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1Academic Journal
المؤلفون: Palle Serup, Carsten Gustavsen, Tino Klein, Leah A. Potter, Robert Lin, Nandita Mullapudi, Ewa Wandzioch, Angela Hines, Ashley Davis, Christine Bruun, Nina Engberg, Dorthe R. Petersen, Janny M. L. Peterslund, Raymond J. MacDonald, Anne Grapin-Botton, Mark A. Magnuson, Kenneth S. Zaret
المصدر: Disease Models & Mechanisms, Vol 5, Iss 6, Pp 956-966 (2012)
وصف الملف: electronic resource
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2
المؤلفون: Signe Horn, Tino Klein, Mette C. Jørgensen, Jonas Ahnfelt-Rønne, Young-Yun Kong, Mark A. Magnuson, Heiko Lickert, Jill Lindner, Jan N. Jensen, Moritz Gegg, Sune Kobberup, Palle Serup, Ryoichiro Kageyama, Mark Kalisz
المصدر: Proc. Natl. Acad. Sci. U.S.A. 109, 7356-7361 (2012)
مصطلحات موضوعية: Male, Diabetes, Lateral Signaling, Tip, Trunk, Time Factors, Ubiquitin-Protein Ligases, Blotting, Western, Notch signaling pathway, Mice, Transgenic, Nerve Tissue Proteins, Enteroendocrine cell, Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Insulin-Secreting Cells, Basic Helix-Loop-Helix Transcription Factors, medicine, Acinar cell, Animals, Cell Lineage, Progenitor cell, HES1, Pancreas, Transcription factor, Hepatocyte Nuclear Factor 1-beta, 030304 developmental biology, Homeodomain Proteins, Mice, Knockout, 0303 health sciences, Multidisciplinary, Receptors, Notch, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Regulation, Developmental, Nuclear Proteins, Biological Sciences, Embryo, Mammalian, Molecular biology, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, Mutation, Hepatocyte Nuclear Factor 3-beta, Female, Signal transduction, 030217 neurology & neurosurgery, Signal Transduction, Transcription Factors
وصف الملف: application/pdf
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3
المؤلفون: Rodrigo S. Garcia, Poul Hyttel, Tino Klein, Xenia Asbæk Wolf, Palle Serup
المصدر: Gene Expression Patterns. 12:85-93
مصطلحات موضوعية: Primitive Streak, Transcription, Genetic, Green Fluorescent Proteins, Eomesodermin, Biology, Mesoderm, Mice, Genetics, medicine, Animals, RNA, Messenger, Molecular Biology, Cells, Cultured, Conserved Sequence, Regulation of gene expression, Primitive streak, Endoderm, Gastrulation, Embryogenesis, Gene Expression Regulation, Developmental, Cell Differentiation, Embryo, Mammalian, Immunohistochemistry, Molecular biology, Activins, medicine.anatomical_structure, Epiblast, embryonic structures, T-Box Domain Proteins, Developmental Biology, Definitive endoderm
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المؤلفون: Stoyan G. Petkov, Hendrik Marks, Tino Klein, Rodrigo S. Garcia, Poul Hyttel, Henk Stunnenberg, Yu Gao
المصدر: Stem Cell Research
Stem Cell Research; Vol 6
Stem Cell Research, 6, 226-237
Stem Cell Research, 6, 3, pp. 226-237مصطلحات موضوعية: Homeobox protein NANOG, Embryonic Germ Cells, Swine, Cellular differentiation, Cell Culture Techniques, Embryoid body, Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, SOX2, Pregnancy, Animals, Molecular Biology, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries), Cells, Cultured, Embryonic Stem Cells, 030304 developmental biology, Medicine(all), 0303 health sciences, Gene Expression Regulation, Developmental, Cell Differentiation, Cell Biology, General Medicine, Embryo, Mammalian, Embryonic stem cell, Molecular biology, Gene expression profiling, Cell culture, Swine, Miniature, Female, 030217 neurology & neurosurgery, Transcription Factors, Developmental Biology
وصف الملف: application/pdf
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5
