يعرض 1 - 20 نتائج من 52 نتيجة بحث عن '"Transport machinery"', وقت الاستعلام: 0.51s تنقيح النتائج
  1. 1
    Conference

    المصدر: Human Factors and Systems Interaction

    Relation: info:eu-repo/grantAgreement/MESTD/inst-2020/200105/RS//; Support Systems for Smart, Ergonomic and Sustainable Mining Machinery Workplaces – SmartMiner, #GRANT No. 5151 supported by the Science Fund of the Republic of Serbia; https://machinery.mas.bg.ac.rs/handle/123456789/6916; http://machinery.mas.bg.ac.rs/bitstream/id/17406/978-1-958651-60-5_14.pdf

    الاتاحة: https://machinery.mas.bg.ac.rs/handle/123456789/6916
    https://doi.org/10.54941/ahfe1003598
    http://machinery.mas.bg.ac.rs/bitstream/id/17406/978-1-958651-60-5_14.pdf

  2. 2
    Academic Journal
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    Academic Journal
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    Academic Journal
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    Academic Journal
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    Academic Journal

    المصدر: Civil Engineering and Environmental Systems

    Relation: info:eu-repo/grantAgreement/ScienceFundRS/Zeleni/5151/RS//; info:eu-repo/grantAgreement/MESTD/inst-2020/200105/RS//; https://machinery.mas.bg.ac.rs/handle/123456789/7746

    الاتاحة: https://machinery.mas.bg.ac.rs/handle/123456789/7746
    https://doi.org/10.1080/10286608.2024.2313753

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    Academic Journal
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    Academic Journal

    المؤلفون: Wada, Jun, Kanwar, Yashpal S.

    المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1998 Jan 01. 95(1), 144-149.

  9. 9
    Conference

    وصف الملف: application/pdf

    Relation: Инновационное развитие техники и технологий наземного транспорта. — 2022. — Екатеринбург, 2023; Летнев К. Ю. К вопросу подготовки студентов в сфере техники и технологий наземного транспорта / К. Ю. Летнев, В. В. Давыдова. — Текст : электронный // Инновационное развитие техники и технологий наземного транспорта : IV Всероссийская научно-практическая конференция (Екатеринбург, 16 декабря 2022 г.). — Екатеринбург: Издательство Уральского университета, 2023. — С. 214-217.; http://elar.urfu.ru/handle/10995/122938

  10. 10
    Conference

    المؤلفون: Leva, A, Terraneo, F, Fornaciari, W

    المساهمون: Leva, A, Terraneo, F, Fornaciari, W

    وصف الملف: STAMPA

    Relation: info:eu-repo/semantics/altIdentifier/isbn/979-8-3503-1543-1; info:eu-repo/semantics/altIdentifier/wos/WOS:001042336800012; ispartofbook:Proceedings of 2023 31st Mediterranean Conference on Control and Automation (MED); https://ieeexplore.ieee.org/document/10185793; firstpage:67; lastpage:72; numberofpages:6; serie:MEDITERRANEAN CONFERENCE ON CONTROL & AUTOMATION; https://hdl.handle.net/11311/1256102; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85167837902

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  12. 12
    Dissertation/ Thesis

    المؤلفون: Tavares, Lucas Alves

    Thesis Advisors: Silva, Luis Lamberti Pinto da

    مصطلحات موضوعية: 2 depletion, acts in the CD4 down-regulation induced by Nef. These studies contribute to a better understanding on the molecular mechanisms involved in Nef activit, although not need charging ubiquitination, and it is estimated that there are currently at least 36.9 million people infected with the virus. During the replication cycle, and only the AP-1 variant comprising ?2, another subunit of AP-1, AP-1, AP-1 subunits. By pull-down technique, AP-2, AP-2 and AP-3 are potentially heterogeneous due to the existence of multiple subunits isoforms encoded by different genes. However, AP-3 complexes and Nef does not appear to interact with AP-4 and AP-5 subunits. However, being an important protein in the endo-lysosomal system. Furthermore, but also seem to compose AP-1 complex with distinct cell functions, but not ?1, but not ?1 depletion, but the molecular mechanisms are still incompletely understood. Nef forms a tripartite complex with the cytosolic tail of the CD4 and adapter protein, by flow cytometry assay, compromises the reduction of surface CD4 levels induced by Nef. Immunofluorescence microscopy analysis also revealed that ?2 depletion impairs the red, compromising the efficient CD4 degradation by Nef. Moreover, depends on the proteins from ESCRTs (Endosomal Sorting Complexes Required for Transport) machinery and the action of Alix, an accessory protein ESCRT, ESCRT, HIV promotes several changes in the physiology of the host cell to promote their survival and enhance replication. The fast progression of HIV-1 in hu, HIV-1, inducing CD4 internalization and lysosome degradation. Previous research has demonstrated that CD4 target to lysosomes by Nef involves targeting of th, internalized CD4 accumulates in enlarged HRS-GFP positive endosomes, is required in Nef-mediated targeting of CD4 to lysosomes and the ?2 participation in this process is conserved by Nef from different viral strains. F, MVB, Nef, not ?1-adaptin, one is the most important is the down-regulation of proteins from the immune response, our data from immunoblots indicated that ?2- adaptin, regulação negativa de CD4, resulted in decreased cellular levels of ?1 and ?2 and, resulting in CD4 accumulation in primary endosomes. Knockdown of ?1A, such as the CD4 receptor. It is known that this action causes CD4 degradation in lysosome, the results indicate that ?-adaptins isoforms not only have different functions, the results indicate that ?2-adaptin is a molecule that is essential for CD4 targeting by Nef to ESCRT/MVB pathway, The Human Immunodeficiency Virus (HIV) is the etiologic agent of Acquired Immunodeficiency Syndrome (AIDS). AIDS is a disease which has a global distr, the role of Nef interaction with AP-1 or AP-3 in CD4 down-regulation is poorly understood. Furthermore, there are few studies to demonstrate if the different combinations of APs isoforms are form and if they have distinct functional properties. This stud, this study aimed to characterize the involvement of AP-1 complex in the down-regulation of CD4 by Nef HIV-1 through the functional study of the two is, this work contributes with the understanding of primordial process regulation on intracellular trafficking of transmembrane proteins., upon artificially stabilizing ESCRT-I in early endosomes, via overexpression of HRS, we showed that Nef is able to interact with ?2. In addition, where co-localize with ?2. Together, which may also help to improve the understanding of the HIV pathogenesis and the related syndrome. In addition, y1-adaptina, y2-adaptina

