body, DAB, 3, 3′-diaminobenzidine, FDR, false discovery rate, FPN1, ferroportin 1, GI, gastrointestinal, HCI, hydrochloric acid, HEPH, hephaestin, Heph-/-, mice lacking HEPH in the whole body, Heph-/-Cp-/- or DKO, double-knockout mice lacking both HEPH and CP, Hephfl/fl, mice with floxed Heph alleles, Hephfl/flCp-/-, mice with floxed Heph alleles and lacking CP in the whole body, Hephint/int, mice lacking HEPH in the intestine alone, Hephint/intCp-/-, mice lacking HEPH in the intestine alone and lacking CP in the whole body, Hephsla/slaCp-/-, mice lacking CP in the whole body and expressing only the sla mutant form of HEPH, Intestinal Iron Absorption, Iron Deficiency Anemia, Iron Overload, MCF, multicopper ferroxidase, NTBI, non-transferrin bound iron, Non-Transferrin Bound Iron, PBS, phosphate-buffered saline, PCR, polymerase chain reaction, SD, standard deviation, TBST, Tris-buffered saline with 0.1% Tween-20, TF, transferrin, TIBC, total iron binding capacity, WT, wild-type, sla, sex-linked anemia, Mice, Inbred C57BL, Suckling, Knockout, Disease Models, Animal, Absorption, Physiological, CP, ceruloplasmin, Cp-/-, mice lacking CP in the whole body, DAB, 3, 3′-diaminobenzidine, FDR, false discovery rate, FPN1, ferroportin 1, GI, gastrointestinal, HCI, hydrochloric acid, HEPH, hephaestin, Heph-/-, mice lacking HEPH in the whole body, Heph-/-Cp-/- or DKO, double-knockout mice lacking both HEPH and CP, Hephfl/fl, mice with floxed Heph alleles, Hephfl/flCp-/-, mice with floxed Heph alleles and lacking CP in the whole body, Hephint/int, mice lacking HEPH in the intestine alone, Hephint/intCp-/-, mice lacking HEPH in the intestine alone and lacking CP in the whole body, Hephsla/slaCp-/-, mice lacking CP in the whole body and expressing only the sla mutant form of HEPH, MCF, multicopper ferroxidase, NTBI, non-transferrin bound iron, PBS, phosphate-buffered saline, PCR, polymerase chain reaction, SD, standard deviation, TBST, Tris-buffered saline with 0.1% Tween-20, TF, transferrin, TIBC, total iron binding capacity, WT, wild-type, sla, sex-linked anemia
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/22x9c1wp
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2Academic Journal
المؤلفون: Payen, Valéry L, Lavergne, Arnaud, Alevra Sarika, Niki, Colonval, Megan, Karim, Latifa, Deckers, Manon, Najimi, Mustapha, Coppieters, Wouter, CHARLOTEAUX, Benoit, Sokal, Etienne M, El Taghdouini, Adil
المصدر: JHEP Reports: Innovation in Hepatology, 3 (3), 100278 (2021-03-21)
مصطلحات موضوعية: BSA, bovine serum albumin, CC, cholangiocyte, CV, central vein, DEG, differentially expressed gene, EC, endothelial cell, ECM, extracellular matrix, Extracellular matrix, FFPE, formaldehyde-fixed paraffin embedded, GAG, glycosaminoglycan, GEO, Gene Expression Omnibus, GO, gene ontology, HEP, hepatocyte, HLA, human leukocyte antigen, HRP, horseradish peroxidase, HSC, hepatic stellate cell, Hepatocyte, ISH, in situ hybridisation, KLR, killer lectin-like receptor, LP, lymphoid cell, Liver cell atlas, MP, macrophage, MZ, midzonal, PC, pericentral, PP, periportal, PV, portal vein, TBS, Tris buffered saline, TSA, tyramide signal amplification, UMAP, uniform manifold approximation and projection, UMI, unique molecular identifier, VIM, vimentin, Zonation, scRNA-seq, single-cell RNA-sequencing, Immunology and Allergy, Internal Medicine, Hepatology, Gastroenterology, Human health sciences, Gastroenterology & hepatology, Sciences de la santé humaine, Gastroentérologie & hépatologie
