المؤلفون: Dominique Lambin, Katja Conrath, Tom De Munck, Ann De Blieck, Hans Kelgtermans, Steven Emiel Van Der Plas, Marlon D. Cowart, Christel Jeanne Marie Menet, Sebastien Dropsit, Caroline Joannesse, Oscar Mammoliti, Sebastien Laurent Xavier Martina, Maarten Gees, Giovanni Tricarico, Martin James Inglis Andrews, Anne-Sophie Wesse

المصدر: Journal of Medicinal Chemistry. 64:343-353

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Cystic Fibrosis, Pyridines, Cystic Fibrosis Transmembrane Conductance Regulator, Gating, Computational biology, 01 natural sciences, Cystic fibrosis, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Humans, 030304 developmental biology, 0303 health sciences, biology, Drug discovery, Lumacaftor, Potentiator, medicine.disease, Small molecule, Cystic fibrosis transmembrane conductance regulator, Rats, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, biology.protein, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c3164798d3ba2edd8da65585ae94bc
https://doi.org/10.1021/acs.jmedchem.0c01796

المؤلفون: Sebastien Dropsit, Pieter F. W. Stouten, Linda Tomaskovic, Thierry Christophe, Ellen van der Aar, Maarten Gees, Luc Nelles, Mia Jans, Monica Borgonovi, Evelyne M. Quinton, Katja Conrath, Jan Van Der Schueren, Caroline Joannesse, Hans Kelgtermans, Martin James Inglis Andrews, Sebastien Laurent Xavier Martina, Oscar Mammoliti, Ann De Blieck, Steven Emiel Van Der Plas, Tom De Munck

المصدر: Journal of Medicinal Chemistry. 61:1425-1435

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Mutant, Pharmacology, medicine.disease_cause, Cystic fibrosis, Ivacaftor, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Structure–activity relationship, Mutation, biology, Chemistry, Drug discovery, respiratory system, Potentiator, medicine.disease, digestive system diseases, Cystic fibrosis transmembrane conductance regulator, respiratory tract diseases, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dc1598dc3e22fb401aa0908c21814b75
https://doi.org/10.1021/acs.jmedchem.7b01288

المؤلفون: Steven Emiel Van Der Plas, Ann De Blieck, Dominique Lambin, Giovanni Tricarico, Martin James Inglis Andrews, Anne-Sophie Wesse, Marlon D. Cowart, Katja Conrath, Tom De Munck, Maarten Gees, Christel Jeanne Marie Menet, Hans Kelgtermans, Oscar Mammoliti, Caroline Joannesse, Sebastien Laurent Xavier Martina, Sebastien Dropsit

المصدر: Journal of Medicinal Chemistry. 64:13933-13933

مصطلحات موضوعية: Chemistry, Drug Discovery, MEDLINE, medicine, Molecular Medicine, Potentiator, Once daily, medicine.disease, Bioinformatics, Cystic fibrosis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ef530fe540a7f240ca9942862582716b
https://doi.org/10.1021/acs.jmedchem.1c01537

المؤلفون: Steven E, Van der Plas, Hans, Kelgtermans, Tom, De Munck, Sébastien L X, Martina, Sébastien, Dropsit, Evelyne, Quinton, Ann, De Blieck, Caroline, Joannesse, Linda, Tomaskovic, Mia, Jans, Thierry, Christophe, Ellen, van der Aar, Monica, Borgonovi, Luc, Nelles, Maarten, Gees, Pieter, Stouten, Jan, Van Der Schueren, Oscar, Mammoliti, Katja, Conrath, Martin, Andrews

المصدر: Journal of medicinal chemistry. 61(4)

مصطلحات موضوعية: Structure-Activity Relationship, Cystic Fibrosis, Drug Discovery, Mutation, Animals, Cystic Fibrosis Transmembrane Conductance Regulator, Humans, Pyrazoles, Mutant Proteins, Quinolones, Aminophenols, Chloride Channel Agonists, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::528097bcdc809fb179a6c30494225cb7
https://pubmed.ncbi.nlm.nih.gov/29148763