المؤلفون: Psaras, Yiangos, Margara, Francesca, Cicconet, Marcelo, Sparrow, Alexander J, Repetti, Giuliana G, Schmid, Manuel, Steeples, Violetta, Wilcox, Jonathan AL, Bueno-Orovio, Alfonso, Redwood, Charles S, Watkins, Hugh C, Robinson, Paul, Rodriguez, Blanca, Seidman, Jonathan G, Seidman, Christine E, Toepfer, Christopher N

المصدر: Circulation research. 129(2)

مصطلحات موضوعية: Cells, Cultured, Myocytes, Cardiac, Animals, Humans, Guinea Pigs, Calcium, Troponin I, Microscopy, Fluorescence, Calcium Signaling, Kinetics, Mutation, Missense, Algorithms, Image Processing, Computer-Assisted, Induced Pluripotent Stem Cells, High-Throughput Screening Assays, Workflow, Automation, Laboratory, calcium, cardiomyopathy, hypertrophic, induced pluripotent stem cells, myocytes, cardiac, photobleaching, cardiomyopathy, hypertrophic, myocytes, cardiac, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Cardiovascular System & Hematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3352c1zp
https://escholarship.org/content/qt3352c1zp/qt3352c1zp.pdf

المؤلفون: Zhang, Yujia, Tan, Cheryl M. J., Toepfer, Christopher N., Lu, Xin, Bayley, Hagan

Relation: https://doi.org/10.5281/zenodo.13378257; https://doi.org/10.5281/zenodo.13378258; oai:zenodo.org:13378258

الاتاحة: https://doi.org/10.5281/zenodo.13378258

المؤلفون: Sharma, Arun, Wasson, Lauren K, Willcox, Jon Al, Morton, Sarah U, Gorham, Joshua M, DeLaughter, Daniel M, Neyazi, Meraj, Schmid, Manuel, Agarwal, Radhika, Jang, Min Young, Toepfer, Christopher N, Ward, Tarsha, Kim, Yuri, Pereira, Alexandre C, DePalma, Steven R, Tai, Angela, Kim, Seongwon, Conner, David, Bernstein, Daniel, Gelb, Bruce D, Chung, Wendy K, Goldmuntz, Elizabeth, Porter, George, Tristani-Firouzi, Martin, Srivastava, Deepak, Seidman, Jonathan G, Seidman, Christine E, Pediatric Cardiac Genomics Consortium

مصطلحات موضوعية: Pediatric Cardiac Genomics Consortium, CRISPR, development, developmental biology, gene mutation, heart, human, iPSC, regenerative medicine, stem cells, Biochemistry and Cell Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/49c8p24m

المؤلفون: Pua, Chee Jian, Tham, Nevin, Chin, Calvin WL, Walsh, Roddy, Khor, Chiea Chuen, Toepfer, Christopher N, Repetti, Giuliana G, Garfinkel, Amanda C, Ewoldt, Jourdan F, Cloonan, Paige, Chen, Christopher S, Lim, Shi Qi, Cai, Jiashen, Loo, Li Yang, Kong, Siew Ching, Chiang, Charleston WK, Whiffin, Nicola, de Marvao, Antonio, Lio, Pei Min, Hii, An An, Yang, Cheng Xi, Le, Thu Thao, Bylstra, Yasmin, Lim, Weng Khong, Teo, Jing Xian, Padilha, Kallyandra, Silva, Gabriela V, Pan, Bangfen, Govind, Risha, Buchan, Rachel J, Barton, Paul JR, Tan, Patrick, Foo, Roger, Yip, James WL, Wong, Raymond CC, Chan, Wan Xian, Pereira, Alexandre C, Tang, Hak Chiaw, Jamuar, Saumya Shekhar, Ware, James S, Seidman, Jonathan G, Seidman, Christine E, Cook, Stuart A

المصدر: Circulation Genomic and Precision Medicine. 13(5)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Genetics, Cardiovascular, Clinical Research, Heart Disease, 2.1 Biological and endogenous factors, Aetiology, Asian People, Cardiomyopathy, Hypertrophic, China, Female, Gene Frequency, Genetic Association Studies, Haplotypes, Heart Ventricles, Heterozygote, Humans, Male, Middle Aged, Odds Ratio, Polymorphism, Single Nucleotide, Risk, Singapore, Troponin I, Troponin T, cardiomyopathies, hypertrophy, population, troponin I, troponin T, Medical Biotechnology, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/78x4h35w
https://escholarship.org/content/qt78x4h35w/qt78x4h35w.pdf

