المؤلفون: Melissa A. Graewert, Maria Volkova, Klara Jonasson, Juha A. E. Määttä, Tobias Gräwert, Samara Mamidi, Natalia Kulesskaya, Johan Evenäs, Richard E. Johnsson, Dmitri Svergun, Arnab Bhattacharjee, Henri J. Huttunen

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/96e49cedbeaa44d2becdda52aada34c8

المؤلفون: Dmitri I. Svergun, Tobias Gräwert

المصدر: Journal of Molecular Biology. 432:3078-3092

مصطلحات موضوعية: Models, Molecular, Sample handling, 0303 health sciences, Materials science, Macromolecular Substances, Small-angle X-ray scattering, Scattering, Molecular Conformation, Computational Biology, Intrinsically disordered proteins, 03 medical and health sciences, 0302 clinical medicine, X-Ray Diffraction, Structural Biology, Scattering, Small Angle, Small peptide, Computer Simulation, Biological system, Molecular Biology, Software, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2ef8ec06560634abe610d0e5798ac1
https://doi.org/10.1016/j.jmb.2020.01.030

المؤلفون: Jonas Thelemann, Tobias Gräwert, Markus Fischer, Renato Zenobi, Anatol Schwab, Boris Illarionov, Julie G. Geist, Katharina Root, Adelbert Bacher, Konstantin Barylyuk, François Diederich

المساهمون: Zenobi, Renato [0000-0001-5211-4358], Apollo - University of Cambridge Repository

المصدر: Chemical Science, 9
Chemical Science

مصطلحات موضوعية: inorganic chemicals, 0301 basic medicine, chemistry.chemical_classification, Multiprotein complex, biology, Ligand, Stereochemistry, Electrospray ionization, technology, industry, and agriculture, Active site, General Chemistry, 0601 Biochemistry and Cell Biology, Cofactor, 3. Good health, Chemistry, 03 medical and health sciences, 030104 developmental biology, Enzyme, chemistry, biological sciences, 0302 Inorganic Chemistry, biology.protein, Homomeric, Binding site

وصف الملف: application/application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0821cd16febef64de78f6cce278e8c6
https://doi.org/10.1039/c8sc00814k

المؤلفون: Tobias Gräwert, Dmitri I. Svergun, Clement E. Blanchet, Cy M. Jeffries, Dmitry S. Molodenskiy, Melissa A. Graewert, Stefano Da Vela

المصدر: Crystals
Volume 10
Issue 11
Crystals, Vol 10, Iss 975, p 975 (2020)
Crystals 10(11), 975 (1-18) (2020). doi:10.3390/cryst10110975

مصطلحات موضوعية: Materials science, General Chemical Engineering, 030303 biophysics, Size-exclusion chromatography, small angle X-ray scattering, Light scattering, law.invention, Inorganic Chemistry, SASBDB, 03 medical and health sciences, law, laser light scattering, lcsh:QD901-999, data quality, General Materials Science, Spectroscopy, 030304 developmental biology, 0303 health sciences, Scattering, Small-angle X-ray scattering, DESY, size exclusion chromatography, benchmarked datasets, Condensed Matter Physics, Synchrotron, Computational physics, ddc:540, lcsh:Crystallography, Small-angle scattering

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1be66682c811f57f345d275c073e82e

المؤلفون: Markus Fischer, Tobias Gräwert, Alexandra Siemens, Sonja Schüssler, Ilka Haase, Adelbert Bacher, Markus Perbandt, Boris Illarionov, Klaus Richter

المصدر: Acta Crystallographica. Section F, Structural Biology Communications
Acta crystallographica / F Structural biology communications Section F 75(9), 586-592 (2019). doi:10.1107/S2053230X19010902

مصطلحات موضوعية: crystal structure, GTP', GTP cyclohydrolase I, Protein Conformation, High-throughput screening, Biophysics, medicine.disease_cause, Crystallography, X-Ray, Biochemistry, Neopterin, high-throughput screening, law.invention, Research Communications, Small Molecule Libraries, 03 medical and health sciences, Listeria monocytogenes, Bacterial Proteins, listeriosis, Structural Biology, law, Genetics, medicine, Escherichia coli, ddc:530, Molecular replacement, GTP Cyclohydrolase, 030304 developmental biology, 0303 health sciences, tetrahydrofolate biosynthesis, biology, Strain (chemistry), 030306 microbiology, Chemistry, Condensed Matter Physics, Recombinant Proteins, ddc, Anti-Bacterial Agents, Open reading frame, Recombinant DNA, biology.protein

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec89e3fc3caae88f0256a8937f639f93
https://pubmed.ncbi.nlm.nih.gov/31475925

