المؤلفون: Goltermann, Lise, Shahryari, Shahab, Rybtke, Morten, Tolker-Nielsen, Tim

المصدر: Goltermann , L , Shahryari , S , Rybtke , M & Tolker-Nielsen , T 2024 , ' Microbial Primer : The catalytic biofilm matrix ' , Microbiology (United Kingdom) , vol. 170 , no. 8 , 001497 . https://doi.org/10.1099/mic.0.001497

مصطلحات موضوعية: biofilm, catalytic functions, environment, extracellular polymeric substances, infections, matrix

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/microbial-primer(d0536373-a422-46e9-b14a-5672a7b63094).html
https://doi.org/10.1099/mic.0.001497
https://curis.ku.dk/ws/files/408329050/Microbial_Primer.pdf

المؤلفون: Andersen, Jens Bo, Rybtke, Morten, Tolker-Nielsen, Tim

المصدر: Andersen , J B , Rybtke , M & Tolker-Nielsen , T 2024 , ' The dynamics of biofilm development and dispersal should be taken into account when quantifying biofilm via the crystal violet microtiter plate assay ' , Biofilm , vol. 8 , 100207 . https://doi.org/10.1016/j.bioflm.2024.100207

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/the-dynamics-of-biofilm-development-and-dispersal-should-be-taken-into-account-when-quantifying-biofilm-via-the-crystal-violet-microtiter-plate-assay(ce476974-0fd8-4508-a542-4b68c6192c4d).html
https://doi.org/10.1016/j.bioflm.2024.100207
https://curis.ku.dk/ws/files/412528038/1_s2.0_S2590207524000327_main.pdf

المؤلفون: Blanco Romero, Esther, Garrido-Sanz, Daniel, Durán Wendt, David Ricardo, Rybtke, Morten, Tolker-Nielsen, Tim, Redondo Nieto, Miguel, Rivilla Palma, Rafael, Martín Basanta, Marta

المساهمون: UAM. Departamento de Biología

مصطلحات موضوعية: Biofilm, dynamic biofilm formation, extracellular matrix components, flow cell, motility, pseudomonas ogarae F113, rhizosphere, surface attachment, Biología y Biomedicina / Biología

وصف الملف: application/pdf

Relation: Frontiers in Microbiology; https://doi.org/10.3389/fmicb.2024.1341728; Gobierno de España. PID2021-125070OB-I00; https://www.frontiersin.org/articles/10.3389/fmicb.2024.1341728/full#supplementary-material; Frontiers in Microbiology 15 (2024): 1341728; http://hdl.handle.net/10486/716451

الاتاحة: http://hdl.handle.net/10486/716451
https://doi.org/10.3389/fmicb.2024.1341728

المؤلفون: Kristensen, Rasmus, Andersen, Jens Bo, Rybtke, Morten, Jansen, Charlotte Uldahl, Fritz, Blaine Gabriel, Kiilerich, Rikke Overgaard, Uhd, Jesper, Bjarnsholt, Thomas, Qvortrup, Katrine, Tolker-Nielsen, Tim, Givskov, Michael, Jakobsen, Tim Holm

المصدر: Kristensen , R , Andersen , J B , Rybtke , M , Jansen , C U , Fritz , B G , Kiilerich , R O , Uhd , J , Bjarnsholt , T , Qvortrup , K , Tolker-Nielsen , T , Givskov , M & Jakobsen , T H 2024 , ' Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump ' , Antimicrobial Agents and Chemotherapy , vol. 68 , no. 2 , e0138723 . https://doi.org/10.1128/aac.01387-23

مصطلحات موضوعية: MexEF-oprN, Pseudomonas aeruginosa, Quorum sensing, Quorum-sensing inhibitor, Thiol-reactive compound, Virulence factors

وصف الملف: application/pdf

Relation: https://orbit.dtu.dk/en/publications/9a8c52e2-5760-4626-92de-e9a09fade2c3

الاتاحة: https://orbit.dtu.dk/en/publications/9a8c52e2-5760-4626-92de-e9a09fade2c3
https://doi.org/10.1128/aac.01387-23
https://backend.orbit.dtu.dk/ws/files/351458948/kristensen-et-al-2024-inhibition-of-pseudomonas-aeruginosa-quorum-sensing-by-chemical-induction-of-the-mexef-oprn.pdf

المؤلفون: Jansen, Charlotte Uldahl, Grier, Katja Egeskov, Andersen, Jens Bo, Hultqvist, Louise Dahl, Nilsson, Martin, Moser, Claus, Graz, Michael, Tolker-Nielsen, Tim, Givskov, Michael, Qvortrup, Katrine