المؤلفون: Robinson, Paul, Sparrow, Alexander J., Psaras, Yiangos, Steeples, Violetta, Simon, Jillian, Broyles, Connor N., Chang, Yu-Fen, Brook, Frances A., Wang, Ying-Jie, Blease, Andrew, Zhang, Xiaoyu, Abassi, Yama A., Geeves, Michael A., Toepfer, Christopher N., Watkins, Hugh, Redwood, Charles, Daniels, Matthew J.

مصطلحات موضوعية: Q Science (General)

وصف الملف: application/pdf

Relation: https://kar.kent.ac.uk/101223/27/Comparing%20the%20effects_Geeves_published.pdf; https://kar.kent.ac.uk/101223/1/Comparing%20the%20effects%20of%20chemical_Geeves.pdf; Robinson, Paul, Sparrow, Alexander J., Psaras, Yiangos, Steeples, Violetta, Simon, Jillian, Broyles, Connor N., Chang, Yu-Fen, Brook, Frances A., Wang, Ying-Jie, Blease, Andrew, and others. Zhang, Xiaoyu, Abassi, Yama A., Geeves, Michael A., Toepfer, Christopher N., Watkins, Hugh, Redwood, Charles, and Daniels, Matthew J. (hide) (2023) Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes. Journal of Molecular and Cellular Cardiology, 180 . pp. 44-57. ISSN 0022-2828. E-ISSN 1095-8584. (doi:10.1016/j.yjmcc.2023.04.008 ) (KAR id:101223 )

الاتاحة: https://kar.kent.ac.uk/101223/
https://kar.kent.ac.uk/101223/27/Comparing%20the%20effects_Geeves_published.pdf
https://kar.kent.ac.uk/101223/1/Comparing%20the%20effects%20of%20chemical_Geeves.pdf
https://doi.org/10.1016/j.yjmcc.2023.04.008

المؤلفون: Psaras, Yiangos, Toepfer, Christopher N.

المصدر: Experimental Physiology ; volume 109, issue 2, page 175-189 ; ISSN 0958-0670 1469-445X

الاتاحة: http://dx.doi.org/10.1113/ep090436
https://physoc.onlinelibrary.wiley.com/doi/pdf/10.1113/EP090436

المؤلفون: Venturini, Gabriela, Alvim, Juliana M., Padilha, Kallyandra, Toepfer, Christopher N., Gorham, Joshua M., Wasson, Lauren K., Biagi, Diogo, Schenkman, Sergio, Carvalho, Valdemir M., Salgueiro, Jessica S., Cardozo, Karina H. M., Krieger, Jose E., Pereira, Alexandre C., Seidman, Jonathan G., Seidman, Christine E.

المساهمون: National Institutes of Health, Fundação de Amparo à Pesquisa do Estado de São Paulo

المصدر: Frontiers in Cellular and Infection Microbiology ; volume 13 ; ISSN 2235-2988

الاتاحة: http://dx.doi.org/10.3389/fcimb.2023.1098457
https://www.frontiersin.org/articles/10.3389/fcimb.2023.1098457/full

المؤلفون: Yujia Zhang, Tan, Cheryl M. J., Toepfer, Christopher N., Xin Lu, Bayley, Hagan

المصدر: Science; 11/29/2024, Vol. 386 Issue 6725, p1024-1030, 7p, 5 Diagrams

المؤلفون: Meier, Anna B., Raj Murthi, Sarala, Rawat, Hilansi, Toepfer, Christopher N., Santamaria, Gianluca, Schmid, Manuel, Mastantuono, Elisa, Schwarzmayr, Thomas, Berutti, Riccardo, Cleuziou, Julie, Ewert, Peter, Görlach, Agnes, Klingel, Karin, Laugwitz, Karl-Ludwig, Seidman, Christine E., Seidman, Jonathan G., Moretti, Alessandra, Wolf, Cordula M.