Relation: https://api.elsevier.com/content/article/PII:S2589555921000549?httpAccept=text/xml; urn:issn:2589-5559; urn:issn:2589-5559
URL الوصول: https://orbi.uliege.be/handle/2268/288808
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3
المؤلفون: Koji Tanimoto, Taro Matsumoto, Yuki Nagaoka, Tomohiko Kazama, Chii Yamamoto, Koichiro Kano, Masahiro Nagaoka, Shu Saito, Yasuaki Tokuhashi, Kazuyoshi Nakanishi
المصدر: Regenerative Therapy, Vol 19, Iss, Pp 35-46 (2022)
Regenerative Therapyمصطلحات موضوعية: Adipose-derived stem cells, Medicine (General), MSCs, mesenchymal stem cells, RT-PCR, reverse transcription-polymerase chain reaction, DEGs, differentially expressed genes, PBS, phosphate-buffered saline, Biomedical Engineering, Dedifferentiated fat cells, Biomaterials, R5-920, FBS, fetal bovine serum, IFP, infrapatellar fat pad, FACS, fluorescence-activated cell sorting, Adipocytes, PCA, principal component analysis, QH573-671, HLA, human leukocyte antigen, WST-1, water soluble tetrazolium-1, SC, subcutaneous adipose tissue, TBS, Tris-buffered saline, DFATs, dedifferentiated fat cells, DFs, dermal fibroblasts, OA, osteoarthritis, Infrapatellar fat pad, Original Article, BSA, bovine serum albumin, Cytology, ASCs, adipose tissue-derived stem cells, Developmental Biology
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4Academic Journal
المؤلفون: Thana Lakshmi, K.
المصدر: International Journal of Zoology and Applied Biosciences, 4(4), 146-154,, (2019-07-31)
مصطلحات موضوعية: Hepatopancreas exctract, Haemagglutination, Tris-buffered saline, Calcium ions
Relation: https://doi.org/10.5281/zenodo.3356794; https://doi.org/10.5281/zenodo.3356795; oai:zenodo.org:3356795
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5
المؤلفون: Melinda A. Engevik, Robert Fultz, Susan Venable, Wenly Ruan, Yuko Mori-Akiyama, Yanling Zhao, James Versalovic, Zhongcheng Shi, Wa Du
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 717-737 (2022)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: Carcinogenesis, Neutrophils, RC799-869, HDN, high-density neutrophil, chemistry.chemical_compound, Histamine receptor, Mice, Neutrophil differentiation, HDGF, hepatoma-derived growth factor, Homeostasis, TBS-T, Tris Buffered Saline with Tween 20, Intestinal Mucosa, Original Research, TNF, tumor necrosis factor, Gastroenterology, ERK, extracellular signal-regulated kinase, Diseases of the digestive system. Gastroenterology, LDN, low-density neutrophil, Cell biology, H2R KO, histamine type 2 receptor deficient, CXCR, C-X-C Motif Chemokine Receptor, CRC, colorectal cancer, LPS, lipopolysaccharide, Signal transduction, medicine.symptom, Cimetidine, Histamine, TLR, Toll-like receptor, PCNA, proliferating cell nuclear antigen, PBS, phosphate-buffered saline, Inflammation, Proinflammatory cytokine, ROS, reactive oxygen species, HSC, hematopoietic stem cell, MDSC, myeloid-derived suppressor cell, DSS, dextran sulfate sodium, medicine, Animals, Neutrophil homeostasis, Colorectal Cancer, Innate immune system, Hepatology, HR, histamine receptor, WT, wild-type, qRT-PCR, quantitative reverse-transcription polymerase chain reaction, IL, interleukin, PD-L1, programmed death-ligand 1, UC, ulcerative colitis, chemistry, SM, squamous metaplasia, MAPK, mitogen-activated protein kinase, fMLP, N-formylmethionyl-leucyl-phenylalanine
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6
المؤلفون: Kim, So Young, Johns, Scott C., Gupta, Purva, Varki, Nissi, Fuster, Mark M
المصدر: Neoplasia (New York, N.Y.)
