المؤلفون: Thabatta L. S. A. Rosa, Maria Angela M. Marques, Zachary DeBoard, Kelly Hutchins, Carlos Adriano A. Silva, Christine R. Montague, Tianao Yuan, Julio J. Amaral, Georgia C. Atella, Patrícia S. Rosa, Katherine A. Mattos, Brian C. VanderVen, Ramanuj Lahiri, Nicole S. Sampson, Patrick J. Brennan, John T. Belisle, Maria Cristina V. Pessolani, Marcia Berrêdo-Pinho

المصدر: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

مصطلحات موضوعية: Mycobacterium leprae, cholesterol, cholestenone, PGL-I, PDIM, 3β-HSD, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2021.765326/full; https://doaj.org/toc/2235-2988

URL الوصول: https://doaj.org/article/b7cdfbc411e443f0854efac06d6e89e4

المؤلفون: Thabatta L. S. A. Rosa, Maria Angela M. Marques, Zachary DeBoard, Kelly Hutchins, Carlos Adriano A. Silva, Christine R. Montague, Tianao Yuan, Julio J. Amaral, Georgia C. Atella, Patrícia S. Rosa, Katherine A. Mattos, Brian C. VanderVen, Ramanuj Lahiri, Nicole S. Sampson, Patrick J. Brennan, John T. Belisle, Maria Cristina V. Pessolani, Marcia Berrêdo-Pinho

المصدر: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

مصطلحات موضوعية: Mycobacterium leprae, cholesterol, cholestenone, PGL-I, PDIM, 3β-HSD, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2021.709972/full; https://doaj.org/toc/2235-2988

URL الوصول: https://doaj.org/article/8febf0d55d394f6994a5972e33c674cd

المؤلفون: Tianao Yuan (4862764), Joshua M. Werman (9173872), Xingyu Yin (10536626), Meng Yang (162251), Miguel Garcia-Diaz (1316169), Nicole S. Sampson (495978)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Inorganic Chemistry, Hematology, Infectious Diseases, Chemical Sciences not elsewhere classified, dehydrogenation steps, Cholesterol Side Chain, sequential stereospecific hydration, NAD, hydratase, catalyzes formation, enoyl-CoA substrate, Mtb genome, genomic locus, catalyzes dehydrogenation, Mycobacterium tuberculosis Bifurcat., cholesterol catabolism, contrast, chsH 3, MaoC-like family, crotonase family, Mycobacterium tuberculosis, 22 S hydration, Rossmann-fold motif, homodimeric structure, chsB 1, ChsH 3 product, ChsB 1 apo-protein

Relation: https://figshare.com/articles/journal_contribution/Enzymatic_Oxidation_of_the_Cholesterol_Side_Chain_in_i_Mycobacterium_tuberculosis_i_Bifurcates_Stereospecifically_at_Hydration_of_3_Oxo-cholest-4_22-dien-24-oyl-CoA/14384687

الاتاحة: https://doi.org/10.1021/acsinfecdis.1c00069.s001

المؤلفون: Tianao Yuan (6441632), Joshua Werman (10109395), Xingyu Yin (10109397), Meng Yang (10109400), Miguel Garcia-Diaz (10109401), Nicole Sampson (4405888)

مصطلحات موضوعية: Biochemistry, Chemical Biology, Microbiology, stereochemistry, beta-oxidation, cholesterol metabolism, Infectious Disease, catabolism pathways

Relation: https://figshare.com/articles/preprint/Enzymatic_-Oxidation_of_the_Cholesterol_Side_Chain_in_Mycobacterium_Tuberculosis_Bifurcates_Stereospecifically_at_Hydration_of_3-Oxo-Cholest-4_22-_Dien-24-Oyl-CoA/13728112

الاتاحة: https://doi.org/10.26434/chemrxiv.13728112.v1

المؤلفون: Nicole S. Sampson, Tianao Yuan, Joshua M. Werman

المصدر: RSC Chem Biol

مصطلحات موضوعية: 0301 basic medicine, Drug, Tuberculosis, business.industry, Drug discovery, media_common.quotation_subject, 030106 microbiology, Context (language use), Computational biology, medicine.disease, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, Article, Unmet needs, 03 medical and health sciences, 030104 developmental biology, Mechanism of action, Chemistry (miscellaneous), Medicine, medicine.symptom, business, Whole cell, Molecular Biology, Tb treatment, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a7fe10dad63ef7e4cf3e842d51ff74
https://doi.org/10.1039/d0cb00226g

المؤلفون: Nicole S. Sampson, Rui Lu, Joshua M. Werman, Tianao Yuan, Natasha M. Nesbitt, Amber C. Bonds, Miguel Garcia-Diaz, Jungwon Jang

