المؤلفون: Larissa Haertle, Umair Munawar, Hipólito N. C. Hernández, Andres Arroyo‐Barea, Tobias Heckel, Isabel Cuenca, Lucia Martin, Carlotta Höschle, Nicole Müller, Cornelia Vogt, Thorsten Bischler, Paula L. delCampo, Seungbin Han, Natalia Buenache, Xiang Zhou, Florian Bassermann, Johannes Waldschmidt, Torsten Steinbrunn, Leo Rasche, Thorsten Stühmer, Joaquin Martinez‐Lopez, K. Martin Kortüm, Santiago Barrio

المصدر: HemaSphere, Vol 8, Iss 7, Pp n/a-n/a (2024)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2572-9241

URL الوصول: https://doaj.org/article/315cbd46c5644a63a5886179cfc26c50

المؤلفون: Murilo Delgobo, Margarete Heinrichs, Nils Hapke, DiyaaElDin Ashour, Marc Appel, Mugdha Srivastava, Tobias Heckel, Ioakim Spyridopoulos, Ulrich Hofmann, Stefan Frantz, Gustavo Campos Ramos

المصدر: Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: CD4+ T-cells, myocardial aging, inflammaging, NSG animals, immunosenescence, lymphocytes, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.584538/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/9846c1b72f414a5fa7d9a79e7f6accfc

المؤلفون: Manaswini Sivaramakrishnan, Kathleen D. McCarthy, Sébastien Campagne, Sylwia Huber, Sonja Meier, Angélique Augustin, Tobias Heckel, Hélène Meistermann, Melanie N. Hug, Pascale Birrer, Ahmed Moursy, Sarah Khawaja, Roland Schmucki, Nikos Berntenis, Nicolas Giroud, Sabrina Golling, Manuel Tzouros, Balazs Banfai, Gonzalo Duran-Pacheco, Jens Lamerz, Ying Hsiu Liu, Thomas Luebbers, Hasane Ratni, Martin Ebeling, Antoine Cléry, Sergey Paushkin, Adrian R. Krainer, Frédéric H.-T. Allain, Friedrich Metzger

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/86ed63c63e664f938352b802e813bfcc

المؤلفون: Eva C. Thoma, Claudia Merkl, Tobias Heckel, Rachel Haab, Frederic Knoflach, Corinne Nowaczyk, Nicholas Flint, Ravi Jagasia, Sannah Jensen Zoffmann, Hoa Hue Truong, Pascal Petitjean, Sebastian Jessberger, Martin Graf, Roberto Iacone

المصدر: Stem Cell Reports, Vol 3, Iss 4, Pp 539-547 (2014)

مصطلحات موضوعية: Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671114002446; https://doaj.org/toc/2213-6711

URL الوصول: https://doaj.org/article/1054ea04b2084c33907b36fc606bc3c8

المؤلفون: Valentin Metzner, Gloria Herzog, Tobias Heckel, Thorsten Bischler, Julia Hasinger, Christoph Otto, Martin Fassnacht, Andreas Geier, Florian Seyfried, Ulrich Dischinger

المصدر: Journal of Clinical Medicine; Volume 11; Issue 3; Pages: 753

مصطلحات موضوعية: liraglutide, GLP-1, peptide tyrosine tyrosine (PYY), peptide tyrosine tyrosine 3-36 (PYY 3-36 ), RYGB, gastric bypass, obesity, NASH, NAFLD

وصف الملف: application/pdf

Relation: Endocrinology & Metabolism; https://dx.doi.org/10.3390/jcm11030753

الاتاحة: https://doi.org/10.3390/jcm11030753

المؤلفون: Ulrich Dischinger, Tobias Heckel, Thorsten Bischler, Julia Hasinger, Malina Königsrainer, Angelika Schmitt-Böhrer, Christoph Otto, Martin Fassnacht, Florian Seyfried, Mohammed Khair Hankir

المصدر: Nutrients; Volume 14; Issue 1; Pages: 116

مصطلحات موضوعية: obesity, Roux-en-Y gastric bypass surgery, liraglutide, PYY3-36, hypothalamic gene expression