مصطلحات موضوعية: Adenoma, tumor, IHC, Immunohistochemistry, Doxy, doxycycline, Lung Neoplasms, Macrophage, Short Communication, Heparan sulfate, Mice, Transgenic, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory, Proto-Oncogene Proteins p21(ras), TAM, Tumor associated macrophage, Mice, Lymphocytes, Tumor-Infiltrating, HS, Heparan sulfate, Polysaccharides, CD11c, CD11c locus, Animals, Humans, HSPG, Heparan sulfate proteoglycan, Myeloid Cells, ICI, Immune checkpoint inhibition, Cancer, MHC, Major histocompatibility complex, Sulfates, T cell, Treg, Regulatory T cell, DC, Dendritic cell, CD11c Antigen, Mice, Inbred C57BL, APCs, Antigen presenting cells, Ndst, N-deacetylase/N-sulfotransferase, Mutation, Kras, LLC, Lewis lung carcinoma, BSA, Bovine Serum Albumin, Heparitin Sulfate, Sulfotransferases, TTBS, Tween tris buffered saline
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7
المؤلفون: Hygor N. Araujo, Ariclécio Cunha de Oliveira, Regina de Jesus das Neves, Tanes I. Lima, Renata Prado Vasconcelos, Paula Alexandre de Freitas, Keciany Alves de Oliveira, Marina Gabrielle Guimarães de Almeida, André Gustavo de Oliveira, Márcio V. Ramos, Leonardo R. Silveira, Bianca Cristine Favero-Santos, Dimitrius Santiago P.S.F. Guimarães
المصدر: Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 9, Pp 1061-1069 (2021)مصطلحات موضوعية: Proteases, Latex, HGP, Hepatic glucose production, Pharmaceutical Science, RM1-950, Pharmacology, PPAR, Peroxisome proliferator-activated receptor, UCP2, Mitochondrial uncoupling protein 2, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, FCCP, Oligomycin carbonyl cyanide 4 (trifluoromethoxy) phenylhydrazine, Calotropis procera, Bioactive proteins, Gene expression, Viability assay, PPRE, PPAR response element, Protein kinase A, Glycemic, chemistry.chemical_classification, Reactive oxygen species, CpPII, Major peptidase fraction treated with iodoacetamide, biology, Chemistry, AMPK, AMP-activated kinase protein, AMPK, DMEM, Dulbecco’s minimal essential medium, DMSO, Dimethyl sulfoxide, DHE, Dihydroethidium, OXPHOS, Oxidative phosphorylation, TBS-T, Tris buffered saline solution containing 0.1% Tween 20, biology.organism_classification, AUC, Area under the curve, Folk medicine, OCR, Oxygen consumption rate, CTL, Control, Original Article, Therapeutics. Pharmacology, Glycemia, LP, Soluble latex proteins from Calotropis procera, ROS, Reactive oxygen species
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8
المؤلفون: Jiansong Luo, Francesco De Pascali, G. Wendell Richmond, Amer M. Khojah, Jeffrey L. Benovic
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: WT, wild type, G-CSF, granulocyte colony stimulating factor, Receptors, CXCR4, pepducin, Primary Immunodeficiency Diseases, PBS, phosphate-buffered saline, Ser, serine, fs, frame shift, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, HBSS, Hank’s buffered saline solution, ERK, extracellular signal-regulated kinase, FBS, fetal bovine serum, PKC, protein kinase C, cell signaling, endocytosis, Humans, pS, phosphoserine, BRET, bioluminescence resonance energy transfer, Molecular Biology, beta-Arrestins, GPCR, G-protein-coupled receptor, extracellular-signal-regulated kinase (ERK), chemokine, chemokine receptor, Cell Biology, ELISA, enzyme-linked immunosorbent assay, Bis I, bisindolylmaleimide I, G-protein-coupled receptor (GPCR), Chemokine CXCL12, protein phosphorylation, TBS, Tris-buffered saline, beta-Arrestin 1, protein degradation, TBST, Tris-buffered saline with Tween, AIP4, atrophin-1-interacting protein 4, Warts, GRK, G-protein-coupled receptor kinase, Research Article, WBC, white blood cell
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9
المؤلفون: Christopher Carlsten, Maria J. Aristizabal, Rachel L. Clifford, Hang Li, Christopher F. Rider, Wayne Tse, Weiping Wen, Min Hyung Ryu
المصدر: Journal of Allergy and Clinical Immunology. 147:1671-1682