المؤلفون: Peter Brøgger, Lars Aagaard, H. D. Pedersen, Peter Bross, Sif Groth Rønn, Tino Klein, Charlotte Brandt Sørensen, Trine Skov Petersen, Rasha Abdelkadhem Al-Saaidi, Yan Zhou, Dianna Hussmann, Yonglun Luo, Yong Liu, Anders Lade Nielsen, Guangqian Zhou, Lin Lin, Shuang Tan, Lars Bolund
المصدر: Zhou, Y, Liu, Y, Hussmann, D, Brøgger, P, Al-Saaidi, R A, Tan, S, Lin, L, Petersen, T S, Zhou, G Q, Bross, P, Aagaard, L, Klein, T, Rønn, S G, Pedersen, H D, Bolund, L, Nielsen, A L, Sørensen, C B & Luo, Y 2016, ' Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system ', Cellular and Molecular Life Sciences, vol. 73, no. 13, pp. 2543-63 . https://doi.org/10.1007/s00018-015-2128-3
مصطلحات موضوعية: 0301 basic medicine, Chromosomal Proteins, Non-Histone, Swine, Golden Gate Cloning, Genetic Vectors, Computational biology, Biology, Fluorescence, Genome engineering, Receptor, IGF Type 1, 03 medical and health sciences, Cellular and Molecular Neuroscience, Gene Knockout Techniques, Genome editing, Genes, Reporter, Transcription Activator-Like Effector Nucleases, CRISPR, Animals, Humans, Clustered Regularly Interspaced Short Palindromic Repeats, Homologous Recombination, Molecular Biology, Gene, Cells, Cultured, Pharmacology, Genetics, Gene Editing, Transcription activator-like effector nuclease, Cas9, Gene targeting, Receptors, Somatomedin, Cell Biology, Fibroblasts, 030104 developmental biology, HEK293 Cells, Chromobox Protein Homolog 5, MCF-7 Cells, Molecular Medicine, CRISPR-Cas Systems
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6
المؤلفون: Tino Klein, R. Scott Heller, Palle Serup, Harry Heimberg, Zhidong Ling, Ole D. Madsen
المساهمون: Medical Biochemistry, Pathologic Biochemistry and Physiology
المصدر: Vrije Universiteit Brussel
مصطلحات موضوعية: Adult, 0301 basic medicine, CD31, medicine.medical_specialty, Pathology, Histology, CD34, Connective tissue, Nerve Tissue Proteins, Vimentin, macromolecular substances, Cholangiocyte, Nestin, Islets of Langerhans, 03 medical and health sciences, Intermediate Filament Proteins, Internal medicine, medicine, Humans, Pancreas, reproductive and urinary physiology, 030102 biochemistry & molecular biology, biology, Pancreatic Ducts, Endoglin, Immunohistochemistry, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, nervous system, embryonic structures, biology.protein, Anatomy
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المؤلفون: Ole D. Madsen, M Katoh, Rs Heller, Palle Serup, Tino Klein, Harry Heimberg, Zhidong Ling
المساهمون: Medical Biochemistry, Pathologic Biochemistry and Physiology
المصدر: Vrije Universiteit Brussel
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Cell signaling, Frizzled, Adolescent, Gene Expression, In situ hybridization, Biology, Article, Wnt2 Protein, Islets of Langerhans, Proto-Oncogene Proteins, Internal medicine, Genetics, medicine, Animals, Humans, Insulin, Receptor, Pancreas, Molecular Biology, In Situ Hybridization, Reverse Transcriptase Polymerase Chain Reaction, Wnt signaling pathway, Membrane Proteins, Proteins, LRP6, LRP5, Middle Aged, Zebrafish Proteins, Glucagon, Frizzled Receptors, Neoplasm Proteins, Cell biology, Wnt Proteins, Endocrinology, Intercellular Signaling Peptides and Proteins, RNA, Female, Signal transduction
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8
المؤلفون: Tino Klein, Palle Serup, R S Heller, Ulrik Frandsen
المصدر: Archives of Biochemistry and Biophysics. 395:259-263
