المؤلفون: Edward Hammond, Nicole M. Haynes, Carleen Cullinane, Todd V. Brennan, Darryn Bampton, Paul Handley, Tomislav Karoli, Fleur Lanksheer, Liwen Lin, Yiping Yang, Keith Dredge

المصدر: Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: Pixatimod, PG545, Immunomodulatory, Tumor-associated macrophage, Dendritic cell, NK cell, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40425-018-0363-5; https://doaj.org/toc/2051-1426

URL الوصول: https://doaj.org/article/106a8f435d52440dbe798c490d689297

المؤلفون: Mark A. T. Blaskovich, Karl A. Hansford, Yujing Gong, Mark S. Butler, Craig Muldoon, Johnny X. Huang, Soumya Ramu, Alberto B. Silva, Mu Cheng, Angela M. Kavanagh, Zyta Ziora, Rajaratnam Premraj, Fredrik Lindahl, Tanya A. Bradford, June C. Lee, Tomislav Karoli, Ruby Pelingon, David J. Edwards, Maite Amado, Alysha G. Elliott, Wanida Phetsang, Noor Huda Daud, Johan E. Deecke, Hanna E. Sidjabat, Sefetogi Ramaologa, Johannes Zuegg, Jason R. Betley, Andrew P. G. Beevers, Richard A. G. Smith, Jason A. Roberts, David L. Paterson, Matthew A. Cooper

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/5939bc54d4b347d7b1b16946d6d5c490

المؤلفون: Angie M. Jarrad, Mark A. T. Blaskovich, Anggia Prasetyoputri, Tomislav Karoli, Karl A. Hansford, Matthew A. Cooper

المصدر: Frontiers in Microbiology, Vol 9 (2018)

مصطلحات موضوعية: Clostridium difficile, Eagle effect, vancomycin, antibiotic resistance, ATP-bioluminescence, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmicb.2018.01420/full; https://doaj.org/toc/1664-302X

URL الوصول: https://doaj.org/article/256dd602bd20435ab6cc9b07b2b0eee5

المؤلفون: Vito Ferro, Tomislav Karoli, Jon K. Fairweather, Ligong Liu

المصدر: Molecules, Vol 17, Iss 8, Pp 9790-9802 (2012)

مصطلحات موضوعية: disaccharides, heparan sulfate mimetics, fibroblast growth factors, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/17/8/9790; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/e42e954875c146429b36a2f2a17415a4

المؤلفون: Potential Heparan, Sulfate Mimetics, Jon K. Fairweather, Ligong Liu, Tomislav Karoli, Vito Ferro

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.mdpi.com/1420-3049/17/8/9790/pdf/.

مصطلحات موضوعية: disaccharides, heparan sulfate mimetics, fibroblast growth factors

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.360.9378; http://www.mdpi.com/1420-3049/17/8/9790/pdf/

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.360.9378
http://www.mdpi.com/1420-3049/17/8/9790/pdf/

المؤلفون: Angie M. Jarrad, Mark A. T. Blaskovich, Tomislav Karoli, Mark S. Butler, Chee Wei Ang, Nicholas P. West, Mark E. Cooper, Vicky M. Avery, Melissa Sykes, Kyra Woods, Anjan Debnath, Amy J. Jones, Hye Jee Hahn, Lendl Tan, Ruby Pelingon

المصدر: Journal of Medicinal Chemistry

مصطلحات موضوعية: 0301 basic medicine, Antiparasitic, medicine.drug_class, Antitubercular Agents, Drug Evaluation, Preclinical, Microbial Sensitivity Tests, Pharmacology, 01 natural sciences, Article, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Entamoeba histolytica, Drug Stability, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Nitroimidazole, Antiparasitic Agents, Bicyclic molecule, biology, 010405 organic chemistry, Chemistry, medicine.disease, biology.organism_classification, 0104 chemical sciences, 3. Good health, 030104 developmental biology, Visceral leishmaniasis, Nitroimidazoles, Drug Design, Pretomanid, Microsomes, Liver, Molecular Medicine, Caco-2 Cells, Giardia lamblia, Delamanid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdeebf31546a59be77d3cad28af05e55
https://doi.org/10.1021/acs.jmedchem.8b01578

المؤلفون: Mark A. T. Blaskovich, Tomislav Karoli, Anggia Prasetyoputri, Angie M. Jarrad, Mark E. Cooper, Karl A. Hansford

المصدر: Frontiers in Microbiology
Frontiers in Microbiology, Vol 9 (2018)