مصطلحات موضوعية: info:eu-repo/classification/ddc

وصف الملف: application/pdf

Relation: https://mediatum.ub.tum.de/1755524; https://mediatum.ub.tum.de/doc/1755524/document.pdf

الاتاحة: https://mediatum.ub.tum.de/1755524
https://mediatum.ub.tum.de/doc/1755524/document.pdf
https://doi.org/10.1016/j.isci.2021.103596

المؤلفون: Toepfer, Christopher N., Padrón, Raúl, Seidman, Christine E.

المساهمون: Division of Cell Biology and Imaging, Department of Radiology

المصدر: Circulation ; 141 ; 10 ; 828-842

مصطلحات موضوعية: cardiomyopathy, hypertrophic, cardiovascular physiological phenomena, myosins, sarcomeres, Amino Acids, Peptides, and Proteins, Cardiovascular Diseases, Cell Biology, Cellular and Molecular Physiology, Enzymes and Coenzymes

Relation: Link to Article in PubMed; Toepfer CN, Garfinkel AC, Venturini G, Wakimoto H, Repetti G, Alamo L, Sharma A, Agarwal R, Ewoldt JF, Cloonan P, Letendre J, Lun M, Olivotto I, Colan S, Ashley E, Jacoby D, Michels M, Redwood CS, Watkins HC, Day SM, Staples JF, Padrón R, Chopra A, Ho CY, Chen CS, Pereira AC, Seidman JG, Seidman CE. Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy. Circulation. 2020 Mar 10;141(10):828-842. doi:10.1161/CIRCULATIONAHA.119.042339. Epub 2020 Jan 27. Erratum in: Circulation. 2020 Mar 10;141(10):e645. PMID: 31983222; PMCID: PMC7077965. Link to article on publisher's site; 0009-7322 (Linking); http://hdl.handle.net/20.500.14038/41401; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5200&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/4181; oapubs/4181

الاتاحة: https://doi.org/10.1161/CIRCULATIONAHA.119.042339
https://hdl.handle.net/20.500.14038/41401
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5200&context=oapubs&unstamped=1
https://escholarship.umassmed.edu/oapubs/4181

المؤلفون: Margara, Francesca, Psaras, Yiangos, Wang, Zhinuo Jenny, Schmid, Manuel, Doste, Ruben, Garfinkel, Amanda C., Repetti, Giuliana G., Seidman, Jonathan G., Seidman, Christine E., Rodriguez, Blanca, Toepfer, Christopher N., Bueno-Orovio, Alfonso

المساهمون: Horizon 2020, Engineering and Physical Sciences Research Council, British Heart Foundation, Wellcome Trust, National Institutes of Health, National Centre for the Replacement, Refinement and Reduction of Animals in Research, BHF Centre of Research Excellence, Oxford

المصدر: Scientific Reports ; volume 12, issue 1 ; ISSN 2045-2322

الاتاحة: http://dx.doi.org/10.1038/s41598-022-26889-2
https://www.nature.com/articles/s41598-022-26889-2.pdf
https://www.nature.com/articles/s41598-022-26889-2

المؤلفون: Ewoldt, Jourdan K., Wang, Miranda C., McLellan, Micheal A., Cloonan, Paige E., Chopra, Anant, Gorham, Joshua, Li, Linqing, DeLaughter, Daniel M., Gao, Xining, Lee, Joshua H., Willcox, Jon A. L., Layton, Olivia, Luu, Rebeccah J., Toepfer, Christopher N., Eyckmans, Jeroen, Seidman, Christine E., Seidman, Jonathan G., Chen, Christopher S.

المصدر: Science Advances ; volume 10, issue 42 ; ISSN 2375-2548

الاتاحة: http://dx.doi.org/10.1126/sciadv.adi6927
https://www.science.org/doi/pdf/10.1126/sciadv.adi6927

المؤلفون: Zhang, Kehan, Cloonan, Paige E., Sundaram, Subramanian, Liu, Feng, Das, Shoshana L., Ewoldt, Jourdan K., Bays, Jennifer L., Tomp, Samuel, Toepfer, Christopher N., Marsiglia, Júlia D. C., Gorham, Joshua, Reichart, Daniel, Eyckmans, Jeroen, Seidman, Jonathan G., Seidman, Christine E., Chen, Christopher S.

