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1
المؤلفون: Ellen G. J. Ripmeester, Tim J. M. Welting, Guus G. H. van den Akker, Don A. M. Surtel, Jessica S. J. Steijns, Andy Cremers, Lodewijk W. van Rhijn, Marjolein M. J. Caron
المساهمون: Orthopedie, RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation, MUMC+: MA Orthopedie (9), RS: CAPHRI School for Public Health and Primary Care, MUMC+: MA Orthopedie (3)
المصدر: PLOS ONE, 17(2):e0263430. Public Library of Science
PLoS ONE, Vol 17, Iss 2 (2022)مصطلحات موضوعية: Transcription, Genetic, Bone Morphogenetic Protein 7, Up-Regulation/drug effects, Core Binding Factor Alpha 1 Subunit, urologic and male genital diseases, Transcription, Genetic/drug effects, Cell Proliferation/drug effects, POLYMERASE-I TRANSCRIPTION, Ribosomal/genetics, ACTS, Promoter Regions, Genetic, PHOSPHORYLATION, Cells, Cultured, Multidisciplinary, Cultured, Homeodomain Proteins/physiology, Up-Regulation, Chondrocytes/drug effects, Chondrogenesis/drug effects, embryonic structures, Medicine, Chondrogenesis, Transcription, Protein Biosynthesis/drug effects, EXPRESSION, animal structures, Science, Cells, RUNX2, Transcription Factors/physiology, Core Binding Factor Alpha 1 Subunit/genetics, Promoter Regions, Chondrocytes, UBF, Humans, ARTICULAR CHONDROCYTES, Promoter Regions, Genetic/drug effects, Cell Proliferation, Homeodomain Proteins, Genetic/drug effects, GENE-TRANSCRIPTION, urogenital system, REPRESSION, DNA, RNA, Ribosomal/genetics, Bone Morphogenetic Protein 7/pharmacology, RNA, Ribosomal, Protein Biosynthesis, RNA, Transcription Factors
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2
المؤلفون: Cécile Vincke, Marylène Vandevenne, Changxiao Liu, Serge Muyldermans, Yaozhong Hu, Ema Romão, Yvon Elkrim, Lea Brys
المساهمون: Department of Bio-engineering Sciences, Cellular and Molecular Immunology, Faculty of Sciences and Bioengineering Sciences
المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12335, p 12335 (2021)
Volume 22
Issue 22مصطلحات موضوعية: Phage display, Transcription, Genetic, Uterine Cervical Neoplasms, Down-Regulation/drug effects, Hypoxia-Inducible Factor 1, alpha Subunit/antagonists & inhibitors, Intrabody, Transcription, Genetic/drug effects, Transcription (biology), Transcriptional regulation, Biology (General), Spectroscopy, biology, Chemistry, General Medicine, Uterine Cervical Neoplasms/genetics, nanobodies, Cell Hypoxia, Computer Science Applications, Cell biology, Gene Expression Regulation, Neoplastic, Female, QH301-705.5, Immunoprecipitation, Protein subunit, HIF-1α, Down-Regulation, Transfection, Catalysis, Article, Inorganic Chemistry, Downregulation and upregulation, Protein Domains, Escherichia coli, transcriptional activation, Humans, Physical and Theoretical Chemistry, QD1-999, Molecular Biology, Gene, Cell Hypoxia/genetics, Single-Domain Antibodies/genetics, Organic Chemistry, Single-Domain Antibodies, Hypoxia-Inducible Factor 1, alpha Subunit, target genes, Escherichia coli/genetics, Hela Cells, biology.protein, Protein Domains/genetics
وصف الملف: application/pdf
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3Academic Journal
المؤلفون: Cederquist, E
المصدر: Medicinsk Vetenskap vid Karolinska Institutet. (3):21
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4Academic Journal
المؤلفون: Traverso, Juan M, Donnay, Isabelle, Lequarré, Anne-Sophie
المصدر: Molecular Reproduction and Development, 71 (1), 107-14 (2005)
مصطلحات موضوعية: Animals, Cattle, Cell Nucleus/drug effects/metabolism, Cells, Cultured, Cyclin A/metabolism, Cyclin B/genetics/metabolism, Deoxyadenosines/pharmacology, Female, Kinetics, Meiosis/drug effects, Oocytes/cytology/drug effects/metabolism, Poly A/genetics, Polyadenylation/drug effects, Transcription, Genetic/drug effects/genetics, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire
Relation: urn:issn:1040-452X; urn:issn:1098-2795
URL الوصول: https://orbi.uliege.be/handle/2268/12625
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5Academic Journal
المؤلفون: Stavreva, Diana A, Garcia, David A, Fettweis, Grégory, Gudla, Prabhakar R, Zaki, George F, Soni, Vikas, McGowan, Andrew, Williams, Geneva, Huynh, Anh, Palangat, Murali, Schiltz, R Louis, Johnson, Thomas A, Presman, Diego M, Ferguson, Matthew L, Pegoraro, Gianluca, Upadhyaya, Arpita, Hager, Gordon L