المؤلفون: Tobias Gräwert, Boris Illarionov, Markus Fischer, Thomas Kurz, Sergio Wittlin, Claudia Lienau, Benjamin Mordmüller, Adelbert Bacher, Louis Maes, Christoph T. Behrendt, Jana Held, Karin Brücher, Sarah Konzuch

المصدر: Journal of medicinal chemistry

مصطلحات موضوعية: Cell Survival, Plasmodium berghei, Plasmodium falciparum, Mice, SCID, Pharmacology, Antimalarials, Mice, Structure-Activity Relationship, Fosfomycin, In vivo, parasitic diseases, Drug Discovery, medicine, Animals, Humans, Moiety, Prodrugs, Cytotoxicity, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Pharmacology. Therapy, Prodrug, biology.organism_classification, Fosmidomycin, In vitro, Malaria, Disease Models, Animal, Biochemistry, Molecular Medicine, HeLa Cells, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d428904427c873d6447f76da1ff1e3
https://doi.org/10.1021/jm5019719

المؤلفون: Silke Marsch, Markus Fischer, Michael Vogeser, Tobias Gräwert, Dietrich Seidel, Adelbert Bacher, Ulrike Bacher, Harald Mückter, Christian Ettenhuber, Ralf Laupitz, Wolfgang Eisenreich

المصدر: Isotopes in Environmental and Health Studies. 51:11-23

مصطلحات موضوعية: Blood Glucose, Male, Carbon Isotopes, Magnetic Resonance Spectroscopy, Chemistry, Citric Acid Cycle, Carbon-13, Pilot Projects, Carbon-13 NMR, Carbohydrate metabolism, Pentose phosphate pathway, Pentose Phosphate Pathway, Inorganic Chemistry, Citric acid cycle, chemistry.chemical_compound, Biochemistry, Humans, Environmental Chemistry, Glycolysis, Anaplerotic reactions, Isotopologue, General Environmental Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0340dec138cb2d0c90ecdf050eed4d88
https://doi.org/10.1080/10256016.2014.1001845

المؤلفون: Beate Lungerich, Lasse van Geelen, Leandro A. Alves Avelar, Claudia Lienau, Rainer Kalscheuer, Benjamin Mordmüller, Mirko Buchholz, Ulrich Riederer, Holger Cynis, Tobias Gräwert, Markus Fischer, Dieter Meier, Boris Illarionov, Tanja C. Knaab, Stefanie Geissler, Jana Held, Thomas Kurz, Adelbert Bacher

المساهمون: Publica

المصدر: European Journal of Medicinal Chemistry. 181:111555

مصطلحات موضوعية: Stereochemistry, Plasmodium falciparum, Antiprotozoal Agents, Microbial Sensitivity Tests, medicine.disease_cause, 01 natural sciences, HeLa, Mycobacterium tuberculosis, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Fosfomycin, Parasitic Sensitivity Tests, parasitic diseases, Drug Discovery, Escherichia coli, medicine, Humans, Racemization, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, Xylulose, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Organic Chemistry, General Medicine, biology.organism_classification, Fosmidomycin, Anti-Bacterial Agents, 0104 chemical sciences, Enzyme, chemistry, Caco-2 Cells, HeLa Cells, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6ace739ec3d82720492527907c6654
https://doi.org/10.1016/j.ejmech.2019.07.058

المؤلفون: Tobias Gräwert, Ingrid Span, Adelbert Bacher, Michael Groll

المصدر: Angewandte Chemie. 122:8984-8991

مصطلحات موضوعية: Chemistry, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8588c9ef24883f21de5880a8d8db4d98
https://doi.org/10.1002/ange.201000833

المؤلفون: Markus Fischer, José L. Alonso-Gómez, Boris Illarionov, François Diederich, W. Bernd Schweizer, Victoria Illarionova, Michael Groll, Tobias Gräwert, Sergio Wittlin, Susan Lauw, Felix Rohdich, Adelbert Bacher, Wolfgang Eisenreich, Christian Scheurer, Julie G. Geist, Johannes Kaiser

المصدر: CHEMMEDCHEM

مصطلحات موضوعية: Tuberculosis, Plasmodium falciparum, Arabidopsis, Molecular Conformation, Protozoan Proteins, 01 natural sciences, Biochemistry, Microbiology, Small Molecule Libraries, Mycobacterium tuberculosis, Antimalarials, 03 medical and health sciences, Bacterial Proteins, parasitic diseases, Drug Discovery, medicine, Arabidopsis thaliana, Enzyme Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, Non-mevalonate pathway, 030304 developmental biology, Pharmacology, 0303 health sciences, ATP synthase, biology, 010405 organic chemistry, Organic Chemistry, biology.organism_classification, medicine.disease, Recombinant Proteins, Anti-Bacterial Agents, 3. Good health, 0104 chemical sciences, Red blood cell, Pyrimidines, medicine.anatomical_structure, biology.protein, Molecular Medicine, Phosphorus-Oxygen Lyases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c09cc43a44a5acc9b617e411bb8ee33
https://doi.org/10.1002/cmdc.201000083