المصدر: Science Advances ; volume 7, issue 42 ; ISSN 2375-2548

الاتاحة: http://dx.doi.org/10.1126/sciadv.abh3995
https://www.science.org/doi/pdf/10.1126/sciadv.abh3995

المؤلفون: Toepfer, Christopher N., Garfinkel, Amanda C., Venturini, Gabriela, Wakimoto, Hiroko, Repetti, Giuliana, Alamo, Lorenzo, Sharma, Arun, Agarwal, Radhika, Ewoldt, Jourdan K., Cloonan, Paige, Letendre, Justin, Lun, Mingyue, Olivotto, Iacopo, Colan, Steve, Ashley, Euan, Jacoby, Daniel, Michels, Michelle, Redwood, Charles S., Watkins, Hugh C., Day, Sharlene M., Staples, James F., Padrón, Raúl, Chopra, Anant, Ho, Carolyn Y., Chen, Christopher S., Pereira, Alexandre C., Seidman, Jonathan G., Seidman, Christine E.

المصدر: Circulation ; volume 141, issue 10, page 828-842 ; ISSN 0009-7322 1524-4539

الاتاحة: https://doi.org/10.1161/circulationaha.119.042339
https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.119.042339

المؤلفون: Psaras, Yiangos¹ (AUTHOR), Toepfer, Christopher N.¹ (AUTHOR) christopher.toepfer@cardiov.ox.ac.uk

المصدر: Experimental Physiology. Feb2024, Vol. 109 Issue 2, p175-189. 15p.

المؤلفون: Seidman, Christine E, Ware, James S, Ky, Bonnie, Seidman, Jonathan G, Aplenc, Richard, Barton, Paul J R, DePalma, Steven R, Cook, Stuart A, Alonso-Pulpon, Luis, Lyon, Alexander R, Provencio, Mariano, Lara-Pezzi, Enrique, Prasad, Sanjay K, Rosen, Stuart D, O'Regan, Declan P, Baksi, A John, Dominguez, Fernando, Pantazis, Antonis, Manuel Garcia-Pinilla, Jose, Ahmad, Mian, de Marvao, Antonio, Pascual-Figal, Domingo A, Tayal, Upasana, Buchan, Rachel, Ingold, Nathan, Bardaji, Alfredo, Wilk, Alicja, Midwinter, William, Serrano, Isabel, Whiffin, Nicola, Lupon, Josep, Finkelman, Brian, Walsh, Roddy, Bayes-Genis, Antoni, Mazaika, Erica, Nunez, Beatriz, Govind, Risha, Owens, Anjali T, Li, Jian, Arany, Zoltan, Willcox, Jonathan A, Ito, Kaoru, Patel, Parth, Gorham, Joshua, Getz, Kelly, Toepfer, Christopher N, Smith, Amanda M, Wakimoto, Hiroko, Lunde, Ida G, Alejandra Restrepo-Cordoba, Maria, Kim, Yuri, Garcia-Pavia, Pablo

المساهمون: Universitat Rovira i Virgili

المصدر: Circulation ; 10.1161/CIRCULATIONAHA.118.037934 ; Circulation. 140 (1): 31-41

مصطلحات موضوعية: Cardiac & Cardiovascular Systems,Cardiology and Cardiovascular Medicine,Hematology,Peripheral Vascular Disease,Physiology (Medical), Titin, Polymorphisms, Mutations, Medical oncology, Genetics, Familial dilated cardiomyopathy, Echocardiography, Drug therapy, Congestive-heart-failure, Chemotherapy, Cardiotoxicity, Cardiomyopathies, American society, A-band truncation, Saúde coletiva, Physiology (medical), Peripheral vascular disease, Nutrição, Medicina iii, Medicina ii, Medicina i, Interdisciplinar, Hematology, General medicine, Farmacia, Ensino, Engenharias iv, Engenharias ii, Enfermagem

Relation: http://hdl.handle.net/20.500.11797/imarina5761447

الاتاحة: https://hdl.handle.net/20.500.11797/imarina5761447

المؤلفون: Toepfer, Christopher N., Sharma, Arun, Cicconet, Marcelo, Garfinkel, Amanda C., Mücke, Michael, Neyazi, Meraj, Willcox, Jon A.L., Agarwal, Radhika, Schmid, Manuel, Rao, Jyoti, Ewoldt, Jourdan, Pourquié, Olivier, Chopra, Anant, Chen, Christopher S., Seidman, Jonathan G., Seidman, Christine E.