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Nutrition and Metabolism; https://dx.doi.org/10.3390/nu14010116

الاتاحة: https://doi.org/10.3390/nu14010116

المؤلفون: Isabelle C. Becker, Zoltan Nagy, Georgi Manukjan, Melanie Haffner-Luntzer, Maximilian Englert, Tobias Heib, Timo Vögtle, Carina Gross, Richa Bharti, Sascha Dietrich, Kristina Mott, Johannes Heck, Sebastian Stegmaier, Anke Baranowsky, Thorsten Schinke, Nicolas Schlegel, Tobias Heckel, David Stegner, Irina Pleines, Anita Ignatius, Harald Schulze, Bernhard Nieswandt

المصدر: Blood Advances. 6:3155-3161

مصطلحات موضوعية: Blood Platelets, Mice, Inbred C57BL, Mice, Nucleotides, Primary Myelofibrosis, Animals, Hematology, Megakaryocytes, Thrombocytopenia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f476c5fa59f76b4935de2d5584cbac8
https://doi.org/10.1182/bloodadvances.2021006151

المؤلفون: Akua A. Karikari, Rhonda L. McFleder, Eliana Ribechini, Robert Blum, Valentin Bruttel, Susanne Knorr, Mona Gehmeyr, Jens Volkmann, Jonathan M. Brotchie, Fadhil Ahsan, Beatrice Haack, Camelia-Maria Monoranu, Ursula Keber, Rima Yeghiazaryan, Axel Pagenstecher, Tobias Heckel, Thorsten Bischler, Jörg Wischhusen, James B. Koprich, Manfred B. Lutz, Chi Wang Ip

المصدر: Brain, Behavior, and Immunity. 101:194-210

مصطلحات موضوعية: Endocrine and Autonomic Systems, Dopamine, Dopaminergic Neurons, T-Lymphocytes, Immunology, Mice, Transgenic, Parkinson Disease, Mice, Inbred C57BL, Substantia Nigra, Disease Models, Animal, Mice, Behavioral Neuroscience, alpha-Synuclein, Animals, RNA, ddc:610

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434c8700d5508e80586e5d65a53b736a
https://doi.org/10.1016/j.bbi.2022.01.007

المؤلفون: Valentin, Metzner, Gloria, Herzog, Tobias, Heckel, Thorsten, Bischler, Julia, Hasinger, Christoph, Otto, Martin, Fassnacht, Andreas, Geier, Florian, Seyfried, Ulrich, Dischinger

المصدر: Journal of clinical medicine. 11(3)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b5cb86dbb0ce3ffe6036763b52c2b814
https://pubmed.ncbi.nlm.nih.gov/35160204

المؤلفون: Joaquin Martinez-Lopez, Susanne Strifler, Larissa Haertle, K. Martin Kortüm, Ralf C. Bargou, Markus Roth, Andoni Garitano-Trojaola, Maximilian Johannes Steinhardt, Umair Munawar, Panagiota Arampatzi, Matteo DaVia, Tobias Heckel, Hermann Einsele, Nicole Müller, Thorsten Stühmer, Cornelia Vogt, Sascha Dietrich, Leo Rasche, Miguel Gallardo, Santiago Barrio

المصدر: Blood. 134:836-840

مصطلحات موضوعية: 0301 basic medicine, Double hit, business.industry, Immunology, Disease progression, Cell, Tumor cells, Cell Biology, Hematology, Newly diagnosed, medicine.disease, Biochemistry, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Cancer research, Medicine, business, Median survival, Survival analysis, Multiple myeloma, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::24bec71ebae128b9b4055bdfa1dd43af
https://doi.org/10.1182/blood.2019000080

المؤلفون: Roland Schmucki, Asha Ivy Jacob, Fethallah Benmansour, Christian Lerner, Andrea Araujo Del Rosario, Tobias Heckel, Andreas Maunz, Clive S. Mason, Luise Wolf, Marco Prunotto, Sannah Jensen Zoffmann, Michael Prummer, Hoa Hue Truong, Mark Burcin, Haiyuan Ding, Rita Blum Marti, Kenneth Bradley, Maarten Vercruysse, Kurt Amrein

