المؤلفون: Guillem Pascual-Pasto, Brendan McIntyre, Margaret G. Hines, Anna M. Giudice, Laura Garcia-Gerique, Jennifer Hoffmann, Pamela Mishra, Stephanie Matlaga, Simona Lombardi, Rawan Shraim, Patrick M. Schürch, Mark Yarmarkovich, Ted J. Hofmann, Fatemeh Alikarami, Daniel Martinez, Matthew Tsang, Luis Gil-de-Gómez, Timothy T. Spear, Kathrin M. Bernt, Adam J. Wolpaw, Dimiter S. Dimitrov, Wei Li, Kristopher R. Bosse

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/b2ad4e5f753a46548b7df6730192b457

المؤلفون: Kendra C. Foley, Timothy T. Spear, David C. Murray, Kaoru Nagato, Elizabeth Garrett-Mayer, Michael I. Nishimura

المصدر: Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 105-115 (2017)

مصطلحات موضوعية: tumor immunology, gene-modified T cells, adoptive cell transfer, TCR pairing, TCR modifications, enhanced TCR expression, immunotherapy, cancer immunotherapy, cellular therapy, gene therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770517300232; https://doaj.org/toc/2372-7705

URL الوصول: https://doaj.org/article/3189595fbbd7476cb5193f7c6d87a5a8

المؤلفون: Long Chen, David F Stroncek, Gang Zeng, Steven Highfill, Robert Reger, Stefan Barisic, Elena Cherkasova, Elizabeth M Brahmbhatt, Timothy T Spear, Ujjawal Savani, Stephanie Pierre, Gina M Scurti, Muna Igboko, Rosa Nadal, Gordon Parry, Annika V Dalheim, Michael I Nishimura, Richard W Childs

المصدر: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: https://jitc.bmj.com/content/12/9/e009147.full; https://doaj.org/toc/2051-1426; https://doaj.org/article/bdd7b926eb5a41dab026790fbcaa4b31

الاتاحة: https://doi.org/10.1136/jitc-2024-009147
https://doaj.org/article/bdd7b926eb5a41dab026790fbcaa4b31

المؤلفون: Michael I. Nishimura, Brian M. Baker, Brian D. Evavold, Timothy T. Spear

المصدر: Cancer Immunology, Immunotherapy. 68:1881-1889

مصطلحات موضوعية: Cytotoxicity, Immunologic, Cancer Research, Adoptive cell transfer, T-Lymphocytes, T cell, medicine.medical_treatment, Immunology, Mutagenesis (molecular biology technique), T-Cell Antigen Receptor Specificity, Cross Reactions, Biology, medicine.disease_cause, Cross-reactivity, 03 medical and health sciences, 0302 clinical medicine, Cancer immunotherapy, Antibody Specificity, Neoplasms, medicine, Animals, Humans, Immunology and Allergy, Effector, T-cell receptor, Cancer, medicine.disease, Genes, T-Cell Receptor, medicine.anatomical_structure, Oncology, Cancer research, Immunotherapy, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e1ec0e70cbc5656f594a2f8af4dcfd
https://doi.org/10.1007/s00262-019-02401-0

المؤلفون: Yuan Wang, Lance M. Hellman, Thomas W. Smith, Brian M. Baker, Michael I. Nishimura, Timothy T. Spear, Patricia E. Simms, Elizabeth Garrett-Mayer

المصدر: Molecular Therapy. 26:996-1007

مصطلحات موضوعية: Cytotoxicity, Immunologic, Models, Molecular, 0301 basic medicine, Adoptive cell transfer, Protein Conformation, T-Lymphocytes, T cell, Receptors, Antigen, T-Cell, Ligands, Lymphocyte Activation, Major histocompatibility complex, Immunotherapy, Adoptive, Immunophenotyping, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, T-Lymphocyte Subsets, Interferon, Histocompatibility Antigens, Drug Discovery, Genetics, medicine, Humans, Molecular Biology, Cells, Cultured, Pharmacology, Receptors, Chimeric Antigen, biology, T-cell receptor, Histocompatibility, Phenotype, 030104 developmental biology, medicine.anatomical_structure, Lytic cycle, Peripheral blood lymphocyte, Immunology, biology.protein, Cytokines, Molecular Medicine, Original Article, Peptides, Biomarkers, Protein Binding, 030215 immunology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b119e213f5e8d590c90883796e77ed9
https://doi.org/10.1016/j.ymthe.2018.01.015

المؤلفون: Timothy T. Spear, Kaoru Nagato, Michael I. Nishimura

المصدر: Cancer Immunology, Immunotherapy. 65:631-649

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Recombinant Fusion Proteins, T-Lymphocytes, medicine.medical_treatment, T cell, Immunology, Adoptive immunotherapy, Receptors, Antigen, T-Cell, Computational biology, Biology, Immunotherapy, Adoptive, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Cancer immunotherapy, Antigens, Neoplasm, Neoplasms, medicine, Animals, Humans, Immunology and Allergy, Clinical Trials as Topic, Genetically engineered, T-Cell Specificity, Cancer, Immunotherapy, medicine.disease, Treatment Outcome, 030104 developmental biology, medicine.anatomical_structure, Oncology, Cytokines, Genetic Engineering, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8a3c3885b39e7e118f4a97b14e21af
https://doi.org/10.1007/s00262-016-1842-5

