المؤلفون: Cecilia Wieder, Juliette Cooke, Clement Frainay, Nathalie Poupin, Russell Bowler, Fabien Jourdan, Katerina J Kechris, Rachel Pj Lai, Timothy Ebbels

المصدر: PLoS Computational Biology, Vol 20, Iss 3, p e1011814 (2024)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011814&type=printable; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/d2cc81da3c5e4dfc905dda29ad6a12c4

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

المصدر: PLoS Computational Biology, Vol 20, Iss 2, p e1011381 (2024)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/addb1baefa6e45aa91346ae67d1b18df

المؤلفون: Cecilia Wieder, Clément Frainay, Nathalie Poupin, Pablo Rodríguez-Mier, Florence Vinson, Juliette Cooke, Rachel Pj Lai, Jacob G Bundy, Fabien Jourdan, Timothy Ebbels

المصدر: PLoS Computational Biology, Vol 17, Iss 9, p e1009105 (2021)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/38f5454156524f19b62777d46227717a

المؤلفون: Qian Gao, Lars O. Dragsted, Timothy Ebbels

المصدر: Metabolites, Vol 9, Iss 5, p 92 (2019)

مصطلحات موضوعية: time series, PLS, NPLS, variable selection, bootstrapped-VIP, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2218-1989/9/5/92; https://doaj.org/toc/2218-1989

URL الوصول: https://doaj.org/article/2bd0448b088d4ef6a2b6888e98bd2ee5

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/journal_contribution/S1_Text_-/25269733

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.s001
https://figshare.com/articles/journal_contribution/S1_Text_-/25269733

المؤلفون: Cecilia Wieder (11402540), Clément Frainay (5958866), Nathalie Poupin (195134), Pablo Rodríguez-Mier (10131734), Florence Vinson (820339), Juliette Cooke (11402543), Rachel PJ Lai (8281866), Jacob G. Bundy (164702), Fabien Jourdan (216798), Timothy Ebbels (2247136)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Biotechnology, Cancer, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, several practical implications, minimal reporting guidelines, first step towards, evaluated using three, biocyc ), led, pathway database used, pathway database choice, significantly enriched pathways, vastly different results, specific background set, pathway analysis, positive pathways, background set, %22">xlink ">, representation analysis, pronounced impact, large numbers, functional interpretation, compound identification, chemical bias

Relation: https://figshare.com/articles/journal_contribution/Supplementary_figures_and_tables_/16582619

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009105.s001

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/Predicted_ranks_for_the_metabolites_present_in_a_ratio_significantly_associated_with_the_rs603424_SNP_/25269763

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g008
https://figshare.com/articles/figure/Predicted_ranks_for_the_metabolites_present_in_a_ratio_significantly_associated_with_the_rs603424_SNP_/25269763

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/ChemRich_enrichment_of_the_top_50_most_changed_metabolites_for_SCD_/25269775

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g012
https://figshare.com/articles/figure/ChemRich_enrichment_of_the_top_50_most_changed_metabolites_for_SCD_/25269775

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/Accuracy_plot_for_every_rank_cut-off_threshold_for_the_IEM_dataset_/25269757

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g006
https://figshare.com/articles/figure/Accuracy_plot_for_every_rank_cut-off_threshold_for_the_IEM_dataset_/25269757

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/Z-score_based_ranks_left_side_of_each_plot_vs_using_the_difference_between_means_right_side_of_left_plot_or_medians_right_side_of_right_plot_to_rank_metabolites_/25269751

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g004
https://figshare.com/articles/figure/Z-score_based_ranks_left_side_of_each_plot_vs_using_the_difference_between_means_right_side_of_left_plot_or_medians_right_side_of_right_plot_to_rank_metabolites_/25269751

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/dataset/Significant_metabolites_for_SCD_from_Suhre_i_et_al_i_converted_to_Human1_identifiers_/25269739

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.s003
https://figshare.com/articles/dataset/Significant_metabolites_for_SCD_from_Suhre_i_et_al_i_converted_to_Human1_identifiers_/25269739

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/Combining_metabolomics_profiling_with_simulations_of_metabolism_/25269742

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g001
https://figshare.com/articles/figure/Combining_metabolomics_profiling_with_simulations_of_metabolism_/25269742

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/Observed_and_predicted_changes_for_the_five_metabolites_significantly_associated_with_the_rs603424_SNP_/25269760

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g007
https://figshare.com/articles/figure/Observed_and_predicted_changes_for_the_five_metabolites_significantly_associated_with_the_rs603424_SNP_/25269760

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/Hypergeometric_test_p-values_for_different_rank_cut-off_values_for_SCD_/25269769

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g010
https://figshare.com/articles/figure/Hypergeometric_test_p-values_for_different_rank_cut-off_values_for_SCD_/25269769

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/Methodology_for_the_comparison_of_flux_values_and_prediction_of_metabolite_ranks_/25269745

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g002
https://figshare.com/articles/figure/Methodology_for_the_comparison_of_flux_values_and_prediction_of_metabolite_ranks_/25269745

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/Flux_Variability_Analysis_FVA_and_sampling_/25269748

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g003
https://figshare.com/articles/figure/Flux_Variability_Analysis_FVA_and_sampling_/25269748

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/Flux_bounds_FVA_and_distributions_sampling_for_urate_and_hypoxanthine_/25269754

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g005
https://figshare.com/articles/figure/Flux_bounds_FVA_and_distributions_sampling_for_urate_and_hypoxanthine_/25269754

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/SAMBA_ranks_for_the_metabolites_involved_in_significant_ratios_for_the_ACADS_SNP_from_Suhre_i_et_al_i_2011_/25269766

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g009
https://figshare.com/articles/figure/SAMBA_ranks_for_the_metabolites_involved_in_significant_ratios_for_the_ACADS_SNP_from_Suhre_i_et_al_i_2011_/25269766

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/ChemRich_enrichment_of_the_top_N_most_changed_metabolites_for_SCD_/25269778

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g013
https://figshare.com/articles/figure/ChemRich_enrichment_of_the_top_N_most_changed_metabolites_for_SCD_/25269778

المؤلفون: Juliette Cooke, Maxime Delmas, Cecilia Wieder, Pablo Rodríguez Mier, Clément Frainay, Florence Vinson, Timothy Ebbels, Nathalie Poupin, Fabien Jourdan

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, strong added value, snp associations found, measuring small molecules, circulating biofluid levels, human health studies, external transport reactions, scale metabolic networks, right metabolomics experiment, exchange reactions following, suggest new metabolites, simulated flux distributions, div >< p, disease database omim, based modelling approach, given metabolic perturbation, design metabolomics studies, exchange reactions, mgwas studies, metabolic trait

Relation: https://figshare.com/articles/figure/Hierarchical_BiNChE_CHEBI_graph_/25269772

الاتاحة: https://doi.org/10.1371/journal.pcbi.1011381.g011
https://figshare.com/articles/figure/Hierarchical_BiNChE_CHEBI_graph_/25269772