مصطلحات موضوعية: endocrine system, medicine.medical_specialty, Cellular differentiation, Biophysics, Mice, Transgenic, Nerve Tissue Proteins, Enteroendocrine cell, Biology, Biochemistry, Collagen Type I, Cell Line, Mice, Glucagon-Like Peptide 1, Endocrine Glands, Internal medicine, Basic Helix-Loop-Helix Transcription Factors, medicine, Animals, Insulin, RNA, Messenger, Molecular Biology, Inhibin-beta Subunits, Homeodomain Proteins, Betacellulin, Reverse Transcriptase Polymerase Chain Reaction, Stem Cells, Temperature, Cell Differentiation, Liraglutide, Glucagon, Activins, Cell biology, Endothelial stem cell, Endocrinology, Cell culture, Trans-Activators, PDX1, Cattle, Collagen, Stem cell, Endocrine gland
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المؤلفون: Ulrich Weser, Tino Klein, Gaohua Liu, Ivano Bertini, Claudio Luchinat, Hans-Jürgen Hartmann
المصدر: European Journal of Biochemistry. 267:1008-1018
مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_element, Nuclear magnetic resonance spectroscopy, Biochemistry, Copper, Amino acid, chemistry.chemical_compound, Crystallography, chemistry, Heteronuclear molecule, Metallothionein, Spectroscopy, Derivative (chemistry), Cysteine
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10
المؤلفون: Sonja-Verena Albers, Hans Peter Arnold, Jan Hiort, Tino Klein, David Prangishvili, Wolfram Zillig, Anja Schweier, Jakob K. Kristjansson, Harpreet Singh, Ingelore Holz, Kenneth M. Stedman
المصدر: Plasmid. 40:190-202
مصطلحات موضوعية: DNA, Bacterial, Genetics, Bacteriological Techniques, biology, ved/biology, Thermophile, Sulfolobus solfataricus, ved/biology.organism_classification_rank.species, biology.organism_classification, Genome, Clone Cells, Sulfolobus, chemistry.chemical_compound, Plasmid, chemistry, Conjugation, Genetic, Molecular Biology, Gene, DNA, Plasmids, Sequence Deletion, Archaea
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11
المؤلفون: Angela Hines, Mark A. Magnuson, Tino Klein, Palle Serup, Leah A. Potter, Christine Bruun, Ashley Davis, Ewa Wandzioch, Nandita Mullapudi, Dorthe Rønn Petersen, Carsten Gustavsen, Janny M.L. Peterslund, Raymond J. MacDonald, Kenneth S. Zaret, Robert Lin, Nina Engberg, Anne Grapin-Botton
المصدر: Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 5, Iss 6, Pp 956-966 (2012)مصطلحات موضوعية: RNA, Untranslated, Transcription, Genetic, Molecular Sequence Data, Neuroscience (miscellaneous), Medicine (miscellaneous), lcsh:Medicine, Tretinoin, Biology, Bone morphogenetic protein, Response Elements, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Immunology and Microbiology (miscellaneous), Transcription (biology), Extracellular, lcsh:Pathology, Animals, Humans, Resource Article, Promoter Regions, Genetic, Wnt Signaling Pathway, Embryonic Stem Cells, 030304 developmental biology, Sequence Deletion, Genetics, Recombination, Genetic, 0303 health sciences, Base Sequence, Receptors, Notch, Recombinase-mediated cassette exchange, lcsh:R, Wnt signaling pathway, Proteins, Embryo, Mammalian, Embryonic stem cell, Cell biology, Activins, Rats, Regulatory sequence, Genetic Loci, Bone Morphogenetic Proteins, Mutation, Signal transduction, Genetic Engineering, 030217 neurology & neurosurgery, lcsh:RB1-214, Signal Transduction
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12Academic Journal
المؤلفون: Tino Klein
المساهمون: Yves Heremans
الاتاحة: https://biblio.vub.ac.be/vubir/investigation-and-characterization-of-the-duct-cellenriching-process-during-serumfree-suspension-and-monolayer-culture-using-the-human-exocrine-pancreas-fraction(da4baa08-51b1-40ed-88c3-4b00d0a3123b).html
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13