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, 9 (1)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Computer science, Chemical structure, Antibiotics, Drug Evaluation, Preclinical, lcsh:Medicine, Machine learning, computer.software_genre, Article, Machine Learning, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, High-Throughput Screening Assays, medicine, Humans, Potency, lcsh:Science, Multidisciplinary, Bacteria, business.industry, Drug discovery, lcsh:R, Chemical space, Anti-Bacterial Agents, 030104 developmental biology, High-content screening, Classical pharmacology, lcsh:Q, Artificial intelligence, business, computer, 030217 neurology & neurosurgery, Primary screening

وصف الملف: application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450b2ede7c204f5f86abe58b35f4cc77
http://link.springer.com/article/10.1038/s41598-019-39387-9

المؤلفون: Thorsten Bischler, Dimitar Evdokimov, Nadine Egenolf, Franziska Karl, Nurcan Üçeyler, Tobias Heckel

المصدر: Pain.

مصطلحات موضوعية: Keratinocytes, Chemokine, Fibromyalgia, Endothelin receptor type A, Small Fiber Neuropathy, Unmyelinated nerve fiber, Proinflammatory cytokine, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, 030202 anesthesiology, medicine, Humans, Nerve Fibers, Unmyelinated, biology, Epidermis (botany), business.industry, Anesthesiology and Pain Medicine, medicine.anatomical_structure, Neurology, biology.protein, Cancer research, Neurology (clinical), Keratinocyte, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffe1b3b66ea99816a392b40fd7fb9da
https://doi.org/10.1097/j.pain.0000000000002249

المؤلفون: Jörg Vogel, Gianluca Prezza, Sascha Dietrich, Tobias Heckel, Alexander J. Westermann, Christina Homberger

المساهمون: HIRI, Helmholtz-Institut für RNA-basierte Infektionsforschung, Josef-Shneider Strasse 2, 97080 Würzburg, Germany.

المصدر: RNA
RNA (New York, N.Y.)
United States

مصطلحات موضوعية: DNA, Complementary, Polyadenylation, Method, Computational biology, Biology, 03 medical and health sciences, Salmonella, Complementary DNA, Gene expression, Bacteroides, CRISPR, Guide RNA, RNA-Seq, Cas9, Molecular Biology, 030304 developmental biology, Gene Library, 0303 health sciences, Bacteria, Sequence Analysis, RNA, Gene Expression Profiling, 030302 biochemistry & molecular biology, RNA, High-Throughput Nucleotide Sequencing, Nucleic Acid Hybridization, DASH, Ribosomal RNA, bacterial RNA-seq, RNA, Bacterial, RNA, Ribosomal, CRISPR-Cas Systems, ribosomal RNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90555a21e6a63d5c06bf576eb505594d
https://pubmed.ncbi.nlm.nih.gov/32345633

المؤلفون: Murilo Delgobo (761841), Margarete Heinrichs (10165595), Nils Hapke (10165598), DiyaaElDin Ashour (10165601), Marc Appel (10165604), Mugdha Srivastava (6724478), Tobias Heckel (3417707), Ioakim Spyridopoulos (126513), Ulrich Hofmann (8720379), Stefan Frantz (464795), Gustavo Campos Ramos (10165607)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, CD4+ T-cells, myocardial aging, inflammaging, NSG animals, immunosenescence, lymphocytes

Relation: https://figshare.com/articles/dataset/DataSheet_1_Terminally_Differentiated_CD4_T_Cells_Promote_Myocardial_Inflammaging_docx/14058611

الاتاحة: https://doi.org/10.3389/fimmu.2021.584538.s001

المؤلفون: Rowena Sison-Young, Min Wei Wong, Chris S. Pridgeon, Michael J. Cross, Christopher E. Goldring, John Greenman, James E. Sidaway, Vitalina Gryshkova, Joseph Leedale, Paul Walker, Tahera Ansari, Emma L. Wilkinson, Laurence Launay, Susan Gibbs, B. Kevin Park, Tobias Heckel, Stefan Przyborski, R. N. Bearon, Constanze Schlott, Minne B. Heringa, Delilah F. G. Hendriks