المصدر: Molecular Cell, 75 (6), 1161 - 1177.e11 (2019-09-19)
مصطلحات موضوعية: 3D orbital tracking, RNA synthesis, bursting kinetics, circadian cycle, glucocorticoid receptor, high-throughput imaging, single cell, single molecule tracking, transcription dynamics, ultradian hormone stimulation, Glucocorticoids, Receptors, Glucocorticoid, RNA, Animals, Glucocorticoids/pharmacology, Mice, RNA/biosynthesis, RNA/genetics, Receptors, Glucocorticoid/metabolism, Transcription, Genetic/drug effects, Promoter Regions, Genetic, Transcription Initiation Site, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire
Relation: urn:issn:1097-2765; urn:issn:1097-4164
URL الوصول: https://orbi.uliege.be/handle/2268/303033
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المؤلفون: Poon, Evon, Liang, Tong, Jamin, Yann, Walz, Susanne, Kwok, Colin, Hakkert, Anne, Barker, Karen, Urban, Zuzanna, Thway, Khin, Zeid, Rhamy, Hallsworth, Albert, Box, Gary, Ebus, Marli E, Licciardello, Marco P, Sbirkov, Yordan, Lazaro, Glori, Calton, Elizabeth, Costa, Barbara M, Valenti, Melanie, De Haven Brandon, Alexis, Webber, Hannah, Tardif, Nicolas, Almeida, Gilberto S, Christova, Rossitza, Boysen, Gunther, Richards, Mark W, Barone, Giuseppe, Ford, Anthony, Bayliss, Richard, Clarke, Paul A, De Bono, Johann, Gray, Nathanael S, Blagg, Julian, Robinson, Simon P, Eccles, Suzanne A, Zheleva, Daniella, Bradner, James E, Molenaar, Jan, Vivanco, Igor, Eilers, Martin, Workman, Paul, Lin, Charles Y, Chesler, Louis, UU BETA RESEARCH
المساهمون: UU BETA RESEARCH
المصدر: Journal of Clinical Investigation, 130(11), 5875. The American Society for Clinical Investigation
The Journal of Clinical Investigationمصطلحات موضوعية: 0301 basic medicine, Translation, Adenosine, Transcription, Genetic, N-Myc Proto-Oncogene Protein/biosynthesis, Transcription, Genetic/drug effects, Neuroblastoma, 0302 clinical medicine, Gene expression, Positive Transcriptional Elongation Factor B, Cancer, N-Myc Proto-Oncogene Protein, Tumor, biology, Chemistry, General Medicine, Enhancer Elements, Genetic, Oncology, 030220 oncology & carcinogenesis, Positive Transcriptional Elongation Factor B/genetics, Transcription, Research Article, medicine.drug, Enhancer Elements, Cyclin-Dependent Kinase 2/antagonists & inhibitors, Cell Line, 03 medical and health sciences, Genetic, Cyclin-Dependent Kinase 9/antagonists & inhibitors, Cell Line, Tumor, Temozolomide, medicine, Humans, Neuroblastoma/drug therapy, Enhancer, Transcription factor, neoplasms, Genetic/drug effects, Cyclin-Dependent Kinase 2, Cyclin-dependent kinase 2, Temozolomide/pharmacology, medicine.disease, Cyclin-Dependent Kinase 9, Pediatric cancer, 030104 developmental biology, Apoptosis, Cancer research, biology.protein, Adenosine/analogs & derivatives
وصف الملف: application/pdf
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المؤلفون: Peter L. Hordijk, Igor Kovacevic, Saskia Scheij, Emma C. L. Cook, Noam Zelcer, Jessica K. Nelson, Anke Loregger, Huib Ovaa, Marten A. Hoeksema
المساهمون: Graduate School, Medical Biochemistry, ACS - Diabetes & metabolism, ACS - Atherosclerosis & ischemic syndromes, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Gastroenterology Endocrinology Metabolism, Landsteiner Laboratory, AII - Inflammatory diseases, Physiology, ICaR - Ischemia and repair
المصدر: Journal of biological chemistry, 291(9), 4813-4825. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 291(9), 4813-4825. American Society for Biochemistry and Molecular Biology Inc.
Nelson, J K, Cook, E C L, Loregger, A, Hoeksema, M A, Scheij, S, Kovacevic, I, Hordijk, P L, Ovaa, H & Zelcer, N 2016, ' Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake ', Journal of Biological Chemistry, vol. 291, no. 9, pp. 4813-4825 . https://doi.org/10.1074/jbc.M115.698688مصطلحات موضوعية: 0301 basic medicine, Ubiquitin-Specific Proteases/antagonists & inhibitors, Transcription, Genetic, LDL/metabolism, Recombinant Proteins/chemistry, Biochemistry, Transcription, Genetic/drug effects, Mice, Ubiquitin, Genes, Reporter, Orphan Nuclear Receptors/genetics, Receptors, Transcriptional regulation, Receptors, LDL/genetics, Enzyme