المؤلفون: Tino Klein, Mattias Hansson, Janny M.L. Peterslund, Palle Serup, Maria Winzi, Morten Kahn, Poul Maddox-Hyttel, Nina Engberg, Dorthe R. Olesen
المصدر: Hansson, M, Olesen, D R, Peterslund, J M L, Engberg, N, Kahn, M Ø, Winzi, M K, Klein, T, Serup, P & Maddox-Hyttel, P 2009, ' A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells ', Advances in Developmental Biology, vol. 330, no. 2, pp. 286-304 . https://doi.org/10.1016/j.ydbio.2009.03.026
مصطلحات موضوعية: TGF-β, endocrine system, animal structures, Cellular differentiation, Fluorescent Antibody Technique, Chick Embryo, Biology, Fibroblast growth factor, Article, FGF and mesoderm formation, Wnt, Mice, medicine, FGF, Animals, Anterior–posterior patterning, RNA, Small Interfering, Molecular Biology, Cells, Cultured, Embryonic Stem Cells, Base Sequence, Primitive streak, Reverse Transcriptase Polymerase Chain Reaction, Gastrulation, Endoderm, Wnt signaling pathway, Mesendoderm, Cell Differentiation, Cell Biology, Flow Cytometry, Molecular biology, Activins, Fibroblast Growth Factors, Wnt Proteins, Embryonic stem cell, medicine.anatomical_structure, DKK1, embryonic structures, Developmental Biology, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3419e91851c857cdcc3d58955d0719ca
https://pure.au.dk/portal/da/publications/a-late-requirement-for-wnt-and-fgf-signaling-during-activininduced-formation-of-foregut-endoderm-from-mouse-embryonic-stem-cells(6ef62be2-86f3-4973-a8fc-3525f5fe9d60).html -
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المؤلفون: G. Christofori, Tino Klein, Christian Boitard, Amnon Peled, Yinon Ben-Neriah, Roy Eldor, A. Yeffet, Danielle Melloul, J. C. Carel, P. Serup, V. Doviner, D. L. Eizirik, D. Amar, K. Baum
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 103(13)
مصطلحات موضوعية: medicine.medical_specialty, Active Transport, Cell Nucleus, Drug Resistance, Apoptosis, Mice, Transgenic, Biology, Gene Expression Regulation, Enzymologic, Streptozocin, Diabetes Mellitus, Experimental, Tissue Culture Techniques, chemistry.chemical_compound, Interferon-gamma, Islets of Langerhans, Mice, In vivo, Internal medicine, medicine, Animals, Lymphocytes, Transcription factor, Multidisciplinary, Pancreatic islets, I-Kappa-B Kinase, NF-kappa B, NF-κB, DNA, Biological Sciences, NFKB1, I-kappa B Kinase, Endocrinology, medicine.anatomical_structure, chemistry, Doxycycline, Mutation, Cancer research, Cytokines, Beta cell, Interleukin-1, Protein Binding
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15
المؤلفون: Yves Heremans, Tino Klein, Ole D. Madsen, R. Scott Heller, Palle Serup, Harry Heimberg, Daniel Pipeleers
المساهمون: Beta Cell Neogenesis, Pathologic Biochemistry and Physiology
المصدر: Vrije Universiteit Brussel
مصطلحات موضوعية: Adult, Vascular Endothelial Growth Factor A, medicine.medical_specialty, Time Factors, Endocrinology, Diabetes and Metabolism, human exocrine pancreas fraction, Apoptosis, Enteroendocrine cell, Pregnancy Proteins, Culture Media, Serum-Free, chemistry.chemical_compound, Endocrinology, Internal medicine, Cell Adhesion, Internal Medicine, medicine, Acinar cell, Humans, Cells, Cultured, Cell Proliferation, Placenta Growth Factor, Hepatology, diabetes, Cell growth, Chemistry, Transdifferentiation, Pancreatic Ducts, Endothelial Cells, Fibroblasts, Middle Aged, Coculture Techniques, Pancreas, Exocrine, Cell biology, Vascular endothelial growth factor, Endothelial stem cell, Vascular endothelial growth factor A, medicine.anatomical_structure, Cell Transdifferentiation, Duct (anatomy), Biomarkers
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