المصدر: Jansen , C U , Grier , K E , Andersen , J B , Hultqvist , L D , Nilsson , M , Moser , C , Graz , M , Tolker-Nielsen , T , Givskov , M & Qvortrup , K 2024 , ' Upscaling and Risk Evaluation of the Synthesis of the 3,5-Diamino-1H-Pyrazole, Disperazol ' , International Journal of Molecular Sciences , vol. 25 , no. 12 , 6737 . https://doi.org/10.3390/ijms25126737

مصطلحات موضوعية: biofilm, c-di-GMP, dispersal, dust analysis, flow chemistry, large-scale synthesis, preclinical, Pseudomonas aeruginosa, pyrazole, safety

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/upscaling-and-risk-evaluation-of-the-synthesis-of-the-35diamino1hpyrazole-disperazol(86340c84-9889-4fea-ad32-0dea2af0d342).html
https://doi.org/10.3390/ijms25126737
https://curis.ku.dk/ws/files/398072081/ijms_25_06737.pdf

المؤلفون: Hultqvist, Louise Dahl, Andersen, Jens Bo, Nilsson, Carl Martin, Jansen, Charlotte Uldahl, Rybtke, Morten, Jakobsen, Tim Holm, Nielsen, Thomas Eiland, Qvortrup, Klaus, Moser, Claus, Graz, Michael, Qvortrup, Katrine, Tolker-Nielsen, Tim, Givskov, Michael

المصدر: Hultqvist , L D , Andersen , J B , Nilsson , C M , Jansen , C U , Rybtke , M , Jakobsen , T H , Nielsen , T E , Qvortrup , K , Moser , C , Graz , M , Qvortrup , K , Tolker-Nielsen , T & Givskov , M 2024 , ' High efficacytreatment of murine Pseudomonas aeruginosa catheter-associated urinary tract infections using the c-di-GMP modulating anti-biofilmcompound Disperazol in combination with ciprofloxacin ' , Antimicrobial Agents and Chemotherapy , vol. 68 , no. 6 , e01481-23 . https://doi.org/10.1128/aac.01481-23

مصطلحات موضوعية: anti-biofilmcompound, antibiotic resistance (AMR), biofilm,infection, c-di-GMP regulation, CAUTI, Pseudomonas aeruginosa

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/high-efficacytreatment-of-murine-pseudomonas-aeruginosa-catheterassociated-urinary-tract-infections-using-the-cdigmp-modulating-antibiofilmcompound-disperazol-in-combination-with-ciprofloxacin(8624cb77-4256-4682-aff1-368da07fbbcb).html
https://doi.org/10.1128/aac.01481-23
https://curis.ku.dk/ws/files/394982409/High_efficacy_treatment.pdf

المؤلفون: Røder, Henriette Lyng, Cristidi, Eleni, Amador, Cristina, Trivedi, Urvish, Russel, Jakob, Kragh, Kasper N., Tolker‐Nielsen, Tim, Bjarnsholt, Thomas, Music, Samra, Olesen, Asmus K., Svensson, Birte, Madsen, Jonas S., Herschend, Jakob, Kreft, Jan‐Ulrich, Burmølle, Mette

المصدر: Røder , H L , Cristidi , E , Amador , C , Trivedi , U , Russel , J , Kragh , K N , Tolker‐Nielsen , T , Bjarnsholt , T , Music , S , Olesen , A K , Svensson , B , Madsen , J S , Herschend , J , Kreft , JU & Burmølle , M 2023 , ' Impact of Biofilm Structure and Phenotypes on Plasmid Transfer and Stability ' , 16th Symposium on Bacterial Genetics and Ecology , Copenhagen , Denmark , 26/06/2023 - 30/06/2023 pp. 204-204 .

وصف الملف: application/pdf

الاتاحة: https://orbit.dtu.dk/en/publications/502d76e4-a544-491c-9845-e5aa431678da
https://backend.orbit.dtu.dk/ws/files/331166800/Pages_from_CAP_Partner_Bageco2023_programme_A5_abstract_korr10_16.pdf

المؤلفون: Kragh, Kasper N., Tolker-Nielsen, Tim, Lichtenberg, Mads

المصدر: Kragh , K N , Tolker-Nielsen , T & Lichtenberg , M 2023 , ' The non-attached biofilm aggregate ' , Communications Biology , vol. 6 , 898 . https://doi.org/10.1038/s42003-023-05281-4