مصطلحات موضوعية: Male, 0301 basic medicine, Chemokine, Methyltransferase, Tris-buffered saline, medicine.disease_cause, Mixed Function Oxygenases, chemistry.chemical_compound, 0302 clinical medicine, Allergen, Immunology and Allergy, DNA Modification Methylases, Lung, Vehicle Emissions, Inhalation Exposure, Cross-Over Studies, biology, Middle Aged, respiratory system, 3. Good health, 030220 oncology & carcinogenesis, Cytokines, Female, Bronchoalveolar Lavage Fluid, Adult, Immunology, Bronchi, Respiratory Mucosa, DNA methyltransferase, Cell Line, Young Adult, 03 medical and health sciences, Double-Blind Method, Air Pollution, Proto-Oncogene Proteins, Respiratory Hypersensitivity, medicine, Humans, Asthma, 5-Hydroxymethylcytosine, business.industry, dNaM, Allergens, medicine.disease, respiratory tract diseases, 030104 developmental biology, chemistry, 13. Climate action, biology.protein, business
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10
المؤلفون: Narihito Nagoshi, Taro Matsumoto, Rina Fujii-Tezuka, Ichiro Morioka, Hideyuki Okano, Shori Takahashi, Hideo Mugishima, Mika Ishige-Wada
المصدر: Regenerative Therapy
Regenerative Therapy, Vol 16, Iss, Pp 1-11 (2021)مصطلحات موضوعية: 0301 basic medicine, Medicine (General), DMEM, Dulbecco's modified Eagle medium, MSCs, mesenchymal stem cells, WJ, Wharton's jelly, FGF-2, fibroblast growth factor-2, ASMA, α-smooth muscle actin, vWF, von Willebrand factor, PDGF, platelet-derived growth factor, 0302 clinical medicine, Immunophenotyping, βME, β-mercaptoethanol, DAPI, 4′,6-diamino-2-phenylindole, p75 neurotrophin receptor, UA, umbilical artery, CFU-F, colony-forming unit fibroblast, FSK, forskolin, EdU, 5-ethynyl-2′-deoxyuridine, UC, umbilical cord, Neural crest, EGFP, enhanced green fluorescent protein, Cell biology, medicine.anatomical_structure, NCSCs, neural crest-derived stem cells, CD146, Original Article, Pericyte, Neural crest stem cells, Stem cell, α-MEM, alpha-modified minimum essential medium, BDNF, bone-derived neurotrophic factor, PBS, phosphate-buffered saline, Biomedical Engineering, Neurosphere, Biology, p75NTR, p75 neurotrophin receptor, Biomaterials, MAP2, microtubule-associated protein 2, 03 medical and health sciences, R5-920, FBS, fetal bovine serum, medicine, CD90, NG2, neuron-glial antigen 2, Umbilical cord, EGF, epidermal growth factor, QH573-671, Mesenchymal stem cell, GFAP, glial fibrillary acidic protein, NF200, neurofilament 200, TBS, Tris-buffered saline, 030104 developmental biology, UV, umbilical vein, Mesenchymal stem cells, sense organs, Cytology, RA, all-trans-retinoic acid, 030217 neurology & neurosurgery, Developmental Biology
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المؤلفون: Kim E. Barrett, Mamata Sivagnanam, Jocelyn Young, Barun Das, Kevin Okamoto, John Rabalais
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1353-1371 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: Malabsorption, Cellular differentiation, Mutant, Enteroendocrine cell, RC799-869, IEC, intestinal epithelial cell, Pathogenesis, Mice, chemistry.chemical_compound, UPR, unfolded protein response, Intestinal Mucosa, Original Research, EDM, enteroid-derived monolayer, MVID, microvillous inclusion disease, Gastroenterology, qRT-PCR, quantitative real-time polymerase chain reaction, Cell Differentiation, Epithelial cell adhesion molecule, ELISA, enzyme-linked immunosorbent assay, Congenital Diarrhea, Diseases of the digestive system. Gastroenterology, Epithelial Cell Adhesion Molecule, mRNA, messenger RNA, Cell biology, EpCAM, epithelial cell adhesion molecule, ISC, intestinal stem cell, Defective Enterocyte, Disease Susceptibility, IHC, immunohistochemistry, Signal Transduction, Enteroendocrine Cells, CTE, congenital tufting enteropathy, PBS, phosphate-buffered saline, Notch signaling pathway, CHGA, chromogranin A, Biology, Permeability, Intestinal Failure, Malabsorption Syndromes, medicine, Animals, Humans, Intestinal epithelial cell differentiation, Genetic Predisposition to Disease, NICD, Notch intracellular domain, Hepatology, Congenital Tufting Enteropathy, medicine.disease, Congenital tufting enteropathy, TBS, Tris-buffered saline, Disease Models, Animal, PAS, periodic acid-Schiff, Glucose, Gene Expression Regulation, chemistry, EpCAM, Diarrhea, Infantile, Mutation, Intestinal Cell Differentiation, Cancer research, H&E, hematoxylin and eosin, Biomarkers, Immunostaining