المؤلفون: Ingrid Span, Wolfgang Eisenreich, Jörg Eppinger, Michael Groll, Tobias Gräwert, Felix Rohdich, Adelbert Bacher

المصدر: Angewandte Chemie. 121:5867-5870

مصطلحات موضوعية: Chemistry, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::361733f97846e9b870ada46c6ac92a43
https://doi.org/10.1002/ange.200900548

المؤلفون: Felix Rohdich, Christoph Rieder, Erik Schleicher, Ralf Laupitz, Duilio Arigoni, Martin Haslbeck, Sabine Amslinger, Tobias Gräwert, Stefan Hecht, Stefan Weber, Ferdinand Zepeck, Nicholas Schramek, Adelbert Bacher, Wolfgang Eisenreich, Johannes Kaiser, Johannes Buchner

المصدر: Journal of the American Chemical Society. 126:12847-12855

مصطلحات موضوعية: Iron-Sulfur Proteins, Flavodoxin, Operon, Stereochemistry, Iron–sulfur cluster, medicine.disease_cause, Biochemistry, Catalysis, Enzyme catalysis, chemistry.chemical_compound, Colloid and Surface Chemistry, Escherichia coli, medicine, Nuclear Magnetic Resonance, Biomolecular, chemistry.chemical_classification, biology, Escherichia coli Proteins, Electron Spin Resonance Spectroscopy, General Chemistry, Recombinant Proteins, Amino acid, Enzyme Activation, Enzyme, chemistry, Mutagenesis, Site-Directed, biology.protein, Spectrophotometry, Ultraviolet, Oxidoreductases, Plasmids, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855140d6e3e25b70d630bbfb93688eb4
https://doi.org/10.1021/ja0471727

المؤلفون: Stefan Hecht, Adelbert Bacher, Felix Rohdich, Petra Adam, Tobias Gräwert, Duilio Arigoni, Wolfgang Eisenreich, Johannes Kaiser, Sabine Amslinger, Ralf Laupitz, Ferdinand Zepeck

المصدر: Proceedings of the National Academy of Sciences. 100:1586-1591

مصطلحات موضوعية: Flavodoxin, Blotting, Western, Protein domain, Mutant, Catalysis, Chromatography, Affinity, law.invention, Xylulose, Maltose-binding protein, Bacterial Proteins, Polyisoprenyl Phosphates, law, Escherichia coli, Bioorganic chemistry, Nuclear Magnetic Resonance, Biomolecular, Multidisciplinary, biology, Chemistry, Escherichia coli Proteins, Biological Sciences, Fusion protein, Transformation (genetics), Biochemistry, biology.protein, Recombinant DNA, Oxidoreductases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b71e8f9241911c80883fdadf2764da7
https://doi.org/10.1073/pnas.0337742100

المؤلفون: Tobias Gräwert, Hans-Peter Hohmann, Maik Kindermann, Markus Fischer, Stephane Duval, Adelbert Bacher

المصدر: Journal of agricultural and food chemistry. 62(52)

مصطلحات موضوعية: animal structures, Methanobrevibacter ruminantium, Rumen, biology, Methanogenesis, Atmospheric methane, Archaeal Proteins, General Chemistry, Reductase, Methanobrevibacter, biology.organism_classification, Methane, chemistry.chemical_compound, Kinetics, Methyl CoM reductase, Biochemistry, chemistry, Alkanesulfonic Acids, Ruminant, Animals, Cattle, General Agricultural and Biological Sciences, Oxidoreductases, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3399b33e44117f1ad4afa61e47fa9e
https://pubmed.ncbi.nlm.nih.gov/25483006

المؤلفون: Ilka, Haase, Tobias, Gräwert, Boris, Illarionov, Adelbert, Bacher, Markus, Fischer

المصدر: Methods in molecular biology (Clifton, N.J.). 1146

مصطلحات موضوعية: Riboflavin Synthase, Anti-Infective Agents, Gene Expression Regulation, Flavin Mononucleotide, Multienzyme Complexes, Riboflavin, Fermentation, Flavin-Adenine Dinucleotide, Animals, Brucella Vaccine, Humans, Biosynthetic Pathways

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9ba8960fe1fc31ea6e2ee5fbdb3f5086
https://pubmed.ncbi.nlm.nih.gov/24764086

المؤلفون: Boris Illarionov, Adelbert Bacher, Ilka Haase, Tobias Gräwert, Markus Fischer