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/the-nonattached-biofilm-aggregate(1640001b-8734-49ca-b14f-cbcef9a18b01).html
https://doi.org/10.1038/s42003-023-05281-4
https://curis.ku.dk/ws/files/368637197/s42003_023_05281_4.pdf

المؤلفون: Liang, Ziwei, Nilsson, Martin, Kragh, Kasper Nørskov, Hedal, Ida, Alcàcer-Almansa, Júlia, Kiilerich, Rikke Overgaard, Andersen, Jens Bo, Tolker-Nielsen, Tim

المصدر: Liang , Z , Nilsson , M , Kragh , K N , Hedal , I , Alcàcer-Almansa , J , Kiilerich , R O , Andersen , J B & Tolker-Nielsen , T 2023 , ' The role of individual exopolysaccharides in antibiotic tolerance of Pseudomonas aeruginosa aggregates ' , Frontiers in Microbiology , vol. 14 , 1187708 . https://doi.org/10.3389/fmicb.2023.1187708

مصطلحات موضوعية: aggregates, antibiotic tolerance, biofilm, extracellular matrix, Pseudomonas aeruginosa

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/the-role-of-individual-exopolysaccharides-in-antibiotic-tolerance-of-pseudomonas-aeruginosa-aggregates(85241993-0687-486f-bb80-301a77ddeb8f).html
https://doi.org/10.3389/fmicb.2023.1187708
https://curis.ku.dk/ws/files/358560528/fmicb_14_1187708.pdf

المؤلفون: Beilharz, Katrin, Kragh, Kasper Nørskov, Fritz, Blaine, Kirkegaard, Julius B., Tolker-Nielsen, Tim, Bjarnsholt, Thomas, Lichtenberg, Mads

المصدر: Beilharz , K , Kragh , K N , Fritz , B , Kirkegaard , J B , Tolker-Nielsen , T , Bjarnsholt , T & Lichtenberg , M 2023 , ' Protocol to assess metabolic activity of Pseudomonas aeruginosa by measuring heat flow using isothermal calorimetry ' , STAR Protocols , vol. 4 , no. 2 , 102269 . https://doi.org/10.1016/j.xpro.2023.102269

مصطلحات موضوعية: Cell-based Assays, Metabolism, Microbiology

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/protocol-to-assess-metabolic-activity-of-pseudomonas-aeruginosa-by-measuring-heat-flow-using-isothermal-calorimetry(bb683884-c902-488f-8d33-4e7681f82049).html
https://doi.org/10.1016/j.xpro.2023.102269
https://curis.ku.dk/ws/files/346248558/1_s2.0_S2666166723002277_main.pdf

المؤلفون: Armengol, Eva, Kragh, Kasper Nørskov, Tolker-Nielsen, Tim, Sierra, Josep M., Higazy, Doaa, Ciofu, Oana, Viñas, Miguel, Høiby, Niels

المصدر: Armengol , E , Kragh , K N , Tolker-Nielsen , T , Sierra , J M , Higazy , D , Ciofu , O , Viñas , M & Høiby , N 2023 , ' Colistin Enhances Rifampicin's Antimicrobial Action in Colistin-Resistant Pseudomonas aeruginosa Biofilms ' , Antimicrobial Agents and Chemotherapy , vol. 67 , no. 4 , e0164122 . https://doi.org/10.1128/aac.01641-22

مصطلحات موضوعية: biofilm, colistin, dynamic, rifampicin, synergism

الاتاحة: https://researchprofiles.ku.dk/da/publications/colistin-enhances-rifampicins-antimicrobial-action-in-colistinresistant-pseudomonas-aeruginosa-biofilms(726fc19d-9fb0-45de-88c3-eb75bda4fdc4).html
https://doi.org/10.1128/aac.01641-22
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112245/pdf/aac.01641-22.pdf

المؤلفون: Gür, Melisa, Erdmann, Jelena, Will, Anke, Liang, Ziwei, Andersen, Jens Bo, Tolker-Nielsen, Tim, Häussler, Susanne

المساهمون: Deutsche Forschungsgemeinschaft, European Union, Novo Nordisk Foundation, Cystic Fibrosis Trust

المصدر: FEMS Microbes ; volume 4 ; ISSN 2633-6685

الاتاحة: http://dx.doi.org/10.1093/femsmc/xtad012
https://academic.oup.com/femsmicrobes/advance-article-pdf/doi/10.1093/femsmc/xtad012/50908825/xtad012.pdf
https://academic.oup.com/femsmicrobes/article-pdf/doi/10.1093/femsmc/xtad012/51307294/xtad012.pdf