Inhibitors, Promoter Regions, Genetic, Ubiquitin-Protein Ligases/chemistry, Cells, Cultured, Liver X Receptors, Enzyme Inhibitors/pharmacology, Cultured, biology, Ubiquitination/drug effects, Recombinant Fusion Proteins/chemistry, Orphan Nuclear Receptors, Lipids, Recombinant Proteins, Ubiquitin ligase, Absorption, Physiological, Lipoproteins, LDL, Physiological/drug effects, lipids (amino acids, peptides, and proteins), Ubiquitin-Specific Proteases, Transcription, Absorption, Physiological/drug effects, Lysosomes/drug effects, Recombinant Fusion Proteins, Ubiquitin-Protein Ligases, Cells, Lipoproteins, Human Umbilical Vein Endothelial Cells/cytology, LDL/genetics, Absorption, Cell Line, Promoter Regions, 03 medical and health sciences, Lipoproteins, LDL/metabolism, Human Umbilical Vein Endothelial Cells, Animals, Humans, Liver X receptor, Molecular Biology, Post-transcriptional regulation, Transcription factor, Promoter Regions, Genetic/drug effects, Reporter, Genetic/drug effects, Ubiquitination, Proteolysis/drug effects, Cell Biology, 030104 developmental biology, Nuclear receptor, Receptors, LDL, Amino Acid Substitution, Genes, LDL receptor, Proteolysis, Mutation, biology.protein, Lysosomes
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8
المؤلفون: Stéphanie Dabo, Christine Neuveut, Vincent Lacoste, Marie-Claude Lise, Eliane F. Meurs, Anne Lavergne, Sarkis Sarkis
المساهمون: Laboratoire des Interactions Virus-Hôtes [Cayenne, Guyane Française], Institut Pasteur de la Guyane, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Hépacivirus et Immunité innée, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), This study was conducted within the CAROLIA and BATIMMUNE programs. CAROLIA was supported by European funds (ERDF/FEDER, 31575) and assistance from the Région Guyane and the Direction Régionale pour la Recherche et la Technologie. BATIMMUNE was funded by the Institut Pasteur through a Transversal Research Program (PTR499). This study also received a European Commission 'REGPOT-CT-2011-285837-STRonGer' grant within the FP7 and an 'Investissement d’Avenir' grant managed by the Agence Nationale de la Recherche (CEBA, Ref. ANR-10-LABEX-25-01)., ANR-10-LABX-0025,CEBA,CEnter of the study of Biodiversity in Amazonia(2010), European Project: 285837,EC:FP7:REGPOT,FP7-REGPOT-2011-1,STRONGER(2011), Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris]
المصدر: Developmental and Comparative Immunology
Developmental and Comparative Immunology, 2018, 85, pp.95-107. ⟨10.1016/J.DCI.2018.04.006⟩
Developmental and Comparative Immunology, Elsevier, 2018, 85, pp.95-107. ⟨10.1016/J.DCI.2018.04.006⟩مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Adenosine Deaminase, [SDV]Life Sciences [q-bio], MESH: Antiviral Agents/pharmacology, MESH: Virus Diseases/genetics, ISGs, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, eIF-2 Kinase, Interferon, Transcription (biology), Chiroptera, 2',5'-Oligoadenylate Synthetase, MESH: Animals, Innate immunity, MESH: Transcription, Genetic/drug effects, MESH: Transcription, Genetic/genetics, PKR, MESH: Adenosine Deaminase/genetics, 3. Good health, PKR 20, Virus Diseases, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, medicine.drug, Immunology, Biology, Desmodus rotundus, Antiviral Agents, OAS1a, OAS1b, Cell Line, 03 medical and health sciences, MESH: Poly I-C/genetics, ADAR1, MESH: Chiroptera/genetics, medicine, MESH: 2',5'-Oligoadenylate Synthetase/genetics, Animals, Gene, MESH: eIF-2 Kinase/genetics, Innate immune system, 030102 biochemistry & molecular biology, MESH: Interferons/pharmacology, biology.organism_classification, Virology, Protein kinase R, MESH: Cell Line, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics, 030104 developmental biology, Poly I-C, Cell culture, Vampire bat, Interferons, Developmental Biology
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9Academic Journal
المؤلفون: Fish, Jason E., Cantu Gutierrez, Manuel, Dang, Lan T., Khyzha, Nadiya, Chen, Zhiqi, Veitch, Shawn, Cheng, Henry S., Khor, Melvin, Antounians, Lina, Njock, Makon-Sébastien, Boudreau, Emilie, Herman, Alexander M., Rhyner, Alexander M., Ruiz, Oscar E., Eisenhoffer, George T., Medina-Rivera, Alejandra, Wilson, Michael D., Wythe, Joshua D.