المصدر: Pridgeon, C S, Schlott, C, Wong, M W, Heringa, M B, Heckel, T, Leedale, J, Launay, L, Gryshkova, V, Przyborski, S, Bearon, R N, Wilkinson, E L, Ansari, T, Greenman, J, Hendriks, D F G, Gibbs, S, Sidaway, J, Sison-Young, R L, Walker, P, Cross, M J, Park, B K & Goldring, C E P 2018, ' Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms ', Archives of Toxicology, vol. 92, no. 2, pp. 557-569 . https://doi.org/10.1007/s00204-018-2152-9
Archives of Toxicology

مصطلحات موضوعية: 0301 basic medicine, Computer science, Health, Toxicology and Mutagenesis, media_common.quotation_subject, Pharmacology toxicology, Cell Culture Techniques, Review Article, Animal Testing Alternatives, Toxicology, Appropriate use, Cosmetics, 03 medical and health sciences, 3D in vitro models, Toxicity Tests, Animals, Humans, Animal testing, Skin, media_common, Heart, General Medicine, 3. Good health, 030104 developmental biology, Liver, Risk analysis (engineering), Consumer Product Safety

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abac4eb357d91a6ac35143bd8f1341eb
https://doi.org/10.1007/s00204-018-2152-9

المؤلفون: Umair, Munawar, Leo, Rasche, Nicole, Müller, Cornelia, Vogt, Matteo, Da-Via, Larissa, Haertle, Panagiota, Arampatzi, Sascha, Dietrich, Markus, Roth, Andoni, Garitano-Trojaola, Maximilian Johannes, Steinhardt, Susanne, Strifler, Miguel, Gallardo, Joaquin, Martinez-Lopez, Ralf C, Bargou, Tobias, Heckel, Hermann, Einsele, Thorsten, Stühmer, K Martin, Kortüm, Santiago, Barrio

المصدر: Blood. 134(10)

مصطلحات موضوعية: Gene Expression Profiling, Gene Dosage, Survival Analysis, Clonal Evolution, Gene Expression Regulation, Neoplastic, Recurrence, Mutation, Disease Progression, Tumor Cells, Cultured, Humans, Tumor Suppressor Protein p53, Multiple Myeloma, Alleles, Gene Deletion, Metabolic Networks and Pathways, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::8fa22b42088842f041b0b7613dcd6d86
https://pubmed.ncbi.nlm.nih.gov/31340981

المؤلفون: Thomas Singer, Christian Klein, Sherri Dudal, Katharine Bray-French, Tobias Heckel, Tanja Fauti, Lisa J. Benincosa, Anna Maria Giusti, Sara Colombetti, Pablo Umana, Heather Hinton, Juergen Bachl, Marina Bacac, Magali Muller, Nicolas Giroud

المصدر: Journal of Immunotherapy. 39:279-289

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, CD3 Complex, T cell, Immunology, Drug Evaluation, Preclinical, Phases of clinical research, Apoptosis, Mice, Transgenic, Cross Reactions, Mice, 03 medical and health sciences, 0302 clinical medicine, Carcinoembryonic antigen, Neoplasms, Antibodies, Bispecific, Animals, Humans, Immunology and Allergy, Medicine, Drug Dosage Calculations, Cells, Cultured, Pharmacology, Clinical Trials, Phase I as Topic, Bispecific monoclonal antibody, biology, business.industry, In vitro, Carcinoembryonic Antigen, Rats, Macaca fascicularis, 030104 developmental biology, medicine.anatomical_structure, Structural Homology, Protein, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Immunotherapy, Antibody, business, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880003b5fd52980eee0ba200363562a5
https://doi.org/10.1097/cji.0000000000000132

المؤلفون: Johannes Manner, Martin Endreb, Tobias Heckel, Guido Wirtz

المصدر: UCC Companion

مصطلحات موضوعية: Computer science, business.industry, Distributed computing, media_common.quotation_subject, 020207 software engineering, Cloud computing, 02 engineering and technology, Virtualization, computer.software_genre, Hardware abstraction, Cold start, Container (abstract data type), 0202 electrical engineering, electronic engineering, information engineering, Benchmark (computing), 020201 artificial intelligence & image processing, Duration (project management), Function (engineering), business, computer, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::382bf87ade4dec370f3ecb73dccba293
https://doi.org/10.1109/ucc-companion.2018.00054