مصطلحات موضوعية: info:eu-repo/classification/ddc

وصف الملف: application/pdf

Relation: https://mediatum.ub.tum.de/1538447; https://mediatum.ub.tum.de/doc/1538447/document.pdf

الاتاحة: https://mediatum.ub.tum.de/1538447
https://mediatum.ub.tum.de/doc/1538447/document.pdf
https://doi.org/10.1161/circresaha.118.314505

المؤلفون: Garcia-Pavia, Pablo, Kim, Yuri, Restrepo-Cordoba, Maria Alejandra, Lunde, Ida G, Wakimoto, Hiroko, Smith, Amanda M, Toepfer, Christopher N, Getz, Kelly, Gorham, Joshua, Patel, Parth, Ito, Kaoru, Willcox, Jonathan A, Arany, Zoltan, Li, Jian, Owens, Anjali T, Govind, Risha, Nuñez, Beatriz, Mazaika, Erica, Bayes-Genis, Antoni, Walsh, Roddy, Finkelman, Brian, Lupon, Josep, Whiffin, Nicola, Serrano, Isabel, Midwinter, William, Wilk, Alicja, Bardaji, Alfredo, Ingold, Nathan, Buchan, Rachel, Tayal, Upasana, Pascual-Figal, Domingo A, de Marvao, Antonio, Ahmad, Mian, Garcia-Pinilla, Jose Manuel, Pantazis, Antonis, Dominguez, Fernando, John Baksi, A, O'Regan, Declan P, Rosen, Stuart D, Prasad, Sanjay K, Lara-Pezzi, Enrique, Provencio, Mariano, Lyon, Alexander R, Alonso-Pulpon, Luis, Cook, Stuart A, DePalma, Steven R, Barton, Paul J R, Aplenc, Richard, Seidman, Jonathan G, Ky, Bonnie, Ware, James S, Seidman, Christine E

المساهمون: Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (España), Wellcome Trust, Medical Research Council (Reino Unido), National Institute for Health Research (Reino Unido), Imperial College London (Reino Unido), Fondation Leducq, British Heart Foundation, National Institutes of Health (Estados Unidos), Howard Hughes Medical Institute, Fundación ProCNIC, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)

مصطلحات موضوعية: Cardiomyopathies, Drug therapy, Genetics, Medical oncology, Titin

Relation: https://doi.org/10.1161/CIRCULATIONAHA.118.037934; info:eu-repo/grantAgreement/ES/SEV-2015-0505; info:eu-repo/grantAgreement/ES/PI15/01551; info:eu-repo/grantAgreement/ES/PI17/01941; info:eu-repo/grantAgreement/ES/CB16/11/00432; info:eu-repo/grantAgreement/ES/SAF2015-71863-REDT; Circulation. 2019; 140(1):31-41; http://hdl.handle.net/10668/13834; http://hdl.handle.net/20.500.12105/7992; Circulation

الاتاحة: http://hdl.handle.net/10668/13834
https://hdl.handle.net/20.500.12105/7992
https://doi.org/10.1161/CIRCULATIONAHA.118.037934

المؤلفون: Repetti, Giuliana G., Toepfer, Christopher N., Seidman, Jonathan G., Seidman, Christine E.

المصدر: Circulation Research ; volume 124, issue 11, page 1536-1550 ; ISSN 0009-7330 1524-4571

الاتاحة: http://dx.doi.org/10.1161/circresaha.119.313569
https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.119.313569

المؤلفون: Guo, Yuxuan, Jardin, Blake D., Zhou, Pingzhu, Sethi, Isha, Akerberg, Brynn N., Toepfer, Christopher N., Ai, Yulan, Li, Yifei, Ma, Qing, Guatimosim, Silvia, Hu, Yongwu, Varuzhanyan, Grigor, VanDusen, Nathan J., Zhang, Donghui, Chan, David C., Yuan, Guo-Cheng, Seidman, Christine E., Seidman, Jonathan G., Pu, William T.

المصدر: Nature Communications, 9, Art. No. 3837, (2018-09-21)

Relation: https://www.ncbi.nlm.nih.gov/pmc/PMC6155060; eprintid:90055

الاتاحة: https://doi.org/10.1038/s41467-018-06347-2
https://www.ncbi.nlm.nih.gov/pmc/PMC6155060