المصدر: Development, 144 (13), 2428-2444 (2017-07-01)
مصطلحات موضوعية: Animals, Cattle, E1A-Associated p300 Protein/metabolism, Enhancer Elements, Genetic/genetics, Extracellular Signal-Regulated MAP Kinases/metabolism, Female, Gene Expression Regulation/drug effects, Gene Expression Regulation, Developmental/drug effects, Gene Regulatory Networks/drug effects, Human Umbilical Vein Endothelial Cells/drug effects/metabolism, Humans, Intercellular Signaling Peptides and Proteins/metabolism, Introns/genetics, MAP Kinase Signaling System/drug effects, Male, Mice, Neovascularization, Physiologic/genetics, Transcription, Genetic/drug effects, Transcriptional Regulator ERG/metabolism, Vascular Endothelial Growth Factor A/pharmacology, Zebrafish/embryology, Angiogenesis, ETS factor, Endothelial cell, Enhancer, Genome editing, Human, Mouse, Transcription, Zebrafish, Life sciences, Genetics & genetic processes, Sciences du vivant, Génétique & processus génétiques
Relation: urn:issn:0950-1991; urn:issn:1477-9129
URL الوصول: https://orbi.uliege.be/handle/2268/217787
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10
المصدر: Cellular Signalling
Cellular Signalling, 36, 240-254. Elsevier Scienceمصطلحات موضوعية: RNA, Messenger/genetics, 0301 basic medicine, MAPK/ERK pathway, Male, Act D, actinomycin D, Transcription, Genetic, β-MHC, myosin heavy chain, β isoform, ANF, atrial natriuretic factor, Wistar, Up-Regulation/drug effects, Gene Expression Regulation/drug effects, Phenylephrine/pharmacology, BNP, brain natriuretic factor, Transcription, Genetic/drug effects, Phenylephrine, Signal Transduction/drug effects, Myocyte, Myocytes, Cardiac, Endothelin A/metabolism, Receptor, Endothelin-1, Cardiac hypertrophy, Signalling, MAPK, GPCRs, DN β-Arr1, dominant negative β-arrestin-1, PE, phenylepherine, ECE, endothelin converting enzyme, Receptor, Endothelin A, Cardiomegaly/genetics, Cell biology, Up-Regulation, NFAT, nuclear factor of activated T cells, NRVMs, neonatal rat ventricular myocytes, DPM, disintegrations per minute, TAC, transverse aortic constriction, Endothelin receptor, ETA receptor, endothelin type A receptor, Transcription, Signal Transduction, Agonist, ECC, excitation contraction coupling, Myocytes, Cardiac/drug effects, medicine.medical_specialty, medicine.drug_class, Cardiomegaly, Biology, CVD, cardiovascular disease, Endocytosis, TCA, trichloroacetic acid, Article, CN, calcineurin, MEF2, myocyte enhancer factor-2, 03 medical and health sciences, Internal medicine, medicine, ET-1, endothelin-1, Animals, Humans, DUSP6, dual specificity phosphatase-6, RNA, Messenger, Rats, Wistar, Protein Kinase Inhibitors, G protein-coupled receptor, IEG, immediate early gene, Receptor, Endothelin A/metabolism, Ang II, angiotensin II, α-MHC, myosin heavy chain, α isoform, Myocytes, Genetic/drug effects, ETB receptor, endothelin type B receptor, Cell Biology, Newborn, Endothelin 1, SRF, serum response factor, ERK1/2, extracellular signal-regulated kinase 1/2, Rats, 030104 developmental biology, Endocrinology, GPCR, G-protein coupled receptor, HEK293 Cells, Cardiac/drug effects, Animals, Newborn, Gene Expression Regulation, Protein Kinase Inhibitors/pharmacology, RNA, Messenger/genetics, Endothelin-1/pharmacology, ara-C, cytosine b-d-arabinofuranoside, PD, PD184352, MAPK, mitogen activated protein kinase
وصف الملف: Print-Electronic; application/pdf
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المؤلفون: Tamas L. Horvath, Maria Teresa Dell’Anno, Xiao-Bing Gao, Naoki Nakagawa, Anze Testen, Yalan Zhang, Tianliuyun Gao, Mihovil Pletikos, Candace Bichsel, Nenad Sestan, Mingfeng Li, Sirisha Pochareddy, Brett D. Lindenbach, Leonard K. Kaczmarek, Zhen Li, Wenqi Han, Forrest O. Gulden, Fuchen Liu, André M. M. Sousa, Stephen M. Strittmatter, Andrew T.N. Tebbenkamp, Marco Onorati, Steven Lisgo, Jernej Mlakar, Marie Flamand, Mara Popović, Eva S. Anton, Luis Varela, Klara Szigeti-Buck, Ying Zhu
المساهمون: Department of Neuroscience [New Haven], Yale University School of Medicine-Kavli Institute for Neuroscience [New Haven], Department of Cell Biology and Physiology, University of North Carolina [Chapel Hill] (UNC), University of North Carolina System (UNC)-University of North Carolina System (UNC), Cellular Neuroscience, Neurodegeneration and Repair Program, Departments of Neurology and Neuroscience [New Haven], Yale University School of Medicine, Section of Comparative Medicine [New Haven], Institute of Genetic Medicine, Newcastle University [Newcastle], Departments of pharmacology and molecular biophysics and biochemistry [New Haven], University of Ljubljana, Département de Virologie - Department of Virology, Institut Pasteur [Paris], Departments of Internal Medicine, Cellular & Molecular Physiology, Departments of Medicine and Cell Biology & Physiology, Department of Microbial Pathogenesis, Reproductive Neuroscience Unit, Department of Obstetrics and Gynecology and Department of Neurobiology, Yale Program in Integrative Cell Signaling and Neurobiology of Metabolism, Kavli Institute for Neuroscience [New Haven], Departments of Psychiatry and Genetics, This work was supported by grants NS076503, MH103339, MH105972, MH106934, MH060929, NS080388, AG034924, AG047270, DC01919, AI120113, and AI089826 from the NIH, SFARI 307705 from the Simons Foundation, and 15-RMA-YALE-31 from Connecticut Innovations’ Regenerative Medicine Research Fund. The Laboratory of Developmental Biology at the University of Washington, Seattle, and Human Developmental Biology Resource were supported by NIH award number HD0008836 and the Joint MRC/Wellcome Trust grant 099175/Z/12/Z, respectively. Additional support was provided by the Kavli Foundation and the Falk Medical Research Trust., Department of Neuroscience, Yale University School of Medicine, Yale School of Medicine [New Haven, Connecticut] (YSM), Institut Pasteur [Paris] (IP), Kavli Institute for Neuroscience, Yale School of Medicine, Yale School of Medicine [New Haven, Connecticut] (YSM)-Yale School of Medicine [New Haven, Connecticut] (YSM)