المصدر: Methods in Molecular Biology ISBN: 9781493904518

مصطلحات موضوعية: chemistry.chemical_classification, biology, ATP synthase, GTP', Ribulose, Phosphatase, Riboflavin, Riboflavin synthase, chemistry.chemical_compound, Enzyme, Biochemistry, chemistry, biology.protein, Fermentation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0654949fb789eca772d530c9b21502c6
https://doi.org/10.1007/978-1-4939-0452-5_2

المؤلفون: Ulrich Riederer, Jana Held, Philipp Werner, Andrea Kunfermann, Christoph T. Behrendt, Claudia Lienau, Boris Illarionov, Michael Groll, Markus Fischer, Thomas Kurz, Tobias Gräwert, Adelbert Bacher, Benjamin Mordmüller, Wolfgang Eisenreich, Saskia Hähn

المصدر: Journal of medicinal chemistry. 56(20)

مصطلحات موضوعية: Drug, Models, Molecular, media_common.quotation_subject, Molecular Sequence Data, Plasmodium falciparum, Protozoan Proteins, Pharmacology, Crystallography, X-Ray, Human health, Anti-Infective Agents, Bacterial Proteins, Fosfomycin, parasitic diseases, Drug Discovery, medicine, Escherichia coli, Amino Acid Sequence, Aldose-Ketose Isomerases, media_common, Molecular Structure, Sequence Homology, Amino Acid, Chemistry, Drug discovery, Stereoisomerism, Mycobacterium tuberculosis, Fosmidomycin, Protein Structure, Tertiary, Metabolic pathway, Sequence homology, Biochemistry, Structural biology, Models, Chemical, Molecular Medicine, Enantiomer, medicine.drug, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec660c7bb007add3c2ba3568fb28e3d
https://pubmed.ncbi.nlm.nih.gov/24032981

المؤلفون: Markus Fischer, Tobias Gräwert, Adelbert Bacher

المصدر: IUBMB life. 65(4)

مصطلحات موضوعية: GTP', Stereochemistry, Cations, Divalent, GTP cyclohydrolase I, Riboflavin, Clinical Biochemistry, Biopterin, Queuosine, Guanosine triphosphate, Biochemistry, Cofactor, chemistry.chemical_compound, Folic Acid, Genetics, medicine, Escherichia coli, Humans, GTP Cyclohydrolase, Molecular Biology, Toxoflavin, biology, Cell Biology, Tetrahydrobiopterin, Anti-Bacterial Agents, Kinetics, chemistry, biology.protein, Guanosine Triphosphate, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89152b7aa5acbad43a6cce63b5c67826
https://pubmed.ncbi.nlm.nih.gov/23457054

المؤلفون: Wolfgang Eisenreich, Tobias Gräwert, Ingrid Span, Adelbert Bacher, Michael Groll

المصدر: Journal of molecular biology. 416(1)

مصطلحات موضوعية: Iron-Sulfur Proteins, Reaction mechanism, Stereochemistry, Protein Conformation, Mutant, Protein Data Bank (RCSB PDB), Crystal structure, Crystallography, X-Ray, Catalysis, chemistry.chemical_compound, Structure-Activity Relationship, Hemiterpenes, Organophosphorus Compounds, Structural Biology, Oxidoreductase, Catalytic Domain, Escherichia coli, Hydroxymethyl, Non-mevalonate pathway, Molecular Biology, chemistry.chemical_classification, Chemistry, Terpenes, Escherichia coli Proteins, Substrate (chemistry), Water, Organophosphates, Mutant Proteins, Oxidoreductases, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ecdeff3d7f258fd74a0207d26c149c
https://pubmed.ncbi.nlm.nih.gov/22137895

المؤلفون: Tobias Gräwert, Wolfgang Eisenreich, Michael Groll, Miriam Pein, Andrea Kunfermann, An Matheeussen, Adelbert Bacher, Victoria Illarionova, Boris Illarionov, Johannes Kaiser, Markus Fischer, Thomas Kurz, Christoph T. Behrendt, Louis Maes

المصدر: Journal of medicinal chemistry

مصطلحات موضوعية: Models, Molecular, Erythrocytes, Plasmodium berghei, Drug target, Plasmodium falciparum, Crystallography, X-Ray, Antimalarials, Mice, Structure-Activity Relationship, Fosfomycin, Parasitic Sensitivity Tests, In vivo, Multienzyme Complexes, Divalent metal ions, Drug Discovery, medicine, Animals, Humans, Aldose-Ketose Isomerases, chemistry.chemical_classification, Molecular Structure, Chemistry, Pharmacology. Therapy, Fosmidomycin, Malaria, Isoprenoid biosynthesis, Enzyme, Biochemistry, Molecular Medicine, Oxidoreductases, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92f13335115c2d8e34e7df2fe4825f7
https://pubmed.ncbi.nlm.nih.gov/21866890