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12
المؤلفون: Rui Wang, Dandan Zhong, Yiqing Qiu, Jingni Wu, Yongliang Zhu, Zhenya Song, Jingwen Liu, Hongping Wang
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1433-1455 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: Models, Molecular, ANKRD22, ankyrin repeat domain-containing protein 22, RC799-869, BrdU+, bromodeoxyuridine-incorporating, Receptors, G-Protein-Coupled, Mice, FACS, fluorescence-activated cell sorting, Macrophage, IFN-γ, interferon-γ, Receptor, Wnt Signaling Pathway, TNF-α, tumor necrosis factor α, Original Research, Mice, Knockout, medicine.diagnostic_test, Chemistry, Wnt, Wingless/Int1, Gastroenterology, LGR5, ELISA, enzyme-linked immunosorbent assay, Diseases of the digestive system. Gastroenterology, FCM, flow cytometry, Immunohistochemistry, mRNA, messenger RNA, Ssea, stage-specific embryonic antigen, Mitochondria, Sox, SRY-box transcription factor, NFAT, nuclear factor of activated T cells, Rhod-2, Dihydrorhod-2, c-Myc, Myc proto-oncogene protein, AXIN2, axis inhibition protein 2, LPS, lipopolysaccharide, Tumor necrosis factor alpha, FITC, fluorescein isothiocyanate, RIPA, radioimmunoprecipitation assay, medicine.symptom, IL1α, interleukin-1α, IHC, immunohistochemistry, Targeted Gene Repair, Gastric Mucosal Injury, PBS, phosphate-buffered saline, Stomach Diseases, Inhibitory Compound, Inflammation, THP-1, Human myeloid leukemia mononuclear cell, Immunophenotyping, Flow cytometry, Structure-Activity Relationship, FBS, fetal bovine serum, Drug Development, In vivo, Cell Line, Tumor, medicine, Animals, Progenitor cell, Cell Proliferation, Cd, cluster of differentiation, Hepatology, Macrophages, Lgr5+, leucine-rich repeat-containing G-protein–coupled receptor 5–positive, Membrane Proteins, PE, Phycoerythrin, Macrophage Activation, WT, wild-type, qRT-PCR, quantitative reverse-transcription polymerase chain reaction, ANKRD22, TBS, Tris-buffered saline, Disease Models, Animal, Gene Expression Regulation, Mist, Muscle, intestine and stomach expression, Gastric Mucosa, CaMKII, calmodulin-dependent protein kinase II, Cancer research, EPC, epithelial progenitor cell, DMEM, Dulbecco’s modified Eagle medium, Epithelial Progenitor Cells, Biomarkers
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المؤلفون: Ping Zhang, Dingyuan Ma, Li-Ying Peng, Ning-Yuan Sun, Jun Chen, Xiao-Wei Zhang, Weiwei Tang, Lin An
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1397-1413 (2020)مصطلحات موضوعية: LDH, lactic dehydrogenase, MMP, mitochondrial membrane potential, Hepatocellular carcinoma, 7-AAD, 7-aminoactinomycin D, NS, no significance, TBST, Tris-buffered saline with Tween solution, DMSO, dimethyl sulfoxide, ECL, enhanced chemiluminescence, NC, negative control, 0302 clinical medicine, GSDME, gasdermin E, General Pharmacology, Toxicology and Pharmaceutics, N-GSDME, N-terminal GSDME, PARP, poly ADP-ribose polymerase, Caspase, ANOVA, analysis of variance, p-MEK, phosphorylated-MEK, DCFH-DA, dye 2,7-dichlorofluoresce diacetate, MEK, mitogen-activated and extracellular signal-regulated kinase, 0303 health sciences, DMEM, Dulbecco's modified Eagle's medium, biology, Kinase, Chemistry, Pyroptosis, HRP, horseradish peroxidase, PI3K, phosphatidylinositol 3-kinase, gRNA, guide RNA, i.p., intraperitoneal, VEGF, vascular endothelial growth factor, PBS, phosphate-based buffer, SDS-PAGE, sodium dodecyl sulphate-polyacrylamide gel electrophoresis, CRISPR, clustered regularly interspaced short palindromic repeats, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, 030220 oncology & carcinogenesis, Original Article, FITC, fluorescein