المصدر: Cell Reports
Cell Reports, Elsevier Inc, 2016, 16 (10), pp.2576-2592. ⟨10.1016/j.celrep.2016.08.038⟩
Cell Reports, 2016, 16 (10), pp.2576-2592. ⟨10.1016/j.celrep.2016.08.038⟩
Cell Reports, Vol 16, Iss 10, Pp 2576-2592 (2016)مصطلحات موضوعية: Genetics and Molecular Biology (all), Microcephaly, Transcription, Genetic, Neocortex, MESH: Neuroepithelial Cells/ultrastructure, Biochemistry, environment and public health, MESH: Brain/virology, Neural Stem Cells, MESH: Centrosome/drug effects, MESH: Mitochondria/metabolism, lcsh:QH301-705.5, Neurons, MESH: Protein-Serine-Threonine Kinases/metabolism, Zika Virus Infection, Brain, MESH: Neurons/virology, MESH: Neural Stem Cells/virology, MESH: Neural Stem Cells/immunology, Nucleosides, MESH: Zika Virus/physiology, MESH: Virus Replication/drug effects, Neural stem cell, 3. Good health, Cell biology, Neuroepithelial cell, MESH: Brain/pathology, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Spinal Cord, MESH: Neocortex/pathology, MESH: Neuroepithelial Cells/immunology, Neuroglia, MESH: Receptor Protein-Tyrosine Kinases/metabolism, Article, General Biochemistry, Genetics and Molecular Biology, MESH: Protein Kinase Inhibitors/pharmacology, 03 medical and health sciences, MESH: Gene Expression Profiling, Fetus, Humans, MESH: Phosphorylation/drug effects, Mitosis, MESH: Neural Stem Cells/ultrastructure, Biochemistry, Genetics and Molecular Biology (all), MESH: Humans, Receptor Protein-Tyrosine Kinases, MESH: Zika Virus/pathogenicity, medicine.disease, Immunity, Innate, MESH: Mitosis/drug effects, 030104 developmental biology, MESH: Neuroprotective Agents/pharmacology, MESH: Mitochondria/drug effects, MESH: Spinal Cord/pathology, MESH: Neuroglia/ultrastructure, 0301 basic medicine, MESH: Fetus/virology, viruses, [SDV]Life Sciences [q-bio], Neuroepithelial Cells, MESH: Zika Virus/ultrastructure, Virus Replication, MESH: Neurons/drug effects, MESH: Neuroepithelial Cells/drug effects, MESH: Zika Virus Infection/pathology, MESH: Neurons/pathology, MESH: Immunity, Innate/drug effects, Phosphorylation, Genetics, Cell Death, MESH: Transcription, Genetic/drug effects, MESH: Neuroglia/virology, MESH: Nucleosides/pharmacology, Mitochondria, Neuroprotective Agents, MESH: Neuroglia/pathology, lipids (amino acids, peptides, and proteins), MESH: Zika Virus Infection/virology, Stem cell, Programmed cell death, MESH: Centrosome/metabolism, MESH: Brain/embryology, Protein Serine-Threonine Kinases, Biology, Proto-Oncogene Proteins, MESH: Microcephaly/pathology, medicine, MESH: Zika Virus/drug effects, Protein Kinase Inhibitors, Centrosome, MESH: Neural Stem Cells/enzymology, Gene Expression Profiling, MESH: Proto-Oncogene Proteins/metabolism, Zika Virus, Axl Receptor Tyrosine Kinase, MESH: Microcephaly/virology, Gene expression profiling, MESH: Cell Death/drug effects, lcsh:Biology (General), MESH: Neuroepithelial Cells/virology
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المؤلفون: Sarah Labib, Andrew Williams, Håkan Wallin, Sabina Halappanavar, Carole L. Yauk, Jake K. Nikota, Ulla Vogel
المصدر: Particle and Fibre Toxicology
Labib, S, Williams, A, Yauk, C L, Nikota, J K, Wallin, H, Vogel, U & Halappanavar, S 2016, ' Nano-risk Science : application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes ', Particle and Fibre Toxicology, vol. 13, 15 . https://doi.org/10.1186/s12989-016-0125-9
Labib, S, Williams, A, Yauk, C L, Nikota, J K, Wallin, H, Vogel, U B & Halappanavar, S 2016, ' Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes ', Particle and Fibre Toxicology, vol. 13, no. 1 . https://doi.org/10.1186/s12989-016-0125-9مصطلحات موضوعية: 0301 basic medicine, Adverse outcome pathways, Male, Time Factors, Transcription, Genetic, Health, Toxicology and Mutagenesis, Pulmonary Fibrosis, Engineered nanomaterials, Gene regulatory network, Gene Expression Regulation/drug effects, 02 engineering and technology, Pharmacology, Toxicology, Toxicogenetics, Transcription, Genetic/drug effects, Mice, Adverse Outcome Pathway, Databases, Genetic, Nanotechnology, Gene Regulatory Networks, Lung, Oligonucleotide Array Sequence Analysis, Lung fibrosis, General Medicine, Nano, 021001 nanoscience & nanotechnology, Toxicogenomics, Benchmarking, Nanotubes, Carbon/toxicity, 0210 nano-technology, Risk assessment, Case study, Computational biology, Biology, Risk Assessment, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Gene Regulatory Networks/drug effects, Animals, Humans, Benchmark dose, Lung/drug effects, Dose-Response Relationship, Drug, Nanotubes, Carbon, Research, Gene Expression Profiling, Pulmonary Fibrosis/chemically induced, Computational Biology, Gene expression profiling, 030104 developmental biology, Gene Expression Regulation, Gene Expression Profiling/methods
وصف الملف: application/pdf
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المؤلفون: Francesca Frigerio, Søren Fisker Schmidt, Lars la Cour Poulsen, Pierre Maechler, Michael Boergesen, Susanne Mandrup