المؤلفون: Bellich, Barbara, Terán, Lucrecia C., Fazli, Magnus M., Berti, Francesco, Rizzo, Roberto, Tolker-Nielsen, Tim, Cescutti, Paola

المساهمون: Cornell University

المصدر: Carbohydrate Polymers ; volume 301, page 120318 ; ISSN 0144-8617

الاتاحة: http://dx.doi.org/10.1016/j.carbpol.2022.120318
https://api.elsevier.com/content/article/PII:S0144861722012231?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0144861722012231?httpAccept=text/plain

المؤلفون: Blanco-Romero, Esther, Garrido-Sanz, Daniel, Durán, David, Rybtke, Morten, Tolker-Nielsen, Tim, Redondo-Nieto, Miguel, Rivilla, Rafael, Martín, Marta

المصدر: Blanco-Romero , E , Garrido-Sanz , D , Durán , D , Rybtke , M , Tolker-Nielsen , T , Redondo-Nieto , M , Rivilla , R & Martín , M 2024 , ' Role of extracellular matrix components in biofilm formation and adaptation of Pseudomonas ogarae F113 to the rhizosphere environment ' , Frontiers in Microbiology , vol. 15 , 1341728 .

مصطلحات الفهرس: biofilm, dynamic biofilm formation, extracellular matrix components, flow cell, motility, Pseudomonas ogarae F113, rhizosphere, surface attachment, article

URL: https://curis.ku.dk/portal/da/publications/role-of-extracellular-matrix-components-in-biofilm-formation-and-adaptation-of-pseudomonas-ogarae-f113-to-the-rhizosphere-environment(224e643f-ca95-4d64-b032-fba62f3dc158).html
https://doi.org/10.3389/fmicb.2024.1341728
https://curis.ku.dk/ws/files/382901514/Role_of_extracellular_matrix.pdf

المؤلفون: Steiner, Elisabeth, Shilling, Rebecca E, Richter, Anja M, Schmid, Nadine, Fazli, Mustafa, Kaever, Volkhard, Jenal, Urs, Tolker-Nielsen, Tim, Eberl, Leo

المصدر: Steiner, Elisabeth; Shilling, Rebecca E; Richter, Anja M; Schmid, Nadine; Fazli, Mustafa; Kaever, Volkhard; Jenal, Urs; Tolker-Nielsen, Tim; Eberl, Leo (2022). The BDSF quorum sensing receptor RpfR regulates Bep exopolysaccharide synthesis in Burkholderia cenocepacia via interaction with the transcriptional regulator BerB. npj Biofilms and Microbiomes, 8:93.

مصطلحات موضوعية: Department of Plant and Microbial Biology, Zurich-Basel Plant Science Center, 580 Plants (Botany), Applied Microbiology and Biotechnology, Microbiology, Biotechnology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/224012/1/41522_2022_Article_356.pdf; info:pmid/36418316; urn:issn:2055-5008

الاتاحة: https://www.zora.uzh.ch/id/eprint/224012/
https://www.zora.uzh.ch/id/eprint/224012/1/41522_2022_Article_356.pdf

المؤلفون: Wu, Hong, Song, Lulu, Yam, Joey Kuok Hoong, Plotkin, Marian, Wang, Hengzhuang, Rybtke, Morten, Seliktar, Dror, Kofidis, Theodoros, Høiby, Niels, Tolker-Nielsen, Tim, Song, Zhijun, Givskov, Michael

المصدر: Wu , H , Song , L , Yam , J K H , Plotkin , M , Wang , H , Rybtke , M , Seliktar , D , Kofidis , T , Høiby , N , Tolker-Nielsen , T , Song , Z & Givskov , M 2022 , ' Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm : Insights from the application of a novel PF hydrogel model in vitro and in vivo ' , Frontiers in Cellular and Infection Microbiology , vol. 12 , 826450 . https://doi.org/10.3389/fcimb.2022.826450

مصطلحات موضوعية: antibiotic resistance, biofilm infection, in vivo model, PF hydrogel, Pseudomonas aeruginosa

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/4fdd6908-12df-4730-b1c7-7300794f830a

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/4fdd6908-12df-4730-b1c7-7300794f830a
https://doi.org/10.3389/fcimb.2022.826450
https://findresearcher.sdu.dk/ws/files/205443135/Open_Access_Version.pdf

المؤلفون: Flagstad, Thomas, Pedersen, Mette T., Jakobsen, Tim H., Felding, Jakob, Tolker-Nielsen, Tim, Givskov, Michael, Qvortrup, Katrine, Nielsen, Thomas E.