isothiocyanate, RIPA, radioimmunoprecipitation assay, p-AKT, phosphorylated-AKT, IgG (H + L), immunoglobulin G (heavy chain + light chain), Intracellular, Cell death, Programmed cell death, HepG2, Miltirone, TCGA, the Cancer Genome Atlas, p-ERK1/2, phosphorylated-ERK1/2, Caspase 3, IC50, the half maximal inhibitory concentration, mTOR, mammalian target of rapamycin, MEM, minimum essential medium, PI, propidium iodide, 03 medical and health sciences, CCK-8, cell counting kit-8, ROS, reactive oxygen species, FBS, fetal bovine serum, i.v., intravenous, Viability assay, GSDMD, gasdermin D, AKT, AKT serine/threonine kinase, also known as protein kinase B, NMR, nuclear magnetic resonance, Cas9, caspase 9, 030304 developmental biology, Hepa1-6, KO, knockout, lcsh:RM1-950, lcsh:Therapeutics. Pharmacology, BAX, BCL2-associated X, Apoptosis, NAC, N-acetyl cysteine, ERK1/2, extracellular regulated protein kinases 1/2, Cancer research, biology.protein, H&E, hematoxylin and eosin, GSDME, HCC, hepatocellular carcinoma, SD, standard deviation, MS, mass spectrum
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المؤلفون: Jun Huang, Ke Liu, Guido Kroemer, Changfeng Li, Borong Zou, Daolin Tang, Rui Kang, Jiao Liu, Herbert J. Zeh
المساهمون: Soochow University, Southern Medical University [Guangzhou], Aalto University, University of Texas Southwestern Medical Center, Métabolisme, cancer et immunité = Metabolism, Cancer & Immunity [CRC] (Equipe labellisée Ligue contre le cancer), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Gestionnaire, HAL Sorbonne Université 5
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2022, 13 (2), pp.483-500. ⟨10.1016/j.jcmgh.2021.09.008⟩
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 483-500 (2022)مصطلحات موضوعية: Necrosis, MPO, myeloperoxidase, RC799-869, Acinar Cells, Pharmacology, SLC40A1, solute carrier family 40 member 1, GPX4, Lipid peroxidation, chemistry.chemical_compound, Mice, GSH, glutathione, Trypsin, Sensitization, Original Research, DPPH, 2,2-diphenyl-1-picrylhydrazyl, LDH, lactate dehydrogenase, Cell Death, Sterile Inflammation, Gastroenterology, PSMD4, proteasome 26S subunit, non–adenosine triphosphatase 4, Diseases of the digestive system. Gastroenterology, mRNA, messenger RNA, PTGS2, prostaglandin-endoperoxide synthase 2, medicine.anatomical_structure, GPX4, glutathione peroxidase 4, shRNA, short hairpin RNA, qPCR, quantitative polymerase chain reaction, medicine.symptom, IL1B, interleukin 1β, Ceruletide, medicine.drug, Programmed cell death, ARNTL, aryl hydrocarbon receptor nuclear translocator-like, cDNA, complementary DNA, p-MLKL, phosphorylated mixed-lineage kinase domain-like pseudokinase, medicine, Acinar cell, mPAC, mouse primary pancreatic acinar cell, Animals, Ferroptosis, STI, soybean trypsin inhibitor, ACSL4, acyl-CoA synthetase long chain family member 4, MDA, malondialdehyde, KO, knockout, Hepatology, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Digestive Enzyme, medicine.disease, WT, wild-type, CoQ10, coenzyme Q10, [SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, HMGB1, high mobility group box 1, IL, interleukin, Disease Models, Animal, TBST, Tris-buffered saline with 0.1% Tween 20 detergent, chemistry, Pancreatitis, Animal Model
وصف الملف: application/pdf
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15Academic Journal
المؤلفون: David Cadagan, Robert Barrington, Paul Murray, and Stephen Merry
مصطلحات موضوعية: Adipocyte, Type 2 Diabetes, Insulin, Leptin, Adipokines, Hormones, Steroidogenesis, Alkaline Phosphatise, Body Mass Index, Enzyme-Linked Immonosorbent Assay, Polyacrylamide Gel Electrophoresis, Phosphate Buffered Saline, Phosphatase and Tensin Homolog, Tris Buffered Saline
وصف الملف: application/pdf
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المؤلفون: Michael D. Onken, Sarah E. Noda, Kevin M. Kaltenbronn, Cheryl Frankfater, Carol M. Makepeace, Nikki Fettig, Kisha D. Piggott, Philip L. Custer, Joseph E. Ippolito, Kendall J. Blumer