المصدر: The Journal of biological chemistry
Boergesen, M, Poulsen, L L C, Schmidt, S F, Frigerio, F, Maechler, P & Mandrup, S 2011, ' ChREBP Mediates Glucose Repression of Peroxisome Proliferator-activated Receptor {alpha} Expression in Pancreatic {beta}-Cells ', Journal of Biological Chemistry, vol. 286, no. 15, pp. 13214-13225 . https://doi.org/10.1074/jbc.M110.215467
Journal of Biological Chemistry, Vol. 286, No 15 (2011) pp. 13214-25مصطلحات موضوعية: Exons/physiology, Transcription, Genetic, Peroxisome proliferator-activated receptor, Transcription Factors/genetics/metabolism, Biochemistry, Mice, 0302 clinical medicine, Insulin-Secreting Cells, Gene expression, Sweetening Agents/metabolism/pharmacology, Repressor Proteins/genetics/metabolism, Transcription, Genetic/drug effects/physiology, chemistry.chemical_classification, Regulation of gene expression, 0303 health sciences, Gene knockdown, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Fatty Acids, Fatty Acids/genetics/metabolism, Nuclear Proteins, Exons, 3. Good health, medicine.anatomical_structure, Gene Knockdown Techniques, Insulin-Secreting Cells/cytology/metabolism, Oxidation-Reduction, medicine.medical_specialty, 030209 endocrinology & metabolism, Biology, Carbohydrate metabolism, 03 medical and health sciences, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/genetics/metabolism, Cell Line, Tumor, Internal medicine, medicine, Animals, Humans, Nuclear Proteins/genetics/metabolism, Gene Regulation, PPAR alpha, Gene Expression Regulation/drug effects/physiology, Rats, Wistar, ddc:612, Carbohydrate-responsive element-binding protein, Molecular Biology, Transcription factor, 030304 developmental biology, Pancreatic islets, Cell Biology, Protein Structure, Tertiary, Rats, Repressor Proteins, Glucose, HEK293 Cells, Endocrinology, Gene Expression Regulation, chemistry, Sweetening Agents, Glucose/metabolism/pharmacology, PPAR alpha/biosynthesis/genetics, Transcription Factors
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المؤلفون: Nakatsu, Y., Sakoda, H., Kushiyama, A., Ono, H., Fujishiro, M., Horike, N., Yoneda, M., Ohno, H., Tsuchiya, Y., Kamata, H., Tahara, H., Isobe, T., Nishimura, F., Katagiri, H., Oka, Y., Fukushima, Toshiaki, Takahashi, S., Kurihara, H., Uchida, T., Asano, T.
المصدر: The Journal of Biological Chemistry. 285(43):33018-33027
مصطلحات موضوعية: Cytosol/metabolism, Transcription, Genetic, Cyclic AMP/*metabolism, Colforsin/pharmacology, Nuclear Localization Signals, Transcription Factors/genetics/*metabolism, Cell Nucleus/genetics/*metabolism, Trans-Activators/genetics/*metabolism, Biochemistry, Mice, Cytosol, Cyclic AMP, Cyclic AMP Response Element-Binding Protein, Transcription, Genetic/drug effects/*physiology, Gene knockdown, Cyclic AMP Response Element-Binding Protein/genetics/metabolism, Peptidylprolyl Isomerase/genetics/*metabolism, biology, Hep G2 Cells, Peptidylprolyl Isomerase, CREB-Binding Protein, CRTC1, CRTC2, medicine.anatomical_structure, Liver, Gene Knockdown Techniques, PIN1, Liver/metabolism, phosphoenolpyruvate carboxykinase (PEPCK), Active Transport, Cell Nucleus/drug effects/physiology, Active Transport, Cell Nucleus, CREB, Pin1, medicine, Animals, Humans, CREB-binding protein, Molecular Biology, Transcription factor, Cell Nucleus, CREB-Binding Protein/genetics/metabolism, Colforsin, Nuclear Localization Signals/genetics/*metabolism, Cell Biology, Molecular biology, NIMA-Interacting Peptidylprolyl Isomerase, Cell nucleus, Metabolism, cAMP responsive element (CRE), biology.protein, Trans-Activators, Nuclear localization sequence, Transcription Factors
وصف الملف: application/pdf
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15
المؤلفون: Pierre Maechler, Valeria Grasso, Fabrizio Barbetti, Massimo Alessio, Valentina D'Oria, Sara Sileno, Ornella Massa, Stefania Petrini, Federico Bertuzzi, Katia Paolella, Valentina Bonetto, Riccardo Stucchi
المصدر: Journal of Proteomics, Vol. 96 (2014) pp. 314-327
Journal of Proteomicsمصطلحات موضوعية: Heterogeneous nuclear ribonucleoprotein, Calcium/metabolism, Transcription, Genetic, Tissue transglutaminase, G protein, medicine.medical_treatment, INS-1E, Barrier-to-autointegration factor, Biophysics, FPIS, first phase insulin secretion, Biochemistry, Article, Histone H3, TG2, transglutaminase 2, GTP-Binding Proteins, Insulin-Secreting Cells, Cell Line, Tumor, medicine, Insulin, Animals, Humans, Protein Glutamine gamma Glutamyltransferase 2, Sweetening Agents/pharmacology, Cell Nucleus/enzymology, Nuclear protein, Insulin-Secreting Cells/cytology/enzymology, Calcium concentration, Cell Nucleus, ddc:616, Insulin/secretion, Transcription, Genetic/drug effects/physiology, Human islet, Transglutaminases, biology, Insulin secretion, Glucose/pharmacology, Rats, Transglutaminase 2, Cell nucleus, Glucose, medicine.anatomical_structure, Sweetening Agents, biology.protein, Transglutaminases/genetics/metabolism, Calcium, β-Cell
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16
المؤلفون: Darina Ocadlikova, Cecilia Evangelisti, Marilena Ciciarello, Mariangela Lecciso, Pedro Romero, Sara Trabanelli, Roberto M. Lemoli, George C. Prendergast, Richard P. Metz, Lisa Laury-Kleintop, Antonio Curti, Valentina Salvestrini, Camilla Jandus
المساهمون: Trabanelli S, Očadlíková D, Ciciarello M, Salvestrini V, Lecciso M, Jandus C, Metz R, Evangelisti C, Laury-Kleintop L, Romero P, Prendergast GC, Curti A, Lemoli RM.