المصدر: ACS Infectious Diseases. 6:2214-2224

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Chemistry, Cholesterol, Catabolism, 030106 microbiology, Lysine, Catabolite repression, Enoyl-CoA hydratase, 03 medical and health sciences, Succinylation, chemistry.chemical_compound, 030104 developmental biology, Infectious Diseases, Enzyme, Biochemistry, Binding site

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b0df48c12d219c125ac94c350e63ecab
https://doi.org/10.1021/acsinfecdis.0c00329

المؤلفون: John E. Gadbery, Jie Liu, Israël Casabon, Nicole S. Sampson, Xinxin Yang, Lindsay D. Eltis, Tianao Yuan, James W. Round, Keith T Story, Matthew F. Wipperman, Adam M. Crowe

المصدر: Biochemistry

مصطلحات موضوعية: Operon, medicine.medical_treatment, Coenzyme A, Biochemistry, Acyl-CoA Dehydrogenase, Article, Steroid, ACADS, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Coenzyme A Ligases, medicine, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, 030306 microbiology, Catabolism, Mycobacterium smegmatis, Mycobacterium tuberculosis, biology.organism_classification, Heterotetramer, 3. Good health, Cholesterol, Enzyme, chemistry, Steroids, Acyl Coenzyme A

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c46afd01103899593f37a9c24fb299
https://doi.org/10.1021/acs.biochem.0c00005

المؤلفون: Rui Ma, Nicole S. Sampson, Scott G. Franzblau, Harm van Bakel, Melissa Smith, Robert Sebra, Gintaras Deikus, Tianao Yuan, Kieran I. Chacko, Xinxin Yang, Andrew Kasarskis

المصدر: ACS Infectious Diseases. 5:1239-1251

مصطلحات موضوعية: 0301 basic medicine, Tuberculosis, 030106 microbiology, Population, Antitubercular Agents, Down-Regulation, Biology, Regulon, Microbiology, Small Molecule Libraries, Mycobacterium tuberculosis, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Minimum inhibitory concentration, Bacterial Proteins, Drug tolerance, Drug Resistance, Bacterial, Isoniazid, medicine, Diarylquinolines, education, education.field_of_study, Molecular Structure, Drug Synergism, Gene Expression Regulation, Bacterial, biology.organism_classification, medicine.disease, 3. Good health, 030104 developmental biology, Infectious Diseases, chemistry, Azasteroids, Bedaquiline, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3811109c65cb6c38b5f946d32ee3cc4c
https://doi.org/10.1021/acsinfecdis.9b00099

المؤلفون: Tianao, Yuan, Joshua M, Werman, Xingyu, Yin, Meng, Yang, Miguel, Garcia-Diaz, Nicole S, Sampson

المصدر: ACS Infectious Diseases

مصطلحات موضوعية: Cholesterol, catabolism, Rv3502c, stereochemistry, Coenzyme A, Mycobacterium tuberculosis, Enoyl-CoA Hydratase, Oxidation-Reduction, Article, Rv3538

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b42e8425339854084f0330753f81df93
https://pubmed.ncbi.nlm.nih.gov/33826843

المؤلفون: Amber C, Bonds, Tianao, Yuan, Joshua M, Werman, Jungwon, Jang, Rui, Lu, Natasha M, Nesbitt, Miguel, Garcia-Diaz, Nicole S, Sampson

المصدر: ACS Infect Dis

مصطلحات موضوعية: Kinetics, Cholesterol, Bacterial Proteins, Mycobacterium tuberculosis, Enoyl-CoA Hydratase, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f7e6c0369fede26c6666c443ff0cac83
https://pubmed.ncbi.nlm.nih.gov/32649175

المؤلفون: Thabatta L. S. A. Rosa (11195667), Maria Angela M. Marques (11195670), Zachary DeBoard (11195673), Kelly Hutchins (10914153), Carlos Adriano A. Silva (11195676), Christine R. Montague (11195679), Tianao Yuan (4862764), Julio J. Amaral (11195682), Georgia C. Atella (8635944), Patrícia S. Rosa (8893214), Katherine A. Mattos (11195685), Brian C. VanderVen (11195688), Ramanuj Lahiri (449588), Nicole S. Sampson (495978), Patrick J. Brennan (168870), John T. Belisle (188824), Maria Cristina V. Pessolani (8635956), Marcia Berrêdo-Pinho (6636707)

مصطلحات موضوعية: Clinical Microbiology, Medical Bacteriology, Medical Infection Agents (incl. Prions), Medical Virology, Mycobacterium leprae, cholesterol, cholestenone, PGL-I, PDIM, 3β-HSD, reductive power, oxidation