    وصف الملف: application/pdf

  13. 13
    Academic Journal
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  16. 16

    وصف الملف: application/pdf

    Relation: Manzano-López, Javier; Rodríguez-Gallardo, Sofía; Sabido-Bozo, Susana; Cortés-Gómez, Alejandro; Pérez-Linero, Ana María; Lucena, Rafael; Cordones Romero, Antonio; López, Sergio; Aguilera-Romero, Auxiliadora; Muñíz, Manuel. Crosslinking assay to study a specific cargo-coat interaction through a transmembrane receptor in the secretory pathway. https://doi.org/10.1371/journal.pone.0263617 . http://hdl.handle.net/10261/305197; https://doi.org/10.1371/journal.pone.0263617.s002; Sí; Manzano-López, Javier; Rodríguez-Gallardo, Sofía; Sabido-Bozo, Susana; Cortés-Gómez, Alejandro; Pérez-Linero, Ana María; Lucena, Rafael; Cordones Romero, Antonio; López, Sergio; Aguilera-Romero, Auxiliadora; Muñíz, Manuel; 2022; S1 Protocols - Crosslinking assay to study a specific cargo-coat interaction through a transmembrane receptor in the secretory pathway [Dataset]; Figshare; https://doi.org/10.1371/journal.pone.0263617.s002; http://hdl.handle.net/10261/331785

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    وصف الملف: image/tiff

    Relation: Manzano-López, Javier; Rodríguez-Gallardo, Sofía; Sabido-Bozo, Susana; Cortés-Gómez, Alejandro; Pérez-Linero, Ana María; Lucena, Rafael; Cordones Romero, Antonio; López, Sergio; Aguilera-Romero, Auxiliadora; Muñíz, Manuel. Crosslinking assay to study a specific cargo-coat interaction through a transmembrane receptor in the secretory pathway. https://doi.org/10.1371/journal.pone.0263617 . http://hdl.handle.net/10261/305197; https://doi.org/10.1371/journal.pone.0263617.s001; Sí; Manzano-López, Javier; Rodríguez-Gallardo, Sofía; Sabido-Bozo, Susana; Cortés-Gómez, Alejandro; Pérez-Linero, Ana María; Lucena, Rafael; Cordones Romero, Antonio; López, Sergio; Aguilera-Romero, Auxiliadora; Muñíz, Manuel; 2022; S1 Fig - Crosslinking assay to study a specific cargo-coat interaction through a transmembrane receptor in the secretory pathway [Dataset]; Figshare; https://doi.org/10.1371/journal.pone.0263617.s001; http://hdl.handle.net/10261/331783

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    المؤلفون: Baeta, Tiago

    المساهمون: Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Université Grenoble Alpes [2020-....], Jean-Pierre Simorre, STAR, ABES

    المصدر: Biochemistry [q-bio.BM]. Université Grenoble Alpes [2020-..], 2020. English. ⟨NNT : 2020GRALV037⟩

    وصف الملف: application/pdf

  19. 19
    Dissertation/ Thesis

    المؤلفون: Baeta, Tiago

    المساهمون: Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Université Grenoble Alpes 2020-., Jean-Pierre Simorre

    المصدر: https://theses.hal.science/tel-03198787 ; Biochemistry [q-bio.BM]. Université Grenoble Alpes [2020-.], 2020. English. ⟨NNT : 2020GRALV037⟩.

    Relation: NNT: 2020GRALV037

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    Dissertation/ Thesis