المصدر: Journal of Immunology
Journal of Immunology, vol. 192, no. 3, pp. 1231-1240مصطلحات موضوعية: Myeloid, Transcription, Genetic, Immunology, Suppressor of Cytokine Signaling Proteins, Dendric cell, Biology, T-Lymphocytes, Regulatory, Dinoprostone, Monocytes, Article, Immune tolerance, Proinflammatory cytokine, IDO, Arthritis, Rheumatoid, Immune system, Downregulation and upregulation, RNA interference, medicine, Immune Tolerance, Immunology and Allergy, Homeostasis, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Spondylitis, Ankylosing, SOCS3, Enzyme inducer, RNA, Small Interfering, Cells, Cultured, PGE, Arthritis, Psoriatic/immunology, Arthritis, Psoriatic/pathology, Arthritis, Rheumatoid/immunology, Arthritis, Rheumatoid/pathology, Dendritic Cells/classification, Dendritic Cells/enzymology, Dinoprostone/pharmacology, Dinoprostone/physiology, Enzyme Induction/drug effects, Indoleamine-Pyrrole 2,3,-Dioxygenase/biosynthesis, Indoleamine-Pyrrole 2,3,-Dioxygenase/genetics, Monocytes/cytology, Monocytes/drug effects, Organ Specificity, Protein Biosynthesis/drug effects, RNA Interference, RNA, Small Interfering/pharmacology, Spondylitis, Ankylosing/immunology, Spondylitis, Ankylosing/pathology, Suppressor of Cytokine Signaling Proteins/antagonists & inhibitors, T-Lymphocytes, Regulatory/immunology, Transcription, Genetic/drug effects, Tryptophan/metabolism, Up-Regulation/drug effects, Arthritis, Psoriatic, Tryptophan, Dendritic Cells, Up-Regulation, medicine.anatomical_structure, Suppressor of Cytokine Signaling 3 Protein, Enzyme Induction, Protein Biosynthesis, biology.protein
وصف الملف: STAMPA; application/pdf
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17
المؤلفون: François Fuks, Ken Declerck, Guido R.M.M. Haenen, Katarzyna Szarc vel Szic, Martin Bizet, Guy Haegeman, Matthieu Defrance, Antje R. Weseler, Aalt Bast, Christine Leroux, Dragan Milenkovic, Céline Boby, Emilie Calonne, Wim Vanden Berghe, Kris Laukens, Karen Heyninck, Sarah Dedeurwaerder
المساهمون: Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université, Universiteit Gent = Ghent University (UGENT), PPES, Department of Biomedical Sciences, University of Antwerp (UA), Unité Mixte de Recherche sur les Herbivores - UMR 1213 (UMRH), Institut National de la Recherche Agronomique (INRA)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS), Department of Mathematics and Computer Science, Laboratory of Cancer Epigenetics, ULB-Cancer Research Centre, Maastricht University [Maastricht], International Nutrition Company (INC) BV, Loosdrecht, The Netherlands, European Union [226588], University of Antwerp, Belgium, Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université-Institut National de la Recherche Agronomique (INRA), Universiteit Gent = Ghent University [Belgium] (UGENT), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut National de la Recherche Agronomique (INRA)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Farmacologie en Toxicologie, RS: NUTRIM - R3 - Chronic inflammatory disease and wasting, RS: CARIM - R3 - Vascular biology
المصدر: PLoS ONE
PLoS ONE, 2014, 9 (4), pp.e95527. ⟨10.1371/journal.pone.0095527⟩
Plos One 4 (9), e95527. (2014)
PLoS ONE, Public Library of Science, 2014, 9 (4), pp.e95527. ⟨10.1371/journal.pone.0095527⟩
PLOS ONE
PloS one, 9 (4
PLOS ONE, 9(4):e95527. Public Library of Science
PLoS ONE, Vol 9, Iss 4, p e95527 (2014)مصطلحات موضوعية: Male, Transcription, Genetic, Microarrays, BLOOD MONONUCLEAR-CELLS, DISEASE, 0302 clinical medicine, Animal Cells, Transcription (biology), Gene expression, mécanisme, lcsh:Science, Immune Response, Cells, Cultured, Oligonucleotide Array Sequence Analysis, 0303 health sciences, NF-kappa B, food and beverages, Genomics, Sciences bio-médicales et agricoles, 3. Good health, FACTOR-KAPPA-B, Bioassays and Physiological Analysis, EPIGENETIC MECHANISMS, Cardiovascular Diseases, 030220 oncology & carcinogenesis, Epigenetics, Flavonoids -- administration & dosage, Cellular Types, Grape Seed Extract -- administration & dosage, SMOKING, Immune Cells, Immunology, Cardiovascular Diseases -- genetics -- metabolism -- prevention & control, Médecine humaine et pathologie, maladie, 03 medical