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), antibiotic resistance, ATP-bioluminescence, 030106 microbiology, vancomycin, lcsh:QR1-502, Microbiology, lcsh:Microbiology, 03 medical and health sciences, Minimum inhibitory concentration, 0302 clinical medicine, Telavancin, medicine, Methods, Fidaxomicin, 030212 general & internal medicine, Eagle effect, Minimum bactericidal concentration, Chemistry, Teicoplanin, Oritavancin, Clostridium difficile, Vancomycin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b158759dc91c0a9befa27fcf1a946315
http://europepmc.org/articles/PMC6036128

المؤلفون: Mark A. T. Blaskovich, Trpta Bains, Ruby Pelingon, Mark E. Cooper, Anjan Debnath, Karl A. Hansford, Tomislav Karoli, Angie M. Jarrad, Lars Eckmann, Mark S. Butler, Yukiko Miyamoto

المصدر: European Journal of Medicinal Chemistry

مصطلحات موضوعية: 0301 basic medicine, Antiparasitic, medicine.drug_class, 030106 microbiology, Drug Resistance, Drug resistance, Biology, medicine.disease_cause, MtzR, metronidazole resistant, Plasma protein binding, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Entamoeba histolytica, Drug Stability, Drug Discovery, parasitic diseases, medicine, MtzS, metronidazole sensitive, Trichomonas vaginalis, Giardia lamblia, Animals, Humans, Parasites, Cells, Cultured, Pharmacology, Antiparasitic agent, Nitroimidazole, Antiparasitic Agents, Organic Chemistry, General Medicine, biology.organism_classification, 3. Good health, Metronidazole, 030104 developmental biology, Metabolism, chemistry, Nitroimidazoles, MIC, minimum inhibition concentration, medicine.drug, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8c72921b02b2a76eb6ae675522ad10
http://europepmc.org/articles/PMC4920673

المؤلفون: Tomislav Karoli, Andrea Ranzoni, A Anniek den Hamer, Joseph Buechler, Mark E. Cooper

المساهمون: Chemical Biology

المصدر: Analytical Chemistry, 87(12), 6150-6157. American Chemical Society

مصطلحات موضوعية: Analyte, Polymers, Nanoparticle, Nanotechnology, Viral Nonstructural Proteins, SDG 3 – Goede gezondheid en welzijn, Antibodies, Fluorescence, Analytical Chemistry, SDG 3 - Good Health and Well-being, Monoclonal, Quantum Dots, medicine, Humans, Particle Size, Immunoassay, chemistry.chemical_classification, Bioconjugation, medicine.diagnostic_test, Carica, Antibodies, Monoclonal, Polymer, Photobleaching, chemistry, Quantum dot, Fruit, Nanoparticles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8bc28228b9f74ad4b84aac19736424
https://doi.org/10.1021/acs.analchem.5b00762

المؤلفون: Tomislav Karoli, Mark E. Cooper, Angie M. Jarrad, Mark A. T. Blaskovich, Dena Lyras

المصدر: Journal of Medicinal Chemistry

مصطلحات موضوعية: Drug, medicine.medical_specialty, medicine.drug_class, media_common.quotation_subject, Antibiotics, Biology, Microbiology, Drug Discovery, medicine, Humans, Fidaxomicin, Drug pipeline, Intensive care medicine, Enterocolitis, Pseudomembranous, media_common, Enterocolitis, Clostridioides difficile, Gastrointestinal Microbiome, Clostridium difficile, Anti-Bacterial Agents, 3. Good health, Diarrhea, Perspective, Molecular Medicine, medicine.symptom, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5acd79b7c80dc0abf69f7977ac626b
https://doi.org/10.1021/jm5016846

المؤلفون: Ligong Liu, Edward Trybala, Vito Ferro, Tomas Bergström, Maria Ekblad, Beata Adamiak, Tomislav Karoli, Ken D. Johnstone

المصدر: Antiviral Research. 86:196-203

مصطلحات موضوعية: Bodily Secretions, Herpesvirus 2, Human, viruses, Oligosaccharides, Herpesvirus 1, Human, Viral Plaque Assay, Biology, medicine.disease_cause, Antiviral Agents, Virus, Cell Line, Microscopy, Electron, Transmission, Virology, Virucide, Chlorocebus aethiops, medicine, Animals, Humans, Mode of action, Pharmacology, chemistry.chemical_classification, Infectivity, Microbial Viability, Molecular Structure, Glycoside, Oligosaccharide, Herpes simplex virus, chemistry, Biochemistry, Cell culture