المساهمون: Singapore Centre for Environmental Life Sciences and Engineering

مصطلحات موضوعية: Science::Biological sciences, Antibiotics, Bacterial Topoisomerase Inhibitors

وصف الملف: application/pdf

Relation: Bioorganic & Medicinal Chemistry Letters; Flagstad, T., Pedersen, M. T., Jakobsen, T. H., Felding, J., Tolker-Nielsen, T., Givskov, M., Qvortrup, K. & Nielsen, T. E. (2022). Solid-phase synthesis and biological evaluation of piperazine-based novel bacterial topoisomerase inhibitors. Bioorganic & Medicinal Chemistry Letters, 57, 128499-. https://dx.doi.org/10.1016/j.bmcl.2021.128499; https://hdl.handle.net/10356/163859; 2-s2.0-85121513097; 57; 128499

الاتاحة: https://hdl.handle.net/10356/163859
https://doi.org/10.1016/j.bmcl.2021.128499

المؤلفون: Yam, Joey Kuok Hoong, Aung, Thet Tun, Chua, Song Lin, Cheng, Yingying, Kohli, Gurjeet Singh, Zhou, Jianuan, Constancias, Florentin, id_orcid:0 000-0002-8612-384X, Liu, Yang, Cai, Zhao, Salido, May Margarette Santillan, Drautz-Moses, Daniela I., Rice, Scott A., Schuster, Stephan C., Boo, Zhao Zhi, Wu, Bin, Kjelleberg, Staffan, Tolker-Nielsen, Tim, Lakshminarayanan, Rajamani, Beuerman, Roger W., Yang, Liang, Givskov, Michael

المصدر: Infection and immunity, 90 (8)

مصطلحات موضوعية: Pseudomonas aeruginosa, in vivo biofilms, mouse corneal infection, transcriptomics, c-di-GMP, type III secretion system, immune response

وصف الملف: application/application/pdf

Relation: info:eu-repo/semantics/altIdentifier/wos/000835273900002; http://hdl.handle.net/20.500.11850/563559

الاتاحة: https://hdl.handle.net/20.500.11850/563559
https://doi.org/10.3929/ethz-b-000563559

المؤلفون: Lichtenberg, Mads, Kragh, Kasper Nørskov, Fritz, Blaine, Kirkegaard, Julius B., Tolker-Nielsen, Tim, Bjarnsholt, Thomas

المصدر: Lichtenberg , M , Kragh , K N , Fritz , B , Kirkegaard , J B , Tolker-Nielsen , T & Bjarnsholt , T 2022 , ' Cyclic-di-GMP signaling controls metabolic activity in Pseudomonas aeruginosa ' , Cell Reports , vol. 41 , no. 3 , pp. 111515 . https://doi.org/10.1016/j.celrep.2022.111515

مصطلحات موضوعية: biofilm, c-di-GMP, CP: Microbiology, exopolysaccharides, matrix, metabolism, microcalorimetry, Pseudomonas aeruginosa

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/cyclicdigmp-signaling-controls-metabolic-activity-in-pseudomonas-aeruginosa(031a7b01-cf07-4da7-a5ae-98065b8e1bf9).html
https://doi.org/10.1016/j.celrep.2022.111515
https://curis.ku.dk/ws/files/324317740/1_s2.0_S2211124722013651_main.pdf

المؤلفون: Liang, Ziwei, Rybtke, Morten, Kragh, Kasper Nørskov, Johnson, Owen, Schicketanz, Muriel, Zhang, Yong Everett, Andersen, Jens Bo, Tolker-Nielsen, Tim

المصدر: Liang , Z , Rybtke , M , Kragh , K N , Johnson , O , Schicketanz , M , Zhang , Y E , Andersen , J B & Tolker-Nielsen , T 2022 , ' Transcription of the Alginate Operon in Pseudomonas aeruginosa Is Regulated by c-di-GMP ' , Microbiology Spectrum , vol. 10 , no. 4 , e00675-22 . https://doi.org/10.1128/spectrum.00675-22

مصطلحات موضوعية: c-di-GMP, alginate, aeruginosa, transcriptional regulators, BINDING PROTEIN, BIOFILM FORMATION, ALGD PROMOTER, GENE, EXOPOLYSACCHARIDE, DNA, RECEPTOR, DOMAIN, IDENTIFICATION, SYSTEM

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/transcription-of-the-alginate-operon-in-pseudomonas-aeruginosa-is-regulated-by-cdigmp(264e999d-1b98-4072-b094-c8c891921392).html
https://doi.org/10.1128/spectrum.00675-22
https://curis.ku.dk/ws/files/320496580/spectrum.00675_22.pdf