and health sciences, POLYPHENOLS, épigénétique, adhésion cellulaire, Human Umbilical Vein Endothelial Cells, Genetics, Humans, Biology, Reporter gene, lcsh:R, fungi, Computational Biology, Biology and Life Sciences, Human Umbilical Vein Endothelial Cells -- drug effects -- physiology, DNA Methylation, lcsh:Q, CpG Islands, Human health and pathology, Human medicine, lcsh:Medicine, Gene Expression, Leukocytes -- metabolism, EXPRESSION PROFILES, Molecular Cell Biology, Leukocytes, Medicine and Health Sciences, NF-kappa B -- metabolism, profil d'expression, cellule endotheliale vasculaire, Multidisciplinary, Middle Aged, Clinical Laboratory Sciences, DNA methylation, DNA microarray, Transcriptome Analysis, Engineering sciences. Technology, nf kappa b, Research Article, Adult, Transcription, Genetic -- drug effects, Cardiology, LEUKOCYTE ADHESION, Research and Analysis Methods, polyphénol, Diagnostic Medicine, échantillon sanguin, Cell Adhesion, leucocyte, Transcription factor, Gene, Nutrition, 030304 developmental biology, Flavonoids, Grape Seed Extract, Cell Biology, Sequence Analysis, DNA, Genome Analysis, Molecular biology, ENDOTHELIAL-CELLS, Coculture Techniques, Gene Expression Regulation, PATTERNS, Clinical Immunology, Genome Expression Analysis, Transcriptome, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, cellule mononuclee
وصف الملف: application/pdf; 1 full-text file(s): application/pdf; pdf
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18Academic Journal
المؤلفون: Frizzell, C, Ndossi, D, Verhaegen, S, Dahl, E, Eriksen, G, Sorlie, M, Ropstad, E, Muller, Marc, Elliott, C T, Connolly, L
المصدر: Toxicology Letters, 206 (2), 210-217 (2011)
مصطلحات موضوعية: Cell Line, Cell Survival/drug effects, Endocrine Disruptors/chemistry/metabolism/toxicity, Estrogens, Non-Steroidal/chemistry/metabolism/toxicity, Genes, Reporter/drug effects, Gonadal Steroid Hormones/metabolism, Humans, Hydrocortisone/metabolism, Inhibitory Concentration 50, Isomerism, Osmolar Concentration, Promoter Regions, Genetic/drug effects, Receptors, Steroid/agonists/antagonists & inhibitors/genetics/metabolism, Signal Transduction/drug effects, Transcription, Genetic/drug effects, Zearalenone/metabolism/toxicity, Zeranol/analogs & derivatives/chemistry/toxicity, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire
Relation: urn:issn:0378-4274; urn:issn:1879-3169
URL الوصول: https://orbi.uliege.be/handle/2268/122015
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المؤلفون: Mira, N.P., Becker, J.D., Sa-Correia, I.
المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAPمصطلحات موضوعية: Gene Expression Regulation, Fungal/drug effects, Gene Regulatory Networks/drug effects, Protein-Serine-Threonine Kinases/genetics, Genome, Fungal/drug effects, Acetic Acid/pharmacology, Transcription, Genetic/drug effects
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المؤلفون: Bruno Chatton, Adonis Hazoume, Marc Vigneron, Claude Kedinger, Kambiz Naderi, Ermanno Candolfi
المصدر: Molecular and biochemical parasitology. 176(2)
مصطلحات موضوعية: Transcription, Genetic, Amino Acid Motifs, Molecular Sequence Data, Plasmodium falciparum, Protozoan Proteins, RNA-dependent RNA polymerase, Recombinant Proteins/*genetics/metabolism, RNA polymerase II, Saccharomyces cerevisiae, Biology, Protozoan Proteins/*genetics/metabolism, RNA polymerase III, Sciences du Vivant [q-bio]/Génétique, Transcription, Genetic/drug effects, Small Molecule Libraries, chemistry.chemical_compound, Transcription (biology), RNA polymerase, Catalytic Domain, parasitic diseases, RNA polymerase I, Humans, Saccharomyces cerevisiae/*genetics/metabolism, Amino Acid Sequence, Enzyme Inhibitors, Malaria, Falciparum, Molecular Biology, Polymerase, Alpha-Amanitin, Enzyme Inhibitors/pharmacology, Sequence Homology, Amino Acid, Genetic Complementation Test, Plasmodium falciparum/drug effects/*genetics/metabolism, Protein Subunits/*genetics/metabolism, Molecular biology, RNA Polymerase II/*genetics/metabolism, Recombinant Proteins, Protein Subunits, chemistry, biology.protein, Mutagenesis, Site-Directed, Parasitology, RNA Polymerase II, Transcription factor II D, Malaria, Falciparum/parasitology