Relation: https://figshare.com/articles/figure/Image_3_Reductive_Power_Generated_by_Mycobacterium_leprae_Through_Cholesterol_Oxidation_Contributes_to_Lipid_and_ATP_Synthesis_tif/15065868

الاتاحة: https://doi.org/10.3389/fcimb.2021.709972.s003

المؤلفون: Nicole S. Sampson, Tianao Yuan

المصدر: Chemical Reviews

مصطلحات موضوعية: 0301 basic medicine, Tuberculosis, 030106 microbiology, Antitubercular Agents, Disease, Review, Genome, Mycobacterium tuberculosis, 03 medical and health sciences, Drug Discovery, medicine, Humans, Granuloma, Single model, biology, Genome, Human, Extramural, Chemistry, Drug discovery, General Chemistry, biology.organism_classification, medicine.disease, Virology, 3. Good health, 030104 developmental biology, Drug development

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b205f56b8762c5159804bca9a8aa0faf
http://europepmc.org/articles/PMC5832989

المؤلفون: Kalle Gehring, Nicole S. Sampson, Meng Yang, Tianao Yuan

المصدر: Biochemistry

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, biology, Operon, 030302 biochemistry & molecular biology, Mutagenesis, Aldolase A, Dehydrogenase, Protomer, Enoyl-CoA hydratase, Biochemistry, Article, 3. Good health, 03 medical and health sciences, Enzyme, chemistry, biology.protein, Bond cleavage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e8cb6f2fa945f5a416ff5d9f6ec91f
https://europepmc.org/articles/PMC6946549/

المؤلفون: Xisheng Zeng, Hongliang Ying, Surong Huang, Tianao Yuan, Qi Zhang

المصدر: 2019 22nd International Conference on Electrical Machines and Systems (ICEMS).

مصطلحات موضوعية: 010302 applied physics, Computer science, Rotor (electric), business.industry, 020208 electrical & electronic engineering, Automotive industry, 02 engineering and technology, 01 natural sciences, Automotive engineering, Magnetic flux, law.invention, Finite element simulation, Quantitative Biology::Subcellular Processes, law, Magnet, 0103 physical sciences, 0202 electrical engineering, electronic engineering, information engineering, Waveform, Point (geometry), Synchronous motor, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c51b45c45a4b217cf85e8bee9477acaa
https://doi.org/10.1109/icems.2019.8921622

المؤلفون: Xinxin Yang, Tianao Yuan, Rui Ma, Kieran Chacko, Melissa Smith, Gintaras Deikus, Robert Sebra, Andrew Kasarskis, Harm van Bakel, Scott G. Franzblau, Nicole Sampson

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c9bfa2b1659eb08d1754ea449abd1d
https://doi.org/10.26434/chemrxiv.5901226

المؤلفون: Jingwei Zhu, Yueling Liu, Yu Qin, Dechen Jiang, Tianao Yuan

المصدر: Sensors and Actuators B: Chemical. 219:100-104

مصطلحات موضوعية: chemistry.chemical_classification, Detection limit, Materials science, Metals and Alloys, Ionophore, chemistry.chemical_element, Polymer, Carbon nanotube, Condensed Matter Physics, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, law.invention, Membrane, chemistry, law, Electrode, Materials Chemistry, Electrical and Electronic Engineering, Composite material, Selectivity, Instrumentation, Carbon

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::87dc594498f5801d44e9916139024870
https://doi.org/10.1016/j.snb.2015.04.122

المؤلفون: Nicole S. Sampson, Ma R, Yang X, Tianao Yuan, Scott G. Franzblau

مصطلحات موضوعية: music.instrument, Tuberculosis, Cholesterol, Operon, Long-term potentiation, Biology, medicine.disease, biology.organism_classification, Azasteroid, Microbiology, Mycobacterium tuberculosis, chemistry.chemical_compound, Regulon, chemistry, medicine, Bedaquiline, music

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0429c07c3fe1e191978636f896ee1c15
https://doi.org/10.26434/chemrxiv.5901226.v1

المؤلفون: Bonds, Amber C., Tianao Yuan, Werman, Joshua M., Jungwon Jang, Rui Lu, Nesbitt, Natasha M., Garcia-Diaz, Miguel, Sampson, Nicole S.

المصدر: ACS Infectious Diseases; 8/14/2020, Vol. 6 Issue 8, p2214-2224, 11p

المؤلفون: Tianao Yuan¹, Sampson, Nicole S.^1,2 nicole.sampson@stonybrook.edu

المصدر: Chemical Reviews. 2/28/2018, Vol. 118 Issue 4, p1887-1916. 30p.

مصطلحات موضوعية: *TUBERCULOSIS treatment, *DRUG development, *GENOMES