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Uveal Neoplasms, RRID, Research Resource Identifier, 2-DG6P, 2-deoxy-d-glucose-6-phosphate, oncogenes, Carcinogenesis, MST, Mito Stress Test, ROI, region of interest, TCA, tricarboxylic acid, DMSO, dimethyl sulfoxide, MEK, mitogen-activated protein kinase/extracellular signal–regulated kinase kinase, Biochemistry, OxPhos, oxidative phosphorylation, NSG, NOD scid gamma, 2-DG, 2-deoxyglucose, Erk, extracellular signal–regulated protein kinase, Cell Line, Tumor, Gq/11, Humans, OCR, oxygen consumption rate, TBST, Tris-buffered saline with Tween-20, Molecular Biology, Melanoma, PDX, patient-derived xenograft, 18F-FDG, 18F-fluorodeoxyglucose, ECAR, extracellular acidification rate, ATCC, American Type Culture Collection, BAP1, BRCA1-associated protein 1, GST, Glycolytic Stress Test, Gq/11, Gq or G11, I.I., integrated fluorescence intensities, MEKi, MEK inhibitor, Cell Biology, PKCi, PKC inhibitor, MEF, mouse embryonic fibroblast, GTP-Binding Protein alpha Subunits, BRAF, B-Raf proto-oncogene serine/threonine-protein kinase, CT, computed tomography, AMPK, AMP-activated protein kinase, mTORC1, mechanistic target of rapamycin complex 1, FR, FR900359, GTP-Binding Protein alpha Subunits, Gq-G11, FCCP, carbonyl cyanide-p-trifluoromethoxyphenylhydrazone, uveal melanoma, signaling, metabolism, Research Article, UM, uveal melanoma
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المؤلفون: Hristina R. Zhekova, Mirna Damergi, Gülru Kayık, Ira Kurtz, Alexander Pushkin, Natalia Abuladze, Debra Kurtz, Rustam Azimov, Liyo Kao, Sergei Y. Noskov
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Kidney Disease, Protein Conformation, Biochemistry, SLC4 proteins, Medical and Health Sciences, SLC4, Solute Carrier Family 4, VMD, Visual Molecular Dynamics, POPC, 1-Palmitoyl-2-oleoylphosphatidylcholine, pRTA, Proximal Renal Tubilar Acidosis, CHARMM, Chemistry at Harvard Macromolecular Mechanics, cryo-EM, cryo-electron microscopy, ECL, Enhanced Chemiluminescent, TM, Transmembrane Segment, biology, Chemistry, SILCS, Site Identification by Ligand Competitive Saturation, HEK293, Human Embryonic Kidney Cell Line 293, Biological Sciences, Ligand (biochemistry), pHi, Internal pH, NPT, MD ensemble with constant number of particles (N), pressure (P), and temperature (T), Transmembrane domain, NVT, MD ensemble with constant number of particles (N), volume (V), and temperature (T), DIDS, 4,4′-diisothiocyanatostilbene-2, 2′-disulfonic acid, transporter, BCECF-AM, 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein tetrakis(acetoxymethyl) ester, hAE1, Human Anion Exchanger 1, Research Article, Protein Binding, Biochemistry & Molecular Biology, GCMC, Grand Canonical Monte Carlo, TBSTM, Tris buffered saline with polyethylene glycol sorbitan monolaurate, 1.1 Normal biological development and functioning, membrane transport, EIPA, 5-(N-ethyl-N-isopropyl)-amiloride, NBCe1, MD, Molecular Dynamics, Molecular Dynamics Simulation, 03 medical and health sciences, Ion binding, Underpinning research, OF, Outward-Facing, Humans, TBST, Tris buffered saline, Binding site, Anion binding, Molecular Biology, Band 3, computer modeling, SILCS, Solute Carrier Proteins, hNBCe1, Human Electrogenic Sodium Bicarbonate Cotransporter 1, Binding Sites, 030102 biochemistry & molecular biology, Biological Transport, Cell Biology, Membrane transport, electrophysiology, molecular dynamics, substrate binding sites, 030104 developmental biology, Ion homeostasis, NAMD, Nanoscale Molecular Dynamics, Chemical Sciences, biology.protein, Biophysics
وصف الملف: application/pdf
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المؤلفون: Cédric Laguri, Isabel Ayala, Karine Giandoreggio-Barranco, Jean-Pierre Simorre, Tiago Baeta, Paola Sperandeo, Elisabete C.C. M. Moura, Alessandra Polissi
المساهمون: Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)
المصدر: The Journal of Biological Chemistry