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a83dd989143c00adb4d136f679c0658
https://doi.org/10.1016/j.antiviral.2010.02.318

المؤلفون: Cai Ping Li, Jon K. Fairweather, Siska Cochran, Ian Bytheway, Vito Ferro, Tomislav Karoli, Ligong Liu

المصدر: Bioorganic & Medicinal Chemistry Letters. 18:344-349

مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Clinical Biochemistry, Disaccharide, Pharmaceutical Science, Plasma protein binding, Disaccharides, Biochemistry, chemistry.chemical_compound, Sulfation, Biomimetic Materials, Drug Discovery, Carbohydrate Conformation, Binding site, Nuclear Magnetic Resonance, Biomolecular, Molecular Biology, Conformational isomerism, Binding Sites, Xylose, Heparin, Chemistry, Organic Chemistry, Kinetics, Glucose, Docking (molecular), Fibroblast Growth Factor 1, Thermodynamics, Molecular Medicine, Carbohydrate conformation, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1355f94ebe1dfcaa9e08e4c16f5bc7
https://doi.org/10.1016/j.bmcl.2007.10.071

المؤلفون: Anaud Gautam, Ligong Liu, Vito Ferro, Kat Davis, Edward Hammond, Elizabeth Copeman, Cai Ping Li, Keith Dredge, Ken D. Johnstone, Ian Bytheway, Tomislav Karoli

المصدر: Seminars in Thrombosis and Hemostasis. 33:557-568

مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Carcinoma, Hepatocellular, Angiogenesis, Oligosaccharides, Fibroblast growth factor, chemistry.chemical_compound, Biomimetic Materials, Animals, Humans, Heparanase, Neoplasm Metastasis, Cell Proliferation, Tube formation, Matrigel, Neovascularization, Pathologic, Endothelial Cells, Hematology, Heparan sulfate, Vascular endothelial growth factor, Endothelial stem cell, Clinical Trials, Phase III as Topic, Heparin Lyase, Biochemistry, chemistry, Chemotherapy, Adjuvant, Cancer research, Fibroblast Growth Factor 1, Fibroblast Growth Factor 2, Heparitin Sulfate, Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba771d610b4f1b79943eebb7b3ce4fa1
https://doi.org/10.1055/s-2007-982088

المؤلفون: Geraldine Kaeslin, Anjan Debnath, Yukiko Miyamoto, Soumya Ramu, Tomislav Karoli, Alysha G. Elliott, Mark A. T. Blaskovich, Johnny X. Huang, Angie M. Jarrad, Chin Yen Tay, Mark E. Cooper, Johannes Zuegg, Angela M. Kavanagh, Lars Eckmann

المصدر: European Journal of Medicinal Chemistry

مصطلحات موضوعية: chemistry.chemical_compound, Parasitic Sensitivity Tests, Drug Discovery, MtzS, metronidazole sensitive, Antibacterial agent, Nitroimidazole, biology, Antiparasitic Agents, Molecular Structure, Chemistry, Click chemistry, Entamoeba histolytica, General Medicine, Hep G2 Cells, Pharmacology and Pharmaceutical Sciences, Clostridium difficile, Antimicrobial, Mtz, metronidazole, Foodborne Illness, 3. Good health, Anti-Bacterial Agents, Infectious Diseases, Anaerobic bacteria, Drug, Infection, medicine.drug, Research Paper, Cell Survival, Medicinal & Biomolecular Chemistry, Microbial Sensitivity Tests, MtzR, metronidazole resistant, Microbiology, Dose-Response Relationship, Vaccine Related, Structure-Activity Relationship, Medicinal and Biomolecular Chemistry, Metronidazole, Biodefense, parasitic diseases, medicine, Animals, Humans, Parasites, Pharmacology, Dose-Response Relationship, Drug, Clostridioides difficile, Prevention, Organic Chemistry, Antibiotic, Triazoles, biology.organism_classification, Antiparasitic agent, Anaerobe, HEK293 Cells, Emerging Infectious Diseases, MIC, minimum inhibition concentration, Antimicrobial Resistance, Giardia lamblia, Digestive Diseases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1eadec709ea3044fb6cdcf7ed8e7f7a
https://escholarship.org/uc/item/6gf4g1fh

المؤلفون: Tomislav Karoli, Ligong Liu, Jon K. Fairweather, R. S. Addison, Cai Ping Li, Edward Hammond, Kicki Bergefall, Edward Trybala, Vito Ferro, Siska Cochran