المؤلفون: Wei He, Curtis R. Warren, Wei Pan, Michael Prummer, Leonard I. Zon, Friedrich G. Kapp, Ravi Jagasia, Robert E. Gerszten, Martin Graf, Ulrich Certa, Isaac Adatto, Dorothee Kling, Klaus Christensen, Elliot L. Chaikof, Roland Jakob-Roetne, Chad A. Cowan, Eduard Urich, Ludivine Challet-Meylan, Stephanie J. Grainger, Paul L. Huang, Per-Ola Freskgard, Yulei Xia, Tobias Heckel, Mary H.C. Florido, Christoph Patsch, Lin Sun, John F. O'Sullivan, Eva C. Thoma, Roberto Iacone

المصدر: Nature cell biology
Nature Cell Biology

مصطلحات موضوعية: Vascular Endothelial Growth Factor A, KOSR, Time Factors, Transcription, Genetic, Cellular differentiation, Induced Pluripotent Stem Cells, Myocytes, Smooth Muscle, Becaplermin, Neovascularization, Physiologic, Bone Morphogenetic Protein 4, Mice, SCID, Biology, Transfection, Article, Muscle, Smooth, Vascular, Cell Line, Glycogen Synthase Kinase 3, Mice, Inbred NOD, Human Umbilical Vein Endothelial Cells, Animals, Humans, Metabolomics, Cell Lineage, Induced pluripotent stem cell, Protein Kinase Inhibitors, Wnt Signaling Pathway, Induced stem cells, Glycogen Synthase Kinase 3 beta, Dose-Response Relationship, Drug, Gene Expression Profiling, Endothelial Cells, Gene Expression Regulation, Developmental, Cell Differentiation, Proto-Oncogene Proteins c-sis, Cell Biology, Coculture Techniques, Cell biology, Endothelial stem cell, Phenotype, P19 cell, Stem cell, Biomarkers, Adult stem cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd592cca040a21a696e804399c8e712
https://doi.org/10.1038/ncb3205

المؤلفون: Hasane Ratni, Jens Lamerz, Kathleen D. McCarthy, Martin Ebeling, Hélène Meistermann, Pascale Birrer, Frédéric H.-T. Allain, Roland Schmucki, Friedrich Metzger, Gonzalo Duran-Pacheco, Sonja Meier, Sarah Khawaja, Manuel Tzouros, Angélique Augustin, Sergey Paushkin, Sébastien Campagne, Antoine Cléry, Melanie N. Hug, Thomas Luebbers, Nikos Berntenis, Manaswini Sivaramakrishnan, Sylwia Huber, Ahmed Moursy, Balazs Banfai, Nicolas Giroud, Ying Hsiu Liu, Adrian R. Krainer, Sabrina Golling, Tobias Heckel

المصدر: Nature Communications
Nature Communications, 8 (1)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Science, RNA Splicing, Exonic splicing enhancer, General Physics and Astronomy, Biology, Ligands, General Biochemistry, Genetics and Molecular Biology, Article, Piperazines, Muscular Atrophy, Spinal, 03 medical and health sciences, Transcription (biology), RNA Precursors, Biflavonoids, Humans, RNA, Messenger, lcsh:Science, Protein Structure, Quaternary, Ribonucleoprotein, Multidisciplinary, Cell-Free System, RNA, Computational Biology, RNA-Binding Proteins, Survival of motor neuron, General Chemistry, Exons, Fibroblasts, Molecular biology, Small molecule, Survival of Motor Neuron 1 Protein, Cell biology, nervous system diseases, Survival of Motor Neuron 2 Protein, 030104 developmental biology, HEK293 Cells, RNA splicing, Spliceosomes, Epoxy Compounds, lcsh:Q, Macrolides, Precursor mRNA, HeLa Cells, Protein Binding

وصف الملف: application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190ef1f34955c13bb25724e39ba9664e
http://europepmc.org/articles/PMC5684323