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, pp.101313. ⟨10.1016/j.jbc.2021.101313⟩
Journal of Biological Chemistry, 2021, pp.101313. ⟨10.1016/j.jbc.2021.101313⟩مصطلحات موضوعية: Lipopolysaccharides, Models, Molecular, Accelerated Communication, nuclear magnetic resonance (NMR), ATPase, STD, saturation transfer difference, Adenylate kinase, ATP-binding cassette transporter, Biochemistry, adenylate kinase, Lipopolysaccharide transport, 03 medical and health sciences, 0302 clinical medicine, Adenosine Triphosphate, Escherichia coli, Inner membrane, AK, adenylate kinase, Molecular Biology, OM, outer membrane, 030304 developmental biology, 0303 health sciences, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], biology, Chemistry, Escherichia coli Proteins, Membrane Proteins, Biological Transport, Cell Biology, Periplasmic space, LptAm, monomeric version of LptA, Transmembrane protein, NMR, Cell biology, IM, inner membrane, TBS, Tris-buffered saline, biology.protein, SMA, styrene-maleic acid, cell wall, LPS, lipopolysaccharide, ATP-Binding Cassette Transporters, ABC transporter, Bacterial outer membrane, Carrier Proteins, 030217 neurology & neurosurgery, lipopolysaccharide (LPS), Lpt, lipopolysaccharide transporter system, TM, transmembrane
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المؤلفون: Andrew Dickson, Benjamin R. Stromberg, Christine Insinna, Matthew K. Summers, Yosup Rhee, Adrian E. Torres, Debjani Pal, Christopher J. Westlake, Mayank Singh, Amy C. Burrows
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: SCFβTRCP, SKP1–CUL1–F-box in complex with the β-transducing repeat–containing protein, DNA damage response, Biochemistry, Deubiquitinating enzyme, S Phase, Histones, Enzyme Stability, HDAC6, histone deacetylase 6, checkpoint control, deubiquitination, Ub, ubiquitin, βTRCP, β-transducing repeat–containing protein, biology, Chemistry, Cell cycle, Cell biology, USP37, DUB, deubiquitinating enzyme, ATR, ataxia telangiectasia and Rad3-related, MCF-7 Cells, cell cycle, PBST, PBS with Tween-20, Research Article, DNA Replication, CHK1, CHK1, checkpoint kinase 1, ubiquitination, APH, aphidicolin, DDR, DNA damage response, Genomic Instability, CHX, cycloheximide, APC/CCDH1, cyclosome in complex with the activator CDH1, GST, glutathione-S-transferase, Endopeptidases, Humans, CHEK1, APC/C, anaphase-promoting complex/Cyclosome, TBST, Tris-buffered saline with Tween-20, Molecular Biology, Mitosis, Cell growth, DNA replication, Cell Biology, SCF, SKP1–CUL1–F-box, HDAC6, HCT116 Cells, Checkpoint Kinase 1, biology.protein, BSA, bovine serum albumin, Ataxia telangiectasia and Rad3 related, HU, hydroxyurea, DNA Damage, HeLa Cells
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المؤلفون: Elena V. Olshevskaya, Alexander M. Dizhoor, Igor V. Peshenko
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Retinal degeneration, genetic structures, CORD6, cone–rod dystrophy 6, ONL, outer nuclear layer, Biochemistry, chemistry.chemical_compound, Mice, GCAP, guanylyl cyclase–activating protein, RD3, retinal degeneration-3 protein, Mice, Knockout, medicine.diagnostic_test, OCT, optical coherence tomography, CNG, cyclic nucleotide–gated channel, Nuclear Proteins, Photoreceptor outer segment, eye, Cell biology, Isoenzymes, medicine.anatomical_structure, calcium-binding proteins, GUCY2D, TTBS, Tris-buffered saline containing 0.5% Tween-20, RD3, Retinitis Pigmentosa, Research Article, Photoreceptor Cells, Vertebrate, Receptors, Cell Surface, HEK293, human embryonic kidney cells 293, LCA12, Leber's congenital amaurosis type 12, cyclic GMP, RetGC, medicine, RetGC, the retinal membrane guanylyl cyclase, Animals, Humans, ROS, rod outer segment, guanylate cyclase (guanylyl cyclase), Outer nuclear layer, Molecular Biology, Retina, ERG, electroretinography, GCAP, Dystrophy, Retinal, Cell Biology, medicine.disease, photoreceptor, Guanylate Cyclase-Activating Proteins, HEK293 Cells, chemistry, Guanylate Cyclase, Mutation, retinal degeneration, sense organs, Electroretinography