المؤلفون: Elizabeth Garrett-Mayer, Jeffrey J. Roszkowski, Glenda G. Callender, Timothy T. Spear, Michael I. Nishimura, Makio Iwashima, Yuan Wang, Patricia E. Simms, Kendra C. Foley, Lance M. Hellman, Rachel H. McMahan, Brian M. Baker, Gina Scurti, Timothy P. Riley, Gretchen E. Lyons, Hugo R. Rosen, David C. Murray

المصدر: Journal of Leukocyte Biology. 100:545-557

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, T cell, Immunology, Receptors, Antigen, T-Cell, Epitopes, T-Lymphocyte, chemical and pharmacologic phenomena, Hepacivirus, CD8-Positive T-Lymphocytes, Cross Reactions, Major histocompatibility complex, Genomic Instability, Epitope, 03 medical and health sciences, Antigen, medicine, Humans, Immunology and Allergy, Antigens, Viral, Genetics, biology, Histocompatibility Antigens Class I, T-cell receptor, Cell Biology, Immunotherapy, Hepatitis C, Virology, Receptors, Signal Transduction, & Genes, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Antibody, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7812bd4b032ab30b8988a27394e7b2
https://doi.org/10.1189/jlb.2a1215-561r

المؤلفون: Jeffrey J. Roszkowski, Michael I. Nishimura, Kendra C. Foley, Glenda G. Callender, Alexander Langerman, Timothy T. Spear, Mingli Li, Elizabeth Garrett-Mayer, Yi Zhang, Gina Scurti, Patricia E. Simms, David C. Murray, Justin T. Thomas, Kelly Moxley

المصدر: Cancer Immunology, Immunotherapy. 65:293-304

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Adoptive cell transfer, Carcinoma, Hepatocellular, T-Lymphocytes, Hepatitis C virus, medicine.medical_treatment, T cell, Immunology, Viral Nonstructural Proteins, medicine.disease_cause, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Antigen, Cell Line, Tumor, HLA-A2 Antigen, medicine, Animals, Humans, Immunology and Allergy, business.industry, Liver Neoplasms, T-cell receptor, virus diseases, Immunotherapy, Hepatitis C, medicine.disease, digestive system diseases, Genes, T-Cell Receptor, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Genetic Engineering, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb9458df968e5d83db209213dfbe4c8
https://doi.org/10.1007/s00262-016-1800-2

المؤلفون: Michael I. Nishimura, Elizabeth Garrett-Mayer, Timothy T. Spear, Kendra C. Foley

مصطلحات موضوعية: 0301 basic medicine, Leucine zipper, T cell, medicine.medical_treatment, Immunology, Receptors, Antigen, T-Cell, chemical and pharmacologic phenomena, Hepacivirus, Biology, CD8-Positive T-Lymphocytes, Cross Reactions, Jurkat cells, Immunotherapy, Adoptive, Article, 03 medical and health sciences, Jurkat Cells, 0302 clinical medicine, medicine, Immunology and Allergy, Humans, Gene, T-cell receptor, hemic and immune systems, Cell Biology, Immunotherapy, Hepatitis C, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Pairing, CD8, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6d651875af5c887045185a91160f31
https://europepmc.org/articles/PMC6133711/

المؤلفون: Hugo R. Rosen, Yuan Wang, Rachel H. McMahan, Lance M. Hellman, Michael I. Nishimura, Craig W. Vander Kooi, Kurt H. Piepenbrink, Timothy T. Spear, Nishant K. Singh, Brian M. Baker

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 114(24)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Isoantigens, T-Lymphocytes, Receptors, Antigen, T-Cell, chemical and pharmacologic phenomena, Hepacivirus, Cross Reactions, Viral Nonstructural Proteins, Major histocompatibility complex, Crystallography, X-Ray, Epitope, Cell Line, Major Histocompatibility Complex, 03 medical and health sciences, Epitopes, Jurkat Cells, 0302 clinical medicine, Protein Domains, HLA-A2 Antigen, Humans, Amino Acid Sequence, Allorecognition, Receptor, NS3, Multidisciplinary, biology, T-cell receptor, Molecular Mimicry, MHC restriction, 030104 developmental biology, HEK293 Cells, PNAS Plus, Immunology, biology.protein, Immunotherapy, Central tolerance, Peptides, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfcdea1fbebc99f53b77becafd6f126
https://pubmed.ncbi.nlm.nih.gov/28572406

المؤلفون: Michael I. Nishimura, Timothy T. Spear, Patricia E. Simms

المصدر: Journal of leukocyte biology. 102(2)