المصدر: Journal of Medicinal Chemistry. 48:8229-8236

مصطلحات موضوعية: Blood Platelets, Male, Vascular Endothelial Growth Factor A, Angiogenesis, Oligosaccharides, Angiogenesis Inhibitors, Herpesvirus 1, Human, Antiviral Agents, Rats, Sprague-Dawley, chemistry.chemical_compound, In vivo, Chlorocebus aethiops, Drug Discovery, Animals, Humans, Heparanase, Cells, Cultured, Glucuronidase, biology, Biological activity, Heparan sulfate, Surface Plasmon Resonance, In vitro, Rats, Angiogenesis inhibitor, chemistry, Biochemistry, Enzyme inhibitor, biology.protein, Fibroblast Growth Factor 1, Molecular Medicine, Fibroblast Growth Factor 2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b995c34eb6cd5fbf5b3a24d6ff9d0c
https://doi.org/10.1021/jm050618p

المؤلفون: Mark E. Cooper, Ernest H. L. Tee, Tomislav Karoli, Mark S. Butler, Johnny X. Huang, Soumya Ramu

المصدر: Journal of Natural Products. 73:1940-1942

مصطلحات موضوعية: Pharmacology, Natural product, Molecular Structure, Organic Chemistry, Substituent, Pharmaceutical Science, Biological activity, Microbial Sensitivity Tests, Pyrimidinones, Triazoles, Tautomer, Chemical synthesis, Streptomyces, Anti-Bacterial Agents, Analytical Chemistry, chemistry.chemical_compound, Complementary and alternative medicine, chemistry, Drug Discovery, Molecular Medicine, Organic chemistry, Essramycin, Antibacterial activity, Nuclear Magnetic Resonance, Biomolecular, Antibacterial agent

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a79a11eb3bdb8e92c9a69e7bc0d5d9
https://doi.org/10.1021/np100648q

المؤلفون: Weimin Yue, Curtis F. Crasto, Tomislav Karoli, Lucy Mensah, Peter J. O'Hanlon, Martin G. Banwell, Andrew Keith Forrest, Christopher J. Easton, Darren R. March, Mark D Oldham, Michael R. Nairn

المصدر: Bioorganic & Medicinal Chemistry Letters. 10:2263-2266

مصطلحات موضوعية: Isoleucine-tRNA Ligase, Pyridines, Valine-tRNA Ligase, Stereochemistry, Altemicidin, Isoleucine—tRNA ligase, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, Biochemistry, Structure-Activity Relationship, Alkaloids, Valine, Drug Discovery, Animals, Enzyme Inhibitors, Molecular Biology, Antibacterial agent, Sulfonamides, Bacteria, Sulfur Compounds, Chemistry, Organic Chemistry, Leucine—tRNA ligase, Anti-Bacterial Agents, Rats, Kinetics, Valine—tRNA ligase, Indenes, Liver, Drug Design, Molecular Medicine, Leucine, Isoleucine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fe42692b2c50e0abba9da248d7f574
https://doi.org/10.1016/s0960-894x(00)00456-x

المؤلفون: Tee, Ernest H. L., Tomislav Karoli, Ramu, Soumya, Huang, Johnny X., Butler, Mark S., Cooper, Matthew A.

مصطلحات موضوعية: Antimicrobial Evaluation, Tautomerism, Derivatives, Substituent, Inhibitors, Agents, Mice, Sar, 1313 Molecular Medicine, 1602 Analytical Chemistry, 1605 Organic Chemistry, 2707 Complementary and alternative medicine, 3002 Drug Discovery, 3003 Pharmaceutical Science, 3004 Pharmacology

Relation: orcid:0000-0001-6689-4236; orcid:0000-0003-3147-3460; AF 511105

الاتاحة: https://espace.library.uq.edu.au/view/UQ:226104

المؤلفون: Mark E. Cooper, Soumya Ramu, Tomislav Karoli, Ute Möllmann, Johnny X. Huang, Bernd Becker, Johannes Zuegg

المصدر: Journal of medicinal chemistry. 55(17)

مصطلحات موضوعية: Drug, Low toxicity, biology, Ligand, Chemistry, Stereochemistry, media_common.quotation_subject, In silico, Antitubercular Agents, Thiazines, biology.organism_classification, Ligands, Mycobacterium tuberculosis, Drug Design, Drug Discovery, Molecular Medicine, Cytotoxicity, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad0603e26c67dbf8a89a9949ec501e6
https://pubmed.ncbi.nlm.nih.gov/22916795