مصطلحات موضوعية: 0301 basic medicine, T-Lymphocytes, Immunology, Fluorescent Antibody Technique, Biology, Bioinformatics, Machine learning, computer.software_genre, Systems Biology & Immunogenetics, 03 medical and health sciences, Software analytics, Software, Immunology and Allergy, Humans, Instrumentation (computer programming), Representation (mathematics), business.industry, Computational Biology, Usability, Cell Biology, Flow Cytometry, Expression (mathematics), Shared resource, 030104 developmental biology, Flow (mathematics), Artificial intelligence, business, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133b53db79976af22fb513ff8414baae
https://pubmed.ncbi.nlm.nih.gov/28550117

المؤلفون: Kendra C. Foley, Timothy T. Spear, Yuan Wang, Patricia E. Simms, Michael I. Nishimura, David C. Murray, Gina Scurti, Lance M. Hellman, Elizabeth Garrett-Mayer, Brian M. Baker

المصدر: Cancer immunology, immunotherapy : CII. 66(11)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Adoptive cell transfer, T cell, T-Lymphocytes, Immunology, Receptors, Antigen, T-Cell, chemical and pharmacologic phenomena, Biology, Viral Nonstructural Proteins, Binding, Competitive, Article, Cell Line, 03 medical and health sciences, Interferon-gamma, Jurkat Cells, Mice, 0302 clinical medicine, Antigen, Cell Line, Tumor, medicine, Immunology and Allergy, Animals, Humans, Receptor, T-cell receptor, hemic and immune systems, Hep G2 Cells, Flow Cytometry, Adoptive Transfer, Coculture Techniques, 030104 developmental biology, medicine.anatomical_structure, HEK293 Cells, Oncology, T-Cell Receptor Gene, Cancer research, Peptides, CD8, Function (biology), 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545468a290b7bf095d80814f8f6e02f0
https://pubmed.ncbi.nlm.nih.gov/28634816

المؤلفون: Michael I. Nishimura, Yuan Wang, Brian G. Pierce, Sydney J. Blevins, Nishant K. Singh, Timothy T. Spear, Timothy P. Riley, Zhiping Weng, Brian M. Baker

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, media_common.quotation_subject, Receptors, Antigen, T-Cell, alpha-beta, Static Electricity, chemical and pharmacologic phenomena, Computational biology, Biology, Major histocompatibility complex, Adaptability, Class I MHC protein, 03 medical and health sciences, 0302 clinical medicine, HLA-A2 Antigen, Humans, Receptor, Gene, media_common, Genetics, Multidisciplinary, T-cell receptor, hemic and immune systems, MHC restriction, Tcr repertoire, 030104 developmental biology, PNAS Plus, biology.protein, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fcaf1204df7b286afb587717748d0a
https://europepmc.org/articles/PMC4780628/

المؤلفون: Orrin S. Belden, Yuan Wang, Timothy P. Riley, Timothy T. Spear, Lawrence J. Stern, Michael I. Nishimura, Brian M. Baker, Sydney J. Blevins, Liusong Yin, Lance M. Hellman

المصدر: Journal of immunological methods. 432

مصطلحات موضوعية: 0301 basic medicine, Circular dichroism, Protein Denaturation, Hot Temperature, Immunology, Kinetics, Peptide, Plasma protein binding, Major histocompatibility complex, Epitope, Fluorescence spectroscopy, Article, 03 medical and health sciences, HLA-A2 Antigen, Immunology and Allergy, Humans, Thermal stability, Fluorometry, chemistry.chemical_classification, 030102 biochemistry & molecular biology, biology, Chemistry, Protein Stability, Circular Dichroism, HLA-DR1 Antigen, Crystallography, 030104 developmental biology, biology.protein, Biophysics, Peptides, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e126fda86adda762cce675de15f5e1
https://pubmed.ncbi.nlm.nih.gov/26906089

المؤلفون: Timothy T. Spear, Kaoru Nagato, Michael I. Nishimura

المصدر: Cancer Drug Discovery and Development ISBN: 9783319211664

مصطلحات موضوعية: biology, Chemistry, T cell, T-cell receptor, chemical and pharmacologic phenomena, Streptamer, Major histocompatibility complex, Chimeric antigen receptor, Cell biology, Immune system, medicine.anatomical_structure, Antigen, medicine, biology.protein, Thymic T cell selection

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cabd7febcd2527372874d9306f23b0fe
https://doi.org/10.1007/978-3-319-21167-1_4

المؤلفون: Timothy T Spear, Timothy Riley, Kendra C Foley, David C Murray, Patricia E Simms, Gina M Scurti, Yuan Wang, Lance M Hellman, Rachel H McMahan, Hugo R Rosen, Brian M Baker, Michael I Nishimura

المصدر: The Journal of Immunology. 196:214.15-214.15

مصطلحات موضوعية: Immunology, Immunology and Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::af546171cf81167f70b79477be9cdd9d
https://doi.org/10.4049/jimmunol.196.supp.214.15